Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru
Introduction: Urinary tract infections (UTIs) are the second most frequent reason for healthcare visits, and antibiotic resistance among gram-negative bacteria of the Enterobacteriaceae family has increased significantly worldwide. The emergence of microorganisms that produce extended-spectrum beta-...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2020
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
spa
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/29533
- Acceso en línea:
- https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.9255
https://repository.urosario.edu.co/handle/10336/29533
- Palabra clave:
- Infección del tracto urinario
Resistencia antibiótica
Bacteriología
betalactamase
Infeção do trato urinário
Resistência antibiótica
Urinary tract infection
Beta-lactamase
Antibiotic resistance
Bacteriology
- Rights
- License
- Abierto (Texto Completo)
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Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| dc.title.TranslatedTitle.spa.fl_str_mv |
Factores asociados con la presencia de patógenos productores de betalactamasas de espectro extendido en infecciones urinarias en una clínica privada, Lima (Perú) |
| dc.title.TranslatedTitle.por.fl_str_mv |
Fatores associados à presença de patógenos produtores de betalactamases de espectro estendido em infeções urinárias em uma clínica privada, Lima (Peru) |
| title |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| spellingShingle |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru Infección del tracto urinario Resistencia antibiótica Bacteriología betalactamase Infeção do trato urinário Resistência antibiótica Urinary tract infection Beta-lactamase Antibiotic resistance Bacteriology |
| title_short |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| title_full |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| title_fullStr |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| title_full_unstemmed |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| title_sort |
Factors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, Peru |
| dc.subject.spa.fl_str_mv |
Infección del tracto urinario Resistencia antibiótica Bacteriología betalactamase |
| topic |
Infección del tracto urinario Resistencia antibiótica Bacteriología betalactamase Infeção do trato urinário Resistência antibiótica Urinary tract infection Beta-lactamase Antibiotic resistance Bacteriology |
| dc.subject.keyword.por.fl_str_mv |
Infeção do trato urinário Resistência antibiótica |
| dc.subject.keyword.eng.fl_str_mv |
Urinary tract infection Beta-lactamase Antibiotic resistance Bacteriology |
| description |
Introduction: Urinary tract infections (UTIs) are the second most frequent reason for healthcare visits, and antibiotic resistance among gram-negative bacteria of the Enterobacteriaceae family has increased significantly worldwide. The emergence of microorganisms that produce extended-spectrum beta-lactamase (ESBL) is especially problematic. This study aims to identify factors associated with the presence of UTI caused by ESBL-producing pathogens. Material and methods: An analytical cross-sectional study was conducted, and the urine culture database from a private healthcare clinic was analyzed. Factors possibly associated with the appearance of UTIs due to ESBL-producing pathogens were analyzed, including sex, age, number of hospitalizations, and previous UTIs. Results: A total of 1405 positive urine cultures were studied, 85.48% of which belonged to women. The mean age of the subjects was 39.98 ± 24.51 years, 24.13% of whom were over 60 years old. Of these, 55.56% had been attended on an outpatient basis. Almost half (49.18%) of the cultures tested positive for ESBL-related UTI, 96.58% of which had not presented with a previous UTI. A statistically significant association was found between sex and the development of UTI caused by ESBL-producing microorganisms (p = 0.007), with the male sex having the highest association (prevalence ratio, 1.224; 95% confidence interval: 1.035-1.448). In addition, age, number of previous hospitalizations, and prior intensive care unit admissions also showed associations with UTI development. No association was found with the presence of previous UTIs. Conclusion: A high frequency of UTIs were ESBL-related, and the factors associated with ESBL-related UTIs were male sex, age >60, and previous hospitalizations. |
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2020 |
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2020-09-09T15:38:52Z |
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2020-09-09T15:38:52Z |
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2020-06-19 |
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article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_6501 |
