Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica

Objetivo: Evaluar las características clínicas y angiotomográficas (OCT-A) de los pacientes con membranas epiretinianas (MER) secundarias a oclusiones venosas de la retina (OVR). Métodos: Estudio observacional de corte transversal. Se revisaron retrospectivamente imágenes de OCT-A e historias clínic...

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Fecha de publicación:
2020
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
spa
OAI Identifier:
oai:repository.urosario.edu.co:10336/30790
Acceso en línea:
https://doi.org/10.48713/10336_30790
https://repository.urosario.edu.co/handle/10336/30790
Palabra clave:
Angiotomografía de coherencia óptica
Membranas epiretinianas
Oclusiones venosas de la retina
Enfermedades oftalmológicas
Maculopatía en celofán
Incidencia & prevención de la enfermedad
Optical coherence tomography angiography
Epiretinal membranes
Retinal vein occlusion
Ophthalmological diseases
Cellophane maculopathy
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License
Atribución-NoComercial-SinDerivadas 2.5 Colombia
id EDOCUR2_f20c5973c861ed29c79104b1a473a415
oai_identifier_str oai:repository.urosario.edu.co:10336/30790
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.spa.fl_str_mv Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
dc.title.TranslatedTitle.eng.fl_str_mv Characterization of epiretinal membranes in retinal venous occlusions using optical coherence tomography angiography
title Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
spellingShingle Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
Angiotomografía de coherencia óptica
Membranas epiretinianas
Oclusiones venosas de la retina
Enfermedades oftalmológicas
Maculopatía en celofán
Incidencia & prevención de la enfermedad
Optical coherence tomography angiography
Epiretinal membranes
Retinal vein occlusion
Ophthalmological diseases
Cellophane maculopathy
title_short Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
title_full Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
title_fullStr Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
title_full_unstemmed Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
title_sort Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica
dc.contributor.advisor.none.fl_str_mv Rodríguez Alvira, Francisco José
Rosenstiehl Colón, Shirley Margarita
dc.contributor.none.fl_str_mv Meneses Girado, Said
dc.subject.spa.fl_str_mv Angiotomografía de coherencia óptica
Membranas epiretinianas
Oclusiones venosas de la retina
Enfermedades oftalmológicas
Maculopatía en celofán
topic Angiotomografía de coherencia óptica
Membranas epiretinianas
Oclusiones venosas de la retina
Enfermedades oftalmológicas
Maculopatía en celofán
Incidencia & prevención de la enfermedad
Optical coherence tomography angiography
Epiretinal membranes
Retinal vein occlusion
Ophthalmological diseases
Cellophane maculopathy
dc.subject.ddc.spa.fl_str_mv Incidencia & prevención de la enfermedad
dc.subject.keyword.spa.fl_str_mv Optical coherence tomography angiography
Epiretinal membranes
Retinal vein occlusion
Ophthalmological diseases
Cellophane maculopathy
description Objetivo: Evaluar las características clínicas y angiotomográficas (OCT-A) de los pacientes con membranas epiretinianas (MER) secundarias a oclusiones venosas de la retina (OVR). Métodos: Estudio observacional de corte transversal. Se revisaron retrospectivamente imágenes de OCT-A e historias clínicas de 354 pacientes con diagnóstico de OVR, de los cuales 33 ojos de 33 pacientes cumplieron criterios de inclusión. Se calcularon medidas de tendencia central y medidas de dispersión de las variables cuantitativas según su distribución (kolmogorov-smirnov). Las variables cualitativas fueron descritas en frecuencias y porcentajes. Resultados: Fueron incluidos en el análisis treinta y tres ojos. El promedio de edad fue 68,7 años (DE: 12,4) con un 54.5% de mujeres (n:18). La mediana de agudeza visual (AV) LogMAR 0,70 (RIQ: 1,00). El 57,6% (n:19) presentaron oclusión de vena central, 33,3% (n:11) oclusión de rama venosa y el 9,1% (n:3) oclusión hemicentral. El tiempo entre el diagnóstico de OVR y el de MER fue en promedio de 14,4 meses (RIQ: 26) y previo al diagnóstico de MER habían recibido 3,8 (DE:3,7) inyecciones de antiangiogénico. El grosor retiniano central (GRC) promedio fue de 327 um (DE: 132,3) con disrupción en la integridad de la membrana limitante externa (MLE) y zona elipsoide (ZE) en 60,6% (n:20) y 66.7% (n:22) respectivamente. Hubo presencia de espacios cistoides intraretinianos en la mayoría de pacientes (60,6% n:20) y desorganización de capas retinianas internas (DRIL) en 42,2% (n:14). Se encontraron capas foveales internas ectópicas solo en 12.1% (n:4) de los ojos. La localización de las MER fue en su mayoría extrafoveal (75,7% n: 25) con un patrón de adherencia a la superficie de la retina mixto (global y focal) en un 45,5% (n: 15) de los casos. La zona avascular foveal (ZAF) total fue de 280 um (RIQ: 221um). Se observó que los ojos con MER foveal y disrupción en la MLE y ZE mostraron una tendencia a tener peor AV. Conclusiones: Las características estructurales y vasculares en la retina de pacientes con MER secundarias a OVR corresponden a cambios propios de la patología vascular. Este grupo de pacientes no comparten las características angiotomográficas descritas para MER idiopáticas. La disrupción de la MLE y ZE puede estar asociado con peor agudeza visual.
