Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist.
Similar pathophysiological mechanisms within autoimmune diseases have stimulated searches for common genetic roots. Polyautoimmunity is defined as the presence of more than one autoimmune disease in a single patient. When three or more autoimmune diseases coexist, this condition is called multiple a...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2012
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/25976
- Acceso en línea:
- https://doi.org/10.1155/2012/254319
https://repository.urosario.edu.co/handle/10336/25976
- Palabra clave:
- pathophysiological mechanisms
Polyautoimmunity
autoimmune disease
- Rights
- License
- Abierto (Texto Completo)
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dc.title.spa.fl_str_mv |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
dc.title.TranslatedTitle.spa.fl_str_mv |
Introducción de la poliautoinmunidad: las enfermedades autoinmunes secundarias ya no existen. |
title |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
spellingShingle |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. pathophysiological mechanisms Polyautoimmunity autoimmune disease |
title_short |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
title_full |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
title_fullStr |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
title_full_unstemmed |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
title_sort |
Introducing polyautoimmunity: Secondary autoimmune diseases no longer exist. |
dc.subject.keyword.spa.fl_str_mv |
pathophysiological mechanisms Polyautoimmunity autoimmune disease |
topic |
pathophysiological mechanisms Polyautoimmunity autoimmune disease |
description |
Similar pathophysiological mechanisms within autoimmune diseases have stimulated searches for common genetic roots. Polyautoimmunity is defined as the presence of more than one autoimmune disease in a single patient. When three or more autoimmune diseases coexist, this condition is called multiple autoimmune syndrome (MAS). We analyzed the presence of polyautoimmunity in 1,083 patients belonging to four autoimmune disease cohorts. Polyautoimmunity was observed in 373 patients (34.4%). Autoimmune thyroid disease (AITD) and Sjogren's syndrome (SS) were the most frequent diseases encountered. Factors significantly associated with polyautoimmunity were female gender and familial autoimmunity. Through a systematic literature review, an updated search was done for all MAS cases (January 2006-September 2011). There were 142 articles retrieved corresponding to 226 cases. Next, we performed a clustering analysis in which AITD followed by systemic lupus erythematosus and SS were the most hierarchical diseases encountered. Our results indicate that coexistence of autoimmune diseases is not uncommon and follows a grouping pattern. Polyautoimmunity is the term proposed for this association of disorders, which encompasses the concept of a common origin for these diseases. |
publishDate |
2012 |
dc.date.created.spa.fl_str_mv |
2012 |
dc.date.accessioned.none.fl_str_mv |
2020-08-06T16:20:22Z |
dc.date.available.none.fl_str_mv |
2020-08-06T16:20:22Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1155/2012/254319 |
dc.identifier.issn.none.fl_str_mv |
ISSN: 20900422 EISSN: 2090-0430 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/25976 |
url |
https://doi.org/10.1155/2012/254319 https://repository.urosario.edu.co/handle/10336/25976 |
identifier_str_mv |
ISSN: 20900422 EISSN: 2090-0430 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
319 |
dc.relation.citationStartPage.none.fl_str_mv |
254 |
dc.relation.citationTitle.none.fl_str_mv |
Autoimmune diseases |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 2012 |
dc.relation.ispartof.spa.fl_str_mv |
Autoimmune diseases, ISSN: 20900422 ; EISSN: 2090-0430, Vol.2012 (2012); pp.254-319 |
dc.relation.uri.spa.fl_str_mv |
http://downloads.hindawi.com/journals/ad/2012/254319.pdf |
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http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
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Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
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application/pdf |
dc.publisher.spa.fl_str_mv |
Hindawi Publishing Corporation |
dc.source.spa.fl_str_mv |
Autoimmune diseases |
institution |
Universidad del Rosario |
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instname:Universidad del Rosario |
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reponame:Repositorio Institucional EdocUR |
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