What does the literature say about using electronic pillboxes for older adults? A systematic literature review

Clinical studies used commercially well-established electronic pillboxes with a high TRL. New electronic pillboxes in development had a low TRL. The discovered outcome was mainly adherence to medication. The overall mean adherence to medication regimens for all the studies using an electronic pillbo...

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Autores:: Cruz , Antonio Miguel
Aya Parra, Pedro Antonio
Bóhorquez, Andrés Felipe

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2018

Institución:: Escuela Colombiana de Ingeniería Julio Garavito

Repositorio:: Repositorio Institucional ECI

Idioma:: eng

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dc.title.eng.fl_str_mv	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
title	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
spellingShingle	What does the literature say about using electronic pillboxes for older adults? A systematic literature review Pastillero electrónico Adultos mayores Electronic pillbox Older adults Centered design approach Pastillero electrónico Adultos mayores Enfoque de diseño centrado
title_short	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
title_full	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
title_fullStr	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
title_full_unstemmed	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
title_sort	What does the literature say about using electronic pillboxes for older adults? A systematic literature review
dc.creator.fl_str_mv	Cruz , Antonio Miguel Aya Parra, Pedro Antonio Bóhorquez, Andrés Felipe
dc.contributor.author.none.fl_str_mv	Cruz , Antonio Miguel Aya Parra, Pedro Antonio Bóhorquez, Andrés Felipe
dc.contributor.researchgroup.spa.fl_str_mv	GiBiome
dc.subject.armarc.none.fl_str_mv	Pastillero electrónico Adultos mayores
topic	Pastillero electrónico Adultos mayores Electronic pillbox Older adults Centered design approach Pastillero electrónico Adultos mayores Enfoque de diseño centrado
dc.subject.proposal.spa.fl_str_mv	Electronic pillbox Older adults Centered design approach Pastillero electrónico Adultos mayores Enfoque de diseño centrado
description	Clinical studies used commercially well-established electronic pillboxes with a high TRL. New electronic pillboxes in development had a low TRL. The discovered outcome was mainly adherence to medication. The overall mean adherence to medication regimens for all the studies using an electronic pillbox was higher than the gold standard of a good adherence level cut-off point (mean adherence 88.8%>80%). However, we found a large variation in this variable (SD = 10.7). With regard to an older adult population’s adherence to medication regimens, for the outcome variable of those who had undergone a kidney transplant, the clinical evidence that electronic pillboxes have a positive impact was strong (1b); for those with a chronic hepatitis C medical condition, the clinical evidence was medium (3), and for those with arterial hypertension and multiple chronic (diabetes and hypertension) medical conditions, the clinical evidence was weak (5).
publishDate	2018
dc.date.issued.none.fl_str_mv	2018
dc.date.accessioned.none.fl_str_mv	2021-06-03T20:28:04Z 2021-10-01T17:16:58Z
dc.date.available.none.fl_str_mv	2021-06-03 2021-10-01T17:16:58Z
dc.type.spa.fl_str_mv	Artículo de revista
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dc.identifier.doi.none.fl_str_mv	10.1080/17483107.2018.1508514
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identifier_str_mv	1748-3107 10.1080/17483107.2018.1508514
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dc.language.iso.eng.fl_str_mv	eng
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dc.relation.citationedition.spa.fl_str_mv	Disability and Rehabilitation: Assistive Technology Volume 14, 2019 - Issue 8
dc.relation.citationendpage.spa.fl_str_mv	787
dc.relation.citationstartpage.spa.fl_str_mv	776
dc.relation.citationvolume.spa.fl_str_mv	14
dc.relation.indexed.spa.fl_str_mv	N/A
dc.relation.ispartofjournal.spa.fl_str_mv	Disability and rehabilitation
