High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia

Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2016
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/27802
Acceso en línea:
https://doi.org/10.1093/infdis/jiw360
https://repository.urosario.edu.co/handle/10336/27802
Palabra clave:
Chagas disease
Oral transmission
Outbreaks
Triatomines
Trypanosoma cruzi
Opossums
Canines
Food
Rights
License
Abierto (Texto Completo)
id EDOCUR2_fcc7336cfd96fa7c24c5a296165a0874
oai_identifier_str oai:repository.urosario.edu.co:10336/27802
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 520857956006b66781c-3f2e-48b7-ac16-00930a0b462e180780cc-4c03-4eef-bdea-5f111ebe20ec1ba4f510-30ed-403d-b3df-d6d598932a1d10117161186002020-08-19T14:43:58Z2020-08-19T14:43:58Z2016-08-10Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.application/pdfhttps://doi.org/10.1093/infdis/jiw360ISSN: 0022-1899EISSN: 1537-6613https://repository.urosario.edu.co/handle/10336/27802engInfectious Diseases Society of AmericaOxford University Press1255No. 81252Journal of Infectious DiseasesVol. 214Journal of Infectious Diseases, ISSN: 0022-1899;EISSN: 1537-6613, Vol.214, No.8 (15 October 2016); pp. 1252–1255https://watermark.silverchair.com/jiw360.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAqkwggKlBgkqhkiG9w0BBwagggKWMIICkgIBADCCAosGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMSWzcWkuaFjApc3PQAgEQgIICXEYFyL2ww77yKQAywwgTuq5hxkYgJwgmEB9ApYrTIrVdiMuXyNeYM2fuRbvw-oMCqvjBgIgGodAkKWKG_LyiPrl54HwHuBdk8JgwE-bmFgeySrdzsrmmFr2aAYIsEniUaqY17dEBI3PoMD9Ai2JHfERL-Xz5kHOslCQL_JUQ8PPzNV7OlDc6ZV1min8UlWuW53yQaXNkmXb9qjxJwoIb0gjvOfP7J_NAnb7DhMB5D6geemktOeGEKnjWk86uItMbPYgtPaLQHELSJ0XvYF7JS-dzWNJvpIhz8ydpyrY9X4qju9ojWK6PmRpKcCRhhIDEa3sBegSu3BXX41L-tO1maDy_7X_hL1xSumFPwM11BzsPel0AwrgIqDP2zZiuSenWGmaokm2zHEeJ1Ss2r1HXWO3uBSKt8MxyMgFn-HPNtColVozviHbxoMdcPeD7VqPFR8jVgezwPqEs3OV3q2Zgjc8rbxov3aw5awHMXm601-5SL41JUYV5TvLCJHkdfz6mn31KB0Ewcd5977NTk283qKNiPTkY_518Ec1A99IBl2KARdjnkZhJmqfPFH-XaTaQB0anobqe5pDg43nPsW2fOiSFiEaYO9nRMWUMY3I0-v-4LbQmWlSahyznPqqaLef6pzE3ccvhW6mGU1_Dz3XTfAe0T5KS6oPrJbID0KTQPnlpFOHSn7V46aReKKyF77Mlj52Mm3KCBR8Eulr0l6jm1NAhAsxwj6k_-sW7KgoxyQmKa3na1fDtoXedpnTEZ-zGeQgIpUjOLNe1MIfHS2eNgTrEw5Z3YZQRknU0dBEAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Journal of Infectious Diseasesinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURChagas diseaseOral transmissionOutbreaksTriatominesTrypanosoma cruziOpossumsCaninesFoodHigh-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in ColombiaTipificación molecular de alta resolución de tripanosoma cruzi en 2 grandes brotes de enfermedad de chagas aguda en ColombiaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Galindo Hernández, CarolinaVera, Mauricio JavierCucunubá, ZulmaFlórez, CarolinaRamírez, Juan DavidORIGINALjiw360.pdfapplication/pdf376341https://repository.urosario.edu.co/bitstreams/9c192077-27c3-41d4-8b11-c4a6dac85449/downloadd96a0210ea3d8a105eb2935fb9127e00MD51TEXTjiw360.pdf.txtjiw360.pdf.txtExtracted texttext/plain22078https://repository.urosario.edu.co/bitstreams/d90181b1-c260-4ceb-8dc9-b0c853227243/download36c7cde50f0bb84ccbedb3d4f85ec162MD52THUMBNAILjiw360.pdf.jpgjiw360.pdf.jpgGenerated Thumbnailimage/jpeg5194https://repository.urosario.edu.co/bitstreams/30b47755-9ed2-496f-a77d-bc9abaea50ca/download9db312fef383aadb4a6871ccf8ce5c6aMD5310336/27802oai:repository.urosario.edu.co:10336/278022021-10-05 06:51:53.514https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
dc.title.TranslatedTitle.spa.fl_str_mv Tipificación molecular de alta resolución de tripanosoma cruzi en 2 grandes brotes de enfermedad de chagas aguda en Colombia
title High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
spellingShingle High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
Chagas disease
Oral transmission
Outbreaks
Triatomines
Trypanosoma cruzi
Opossums
Canines
Food
title_short High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
title_full High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
title_fullStr High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
title_full_unstemmed High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
title_sort High-resolution molecular typing of trypanosoma cruzi in 2 large outbreaks of acute chagas disease in Colombia
dc.subject.keyword.spa.fl_str_mv Chagas disease
Oral transmission
Outbreaks
Triatomines
Trypanosoma cruzi
Opossums
Canines
Food
topic Chagas disease
Oral transmission
Outbreaks
Triatomines
Trypanosoma cruzi
Opossums
Canines
Food
description Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.
