Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world

Introduction: Although the routine use of manual thrombus aspiration (MTA) in patients with ST-elevation myocardial infarction (STEMI) provides no benefit compared to conventional primary percutaneous coronary intervention (PCI), the use of this technique in the real world could be associated with t...

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Tipo de recurso:
Fecha de publicación:
2020
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/25103
Acceso en línea:
https://doi.org/10.1016/j.ijcha.2019.100436
https://repository.urosario.edu.co/handle/10336/25103
Palabra clave:
Adult
Article
Clinical practice
Cohort analysis
Controlled study
Coronary angiography
Coronary artery thrombosis
Disease association
Disease burden
Female
Human
Major clinical study
Male
Middle aged
Outcome assessment
Percutaneous coronary intervention
Priority journal
Retrospective study
Right coronary artery
St segment elevation myocardial infarction
Thrombus aspiration
Coronary angiography
Coronary artery disease
Coronary thrombosis
Percutaneous coronary intervention
St elevation myocardial infarction
Thrombosis
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License
Abierto (Texto Completo)
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spelling 4a397a2e-ef21-4a3c-b105-77ea550019ac-189e8bb91-9671-4fd7-873c-0426fc673e68-104fb208e-0eb3-40c6-b6ea-5ffa4fa8efa1-12020-06-11T13:22:21Z2020-06-11T13:22:21Z2020Introduction: Although the routine use of manual thrombus aspiration (MTA) in patients with ST-elevation myocardial infarction (STEMI) provides no benefit compared to conventional primary percutaneous coronary intervention (PCI), the use of this technique in the real world could be associated with the intracoronary thrombotic burden. The objective of this study is to evaluate whether the use of MTA is directly related to a high intracoronary thrombotic burden as defined by the Thrombolysis in Myocardial Infarction (TIMI) scale, in patients with STEMI.Methods: Descriptive retrospective study of patients with a diagnosis of STEMI, in whom the use of MTA was assessed according to the coronary thrombus grading.Results: A total of 173 patients were included, with a mean age of 62 years, of whom 78% were male. Manual thrombus aspiration was performed in 52 (30%) of these patients, 98% (51/52) had a high thrombus burden (TIMI thrombus burden grade > 4), compared to 39.6% (48/121) of the patients who did not undergo MTA. Thus, a high thrombus burden was significantly related to the use of MTA (p<0.0001). There were no ischemic stroke or deaths due to cardiovascular causes in the MTA group during hospitalization.Conclusion: A high thrombus burden, as classified by the TIMI scale, was significantly associated with the use of MTA. This technique was not related with any major cardiovascular events. (C) 2019 The Authors. Published by Elsevier B.V.application/pdfhttps://doi.org/10.1016/j.ijcha.2019.1004362352-9067https://repository.urosario.edu.co/handle/10336/25103engElsevier Ireland LtdIJC Heart and VasculatureVol. 26IJC Heart and Vasculature, ISSN: 2352-9067, Vol.26, No. (2020); pp. -https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075751947&doi=10.1016%2fj.ijcha.2019.100436&partnerID=40&md5=1ad0e5674472bbb4e11da2f426d4ec4aAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAdultArticleClinical practiceCohort analysisControlled studyCoronary angiographyCoronary artery thrombosisDisease associationDisease burdenFemaleHumanMajor clinical studyMaleMiddle agedOutcome assessmentPercutaneous coronary interventionPriority journalRetrospective studyRight coronary arterySt segment elevation myocardial infarctionThrombus aspirationCoronary angiographyCoronary artery diseaseCoronary thrombosisPercutaneous coronary interventionSt elevation myocardial infarctionThrombosisAssociation of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real worldarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501del Portillo, Juan HernandoEcheverri, DaríoCabrales, JaimeORIGINAL1-s2-0-S2352906719302003-main.pdfapplication/pdf747820https://repository.urosario.edu.co/bitstreams/b2569009-e664-45d1-b337-409956381834/download2aae1f82a9079cbda12e8be97e9ffb5aMD51TEXT1-s2-0-S2352906719302003-main.pdf.txt1-s2-0-S2352906719302003-main.pdf.txtExtracted texttext/plain28678https://repository.urosario.edu.co/bitstreams/2536d9bf-ac64-49a4-9872-4e4596bbaba7/download7afe9e7a547a016c91ac765371ddf9b8MD52THUMBNAIL1-s2-0-S2352906719302003-main.pdf.jpg1-s2-0-S2352906719302003-main.pdf.jpgGenerated Thumbnailimage/jpeg4611https://repository.urosario.edu.co/bitstreams/5f5a49b4-8c7f-4953-97b2-4a899377641a/download5190948db18db0b5e194cbe893abfef7MD5310336/25103oai:repository.urosario.edu.co:10336/251032021-06-03 00:50:54.143https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
title Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
spellingShingle Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
Adult
Article
Clinical practice
Cohort analysis
Controlled study
Coronary angiography
Coronary artery thrombosis
Disease association
Disease burden
Female
Human
Major clinical study
Male
Middle aged
Outcome assessment
Percutaneous coronary intervention
Priority journal
Retrospective study
Right coronary artery
St segment elevation myocardial infarction
Thrombus aspiration
Coronary angiography
Coronary artery disease
Coronary thrombosis
Percutaneous coronary intervention
St elevation myocardial infarction
Thrombosis
title_short Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
title_full Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
title_fullStr Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
title_full_unstemmed Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
title_sort Association of the use of manual thrombus aspiration with intracoronary thrombotic burden in patients with ST segment elevation myocardial infarction in the real world
dc.subject.keyword.spa.fl_str_mv Adult
Article
Clinical practice
Cohort analysis
Controlled study
Coronary angiography
Coronary artery thrombosis
Disease association
Disease burden
Female
Human
Major clinical study
Male
Middle aged
Outcome assessment
Percutaneous coronary intervention
Priority journal
Retrospective study
Right coronary artery
St segment elevation myocardial infarction
Thrombus aspiration
Coronary angiography
Coronary artery disease
Coronary thrombosis
Percutaneous coronary intervention
St elevation myocardial infarction
Thrombosis
topic Adult
Article
Clinical practice
Cohort analysis
Controlled study
Coronary angiography
Coronary artery thrombosis
Disease association
Disease burden
Female
Human
Major clinical study
Male
Middle aged
Outcome assessment
Percutaneous coronary intervention
Priority journal
Retrospective study
Right coronary artery
St segment elevation myocardial infarction
Thrombus aspiration
Coronary angiography
Coronary artery disease
Coronary thrombosis
Percutaneous coronary intervention
St elevation myocardial infarction
Thrombosis
description Introduction: Although the routine use of manual thrombus aspiration (MTA) in patients with ST-elevation myocardial infarction (STEMI) provides no benefit compared to conventional primary percutaneous coronary intervention (PCI), the use of this technique in the real world could be associated with the intracoronary thrombotic burden. The objective of this study is to evaluate whether the use of MTA is directly related to a high intracoronary thrombotic burden as defined by the Thrombolysis in Myocardial Infarction (TIMI) scale, in patients with STEMI.Methods: Descriptive retrospective study of patients with a diagnosis of STEMI, in whom the use of MTA was assessed according to the coronary thrombus grading.Results: A total of 173 patients were included, with a mean age of 62 years, of whom 78% were male. Manual thrombus aspiration was performed in 52 (30%) of these patients, 98% (51/52) had a high thrombus burden (TIMI thrombus burden grade > 4), compared to 39.6% (48/121) of the patients who did not undergo MTA. Thus, a high thrombus burden was significantly related to the use of MTA (p<0.0001). There were no ischemic stroke or deaths due to cardiovascular causes in the MTA group during hospitalization.Conclusion: A high thrombus burden, as classified by the TIMI scale, was significantly associated with the use of MTA. This technique was not related with any major cardiovascular events. (C) 2019 The Authors. Published by Elsevier B.V.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-06-11T13:22:21Z
dc.date.available.none.fl_str_mv 2020-06-11T13:22:21Z
dc.date.created.spa.fl_str_mv 2020
dc.type.eng.fl_str_mv article
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dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.ijcha.2019.100436
dc.identifier.issn.none.fl_str_mv 2352-9067
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/25103
url https://doi.org/10.1016/j.ijcha.2019.100436
https://repository.urosario.edu.co/handle/10336/25103
identifier_str_mv 2352-9067
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.citationTitle.none.fl_str_mv IJC Heart and Vasculature
dc.relation.citationVolume.none.fl_str_mv Vol. 26
dc.relation.ispartof.spa.fl_str_mv IJC Heart and Vasculature, ISSN: 2352-9067, Vol.26, No. (2020); pp. -
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075751947&doi=10.1016%2fj.ijcha.2019.100436&partnerID=40&md5=1ad0e5674472bbb4e11da2f426d4ec4a
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