dc.relation.references.eng.fl_str_mv	UN. World Population Ageing 2015. New York (NY): United Nations; 2015. WHO. Fact sheet N°404: ageing and health. Geneva: WHO; 2015 Ward BW, Schiller JS, Goodman RA. Multiple chronic conditions among US adults: a 2012 update. Prev Chronic Dis. 2014;11:130389. Elliott R. Problems with medication use in the elderly: an Australian perspective. J Pharm Prac Res. 2006;36:58–66. AidsInfor. HIV/AIDS Glossary [Internet]. 2017. Available from: https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/1641/treatment-regimen. Bartlett-Ellis R, Knisely M, Boyer K, et al. Pillbox intervention fidelity in medication adherence research: a systematic review. Nurs Outlook. 2017;65:1–13. George J, Elliott R, Stewart D. A systematic review of interventions to improve medication taking in elderly patients prescribed multiple medications. Drugs Aging. 2008;25:307–324. Haynes R, Taylor D, Sackett D. Compliance in healthcare. Baltimore (MD): John Hopkins University Press; 1979. Dezii C. Persistence with drug therapy: a practical approach using administrative claims data. Manag Care. 2001;10:42–45. Viswanathan M, Golin C, Jones C, et al. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Ann Intern Med. 2012;157:785–795. Iuga A, McGuire M. Adherence and health care costs. Risk Manag Healthc Policy. 2014;7:35–44. Hamilton GA. Measuring adherence in a hypertension clinical trial. Eur J Cardiovasc Nurs. 2003;2: 219–228. Wetzels GE, Nelemans PJ, Schouten JS, et al. All that glisters is not gold: a comparison of electronic monitoring versus filled prescriptions-an observational study. BMC Health Serv Res. 2006;6:8. Liu L, Stroulia E, Nikolaidis I, et al. Smart homes and home health monitoring technologies for older adults: a systematic review. Int J Med Inform. 2016;91:44–59. Miguel-Cruz A, Ríos-Rincón A, Rodríguez-Dueñas W, et al. What does the literature say about using robots on children with disabilities? Disabil Rehabil Assist Technol. 2017;12:429–440. Letts L, Wilkins S, Law M, et al. Guidelines for critical review form: qualitative studies (Version 2.0) [Internet]. 2007. Available from: http://srs-mcmaster.ca/wp-content/uploads/2015/05/Guidelines-for-Critical-Review-Form-Qualitative-Studies.pdf Law M, Stewart D, Pollock N, et al. Guidelines for critical review form – quantitative studies. [Internet]. 1998. Available from: http://srs-mcmaster.ca/wp-content/uploads/2015/05/Guidelines-for-Critical-Review-Form-Quantitative-Studies.pdf Portney LG, Watkins MP. Foundations of clinical research: application to practice. New Jersey (NJ): Prentice-Hall. Inc.; 2000. Cook A, Encarnação P, Adams K. Robots: assistive technologies for play, learning and cognitive development. Technol Disabil. 2010;127–145. DOE. Department of Energy Technology Readiness. Assessment guide. Washginton (DC): Office of Management. Department of Energy; 2009. Teasell R, Marshall S, Cullen N, et al. Evidence-based review of moderate to severe acquired brain injury. Executive summary. [Internet]. 2013. Available from: http://www.abiebr.com Dickersin K, Scherer R, Lefebvre C. Identifying relevant studies for systematic reviews. BMJ. 1994;309:1286–1291. Scherer P, Dickersin K, Langenberg P. Full publication of results initially presented in abstracts. A meta-analysis. JAMA. 1994;272:158–162. Light R, Pillemer D. Summing up: the science of reviewing research. Cambridge: Harvard University Press; 1984. Dickersin K, Min Y, Meinert C. Factors influencing publication of research results. JAMA. 1992;267:374–378. Kratochwill TR, Hitchcock J, Horner RH, et al. Single-case design technical documentation Version 1.0 (Pilot). [Internet]. 2010 [cited 2013 Dec 12]. Available from: http://ies.ed.gov/ncee/wwc/pdf/reference_resources/wwc_scd.pdf SCImago. SCImago journal & country rank: un nuevo portal, dos nuevos rankings. El Profesional De La Información. 2007;6:645–646. Atkin PA, Finnegan TP, Ogle SJ, et al. Functional ability of patients to manage medication packaging: a survey of geriatric inpatients. Age Ageing. 1994;23:113–116. De Bleser L, Vincke B, Dobbels F, et al. A new electronic monitoring device to measure medication adherence: usability of the helping hand™. Sensors. 