publishDate 2020
dc.date.created.none.fl_str_mv 2020-12-14
dc.date.accessioned.none.fl_str_mv 2021-01-25T14:16:03Z
dc.date.available.none.fl_str_mv 2021-01-25T14:16:03Z
dc.type.eng.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.spa.fl_str_mv Descriptivo observacional retrospectivo
dc.type.spa.spa.fl_str_mv Trabajo de grado
dc.identifier.doi.none.fl_str_mv https://doi.org/10.48713/10336_30790
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/30790
url https://doi.org/10.48713/10336_30790
https://repository.urosario.edu.co/handle/10336/30790
dc.language.iso.spa.fl_str_mv spa
language spa
dc.rights.spa.fl_str_mv Atribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
dc.rights.economicrights.spa.fl_str_mv Fundación Oftalmológica Nacional
dc.rights.uri.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/co/
rights_invalid_str_mv Atribución-NoComercial-SinDerivadas 2.5 Colombia
Abierto (Texto Completo)
Fundación Oftalmológica Nacional
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad del Rosario
dc.publisher.department.spa.fl_str_mv Escuela de Medicina y Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Especialización en Retina y Vítreo
institution Universidad del Rosario
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spelling Meneses Girado, SaidRodríguez Alvira, Francisco José812405a7-5bbd-405e-912f-ff1fce2ce9c1600Rosenstiehl Colón, Shirley Margarita6d8d9e9f-0b06-47ac-85ef-126b45e9cc82600Daza Irreño, Laura AndreaEspecialista en Retina y VítreoFull time4c8e8b37-3987-42eb-a229-4101b176eafc6002021-01-25T14:16:03Z2021-01-25T14:16:03Z2020-12-14Objetivo: Evaluar las características clínicas y angiotomográficas (OCT-A) de los pacientes con membranas epiretinianas (MER) secundarias a oclusiones venosas de la retina (OVR). Métodos: Estudio observacional de corte transversal. Se revisaron retrospectivamente imágenes de OCT-A e historias clínicas de 354 pacientes con diagnóstico de OVR, de los cuales 33 ojos de 33 pacientes cumplieron criterios de inclusión. Se calcularon medidas de tendencia central y medidas de dispersión de las variables cuantitativas según su distribución (kolmogorov-smirnov). Las variables cualitativas fueron descritas en frecuencias y porcentajes. Resultados: Fueron incluidos en el análisis treinta y tres ojos. El promedio de edad fue 68,7 años (DE: 12,4) con un 54.5% de mujeres (n:18). La mediana de agudeza visual (AV) LogMAR 0,70 (RIQ: 1,00). El 57,6% (n:19) presentaron oclusión de vena central, 33,3% (n:11) oclusión de rama venosa y el 9,1% (n:3) oclusión hemicentral. El tiempo entre el diagnóstico de OVR y el de MER fue en promedio de 14,4 meses (RIQ: 26) y previo al diagnóstico de MER habían recibido 3,8 (DE:3,7) inyecciones de antiangiogénico. El grosor retiniano central (GRC) promedio fue de 327 um (DE: 132,3) con disrupción en la integridad de la membrana limitante externa (MLE) y zona elipsoide (ZE) en 60,6% (n:20) y 66.7% (n:22) respectivamente. Hubo presencia de espacios cistoides intraretinianos en la mayoría de pacientes (60,6% n:20) y desorganización de capas retinianas internas (DRIL) en 42,2% (n:14). Se encontraron capas foveales internas ectópicas solo en 12.1% (n:4) de los ojos. La localización de las MER fue en su mayoría extrafoveal (75,7% n: 25) con un patrón de adherencia a la superficie de la retina mixto (global y focal) en un 45,5% (n: 15) de los casos. La zona avascular foveal (ZAF) total fue de 280 um (RIQ: 221um). Se observó que los ojos con MER foveal y disrupción en la MLE y ZE mostraron una tendencia a tener peor AV. Conclusiones: Las características estructurales y vasculares en la retina de pacientes con MER secundarias a OVR corresponden a cambios propios de la patología vascular. Este grupo de pacientes no comparten las características angiotomográficas descritas para MER idiopáticas. La disrupción de la MLE y ZE puede estar asociado con peor agudeza visual.Purpose: To evaluate clinical and angiotomography (OCT-A) characteristics