FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients
El papel de forkhead-box A1 (FOXA1) y el receptor de andrógenos (AR) en el cáncer de mama (BC) ha sido ampliamente estudiado. Sin embargo, el papel pronóstico de su coexpresión en el receptor de estrógeno positivo (ER +) BC no se ha investigado hasta ahora. El objetivo del presente estudio fue evalu...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/25709
- Acceso en línea:
- https://doi.org/10.1186/s12885-018-4624-y
https://repository.urosario.edu.co/handle/10336/25709
- Palabra clave:
- Adulto
Anciano
Neoplasias de la mama
Hembra
Factor nuclear de hepatocitos 3-alfa
Humanos
Inmunohistoquímica
Edad media
Pronóstico
Receptores
andrógenos
Receptores
estrógenos
Adult
Aged
Breast Neoplasms
Female
Hepatocyte Nuclear Factor 3-alpha
Humans
Immunohistochemistry
Middle Aged
Prognosis
Receptors
Androgen
Receptors
Estrogen
- Rights
- License
- Abierto (Texto Completo)
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e14757fa-5d19-4f7b-bb3d-f71a50e6feca-1ba17c286-5534-4272-8919-feceeeae37f2-18f472f55-3b11-4de1-af1f-b2ff5c239c8e-1a0931f96-cbc1-4b6a-957c-fbdbc1198cf3-1d036eea3-7f63-49f6-9bcd-10f9a9691f48-1947b1694-7d28-49e4-adb9-47e5969659a9-1c134377b-ccb9-4029-850f-9d37d0891531-160685d7c-4983-4801-b94d-d7f7b7d6711e-16fe4cfe9-660b-4e20-a792-c92836f6188c-171301819-efb6-4452-9a85-3dbceb529bfa-11413cc05-fcd1-4b0a-a257-2b7096e687ba-1f8318d70-1883-41a3-93be-68c8c96aa458-1daef2be9-7f33-484d-bc52-d9b9dee767c4-12d7e8bea-4138-447d-b84c-0182522e3861-193cdcd0f-f4c6-44e2-b0a5-9930b6f34677-12020-07-30T21:01:58Z2020-07-30T21:01:58Z2018-12El papel de forkhead-box A1 (FOXA1) y el receptor de andrógenos (AR) en el cáncer de mama (BC) ha sido ampliamente estudiado. Sin embargo, el papel pronóstico de su coexpresión en el receptor de estrógeno positivo (ER +) BC no se ha investigado hasta ahora. El objetivo del presente estudio fue evaluar la coexpresión (proteína y ARNm) de FOXA1 y AR en pacientes con BC, con el fin de evaluar su impacto pronóstico según el estado de la sala de emergencias.The role of forkhead-box A1 (FOXA1) and Androgen receptor (AR) in breast cancer (BC) has been extensively studied. However, the prognostic role of their co-expression in Estrogen receptor positive (ER+) BC has not been investigated so far. The aim of the present study was thus to assess the co-expression (protein and mRNA) of FOXA1 and AR in BC patients, in order to evaluate their prognostic impact according to ER status.application/pdfhttps://doi.org/10.1186/s12885-018-4624-yISSN: 1471-2407https://repository.urosario.edu.co/handle/10336/25709engSpringer NatureNo. 1703BMC CancerVol. 18BMC Cancer, ISSN: 14712407, Vol.18, No.1 (2018-12); pp. 703https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4624-yAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAdultoAncianoNeoplasias de la mamaHembraFactor nuclear de hepatocitos 3-alfaHumanosInmunohistoquímicaEdad mediaPronósticoReceptoresandrógenosReceptoresestrógenosAdultAgedBreast NeoplasmsFemaleHepatocyte Nuclear Factor 3-alphaHumansImmunohistochemistryMiddle AgedPrognosisReceptorsAndrogenReceptorsEstrogenFOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patientsarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Rangel, NelsonFortunati, NicolettaOsella-Abate, SimonaAnnaratone, LauraIsella, ClaudioCatalano, Maria GraziellaRinella, LetiziaMetovic, JasnaBoldorini, RenzoBalmativola, DavideFerrando, PietroMarano, FrancescaCassoni, PaolaSapino, AnnaCastellano, IsabellaORIGINALs12885-018-4624-y.pdfapplication/pdf1185461https://repository.urosario.edu.co/bitstreams/215d4aa1-5b2d-40f7-9adc-483a5af6d400/downloadc87f2b59bb1fd5cb9647ad05368a7e05MD51TEXTs12885-018-4624-y.pdf.txts12885-018-4624-y.pdf.txtExtracted texttext/plain35830https://repository.urosario.edu.co/bitstreams/a61556a2-53b2-44a7-989d-ce070534eccd/download3e3a6359800860ee67cc1e93dc248ec4MD52THUMBNAILs12885-018-4624-y.pdf.jpgs12885-018-4624-y.pdf.jpgGenerated Thumbnailimage/jpeg4794https://repository.urosario.edu.co/bitstreams/6799ea36-b639-4cf8-95dc-6508be3d8350/download8723e9f64c406a8e143406df6269f1fdMD5310336/25709oai:repository.urosario.edu.co:10336/257092021-06-03 00:51:02.892https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