2010;10:1535–1552. Boquete L, Rodriguez-Ascariz J, Artacho I, et al. Dynamically programmable electronic pill dispenser system. J Med Syst. 2010;34:357–366. Li J, Peplinski SJ, Nia SM, et al. An interoperable pillbox system for smart medication adherence. Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE; 2014; Chicago, IL. p. 1386–1389. Alvarez Cervera M, May Alvarez A, Alvarez Cervera E. Control and monitoring of medication intake Smiplus. International Conference on Electrical, Electronics, and Optimization Techniques (ICEEOT) – 2016; 2016; Chennai. Chawla S. The autonomous pill dispenser: mechanizing the delivery of tablet medication. Ubiquitous Computing, Electronics & Mobile Communication Conference (UEMCON), IEEE Annual; 2016; New York, NY. p. 1–4. Goldstein CM, Gathright EC, Dolansky MA, et al. Randomized controlled feasibility trial of two telemedicine medication reminder systems for older adults with heart failure. J Telemed Telecare. 2014;20:293–299. van Vlerken LG, Lieveld FI, van Meer S, et al. Adherence to ribavirin in chronic hepatitis C patients on antiviral treatment: results from a randomized controlled trial using real-time medication monitoring. Clin Res Hepatol Gastroenterol. 2016;40:622–630. Peterson A, Takiya L, Finley R. Meta-analysis of trials of interventions to improve medication adherence. Am J Health Syst Pharm. 2003;74:657–665. Denhaerynck K, Steiger J, Bock A, et al. Prevalence and risk factors of non-adherence with immunosuppressive medication in kidney transplant patients. Am J Transplant. 2007;7:108–116. Haynes RB, Ackloo E, Sahota N, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev. 2008;2:11. Zeller A, Schroeder K, Peters TJ. Electronic pillboxes (MEMS) to assess the relationship between medication adherence and blood pressure control in primary care. Scand J Prim Health Care. 2007;25:202–207. Chang WW, Sung TJ, Huang HW, et al. A smart medication system using wireless sensor network technologies. Sens Actuators A Phys. 2011;172:315–321. Moise N, Schwartz J, Bring R, et al. Antihypertensive drug class and adherence: an electronic monitoring study. Am J Hypertens. 2015;28:717–721. [ Touskova T, Vytrisalova M, Palicka V, et al. Patterns of non-adherence to supplementation with calcium and vitamin D in persistent postmenopausal women are similar at start and 1 year later: a Qualitative Longitudinal Study. Front Pharmacol. 2016;7:1–10. Arlt S, Lindner S, Rösler A, et al. Adherence to medication in patients with dementia. Drugs Aging. 2008;25:1033–1047. Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med. 2007;167:540. Henriksson J, Tydén G, Höijer J, et al. A prospective randomized trial on the effect of using an electronic monitoring drug dispensing device to improve adherence and compliance. Transplantation. 2016;100:203–209. Lee ML, Dey AK. Real-time feedback for improving medication taking. CHI 2014 Conference on Human Factors in Computing Systems; 2014; Toronto, ON. p. 2259–2268. Harjumaa M, Idigoras I, Isomursu M, et al. Expectations and user experience of a multimodal medicine management system for older users. Jnl of Assistive Technologies. 2014;8:51–63. Sterns AA. Curriculum design and program to train older adults to use personal digital assistants. Gerontologist. 2005;45:828–834. Reeder B, Demiris G, Marek KD. Older adults’ satisfaction with a medication dispensing device in home care. Inform Health Soc Care. 2013;38:211–222. Christensen A, Christrup LL, Fabricius P, et al. Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension. Blood Press. 2009;18:280–285. Choi J, Lim M, Kim D, et al. Proactive medication assistances based on spatiotemporal context awareness of aged persons. 30th Annual International IEEE EMBS Conference; 2008; Vancouver, BC. p. 5121–5124. Wakefield BJ, Orris LJ, Holman JE, et al. User perceptions of in-home medication dispensing devices. J Gerontol Nurs. 2008;34:15–25. Hayes TL, Hunt JM, Adami A, et al. An electronic pillbox for continuous monitoring of medication adherence. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2006. EMBS '06.; 2006; New York, NY. p. 6400–6403. Lo YL, Lee CF, Tsai WC. Electronic medication reminder for older adults. HCD'11 Proceedings of the 2nd international conference on Human centered design; 2011; Orlando, FL. p. 327–334.
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spelling	Cruz , Antonio Miguel60f912e3d0e1a88c51207ae38b105011600Aya Parra, Pedro Antonio0d01310dcf49025e774984c35568746b600Bóhorquez, Andrés Felipe2f6b7d94dfed95616d158c88873a7c78600GiBiome2021-06-03T20:28:04Z2021-10-01T17:16:58Z2021-06-032021-10-01T17:16:58Z20181748-3107https://repositorio.escuelaing.edu.co/handle/001/155410.1080/17483107.2018.1508514https://doi.org/10.1080/17483107.2018.1508514Clinical studies used commercially well-established electronic pillboxes with a high TRL. New electronic pillboxes in development had a low TRL. The discovered outcome was mainly adherence to medication. The overall mean adherence to medication regimens for all the studies using an electronic pillbox was higher than the gold standard of a good adherence level cut-off point (mean adherence 88.8%>80%). However, we found a large variation in this variable (SD = 10.7). With regard to an older adult population’s adherence to medication regimens, for the outcome variable of those who had undergone a kidney transplant, the clinical evidence that electronic pillboxes have a positive impact was strong (1b); for those with a chronic hepatitis C medical condition, the clinical evidence was medium (3), and for those with arterial hypertension and multiple chronic (diabetes and hypertension) medical conditions, the clinical evidence was weak (5).Los estudios clínicos utilizaron pastilleros electrónicos comercialmente bien establecidos con un alto TRL. Los nuevos pastilleros electrónicos en desarrollo tenían un TRL bajo. El resultado descubierto fue principalmente la adherencia a la medicación. La adherencia media general a los regímenes de medicación para todos los estudios que utilizaron un pastillero electrónico fue superior al estándar de oro de un punto de corte de buen nivel de adherencia (adherencia media del 88,8%>80%). Sin embargo, se encontró una gran variación en esta variable (SD = 10,7). Con respecto a la adherencia de la población de adultos mayores a los regímenes de medicación, para la variable de resultado de aquellos que habían sido sometidos a un trasplante de riñón, la evidencia clínica de que los pastilleros electrónicos tienen un impacto positivo fue fuerte (1b); para aquellos con una condición médica de hepatitis C crónica, la evidencia clínica fue media (3), y para aquellos con hipertensión arterial y múltiples condiciones médicas crónicas (diabetes e hipertensión), la evidencia clínica fue débil .application/pdfengInforma HealthcareColombiahttps://www.tandfonline.com/doi/abs/10.1080/17483107.2018.1508514?journalCode=iidt20What does the literature say about using electronic pillboxes for older adults? A systematic literature reviewArtículo de revistainfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85Disability and Rehabilitation: Assistive Technology Volume 14, 2019 - Issue 878777614N/ADisability and rehabilitationUN. World Population Ageing 2015. New York (NY): United Nations; 2015.WHO. Fact sheet N°404: ageing and health. Geneva: WHO; 2015Ward BW, Schiller JS, Goodman RA. Multiple chronic conditions among US adults: a 2012 update. Prev Chronic Dis. 2014;11:130389.Elliott R. Problems with medication use in the elderly: an Australian perspective. J Pharm Prac Res. 2006;36:58–66.AidsInfor. HIV/AIDS Glossary [Internet]. 2017. Available from: https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/1641/treatment-regimen.Bartlett-Ellis R, Knisely M, Boyer K, et al. Pillbox intervention fidelity in medication adherence research: a systematic review. Nurs Outlook. 2017;65:1–13.George J, Elliott R, Stewart D. A systematic review of interventions to improve medication taking in elderly patients prescribed multiple medications. Drugs Aging. 2008;25:307–324.Haynes R, Taylor D, Sackett D. Compliance in healthcare. Baltimore (MD): John Hopkins University Press; 1979.Dezii C. Persistence with drug therapy: a practical approach using administrative claims data. Manag Care. 2001;10:42–45.Viswanathan M, Golin C, Jones C, et al. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Ann Intern Med. 2012;157:785–795.Iuga A, McGuire M. Adherence and health care costs. Risk Manag Healthc Policy. 