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Artículo |
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https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.9255 |
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2145-4507 1692-7273 |
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https://repository.urosario.edu.co/handle/10336/29533 |
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https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.9255 https://repository.urosario.edu.co/handle/10336/29533 |
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2145-4507 1692-7273 |
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eng spa |
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eng spa |
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11 |
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No. 2 |
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1 |
| dc.relation.citationTitle.none.fl_str_mv |
Revista Ciencias de la Salud |
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Vol. 18 |
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Revista Ciencias de la Salud; Vol. 18 No. 2 (2020); 1-11 |
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Revista Ciencias de la Salud; Vol. 18 Núm. 2 (2020); 1-11 |
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Revista Ciencias de la Salud; v. 18 n. 2 (2020); 1-11 |
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https://revistas.urosario.edu.co/index.php/revsalud/article/view/9255 |
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Abierto (Texto Completo) |
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Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
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application/pdf |
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Universidad del Rosario |
| dc.publisher.department.none.fl_str_mv |
Escuela de Medicina y Ciencias de la Salud |
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Revista Ciencias de la Salud |
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Universidad del Rosario |
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reponame:Repositorio Institucional EdocUR |
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15a689bd-89d7-425e-b79c-3fde538e262b565c9c65-f1b0-4f4e-aa8e-872e12dbf0125de8ba68-b2dc-43ad-b2a3-b30d00d08dee2020-09-09T15:38:52Z2020-09-09T15:38:52Z2020-06-19Introduction: Urinary tract infections (UTIs) are the second most frequent reason for healthcare visits, and antibiotic resistance among gram-negative bacteria of the Enterobacteriaceae family has increased significantly worldwide. The emergence of microorganisms that produce extended-spectrum beta-lactamase (ESBL) is especially problematic. This study aims to identify factors associated with the presence of UTI caused by ESBL-producing pathogens. Material and methods: An analytical cross-sectional study was conducted, and the urine culture database from a private healthcare clinic was analyzed. Factors possibly associated with the appearance of UTIs due to ESBL-producing pathogens were analyzed, including sex, age, number of hospitalizations, and previous UTIs. Results: A total of 1405 positive urine cultures were studied, 85.48% of which belonged to women. The mean age of the subjects was 39.98 ± 24.51 years, 24.13% of whom were over 60 years old. Of these, 55.56% had been attended on an outpatient basis. Almost half (49.18%) of the cultures tested positive for ESBL-related UTI, 96.58% of which had not presented with a previous UTI. A statistically significant association was found between sex and the development of UTI caused by ESBL-producing microorganisms (p = 0.007), with the male sex having the highest association (prevalence ratio, 1.224; 95% confidence interval: 1.035-1.448). In addition, age, number of previous hospitalizations, and prior intensive care unit admissions also showed associations with UTI development. No association was found with the presence of previous UTIs. Conclusion: A high frequency of UTIs were ESBL-related, and the factors associated with ESBL-related UTIs were male sex, age >60, and previous hospitalizations.Introducción: las infecciones del tracto urinario (ITU) son el segundo motivo más frecuente de atención médica, y la resistencia a los antibióticos entre las enterobacterias gramnegativas ha aumentado de manera importante en todo el mundo, dada la aparición de organismos productores de betalactamasa de espectro extendido (BLEE). Se busca identificar factores asociados a la presencia de ITU por patógeno productor de BLEE. Materiales y métodos: se realizó un estudio trasversal analítico, un análisis de la base de datos de urocultivos de una clínica privada y una evaluación de los factores posiblemente asociados a la presentación de ITU por el microorganismo BLEE, como el sexo, la edad, el número de hospitalizaciones e ITU previas. Resultados: se estudiaron 1405 urocultivos positivos y se encontró que el 85.48 % fueron de sexo femenino. La edad media de la población fue de 39.98 ± 24.51 años, el 24.13 % de edad mayor a 60 años, y el 55.56 % habían sido atendidos ambulatoriamente. El 49.18 % de los cultivos fue positivo para ITU BLEE, de los cuales el 96,58 % no habían presentado una ITU previa. Se encontró que existe una asociación estadísticamente significativa (0,007; p ? 