From endothelial dysfunction to arterial stiffness in diabetes mellitus

Prevalence of diabetes mellitus has increased drastically over time, especially in more populous countries such as the United States, India, and China. Patients with diabetes have an increased risk of major cardiovascular events such as acute myocardial infarction, cerebrovascular dis-ease, and peri...

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Tipo de recurso:
Fecha de publicación:
2020
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23800
Acceso en línea:
https://doi.org/10.2174/1573399814666181017120415
https://repository.urosario.edu.co/handle/10336/23800
Palabra clave:
Arterial stiffness
Article
Atherosclerosis
Atherosclerotic plaque
Cardiovascular risk
Diabetes mellitus
Diabetic patient
Endothelial dysfunction
Glucose blood level
Human
Impaired glucose tolerance
Inflammation
Insulin dependent diabetes mellitus
Microalbuminuria
Mortality
Non insulin dependent diabetes mellitus
Oxidative stress
Pathophysiology
Predictive value
Priority journal
Protein glycosylation
Thrombocyte function
Vascular disease
Arterial stiffness
Diabetes mellitus
Diabetic angiopathy
Disease exacerbation
Pathophysiology
Physiology
Risk factor
Vascular endothelium
Diabetes mellitus
Diabetic angiopathies
Disease progression
Humans
Risk factors
Vascular stiffness
Coronary heart disease
Diabetes mellitus
Diabetic angiopathies
Diabetic neuropathies
Diabetic retinopathy
Vascular stiffness
vascular
Endothelium
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Abierto (Texto Completo)
id EDOCUR2_f4caf9fbb1aa68cf1ecb1a696cda043e
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spelling 66bdfb26-b496-4c8c-92fb-7ccb9b928429-189e8bb91-9671-4fd7-873c-0426fc673e68-12020-05-26T00:05:30Z2020-05-26T00:05:30Z2020Prevalence of diabetes mellitus has increased drastically over time, especially in more populous countries such as the United States, India, and China. Patients with diabetes have an increased risk of major cardiovascular events such as acute myocardial infarction, cerebrovascular dis-ease, and peripheral vascular disease. Arterial stiffness is a process related to aging and vascular, metabolic, cellular and physiological deterioration. In recent years, it has been described as an independent predictor of cardiovascular mortality and coronary artery disease. Additionally, it plays an important role in the measurement of chronic disease progression. Recent studies have suggested a strong relationship between diabetes mellitus and arterial stiffness since they share a similar pathophysiology involving endothelial dysfunction. The literature has shown that microvascular and mac-rovascular complications in diabetic patients could be screened and measured with arterial stiffness. Additionally, new evidence proposes that there is a relationship between blood glucose levels, micro-albuminuria, and arterial stiffness. Moreover, arterial stiffness predicts cardiovascular risk and is in-dependently associated with mortality in diabetic patients. Abnormal arterial stiffness values in diabetic patients should alert the clinician to the presence of vascular disease, which merits early study and treatment. We await more studies to determine if arterial stiffness could be considered a routine useful non-invasive tool in the evaluation of diabetic patients. There is enough evidence to conclude that arterial stiffness is related to the progression of diabetes mellitus. © 2020 Bentham Science Publishers.application/pdfhttps://doi.org/10.2174/157339981466618101712041515733998https://repository.urosario.edu.co/handle/10336/23800engBentham Science Publishers237No. 3230Current Diabetes ReviewsVol. 16Current Diabetes Reviews, ISSN:15733998, Vol.16, No.3 (2020); pp. 230-237https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082492629&doi=10.2174%2f1573399814666181017120415&partnerID=40&md5=c0022b5846dc14162a4f07a0d52fede6Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURArterial stiffnessArticleAtherosclerosisAtherosclerotic plaqueCardiovascular riskDiabetes mellitusDiabetic patientEndothelial dysfunctionGlucose blood levelHumanImpaired glucose toleranceInflammationInsulin dependent diabetes mellitusMicroalbuminuriaMortalityNon insulin dependent diabetes mellitusOxidative stressPathophysiologyPredictive valuePriority journalProtein glycosylationThrombocyte functionVascular diseaseArterial stiffnessDiabetes mellitusDiabetic angiopathyDisease exacerbationPathophysiologyPhysiologyRisk factorVascular endotheliumDiabetes mellitusDiabetic angiopathiesDisease progressionHumansRisk factorsVascular stiffnessCoronary heart diseaseDiabetes mellitusDiabetic angiopathiesDiabetic neuropathiesDiabetic retinopathyVascular stiffnessvascularEndotheliumFrom endothelial dysfunction to arterial stiffness in diabetes mellitusarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Giraldo-Grueso, ManuelEcheverri, Darío10336/23800oai:repository.urosario.edu.co:10336/238002022-05-02 07:37:21.213699https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv From endothelial dysfunction to arterial stiffness in diabetes mellitus
title From endothelial dysfunction to arterial stiffness in diabetes mellitus
spellingShingle From endothelial dysfunction to arterial stiffness in diabetes mellitus
Arterial stiffness
Article
Atherosclerosis
Atherosclerotic plaque
Cardiovascular risk
Diabetes mellitus
Diabetic patient
Endothelial dysfunction
Glucose blood level
Human
Impaired glucose tolerance
Inflammation
Insulin dependent diabetes mellitus
Microalbuminuria
Mortality
