Myeloid-derived-supressor cells as regulators of th eimmune system

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in h...

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Autores:
Tipo de recurso:
Fecha de publicación:
2009
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/26624
Acceso en línea:
https://doi.org/10.1038/nri2506
https://repository.urosario.edu.co/handle/10336/26624
Palabra clave:
Immunosuppressi
Suppression
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License
Restringido (Acceso a grupos específicos)
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oai_identifier_str oai:repository.urosario.edu.co:10336/26624
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling e93dc376-908a-4a78-b07d-9632a50987ed-18fd98f5c-0348-45db-a8dd-d3522a2937d7-12020-08-19T14:39:55Z2020-08-19T14:39:55Z2009-03Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in healthy individuals and in the context of various diseases. In this Review, we discuss the origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit.application/pdfhttps://doi.org/10.1038/nri2506ISSN: 1474-1733EISSN: 1474-1741https://repository.urosario.edu.co/handle/10336/26624engNature reviews Immunology174162Nature Reviews ImmunologyVol. 9Nature Reviews Immunology, ISSN: 1474-1733 ; EISSN: 1474-1741, Vol.9 (2009);pp. 162–174https://www.nature.com/articles/nri2506#Abs3Restringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecNature Reviews Immunologyinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURImmunosuppressiSuppressionMyeloid-derived-supressor cells as regulators of th eimmune systemCélulas supresoras derivadas de mieloides como reguladoras del sistema inmunológicoarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Gabilovich, DmitryNagaraj, Srinivas10336/26624oai:repository.urosario.edu.co:10336/266242021-06-03 00:49:56.034https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Myeloid-derived-supressor cells as regulators of th eimmune system
dc.title.TranslatedTitle.spa.fl_str_mv Células supresoras derivadas de mieloides como reguladoras del sistema inmunológico
title Myeloid-derived-supressor cells as regulators of th eimmune system
spellingShingle Myeloid-derived-supressor cells as regulators of th eimmune system
Immunosuppressi
Suppression
title_short Myeloid-derived-supressor cells as regulators of th eimmune system
title_full Myeloid-derived-supressor cells as regulators of th eimmune system
title_fullStr Myeloid-derived-supressor cells as regulators of th eimmune system
title_full_unstemmed Myeloid-derived-supressor cells as regulators of th eimmune system
title_sort Myeloid-derived-supressor cells as regulators of th eimmune system
dc.subject.keyword.spa.fl_str_mv Immunosuppressi
Suppression
topic Immunosuppressi
Suppression
description Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expand during cancer, inflammation and infection, and that have a remarkable ability to suppress T-cell responses. These cells constitute a unique component of the immune system that regulates immune responses in healthy individuals and in the context of various diseases. In this Review, we discuss the origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit.
publishDate 2009
dc.date.created.spa.fl_str_mv 2009-03
dc.date.accessioned.none.fl_str_mv 2020-08-19T14:39:55Z
dc.date.available.none.fl_str_mv 2020-08-19T14:39:55Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1038/nri2506
dc.identifier.issn.none.fl_str_mv ISSN: 1474-1733
EISSN: 1474-1741
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/26624
url https://doi.org/10.1038/nri2506
https://repository.urosario.edu.co/handle/10336/26624
identifier_str_mv ISSN: 1474-1733
EISSN: 1474-1741
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 174
dc.relation.citationStartPage.none.fl_str_mv 162
dc.relation.citationTitle.none.fl_str_mv Nature Reviews Immunology
dc.relation.citationVolume.none.fl_str_mv Vol. 9
dc.relation.ispartof.spa.fl_str_mv Nature Reviews Immunology, ISSN: 1474-1733 ; EISSN: 1474-1741, Vol.9 (2009);pp. 162–174
dc.relation.uri.spa.fl_str_mv https://www.nature.com/articles/nri2506#Abs3
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.acceso.spa.fl_str_mv Restringido (Acceso a grupos específicos)
rights_invalid_str_mv Restringido (Acceso a grupos específicos)
http://purl.org/coar/access_right/c_16ec
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Nature reviews Immunology
dc.source.spa.fl_str_mv Nature Reviews Immunology
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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