publishDate 2016
dc.date.created.spa.fl_str_mv 2016-08-10
dc.date.accessioned.none.fl_str_mv 2020-08-19T14:43:58Z
dc.date.available.none.fl_str_mv 2020-08-19T14:43:58Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1093/infdis/jiw360
dc.identifier.issn.none.fl_str_mv ISSN: 0022-1899
EISSN: 1537-6613
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/27802
url https://doi.org/10.1093/infdis/jiw360
https://repository.urosario.edu.co/handle/10336/27802
identifier_str_mv ISSN: 0022-1899
EISSN: 1537-6613
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 1255
dc.relation.citationIssue.none.fl_str_mv No. 8
dc.relation.citationStartPage.none.fl_str_mv 1252
dc.relation.citationTitle.none.fl_str_mv Journal of Infectious Diseases
dc.relation.citationVolume.none.fl_str_mv Vol. 214
dc.relation.ispartof.spa.fl_str_mv Journal of Infectious Diseases, ISSN: 0022-1899;EISSN: 1537-6613, Vol.214, No.8 (15 October 2016); pp. 1252–1255
dc.relation.uri.spa.fl_str_mv https://watermark.silverchair.com/jiw360.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAqkwggKlBgkqhkiG9w0BBwagggKWMIICkgIBADCCAosGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMSWzcWkuaFjApc3PQAgEQgIICXEYFyL2ww77yKQAywwgTuq5hxkYgJwgmEB9ApYrTIrVdiMuXyNeYM2fuRbvw-oMCqvjBgIgGodAkKWKG_LyiPrl54HwHuBdk8JgwE-bmFgeySrdzsrmmFr2aAYIsEniUaqY17dEBI3PoMD9Ai2JHfERL-Xz5kHOslCQL_JUQ8PPzNV7OlDc6ZV1min8UlWuW53yQaXNkmXb9qjxJwoIb0gjvOfP7J_NAnb7DhMB5D6geemktOeGEKnjWk86uItMbPYgtPaLQHELSJ0XvYF7JS-dzWNJvpIhz8ydpyrY9X4qju9ojWK6PmRpKcCRhhIDEa3sBegSu3BXX41L-tO1maDy_7X_hL1xSumFPwM11BzsPel0AwrgIqDP2zZiuSenWGmaokm2zHEeJ1Ss2r1HXWO3uBSKt8MxyMgFn-HPNtColVozviHbxoMdcPeD7VqPFR8jVgezwPqEs3OV3q2Zgjc8rbxov3aw5awHMXm601-5SL41JUYV5TvLCJHkdfz6mn31KB0Ewcd5977NTk283qKNiPTkY_518Ec1A99IBl2KARdjnkZhJmqfPFH-XaTaQB0anobqe5pDg43nPsW2fOiSFiEaYO9nRMWUMY3I0-v-4LbQmWlSahyznPqqaLef6pzE3ccvhW6mGU1_Dz3XTfAe0T5KS6oPrJbID0KTQPnlpFOHSn7V46aReKKyF77Mlj52Mm3KCBR8Eulr0l6jm1NAhAsxwj6k_-sW7KgoxyQmKa3na1fDtoXedpnTEZ-zGeQgIpUjOLNe1MIfHS2eNgTrEw5Z3YZQRknU0dBE
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Infectious Diseases Society of America
Oxford University Press
dc.source.spa.fl_str_mv Journal of Infectious Diseases
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
bitstream.url.fl_str_mv https://repository.urosario.edu.co/bitstreams/9c192077-27c3-41d4-8b11-c4a6dac85449/download
https://repository.urosario.edu.co/bitstreams/d90181b1-c260-4ceb-8dc9-b0c853227243/download
https://repository.urosario.edu.co/bitstreams/30b47755-9ed2-496f-a77d-bc9abaea50ca/download
bitstream.checksum.fl_str_mv d96a0210ea3d8a105eb2935fb9127e00
36c7cde50f0bb84ccbedb3d4f85ec162
9db312fef383aadb4a6871ccf8ce5c6a
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
_version_ 1814167704081268736