Non insulin dependent diabetes mellitus
Oxidative stress
Pathophysiology
Predictive value
Priority journal
Protein glycosylation
Thrombocyte function
Vascular disease
Arterial stiffness
Diabetes mellitus
Diabetic angiopathy
Disease exacerbation
Pathophysiology
Physiology
Risk factor
Vascular endothelium
Diabetes mellitus
Diabetic angiopathies
Disease progression
Humans
Risk factors
Vascular stiffness
Coronary heart disease
Diabetes mellitus
Diabetic angiopathies
Diabetic neuropathies
Diabetic retinopathy
Vascular stiffness
vascular
Endothelium
title_short From endothelial dysfunction to arterial stiffness in diabetes mellitus
title_full From endothelial dysfunction to arterial stiffness in diabetes mellitus
title_fullStr From endothelial dysfunction to arterial stiffness in diabetes mellitus
title_full_unstemmed From endothelial dysfunction to arterial stiffness in diabetes mellitus
title_sort From endothelial dysfunction to arterial stiffness in diabetes mellitus
dc.subject.keyword.spa.fl_str_mv Arterial stiffness
Article
Atherosclerosis
Atherosclerotic plaque
Cardiovascular risk
Diabetes mellitus
Diabetic patient
Endothelial dysfunction
Glucose blood level
Human
Impaired glucose tolerance
Inflammation
Insulin dependent diabetes mellitus
Microalbuminuria
Mortality
Non insulin dependent diabetes mellitus
Oxidative stress
Pathophysiology
Predictive value
Priority journal
Protein glycosylation
Thrombocyte function
Vascular disease
Arterial stiffness
Diabetes mellitus
Diabetic angiopathy
Disease exacerbation
Pathophysiology
Physiology
Risk factor
Vascular endothelium
Diabetes mellitus
Diabetic angiopathies
Disease progression
Humans
Risk factors
Vascular stiffness
Coronary heart disease
Diabetes mellitus
Diabetic angiopathies
Diabetic neuropathies
Diabetic retinopathy
Vascular stiffness
topic Arterial stiffness
Article
Atherosclerosis
Atherosclerotic plaque
Cardiovascular risk
Diabetes mellitus
Diabetic patient
Endothelial dysfunction
Glucose blood level
Human
Impaired glucose tolerance
Inflammation
Insulin dependent diabetes mellitus
Microalbuminuria
Mortality
Non insulin dependent diabetes mellitus
Oxidative stress
Pathophysiology
Predictive value
Priority journal
Protein glycosylation
Thrombocyte function
Vascular disease
Arterial stiffness
Diabetes mellitus
Diabetic angiopathy
Disease exacerbation
Pathophysiology
Physiology
Risk factor
Vascular endothelium
Diabetes mellitus
Diabetic angiopathies
Disease progression
Humans
Risk factors
Vascular stiffness
Coronary heart disease
Diabetes mellitus
Diabetic angiopathies
Diabetic neuropathies
Diabetic retinopathy
Vascular stiffness
vascular
Endothelium
dc.subject.keyword.eng.fl_str_mv vascular
Endothelium
description Prevalence of diabetes mellitus has increased drastically over time, especially in more populous countries such as the United States, India, and China. Patients with diabetes have an increased risk of major cardiovascular events such as acute myocardial infarction, cerebrovascular dis-ease, and peripheral vascular disease. Arterial stiffness is a process related to aging and vascular, metabolic, cellular and physiological deterioration. In recent years, it has been described as an independent predictor of cardiovascular mortality and coronary artery disease. Additionally, it plays an important role in the measurement of chronic disease progression. Recent studies have suggested a strong relationship between diabetes mellitus and arterial stiffness since they share a similar pathophysiology involving endothelial dysfunction. The literature has shown that microvascular and mac-rovascular complications in diabetic patients could be screened and measured with arterial stiffness. Additionally, new evidence proposes that there is a relationship between blood glucose levels, micro-albuminuria, and arterial stiffness. Moreover, arterial stiffness predicts cardiovascular risk and is in-dependently associated with mortality in diabetic patients. Abnormal arterial stiffness values in diabetic patients should alert the clinician to the presence of vascular disease, which merits early study and treatment. We await more studies to determine if arterial stiffness could be considered a routine useful non-invasive tool in the evaluation of diabetic patients. There is enough evidence to conclude that arterial stiffness is related to the progression of diabetes mellitus. © 2020 Bentham Science Publishers.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:05:30Z
dc.date.available.none.fl_str_mv 2020-05-26T00:05:30Z
dc.date.created.spa.fl_str_mv 2020
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.2174/1573399814666181017120415
dc.identifier.issn.none.fl_str_mv 15733998
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/23800
url https://doi.org/10.2174/1573399814666181017120415
https://repository.urosario.edu.co/handle/10336/23800
identifier_str_mv 15733998
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 237
dc.relation.citationIssue.none.fl_str_mv No. 3
dc.relation.citationStartPage.none.fl_str_mv 230
dc.relation.citationTitle.none.fl_str_mv Current Diabetes Reviews
dc.relation.citationVolume.none.fl_str_mv Vol. 16
dc.relation.ispartof.spa.fl_str_mv Current Diabetes Reviews, ISSN:15733998, Vol.16, No.3 (2020); pp. 230-237
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082492629&doi=10.2174%2f1573399814666181017120415&partnerID=40&md5=c0022b5846dc14162a4f07a0d52fede6
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Bentham Science Publishers
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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