2014;7:35–44.Hamilton GA. Measuring adherence in a hypertension clinical trial. Eur J Cardiovasc Nurs. 2003;2: 219–228.Wetzels GE, Nelemans PJ, Schouten JS, et al. All that glisters is not gold: a comparison of electronic monitoring versus filled prescriptions-an observational study. BMC Health Serv Res. 2006;6:8.Liu L, Stroulia E, Nikolaidis I, et al. Smart homes and home health monitoring technologies for older adults: a systematic review. Int J Med Inform. 2016;91:44–59.Miguel-Cruz A, Ríos-Rincón A, Rodríguez-Dueñas W, et al. What does the literature say about using robots on children with disabilities? Disabil Rehabil Assist Technol. 2017;12:429–440.Letts L, Wilkins S, Law M, et al. Guidelines for critical review form: qualitative studies (Version 2.0) [Internet]. 2007. Available from: http://srs-mcmaster.ca/wp-content/uploads/2015/05/Guidelines-for-Critical-Review-Form-Qualitative-Studies.pdfLaw M, Stewart D, Pollock N, et al. Guidelines for critical review form – quantitative studies. [Internet]. 1998. Available from: http://srs-mcmaster.ca/wp-content/uploads/2015/05/Guidelines-for-Critical-Review-Form-Quantitative-Studies.pdfPortney LG, Watkins MP. Foundations of clinical research: application to practice. New Jersey (NJ): Prentice-Hall. Inc.; 2000.Cook A, Encarnação P, Adams K. Robots: assistive technologies for play, learning and cognitive development. Technol Disabil. 2010;127–145.DOE. Department of Energy Technology Readiness. Assessment guide. Washginton (DC): Office of Management. Department of Energy; 2009.Teasell R, Marshall S, Cullen N, et al. Evidence-based review of moderate to severe acquired brain injury. Executive summary. [Internet]. 2013. Available from: http://www.abiebr.comDickersin K, Scherer R, Lefebvre C. Identifying relevant studies for systematic reviews. BMJ. 1994;309:1286–1291.Scherer P, Dickersin K, Langenberg P. Full publication of results initially presented in abstracts. A meta-analysis. JAMA. 1994;272:158–162.Light R, Pillemer D. Summing up: the science of reviewing research. Cambridge: Harvard University Press; 1984.Dickersin K, Min Y, Meinert C. Factors influencing publication of research results. JAMA. 1992;267:374–378.Kratochwill TR, Hitchcock J, Horner RH, et al. Single-case design technical documentation Version 1.0 (Pilot). [Internet]. 2010 [cited 2013 Dec 12]. Available from: http://ies.ed.gov/ncee/wwc/pdf/reference_resources/wwc_scd.pdfSCImago. SCImago journal & country rank: un nuevo portal, dos nuevos rankings. El Profesional De La Información. 2007;6:645–646.Atkin PA, Finnegan TP, Ogle SJ, et al. Functional ability of patients to manage medication packaging: a survey of geriatric inpatients. Age Ageing. 1994;23:113–116.De Bleser L, Vincke B, Dobbels F, et al. A new electronic monitoring device to measure medication adherence: usability of the helping hand™. Sensors. 2010;10:1535–1552.Boquete L, Rodriguez-Ascariz J, Artacho I, et al. Dynamically programmable electronic pill dispenser system. J Med Syst. 2010;34:357–366.Li J, Peplinski SJ, Nia SM, et al. An interoperable pillbox system for smart medication adherence. Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE; 2014; Chicago, IL. p. 1386–1389.Alvarez Cervera M, May Alvarez A, Alvarez Cervera E. Control and monitoring of medication intake Smiplus. International Conference on Electrical, Electronics, and Optimization Techniques (ICEEOT) – 2016; 2016; Chennai.Chawla S. The autonomous pill dispenser: mechanizing the delivery of tablet medication. Ubiquitous Computing, Electronics & Mobile Communication Conference (UEMCON), IEEE Annual; 2016; New York, NY. p. 1–4.Goldstein CM, Gathright EC, Dolansky MA, et al. Randomized controlled feasibility trial of two telemedicine medication reminder systems for older adults with heart failure. J Telemed Telecare. 2014;20:293–299.van Vlerken LG, Lieveld FI, van Meer S, et al. Adherence to ribavirin in chronic hepatitis C patients on antiviral treatment: results from a randomized controlled trial using real-time medication monitoring. Clin Res Hepatol Gastroenterol. 