0,05) entre el sexo y el desarrollo de ITU por microorganismo productor de BLEE. El masculino es el de mayor asociación (OR 1,224; IC95 %: 1,035-1,448). También se encontró una asociación con la edad, el número de hospitalizaciones previas y haber estado en UCI. No se encontró ninguna asociación entre la presencia de ITU previas. Conclusiones: existe una elevada frecuencia de ITU BLEE, y los factores asociados a dicha infección fueron tener sexo masculino, una edad mayor a 60 años y hospitalizaciones previas.Introdução: as infeções do trato urinário (ITU) são o segundo motivo mais frequente de atenção médica e a resistência aos antibióticos entre as enterobactérias gramnegativas tem aumentado de maneira importante no mundo todo; destacado pela aparição de organismos produtores de betalactamase de espectro estendido (BLEE). Busca-se identificar fatores associados à presença de ITU por patógeno produtor de BLEE. Materiais e métodos: se realizou estudo transversal analítico, analisando a base de dados de urocultura de uma clínica privada, avaliando fatores possivelmente associados à apresentação de ITU por microrganismo BLEE, como o sexo, a idade, o número de hospitalizações e ITU prévias. Resultados: estudaram-se 1405 uroculturas positivas, encontrado que o 85,48% foram de sexo feminino. A idade média da população foi de 39.98±24.51 anos, 24.13% de idade maior a 60 anos, 55.56% tinham sido atendidos ambulatoriamente. O 49.18% dos cultivos foi positivo para ITU BLEE, dos quais 96.58% não tinham apresentado uma ITU prévia. Se encontrou que existe associação estatisticamente significativa (0.007; p ≤ 0.05) entre o sexo e o desenvolvimento de ITU por microrganismo produtor de BLEE, sendo o masculino o de maior associação (OR 1,224; IC 95%: 1,035-1,448). Além disso, tanto a idade quanto o número de hospitalizações prévias, e ter estado em UCI também mostraram associação. Não se encontrou associação entre a presença de ITU prévias. Conclusões: existe uma elevada frequência de ITU BLEE e os fatores associados a infeção por ITU BLEE foram o sexo masculino, idade > 60 anos e hospitalização prévias.application/pdfhttps://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.92552145-45071692-7273https://repository.urosario.edu.co/handle/10336/29533engspaUniversidad del RosarioEscuela de Medicina y Ciencias de la Salud11No. 21Revista Ciencias de la SaludVol. 18Revista Ciencias de la Salud; Vol. 18 No. 2 (2020); 1-11Revista Ciencias de la Salud; Vol. 18 Núm. 2 (2020); 1-11Revista Ciencias de la Salud; v. 18 n. 2 (2020); 1-11https://revistas.urosario.edu.co/index.php/revsalud/article/view/9255Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Revista Ciencias de la Saludinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURInfección del tracto urinarioResistencia antibióticaBacteriologíabetalactamaseInfeção do trato urinárioResistência antibióticaUrinary tract infectionBeta-lactamaseAntibiotic resistanceBacteriologyFactors Associated with the Presence of Extended-Spectrum Beta-Lactamase-Producing Pathogens in Urinary Tract Infections in a Private Clinic in Lima, PeruFactores asociados con la presencia de patógenos productores de betalactamasas de espectro extendido en infecciones urinarias en una clínica privada, Lima (Perú)Fatores associados à presença de patógenos produtores de betalactamases de espectro estendido em infeções urinárias em uma clínica privada, Lima (Peru)articleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Remenik-Zarauz, VaniaDiaz-Velez, CristianApolaya-Segura, MoisésORIGINALFactores-asociados-con-la-presencia.pdfFactores-asociados-con-la-presencia.pdfapplication/pdf256746https://repository.urosario.edu.co/bitstreams/7e0075b0-b750-4d9c-a16f-08837e306542/download6799ad444d5dde3b971a8de71513a135MD51TEXTFactores-asociados-con-la-presencia.pdf.txtFactores-asociados-con-la-presencia.pdf.txtExtracted texttext/plain28873https://repository.urosario.edu.co/bitstreams/063e7615-9db3-4959-9fe9-8159dbd6a2fb/downloadf5609ba566c95a1e20f6cae9900b5769MD52THUMBNAILFactores-asociados-con-la-presencia.pdf.jpgFactores-asociados-con-la-presencia.pdf.jpgGenerated Thumbnailimage/jpeg4168https://repository.urosario.edu.co/bitstreams/ed5595d2-7399-4620-b1ca-b8dd3844e2d6/download5a0f4aafdaefb0371a6e3c9c7bd83bc6MD5310336/29533oai:repository.urosario.edu.co:10336/295332022-08-24 11:20:21.238269https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |