Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá

Autores:: Rubio Gómez, Cladelis
Gutiérrez Castañeda, Luz Dary
Pedraza , Olga Lucia
Torres Tobar, Lilian
Hernández Acevedo, Gualberto
Suárez Camacho, Alfonso
Lozano Ruiz, Ángela Gisselle
Camacho-Bermúdez, Isis Norella

Tipo de recurso:: Article of journal

Fecha de publicación:: 2021

Institución:: Fundación Universitaria de Ciencias de la Salud - FUCS

Repositorio:: Repositorio Digital Institucional ReDi

Idioma:: spa

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dc.title.spa.fl_str_mv	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
dc.title.translated.eng.fl_str_mv	Genotypic and allelic frequencies of apolipoprotein e (APOE) in a sample of adults in bogotá
title	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
spellingShingle	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá Alzheimer APOE E2 E3 E4 PCR – tetraprimer Alzheimer, APOE, E2, E3, E4, tetraprimer PCR.
title_short	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
title_full	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
title_fullStr	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
title_full_unstemmed	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
title_sort	Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá
dc.creator.fl_str_mv	Rubio Gómez, Cladelis Gutiérrez Castañeda, Luz Dary Pedraza , Olga Lucia Torres Tobar, Lilian Hernández Acevedo, Gualberto Suárez Camacho, Alfonso Lozano Ruiz, Ángela Gisselle Camacho-Bermúdez, Isis Norella
dc.contributor.author.spa.fl_str_mv	Rubio Gómez, Cladelis Gutiérrez Castañeda, Luz Dary Pedraza , Olga Lucia Torres Tobar, Lilian Hernández Acevedo, Gualberto Suárez Camacho, Alfonso Lozano Ruiz, Ángela Gisselle Camacho-Bermúdez, Isis Norella
dc.subject.spa.fl_str_mv	Alzheimer APOE E2 E3 E4 PCR – tetraprimer
topic	Alzheimer APOE E2 E3 E4 PCR – tetraprimer Alzheimer, APOE, E2, E3, E4, tetraprimer PCR.
dc.subject.eng.fl_str_mv	Alzheimer, APOE, E2, E3, E4, tetraprimer PCR.
publishDate	2021
dc.date.accessioned.none.fl_str_mv	2021-07-19 17:15:26 2022-06-29T19:38:20Z
dc.date.issued.none.fl_str_mv	2021-07-19
dc.date.available.none.fl_str_mv	2021-07-19 17:15:26 2022-06-29T19:38:20Z
dc.type.spa.fl_str_mv	Artículo de revista
dc.type.eng.fl_str_mv	Journal article
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dc.identifier.doi.none.fl_str_mv	10.31260/RepertMedCir.01217372.1008
dc.identifier.issn.none.fl_str_mv	0121-7372
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dc.identifier.url.none.fl_str_mv	https://doi.org/10.31260/RepertMedCir.01217372.1008
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dc.relation.references.spa.fl_str_mv	MedlinePlus Connect for EHRs. APOE gene, apolipoprotein E [Internet]. MedlinePlus; 2020 [cited 2019 septiembre 14]; Available from: https://medlineplus.gov/genetics/gene/apoe/. 2. Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci. 2006;103(15):5644-51. doi: 10.1073/pnas.0600549103 3. Rall SC Jr, Weisgraber KH, Innerarity TL, Mahley RW Structural basis for receptor binding heterogeneity of Apolipoprotein E from type III hyperlipoproteinemic subjects. Proc Natl Acad Sci U S A. 1982;79(15):4696-700. doi: 10.1073/pnas.79.15.4696 4. Wilson C, Wardell MR, Weisgraber KH, Mahley RW, Agard DA. Three-dimensional structure of the LDL receptor-binding doamin of human apolipoprotein E. Science. 1991;252(5014):1817-22. doi: 10.1126/science.2063194 5. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31:545-8. 6. Weisgraber KH, Rall SC, Jr., Mahley RW. Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms. J BiolChem. 