Polyautoimmunity in Sjögren Syndrome

Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern. The most frequent ADs observed in SS are autoimmune thyroid disease, rheumatoid arthritis, and systemic lupus erythematosus. Main factors associated with polyautoimmunity in SS are tobacco smoking and some genetic variants. The study of polyautoimmunity provides important clues for elucidating the common mechanisms of autoimmne diseases (ie, the autoimmune tautology). © 2016 Elsevier Inc.

• Fecha de publicación: 2016
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/23248
• Acceso en línea: https://doi.org/10.1016/j.rdc.2016.03.005; https://repository.urosario.edu.co/handle/10336/23248
• Palabra clave: Rituximab; Antibody specificity; Autoimmune disease; Autoimmune hepatitis; Autoimmunity; Disease association; Disease course; Disease severity; Genetic variability; Human; Immunopathogenesis; Polyautoimmunity; Priority journal; Review; Rheumatoid arthritis; Risk assessment; Risk factor; Sjoegren syndrome; Smoking; Symptom; Systemic disease; Systemic lupus erythematosus; Systemic sclerosis; Thyroid disease; Autoimmune diseases; Autoimmunity; Comorbidity; Genetics; Immunology; Sjogren's syndrome; Autoimmune diseases; Autoimmunity; Comorbidity; Humans; Sjogren's syndrome; Smoking; Autoimmune tautology; Polyautoimmunity; Sjögren syndrome; autoimmune; rheumatoid; systemic; rheumatoid; systemic; autoimmune; Arthritis; Lupus erythematosus; Thyroiditis; Arthritis; Lupus erythematosus; Thyroiditis
• License: Abierto (Texto Completo)