Myeloid-derived-supressor cells as regulators of th eimmune system
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in h...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2009
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/26624
- Acceso en línea:
- https://doi.org/10.1038/nri2506
https://repository.urosario.edu.co/handle/10336/26624
- Palabra clave:
- Immunosuppressi
Suppression
- Rights
- License
- Restringido (Acceso a grupos específicos)
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e93dc376-908a-4a78-b07d-9632a50987ed-18fd98f5c-0348-45db-a8dd-d3522a2937d7-12020-08-19T14:39:55Z2020-08-19T14:39:55Z2009-03Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in healthy individuals and in the context of various diseases. In this Review, we discuss the origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit.application/pdfhttps://doi.org/10.1038/nri2506ISSN: 1474-1733EISSN: 1474-1741https://repository.urosario.edu.co/handle/10336/26624engNature reviews Immunology174162Nature Reviews ImmunologyVol. 9Nature Reviews Immunology, ISSN: 1474-1733 ; EISSN: 1474-1741, Vol.9 (2009);pp. 162–174https://www.nature.com/articles/nri2506#Abs3Restringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecNature Reviews Immunologyinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURImmunosuppressiSuppressionMyeloid-derived-supressor cells as regulators of th eimmune systemCélulas supresoras derivadas de mieloides como reguladoras del sistema inmunológicoarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Gabilovich, DmitryNagaraj, Srinivas10336/26624oai:repository.urosario.edu.co:10336/266242021-06-03 00:49:56.034https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
Myeloid-derived-supressor cells as regulators of th eimmune system |
dc.title.TranslatedTitle.spa.fl_str_mv |
Células supresoras derivadas de mieloides como reguladoras del sistema inmunológico |
title |
Myeloid-derived-supressor cells as regulators of th eimmune system |
spellingShingle |
Myeloid-derived-supressor cells as regulators of th eimmune system Immunosuppressi Suppression |
title_short |
Myeloid-derived-supressor cells as regulators of th eimmune system |
title_full |
Myeloid-derived-supressor cells as regulators of th eimmune system |
title_fullStr |
Myeloid-derived-supressor cells as regulators of th eimmune system |
title_full_unstemmed |
Myeloid-derived-supressor cells as regulators of th eimmune system |
title_sort |
Myeloid-derived-supressor cells as regulators of th eimmune system |
dc.subject.keyword.spa.fl_str_mv |
Immunosuppressi Suppression |
topic |
Immunosuppressi Suppression |
description |
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in healthy individuals and in the context of various diseases. In this Review, we discuss the origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit. |
publishDate |
2009 |
dc.date.created.spa.fl_str_mv |
2009-03 |
dc.date.accessioned.none.fl_str_mv |
2020-08-19T14:39:55Z |
dc.date.available.none.fl_str_mv |
2020-08-19T14:39:55Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1038/nri2506 |
dc.identifier.issn.none.fl_str_mv |
ISSN: 1474-1733 EISSN: 1474-1741 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/26624 |
url |
https://doi.org/10.1038/nri2506 https://repository.urosario.edu.co/handle/10336/26624 |
identifier_str_mv |
ISSN: 1474-1733 EISSN: 1474-1741 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
174 |
dc.relation.citationStartPage.none.fl_str_mv |
162 |
dc.relation.citationTitle.none.fl_str_mv |
Nature Reviews Immunology |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 9 |
dc.relation.ispartof.spa.fl_str_mv |
Nature Reviews Immunology, ISSN: 1474-1733 ; EISSN: 1474-1741, Vol.9 (2009);pp. 162–174 |
dc.relation.uri.spa.fl_str_mv |
https://www.nature.com/articles/nri2506#Abs3 |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_16ec |
dc.rights.acceso.spa.fl_str_mv |
Restringido (Acceso a grupos específicos) |
rights_invalid_str_mv |
Restringido (Acceso a grupos específicos) http://purl.org/coar/access_right/c_16ec |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Nature reviews Immunology |
dc.source.spa.fl_str_mv |
Nature Reviews Immunology |
institution |
Universidad del Rosario |
dc.source.instname.none.fl_str_mv |
instname:Universidad del Rosario |
dc.source.reponame.none.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
repository.name.fl_str_mv |
Repositorio institucional EdocUR |
repository.mail.fl_str_mv |
edocur@urosario.edu.co |
_version_ |
1814167511194664960 |