2016;40:622–630.Peterson A, Takiya L, Finley R. Meta-analysis of trials of interventions to improve medication adherence. Am J Health Syst Pharm. 2003;74:657–665.Denhaerynck K, Steiger J, Bock A, et al. Prevalence and risk factors of non-adherence with immunosuppressive medication in kidney transplant patients. Am J Transplant. 2007;7:108–116.Haynes RB, Ackloo E, Sahota N, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev. 2008;2:11.Zeller A, Schroeder K, Peters TJ. Electronic pillboxes (MEMS) to assess the relationship between medication adherence and blood pressure control in primary care. Scand J Prim Health Care. 2007;25:202–207.Chang WW, Sung TJ, Huang HW, et al. A smart medication system using wireless sensor network technologies. Sens Actuators A Phys. 2011;172:315–321.Moise N, Schwartz J, Bring R, et al. Antihypertensive drug class and adherence: an electronic monitoring study. Am J Hypertens. 2015;28:717–721. [Touskova T, Vytrisalova M, Palicka V, et al. Patterns of non-adherence to supplementation with calcium and vitamin D in persistent postmenopausal women are similar at start and 1 year later: a Qualitative Longitudinal Study. Front Pharmacol. 2016;7:1–10.Arlt S, Lindner S, Rösler A, et al. Adherence to medication in patients with dementia. Drugs Aging. 2008;25:1033–1047.Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med. 2007;167:540.Henriksson J, Tydén G, Höijer J, et al. A prospective randomized trial on the effect of using an electronic monitoring drug dispensing device to improve adherence and compliance. Transplantation. 2016;100:203–209.Lee ML, Dey AK. Real-time feedback for improving medication taking. CHI 2014 Conference on Human Factors in Computing Systems; 2014; Toronto, ON. p. 2259–2268.Harjumaa M, Idigoras I, Isomursu M, et al. Expectations and user experience of a multimodal medicine management system for older users. Jnl of Assistive Technologies. 2014;8:51–63.Sterns AA. Curriculum design and program to train older adults to use personal digital assistants. Gerontologist. 2005;45:828–834.Reeder B, Demiris G, Marek KD. Older adults’ satisfaction with a medication dispensing device in home care. Inform Health Soc Care. 2013;38:211–222.Christensen A, Christrup LL, Fabricius P, et al. Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension. Blood Press. 2009;18:280–285.Choi J, Lim M, Kim D, et al. Proactive medication assistances based on spatiotemporal context awareness of aged persons. 30th Annual International IEEE EMBS Conference; 2008; Vancouver, BC. p. 5121–5124.Wakefield BJ, Orris LJ, Holman JE, et al. User perceptions of in-home medication dispensing devices. J Gerontol Nurs. 2008;34:15–25.Hayes TL, Hunt JM, Adami A, et al. An electronic pillbox for continuous monitoring of medication adherence. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2006. EMBS '06.; 2006; New York, NY. p. 6400–6403.Lo YL, Lee CF, Tsai WC. Electronic medication reminder for older adults. HCD'11 Proceedings of the 2nd international conference on Human centered design; 2011; Orlando, FL. p. 327–334.info:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbPastillero electrónicoAdultos mayoresElectronic pillboxOlder adultsCentered design approachPastillero electrónicoAdultos mayoresEnfoque de diseño centradoORIGINALWhat does the literature say about using electronic pillboxes for older adults A systematic literature review.pdfWhat does the literature say about using electronic pillboxes for older adults A systematic literature review.pdfArtículo de revistaapplication/pdf1554933https://repositorio.escuelaing.edu.co/bitstream/001/1554/6/What%20does%20the%20literature%20say%20about%20using%20electronic%20pillboxes%20for%20older%20adults%20A%20systematic%20literature%20review.pdf76775542c0ca7dd3d4d9d773d962bd5cMD56metadata only accessTHUMBNAILWhat does the literature say about using electronic pillboxes for older adults A systematic literature review.pngWhat 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What does the literature say about using electronic pillboxes for older adults? A systematic literature review

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