Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality
Connectivity between physiological networks is an issue of particular importance for understanding the complex interaction brain-heart. In the present study, this interaction was analyzed in polysomnography recordings of 28 patients diagnosed with obstructive sleep apnea (OSA) and compared with a gr...
- Autores:
-
Orjuela Cañón, Alvaro D.
Cerquera, Alexander
Freund, Jan A.
Serdá, Gabriel
Ravelo García, Antonio G.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Escuela Colombiana de Ingeniería Julio Garavito
- Repositorio:
- Repositorio Institucional ECI
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.escuelaing.edu.co:001/1489
- Acceso en línea:
- https://repositorio.escuelaing.edu.co/handle/001/1489
https://doi.org/10.1016/j.cmpb.2019.105235
- Palabra clave:
- Apnea del sueño
Neurofisiología
Sleep apnea syndromes
Neurophysiology
Continuous positive air pressure
Brain-heart network
Physiological coupling
Presión atmosférica positiva continua
Red cerebro-corazón
Acoplamiento fisiológico
- Rights
- closedAccess
- License
- http://purl.org/coar/access_right/c_14cb
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| dc.title.spa.fl_str_mv |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| title |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| spellingShingle |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality Apnea del sueño Neurofisiología Sleep apnea syndromes Neurophysiology Continuous positive air pressure Brain-heart network Physiological coupling Presión atmosférica positiva continua Red cerebro-corazón Acoplamiento fisiológico |
| title_short |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| title_full |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| title_fullStr |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| title_full_unstemmed |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| title_sort |
Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality |
| dc.creator.fl_str_mv |
Orjuela Cañón, Alvaro D. Cerquera, Alexander Freund, Jan A. Serdá, Gabriel Ravelo García, Antonio G. |
| dc.contributor.author.none.fl_str_mv |
Orjuela Cañón, Alvaro D. Cerquera, Alexander Freund, Jan A. Serdá, Gabriel Ravelo García, Antonio G. |
| dc.contributor.researchgroup.spa.fl_str_mv |
GiBiome |
| dc.subject.armarc.spa.fl_str_mv |
Apnea del sueño Neurofisiología |
| topic |
Apnea del sueño Neurofisiología Sleep apnea syndromes Neurophysiology Continuous positive air pressure Brain-heart network Physiological coupling Presión atmosférica positiva continua Red cerebro-corazón Acoplamiento fisiológico |
| dc.subject.armarc.eng.fl_str_mv |
Sleep apnea syndromes Neurophysiology |
| dc.subject.proposal.spa.fl_str_mv |
Continuous positive air pressure Brain-heart network Physiological coupling Presión atmosférica positiva continua Red cerebro-corazón Acoplamiento fisiológico |
| description |
Connectivity between physiological networks is an issue of particular importance for understanding the complex interaction brain-heart. In the present study, this interaction was analyzed in polysomnography recordings of 28 patients diagnosed with obstructive sleep apnea (OSA) and compared with a group of 10 control subjects. Electroencephalography and electrocardiography signals from these polysomnography time series were characterized employing Granger causality computation to measure the directed connectivity among five brain waves and three spectral subbands of heart rate variability. Polysomnography data from OSA patients were recorded before and during a first session of continuous positive air pressure (CPAP) therapy in a split-night study. Results showed that CPAP therapy allowed the recovery of inner brain connectivities, mainly in subsystems involving the theta wave. In addition, differences between control and OSA patients were established in connections that involve lower frequency ranges of heart rate variability. This information can be potentially useful in the initial diagnosis of OSA, and determine the role of cardiac activity in sleep dynamics based on the use of three subbands of heart rate variability. |
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2020 |
| dc.date.issued.none.fl_str_mv |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2021-05-25T23:41:33Z 2021-10-01T17:16:50Z |
| dc.date.available.none.fl_str_mv |
2021-05-25 2021-10-01T17:16:50Z |
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Artículo de revista |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Text |
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0169-2607 |
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https://repositorio.escuelaing.edu.co/handle/001/1489 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.cmpb.2019.105235 |
| dc.identifier.url.none.fl_str_mv |
https://doi.org/10.1016/j.cmpb.2019.105235 |
| identifier_str_mv |
0169-2607 10.1016/j.cmpb.2019.105235 |
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https://repositorio.escuelaing.edu.co/handle/001/1489 https://doi.org/10.1016/j.cmpb.2019.105235 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.citationedition.spa.fl_str_mv |
Computer Methods and Programs in Biomedicine : Volume 187, April 2020, 105235. |
| dc.relation.citationvolume.spa.fl_str_mv |
187 |
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N/A |
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Computer Methods and Programs in Biomedicine |
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9 páginas |
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application/pdf |
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Elsevier |
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Ireland |
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https://www.sciencedirect.com/science/article/abs/pii/S0169260719314336?via%3Dihub |
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Escuela Colombiana de Ingeniería Julio Garavito |