| dc.title.spa.fl_str_mv |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| title |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| spellingShingle |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients Adulto Anciano Neoplasias de la mama Hembra Factor nuclear de hepatocitos 3-alfa Humanos Inmunohistoquímica Edad media Pronóstico Receptores andrógenos Receptores estrógenos Adult Aged Breast Neoplasms Female Hepatocyte Nuclear Factor 3-alpha Humans Immunohistochemistry Middle Aged Prognosis Receptors Androgen Receptors Estrogen |
| title_short |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| title_full |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| title_fullStr |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| title_full_unstemmed |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| title_sort |
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients |
| dc.subject.spa.fl_str_mv |
Adulto Anciano Neoplasias de la mama Hembra Factor nuclear de hepatocitos 3-alfa Humanos Inmunohistoquímica Edad media Pronóstico Receptores andrógenos Receptores estrógenos |
| topic |
Adulto Anciano Neoplasias de la mama Hembra Factor nuclear de hepatocitos 3-alfa Humanos Inmunohistoquímica Edad media Pronóstico Receptores andrógenos Receptores estrógenos Adult Aged Breast Neoplasms Female Hepatocyte Nuclear Factor 3-alpha Humans Immunohistochemistry Middle Aged Prognosis Receptors Androgen Receptors Estrogen |
| dc.subject.keyword.spa.fl_str_mv |
Adult Aged Breast Neoplasms Female Hepatocyte Nuclear Factor 3-alpha Humans Immunohistochemistry Middle Aged Prognosis Receptors Androgen Receptors Estrogen |
| description |
El papel de forkhead-box A1 (FOXA1) y el receptor de andrógenos (AR) en el cáncer de mama (BC) ha sido ampliamente estudiado. Sin embargo, el papel pronóstico de su coexpresión en el receptor de estrógeno positivo (ER +) BC no se ha investigado hasta ahora. El objetivo del presente estudio fue evaluar la coexpresión (proteína y ARNm) de FOXA1 y AR en pacientes con BC, con el fin de evaluar su impacto pronóstico según el estado de la sala de emergencias. |
| publishDate |
2018 |
| dc.date.created.spa.fl_str_mv |
2018-12 |
| dc.date.accessioned.none.fl_str_mv |
2020-07-30T21:01:58Z |
| dc.date.available.none.fl_str_mv |
2020-07-30T21:01:58Z |
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article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_6501 |
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Artículo |
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https://doi.org/10.1186/s12885-018-4624-y |
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ISSN: 1471-2407 |
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https://repository.urosario.edu.co/handle/10336/25709 |
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https://doi.org/10.1186/s12885-018-4624-y https://repository.urosario.edu.co/handle/10336/25709 |
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ISSN: 1471-2407 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
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No. 1 |
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703 |
| dc.relation.citationTitle.none.fl_str_mv |
BMC Cancer |
| dc.relation.citationVolume.none.fl_str_mv |
Vol. 18 |
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BMC Cancer, ISSN: 14712407, Vol.18, No.1 (2018-12); pp. 703 |
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https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-018-4624-y |
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Abierto (Texto Completo) |
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application/pdf |
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Springer Nature |
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