1981;256 (17):9077-83. doi: 10.1016/s0021-9258(19)52510-8 7. Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis. 1988; (1):1-21. doi: 10.1161/01.atv.8.1.1 8. Huebbe P, Rimbach G. Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors. Ageing Res Rev. 2017;37:146-61. doi: 10.1016/j.arr.2017.06.002 9. Singh PP, Singh M, Mastana SS. APOE distribution in world populations with new data from India and the UK. Ann Hum Biol. 2006;33(3):279-308. doi: 10.1080/03014460600594513 10. Gerdes LU, Gerdes C., Hansen PS, Klausen IC., Faergeman, O., Dyerberg J. 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Distribution of APOE polymorphism in the “Paisa” population from northwest Colombia (Antioquia). Ann Hum Biol 2014;42(2):195-8. doi: 10.3109/03014460.2014.932846 31. Landázuri P, Loango, N., Gallego, M. L., & Restrepo, B. Diferencias de sexo, edad y lípidos plasmáticos asociadas al polimorfismo de la apolipoproteína E en un grupo de escolares de Quindío, Colombia. Biomédica. 2009;29(3):382-91. doi: 10.7705/biomedica.v29i3.10 32. Ruiz M, Arias, I., Rolon, G., Hernández, E., Garavito, P., & Silvera-Redondo, C. A. Análisis del polimorfismo del gen APOE en la población de Barranquilla, Colombia. Biomédica. 2015;36(1):52-58. doi: 10.7705/biomedica.v36i1.2612 33. Jaramillo-Correa JP, Keyeux, G., Ruiz-Garcia, M., Rodas, C., & Bernal, J. Population genetic analysis of the genes APOE, APOB (3′ VNTR) and ACE in some black and Amerindian communities from Colombia. Human Hered. 2001;52(1):14-33. doi: 10.1159/000053351 34. Pedraza OL, Salazar AM, Sierra FA, Montalvo C, Muñoz Y, Díaz JM, et al. Mild cognitive impairment (MCI) and dementia in a sample of adults in the city of Bogotá. Dement Neuropsychol 2017;11(3):262-26. doi: 10.1590/1980-57642016dn11-030008 35. Yang YG KJ, Park SJ, Kim SW, Jeon O, Kim D. Apolipoprotein E genotyping by multiplex tetra-primer amplification refractory mutation system PCR in single reaction tube. J Biotechnol. 2007;131(2):106-10. doi: 10.1016/j.jbiotec.2007.06.001 36. Bertram L, & Tanzi, R. E. Genome-wide association studies in Alzheimer's disease. Human molecular genetics. 2009;18(R2): R137-45. doi: 10.1093/hmg/ddp406 37. Caselli RJ, Dueck, A. C., Osborne, D., Sabbagh, M. N., Connor, D. J., Ahern, G. L., Baxter, L. C., Rapcsak, S. Z., Shi, J., Woodruff, B. K., Locke, D. E. C., Snyder, C. H., Alexander, G. E., Rademakers, R., Reiman, E. M. Longitudinal modeling of age-related memory decline and the APOE epsilon-4 effect. New Eng J Med. 2009;361(3):255-63. doi: 10.1056/NEJMoa0809437 38. Baxter LC CR, Johnson SC, Reiman E, Osborne D. Apolipoprotein E epsilon 4 affects new learning in cognitively normal individuals at risk for Alzheimer’s disease. Neurobiol Aging. 2003;24(7):947-52. doi: 10.1016/s0197-4580(03)00006-x 39. Caselli RJ RE, Osborne D, et al. Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOE e4 allele. Neurology. 2004;62(11): 1990-5. doi: 10.1212/01.wnl.0000129533.26544.bf 40. Caselli RJ RE, Locke DE, et al. Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment. Arch Neurol. 2007;64(9):1306-1311. 41. Reiman EM, Caselli, R. J., Chen, K., Alexander, G. E., Bandy, D., Frost, J. Declining brain activity in cognitively normal apolipoprotein E epsilon-4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Nat Acad Sci USA. 2001;98(6):3334-9. doi: 10.1073/pnas.061509598 42. Reiman EM, Caselli, R. J., Yun, L. S., Chen, K., Bandy, D., Minoshima, S., Thibodeau, S. N., Osborne, D. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon-4 allele for apolipoprotein E. New Eng J Med. 1996;334(12):752-8. doi: 10.1056/NEJM199603213341202 43. Reiman EM, Chen, K., Alexander, G. E., Caselli, R. J., Bandy, D., Osborne, D., Saunders, A. M., Hardy, J. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Nat Acad Sci. 2004;101(1):284-9. doi: 10.1073/pnas.2635903100 44. Marca V AO, Cornejo-Olivas M, Ortega O, Huerta D, Mazzetti P. Genetic polymorphism of apolipoprotein E in a Peruvian population. Rev Peru Med Exp Salud Publica. 2011;28(4):589-94. 45. Molero AE P-RrG, Maestre GE. Modulation by age and gender of risk for Alzheimer's disease and vascular dementia associated with the apolipoprotein E-ε4 allele in Latin Americans: findings from the Maracaibo Aging Study. Neuroscience letters. 2001;307(1):5-8. doi: 10.1016/S0304-3940(01)01911-5 46. Arráiz N, Bermudez V, Prieto C, Sánchez MP, Escalona C, Sanz E, Rondón N, Reyes F, Velasco M. Association between apoliprotein E gene polymorphism and hypercholesterolemic phenotype in Maracaibo, Zulia state, Venezuela. Am J Ther. 2010;17(3):330-6. doi: 10.1097/MJT.0b013e3181c1235d. 47. Paz-y-Miño C CC, López-Cortés A, Munoz MJ, Cumbal N, Castro B, Cabrera A, Sánchez ME. Genetic polymorphisms in apolipoprotein E and glutathione peroxidase 1 genes in the Ecuadorian population affected with Alzheimer's disease. Am J Med Sci. 2010;340(5):373-7. doi: 10.1097/MAJ.0b013e3181e93475 48. Souza DR, De Godoy MR, Hotta J, Tajara EH, Brandao AC, Pinheiro Júnior S, Tognola WA, Dos Santos JE. Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians. Braz J Med Biol Res. 2003;36(7):919-23. doi: 10.1590/s0100-879x2003000700013 49. De França E, Alves JG, Hutz MH. Apolipoprotein E polymorphism and its association with serum lipid levels in Brazilian children. Human Biol. 2004;76(2):267-75. 50. Fuzikawa AK PS, Taufer M, Moriguchi EH, Lima-Costa MF. Apolipoprotein E polymorphism distribution in an elderly Brazilian population: the Bambuí Health and Aging Study. Braz J Med Biol Res. 2007;40(11):1429-34. doi: 10.1590/s0100-879x2007001100002. 51. Brito DD, Fernandes AP, Gomes KB, Coelho FF, Cruz NG, Sabino AP, Cardoso JE, Figueiredo-Filho PP, Diamante R, Norton CR, Sousa MO. Apolipoprotein A5-1131T> C polymorphism, but not APOE genotypes, increases susceptibility for dyslipidemia in children and adolescents. Molecular Biology Reports. 2011;38(7):4381-8. doi: 10.1007/s11033-010-0565-5 52. Gayà‐Vidal M AG, Carreras‐Torres R, Via M, Esteban E, Villena M, Vasquez R, Dugoujon JM, Moral P. Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native Andean populations: Aymaras and Quechuas. Annals Hum Genet. 2012;76(4):283-95. doi: 10.1111/j.1469-1809.2012.00712.x 53.Quiroga P, Calvo C, Albala C, Urquidi J, Santos JE, Perez H, Klaassen G. Apolipoprotein E polymorphism in elderly Chilean people with Alzheimer’s disease. Neuroepidemiology. 1998;18(1):48-52. doi: 10.1159/000026195 54.Rollan A, Loyola G, Covarrubias C, Giancaspero R, Acevedo K, Nervi F. Apolipoprotein E polymorphism in patients with acute pancreatitis. Pancreas. 1994;9(3):349-53. doi: 10.1097/00006676-199405000-00011 55.Leiva E, Mujica V, Orrego R, Prieto M, Arredondo M. Apolipoprotein E polymorphism in type 2 diabetic patients of Talca, Chile. Diabetes research and clinical practice. 2005;68(3):244-9. doi: 10.1016/j.diabres.2004.09.017 56.Pedraza OL Camacho I, Sierra FA, Rubio-Gómez C, Salazar AM, Montalvo C, Morillo D, Lozano A, Gutiérrez-Castañeda LD, Torres-Tobar L, Piñeros C. Association between ε4 allele, cardio-metabolic and social risk factors in the development of cognitive impairment in elderly adults from Bogota. Sometido a publicación.