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Orjuela Cañón, Alvaro D.a1cbcc1bf84dc076ff7ac679a8e4a998600Cerquera, Alexander152997ffd4f1065430e5f929d67b6287600Freund, Jan A.072d182a4beb6cb15e66393110c86874600Serdá, Gabriel41414a4116722eace2c212b7cdd516be600Ravelo García, Antonio G.43b36c4e26c04d98458e1177df1c8851600GiBiome2021-05-25T23:41:33Z2021-10-01T17:16:50Z2021-05-252021-10-01T17:16:50Z20200169-2607https://repositorio.escuelaing.edu.co/handle/001/148910.1016/j.cmpb.2019.105235https://doi.org/10.1016/j.cmpb.2019.105235Connectivity between physiological networks is an issue of particular importance for understanding the complex interaction brain-heart. In the present study, this interaction was analyzed in polysomnography recordings of 28 patients diagnosed with obstructive sleep apnea (OSA) and compared with a group of 10 control subjects. Electroencephalography and electrocardiography signals from these polysomnography time series were characterized employing Granger causality computation to measure the directed connectivity among five brain waves and three spectral subbands of heart rate variability. Polysomnography data from OSA patients were recorded before and during a first session of continuous positive air pressure (CPAP) therapy in a split-night study. Results showed that CPAP therapy allowed the recovery of inner brain connectivities, mainly in subsystems involving the theta wave. In addition, differences between control and OSA patients were established in connections that involve lower frequency ranges of heart rate variability. This information can be potentially useful in the initial diagnosis of OSA, and determine the role of cardiac activity in sleep dynamics based on the use of three subbands of heart rate variability.La conectividad entre las redes fisiológicas es una cuestión de especial importancia para comprender la compleja interacción cerebro-corazón. En el presente estudio, se analizó esta interacción en grabaciones polisomnográficas de 28 pacientes diagnosticados de apnea obstructiva del sueño (AOS) y se comparó con un grupo de 10 sujetos de control. Las señales de electroencefalografía y electrocardiografía de estas series temporales de polisomnografía se caracterizaron empleando el cálculo de causalidad de Granger para medir la conectividad dirigida entre cinco ondas cerebrales y tres subbandas espectrales de la variabilidad del ritmo cardíaco. Los datos de polisomnografía de los pacientes con AOS se registraron antes y durante una primera sesión de terapia de presión de aire positiva continua (CPAP) en un estudio de dos noches. Los resultados mostraron que la terapia CPAP permitió la recuperación de las conectividades cerebrales internas, principalmente en los subsistemas que implican la onda theta. Además, se establecieron diferencias entre los pacientes de control y los de AOS en las conexiones que implican rangos de frecuencia más bajos de la variabilidad del ritmo cardíaco. Esta información puede ser potencialmente útil en el diagnóstico inicial de la AOS, y determinar el papel de la actividad cardíaca en la dinámica del sueño basándose en el uso de tres subbandas de la variabilidad de la frecuencia cardíaca© 2019 Elsevier B.V. All rights reserved.https://doi.org/10.1016/j.cmpb.2019.105235 0169-2607/© 2019 Elsevier B.V. All rights reserved.Corresponding author at: Universidad del Rosario, School of Medicine and Health Sciences. Carrera 24 No. 63C - 67. Bogotá D.C., Colombia. E-mail addresses: alvaro.orjuela@urosario.edu.co (A.D. Orjuela-Cañón), ealexander.cerqu@ufl.edu (A. Cerquera), jan.freund@uni-oldenburg.de (J.A. Freund), jjulser@gobiernodecanarias.org (G. Juliá-Serdá), antonio.ravelo@ulpgc.es (A.G. Ravelo-García).1 Both authors contributed equally to this manuscript9 páginasapplication/pdfengElsevierIrelandhttps://www.sciencedirect.com/science/article/abs/pii/S0169260719314336?via%3DihubSleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causalityArtículo de revistainfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85Computer Methods and Programs in Biomedicine : Volume 187, April 2020, 105235.187N/AComputer Methods and Programs in Biomedicineinfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbApnea del sueñoNeurofisiologíaSleep apnea syndromesNeurophysiologyContinuous positive air pressureBrain-heart networkPhysiological couplingPresión atmosférica positiva continuaRed cerebro-corazónAcoplamiento fisiológicoLICENSElicense.txttext/plain1881https://repositorio.escuelaing.edu.co/bitstream/001/1489/1/license.txt5a7ca94c2e5326ee169f979d71d0f06eMD51open accessORIGINALSleep apnea Tracking effects of a first session of CPAP therapy by.pdfapplication/pdf1019001https://repositorio.escuelaing.edu.co/bitstream/001/1489/2/Sleep%20apnea%20Tracking%20effects%20of%20a%20first%20session%20of%20CPAP%20therapy%20by.pdfced8a950128ea9e6848871f4d8af2e92MD52metadata only accessTEXTSleep apnea Tracking effects of a first session of CPAP therapy by.pdf.txtSleep apnea Tracking effects of a first session of CPAP therapy by.pdf.txtExtracted texttext/plain59294https://repositorio.escuelaing.edu.co/bitstream/001/1489/3/Sleep%20apnea%20Tracking%20effects%20of%20a%20first%20session%20of%20CPAP%20therapy%20by.pdf.txtbeed5e11ac0d764f2d9f4b0b48c365f6MD53open accessTHUMBNAILSleep apnea Tracking effects of a first session of CPAP therapy by.pdf.jpgSleep apnea Tracking effects of a first session of CPAP therapy by.pdf.jpgGenerated Thumbnailimage/jpeg15437https://repositorio.escuelaing.edu.co/bitstream/001/1489/4/Sleep%20apnea%20Tracking%20effects%20of%20a%20first%20session%20of%20CPAP%20therapy%20by.pdf.jpg6f341a1d69e9a8a72ed4eab5e77331b1MD54open access001/1489oai:repositorio.escuelaing.edu.co:001/14892022-10-06 12:56:50.383metadata only accessRepositorio Escuela Colombiana de Ingeniería Julio Garavitorepositorio.eci@escuelaing.edu.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 |