of patients with epiretinal membranes (ERM) secondary to retinal vein occlusions (RVO). Method: Cross sectional study. OCT-A images and medical records of 354 patients diagnosed with RVO were retrospectively reviewed, of which 33 eyes from 33 patients met inclusion criteria. Measures of central tendency and measures of dispersion of quantitative variables according to their distribution (kolmogorov-smirnov) were calculated. The qualitative variables were described in frequencies and percentages. Results: The mean age was 68.7 years (SD: 12.4) with 54.5% women (n: 18). Median visual acuity (AV) LogMAR 0.70 (IQR: 1.00). 57.6% (n: 19) had a diagnosis of central retinal vein occlusion (CRVO) 33.3% (n: 11) branch retinal vein occlusion (BRVO) and 9.1% (n: 3) hemicentral vein occlusion (HVO). The time between the diagnosis of RVO and ERM averaged 14.4 months (IQR: 26), and previous to the diagnosis of ERM received 3.8 (SD: 3.7) antiangiogenic injections. The mean central retinal thickness (CRT) was 327 um (SD: 132.3) with disruption of the integrity of the external limiting membrane (ELM) and ellipsoid zone (EZ) in 60.6% (n: 20) and 66.7% % (n: 22) respectively. There was presence of intraretinal cystoid spaces in most patients (60.6% n: 20) and disorganization of the inner retinal layer (DRIL) in 42.2% (n: 14). Ectopic inner foveal layers (EIFL) were found only in 12.1% (n: 4) of the eyes. The ERM location was mostly extrafoveal (75.7% n: 25) with a mixed pattern of adherence to the retinal surface (global and focal) in 45.5% (n: 15) of the cases. The mean foveal avascular zone (FAZ) was 280 um (IQR: 221um). Eyes with foveal-involving MER and disruption in MLE and ZE show a tendency to have worse VA. Conclusions: The structural and vascular retinal characteristics of patients with ERM secondary to RVO correspond to inherent changes to vascular pathology. This group of patients does not share the angiotomography characteristics described for idiopathic ERM. Disruption of the MLE and ZE may be associated with worse visual outcome.2023-01-25 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2023-01-242021-01-25 09:20:02: Script de automatizacion de embargos. Correo recibido: Laura Andrea Daza Irreño Dom 10/01/2021 12:37 PM Señores REPOSITORIO INSTITUCIONAL Cordial saludo, Por medio del presente correo quisiera solicitar que el trabajo de grado aprobado por la vicedecanatura de investigación para optar por el título de especialista en retina y vítreo llamado "Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía e coherencia óptica", sea bloqueado del repositorio institucional por los siguientes 2 años ya que en el momento nos encontramos realizando los ajustes para someterlo a publicación en una revista internacional pendiente por definir. Agradezco la atención prestada. Atentamente, Laura Andrea Daza Irreño c.c. 1095920058 de Girón (S/der) - Respuesta: Repositorio Institucional EdocUR Lun 25/01/2021 9:18 AM Respetada Laura Daza, reciba un cordial saludo, Hemos realizado la publicación de su documento: Caracterización de membranas epiretinianas en oclusiones venosas de la retina mediante angiotomografía de coherencia óptica, el cual puede consultar en el siguiente enlace: https://repository.urosario.edu.co/handle/10336/30790 De acuerdo con su solicitud, el documento ha quedado embargado por 2 años hasta el 2023-01-25 en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica. Quedamos atentos a cualquier inquietud o sugerencia.application/pdfhttps://doi.org/10.48713/10336_30790 https://repository.urosario.edu.co/handle/10336/30790spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludEspecialización en Retina y VítreoAtribución-NoComercial-SinDerivadas 2.5 ColombiaAbierto (Texto Completo)Fundación Oftalmológica NacionalEL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.http://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2Iwanoff A. 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