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spelling	Rubio Gómez, Cladelis59d3daa2c12228b61c0ef8cddea9a586500Gutiérrez Castañeda, Luz Dary3dc185dc305169c19168b1127cffe9c8Pedraza , Olga Luciaebec061b00edebe0a8670073edb61ef8Torres Tobar, Liliand83388c62f11bd3c44452135de804faaHernández Acevedo, Gualberto34341654e41cd161909136c75665cfd7300Suárez Camacho, Alfonso83cebe40f4c6bde591037018483d0ddf300Lozano Ruiz, Ángela Gisselle9ec62e7b06d8fe3a2cdbd9ebcfd4ede2300Camacho-Bermúdez, Isis Norelladf427a429cb3712fefe5a1f28c44aab43002021-07-19 17:15:262022-06-29T19:38:20Z2021-07-192021-07-19 17:15:262022-06-29T19:38:20ZSociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la SaludRevista Repertorio de Medicina y Cirugía - 2021info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/http://purl.org/coar/access_right/c_abf2https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/1008AlzheimerAPOEE2E3E4PCR – tetraprimerAlzheimer, APOE, E2, E3, E4, tetraprimer PCR.Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en BogotáGenotypic and allelic frequencies of apolipoprotein e (APOE) in a sample of adults in bogotáapplication/pdftext/htmlapplication/epub+ziptext/xmlaudio/mpegArtículo de revistaJournal articlehttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionTexthttp://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a8510.31260/RepertMedCir.01217372.10080121-7372https://repositorio.fucsalud.edu.co/handle/001/29622462-991Xhttps://doi.org/10.31260/RepertMedCir.01217372.1008spaMedlinePlus Connect for EHRs. APOE gene, apolipoprotein E [Internet]. MedlinePlus; 2020 [cited 2019 septiembre 14]; Available from: https://medlineplus.gov/genetics/gene/apoe/. 2. Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci. 2006;103(15):5644-51. doi: 10.1073/pnas.0600549103 3. Rall SC Jr, Weisgraber KH, Innerarity TL, Mahley RW Structural basis for receptor binding heterogeneity of Apolipoprotein E from type III hyperlipoproteinemic subjects. Proc Natl Acad Sci U S A. 1982;79(15):4696-700. doi: 10.1073/pnas.79.15.4696 4. Wilson C, Wardell MR, Weisgraber KH, Mahley RW, Agard DA. Three-dimensional structure of the LDL receptor-binding doamin of human apolipoprotein E. Science. 1991;252(5014):1817-22. doi: 10.1126/science.2063194 5. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31:545-8. 6. 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Association between ε4 allele, cardio-metabolic and social risk factors in the development of cognitive impairment in elderly adults from Bogota. Sometido a publicación.https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/1008/1502https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/1008/1608https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/1008/1627https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/1008/1663https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/1008/1643Núm. 2 , Año 2021 : Mayo - Agosto141213430Revista Repertorio de Medicina y CirugíaPublicationOREORE.xmltext/xml3120https://repositorio.fucsalud.edu.co/bitstreams/35246e59-b788-4141-a31d-a4aeb87c7493/download5ec6d252ddcd642c1a621b86e63ae7ebMD51001/2962oai:repositorio.fucsalud.edu.co:001/29622024-02-02 13:07:50.611https://creativecommons.org/licenses/by-nc-sa/4.0/Revista Repertorio de Medicina y Cirugía - 2021metadata.onlyhttps://repositorio.fucsalud.edu.coRepositorio Digital de la Fundación Universitaria de Ciencias de la Saludredi@fucsalud.edu.co

Frecuencias genotípicas y alélicas de apolipoproteina e (APOE) en una muestra de adultos en Bogotá

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