Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis

Estrogen-dependent osteoarthritis (EDPOA) is a disease of perimenopausal-age women. Their manifestations are polyarticular pain with common co-morbidities (carpal tunnel syndrome, insomnia, fatigue, depression, and fibromyalgia). Based on dual role of glucocorticoids, its trophic action on the chond...

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Autores:
Cañas, Carlos Alberto
Bonilla-Abadía, Fabio
Izquierdo, Jorge H.
Cepeda, Magda C.
Coronel Restrepo, Nicolás
Osorio, Carlos J.
Tipo de recurso:
Article of investigation
Fecha de publicación:
2014
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/78521
Acceso en línea:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84901291205&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78521
http://dx.doi.org/10.1007/s00296-012-2603-1
Palabra clave:
Ciencias socio biomédicas
Esteroides
Steroids
Biomedical sciences
Medical sciences
Menopausia
Menopause
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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oai_identifier_str oai:repository.icesi.edu.co:10906/78521
network_acronym_str ICESI2
network_name_str Repositorio ICESI
repository_id_str
spelling Cañas, Carlos AlbertoBonilla-Abadía, FabioIzquierdo, Jorge H.Cepeda, Magda C.Coronel Restrepo, NicolásOsorio, Carlos J.cacd12@hotmail.comHeidelberg de Lat: 49 25 00 N degrees minutes Lat: 49.4167 decimal degrees Long: 008 42 00 E degrees minutes Long: 8.7000 decimal degrees2015-10-14T21:57:28Z2015-10-14T21:57:28Z2014-05-011437-160Xhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84901291205&partnerID=tZOtx3y1http://hdl.handle.net/10906/78521http://dx.doi.org/10.1007/s00296-012-2603-1instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Estrogen-dependent osteoarthritis (EDPOA) is a disease of perimenopausal-age women. Their manifestations are polyarticular pain with common co-morbidities (carpal tunnel syndrome, insomnia, fatigue, depression, and fibromyalgia). Based on dual role of glucocorticoids, its trophic action on the chondrocyte and its anti-inflammatory effect, we conducted a prospective interventional cohort study where we evaluate the efficacy and safety of oral low-dose GC in one hundred women with EDPOA. The pain intensity, number of tender joints as well as impact in co-morbidities were analyzed. We conclude that the use of low-dose GC in patients with EDPOA can be an effective and a safe therapeutic option. © 2013 Springer-Verlag.2 páginasDigitalengSpringer VerlagFacultad de Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasHeidelbergRheumatology InternationalRheumatology International; Vol. 34 No. 5EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Todo persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasEsteroidesSteroidsBiomedical sciencesMedical sciencesMenopausiaMenopauseEfficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritisinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1ArtículoComunidad Universidad Icesi - Investigadores3455733735ORIGINALdocumento.htmldocumento.htmltext/html293http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78521/1/documento.html6b1fe62dadbcb925bcabb05a2fbd1801MD5110906/78521oai:repository.icesi.edu.co:10906/785212018-10-26 16:26:35.812Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
title Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
spellingShingle Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
Ciencias socio biomédicas
Esteroides
Steroids
Biomedical sciences
Medical sciences
Menopausia
Menopause
title_short Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
title_full Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
title_fullStr Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
title_full_unstemmed Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
title_sort Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
dc.creator.fl_str_mv Cañas, Carlos Alberto
Bonilla-Abadía, Fabio
Izquierdo, Jorge H.
Cepeda, Magda C.
Coronel Restrepo, Nicolás
Osorio, Carlos J.
dc.contributor.author.spa.fl_str_mv Cañas, Carlos Alberto
Bonilla-Abadía, Fabio
Izquierdo, Jorge H.
Cepeda, Magda C.
Coronel Restrepo, Nicolás
Osorio, Carlos J.
dc.subject.none.fl_str_mv Ciencias socio biomédicas
Esteroides
Steroids
Biomedical sciences
topic Ciencias socio biomédicas
Esteroides
Steroids
Biomedical sciences
Medical sciences
Menopausia
Menopause
dc.subject.spa.fl_str_mv Medical sciences
Menopausia
Menopause
description Estrogen-dependent osteoarthritis (EDPOA) is a disease of perimenopausal-age women. Their manifestations are polyarticular pain with common co-morbidities (carpal tunnel syndrome, insomnia, fatigue, depression, and fibromyalgia). Based on dual role of glucocorticoids, its trophic action on the chondrocyte and its anti-inflammatory effect, we conducted a prospective interventional cohort study where we evaluate the efficacy and safety of oral low-dose GC in one hundred women with EDPOA. The pain intensity, number of tender joints as well as impact in co-morbidities were analyzed. We conclude that the use of low-dose GC in patients with EDPOA can be an effective and a safe therapeutic option. © 2013 Springer-Verlag.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014-05-01
dc.date.accessioned.none.fl_str_mv 2015-10-14T21:57:28Z
dc.date.available.none.fl_str_mv 2015-10-14T21:57:28Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
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format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.none.fl_str_mv 1437-160X
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10906/78521
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1007/s00296-012-2603-1
dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
dc.identifier.reponame.none.fl_str_mv reponame: Biblioteca Digital
dc.identifier.repourl.none.fl_str_mv repourl: https://repository.icesi.edu.co/
identifier_str_mv 1437-160X
instname: Universidad Icesi
reponame: Biblioteca Digital
repourl: https://repository.icesi.edu.co/
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84901291205&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78521
http://dx.doi.org/10.1007/s00296-012-2603-1
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Rheumatology International
dc.relation.ispartofseries.none.fl_str_mv Rheumatology International; Vol. 34 No. 5
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.license.none.fl_str_mv Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.none.fl_str_mv 2 páginas
dc.format.medium.none.fl_str_mv Digital
dc.coverage.spatial.none.fl_str_mv Heidelberg de Lat: 49 25 00 N degrees minutes Lat: 49.4167 decimal degrees Long: 008 42 00 E degrees minutes Long: 8.7000 decimal degrees
dc.publisher.spa.fl_str_mv Springer Verlag
dc.publisher.faculty.none.fl_str_mv Facultad de Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Medicina
dc.publisher.department.spa.fl_str_mv Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv Heidelberg
institution Universidad ICESI
bitstream.url.fl_str_mv http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78521/1/documento.html
bitstream.checksum.fl_str_mv 6b1fe62dadbcb925bcabb05a2fbd1801
bitstream.checksumAlgorithm.fl_str_mv MD5
repository.name.fl_str_mv Biblioteca Digital - Universidad icesi
repository.mail.fl_str_mv cdcriollo@icesi.edu.co
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