Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central
El cáncer gástrico representa un problema de salud pública debido a su alta incidencia. La supervivencia de todos los tipos de cáncer en forma global se calcula en 68.9% a 5 años, en contraste con el cáncer gástrico donde la supervivencia alcanza el 32%. A nivell local algunos estudios han encontrad...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2016
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- spa
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/13223
- Acceso en línea:
- https://doi.org/10.48713/10336_13223
http://repository.urosario.edu.co//handle/10336/13223
- Palabra clave:
- Neoplasia
Sobrevida
estómago
Pronóstico
Tumor Carcinoide
Enfermedades
Neoplasms
Survey
Stomach
Prognosis
Neoplasmas::Estudio de Casos
Adenocarcinoma::Estudio de Casos
Síndrome carcinoide maligno::Estudio de Casos
- Rights
- License
- Abierto (Texto Completo)
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oai_identifier_str |
oai:repository.urosario.edu.co:10336/13223 |
network_acronym_str |
EDOCUR2 |
network_name_str |
Repositorio EdocUR - U. Rosario |
repository_id_str |
|
dc.title.spa.fl_str_mv |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
title |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
spellingShingle |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central Neoplasia Sobrevida estómago Pronóstico Tumor Carcinoide Enfermedades Neoplasms Survey Stomach Prognosis Neoplasmas::Estudio de Casos Adenocarcinoma::Estudio de Casos Síndrome carcinoide maligno::Estudio de Casos |
title_short |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
title_full |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
title_fullStr |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
title_full_unstemmed |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
title_sort |
Supervivencia en pacientes adultos con diagnóstico de adenocarcinoma gástrico atendidos en el Hospital Militar Central |
dc.contributor.advisor.none.fl_str_mv |
Juliao-Nacith, Haroldo Hernando Isaza Restrepo, Andrés |
dc.subject.spa.fl_str_mv |
Neoplasia Sobrevida estómago Pronóstico Tumor Carcinoide |
topic |
Neoplasia Sobrevida estómago Pronóstico Tumor Carcinoide Enfermedades Neoplasms Survey Stomach Prognosis Neoplasmas::Estudio de Casos Adenocarcinoma::Estudio de Casos Síndrome carcinoide maligno::Estudio de Casos |
dc.subject.ddc.none.fl_str_mv |
Enfermedades |
dc.subject.keyword.eng.fl_str_mv |
Neoplasms Survey Stomach Prognosis |
dc.subject.lemb.spa.fl_str_mv |
Neoplasmas::Estudio de Casos Adenocarcinoma::Estudio de Casos Síndrome carcinoide maligno::Estudio de Casos |
description |
El cáncer gástrico representa un problema de salud pública debido a su alta incidencia. La supervivencia de todos los tipos de cáncer en forma global se calcula en 68.9% a 5 años, en contraste con el cáncer gástrico donde la supervivencia alcanza el 32%. A nivell local algunos estudios han encontrado sobrevida a 5 años del 10,6% en contraposición con países donde se encuentran tasas de sobrevida del 48,5%. La toma de dato se realizó de los registros del servicio de patología y en las historias clínicas del Hospital Militar Central del personal diagnosticado con adenocarcinoma gástrico en el periodo entre 2012 y 2015. Se obtuvieron 98 registros, la media de edad fue 59,3 años (59,3±18,12). Por sexo la distribución fue hombres 74.5% y mujeres 25.5%; por tipo histológico intestinal 52%, difuso 39.8% y mixto 8.2%; Por estadios, el IV fue el más frecuente con 45.9%. La tasa de supervivencia global fue de 19%. La mediana de supervivencia global fue de 18.2 meses (IC del 95% de 11.5-24.8) y la tasa de supervivencia para menores de 60 años se estimó en 25% y para mayores de 60 años fue 24%, analizadas a 4 años. La tasa global de sobrevida fue de 19%, inferior a la reportada en países desarrollados, aunque la sobrevida para el primer y segundo año son similares a éstos, lo que se explica por un tratamiento adecuado pero un diagnóstico tardío, ya que el 77.5% de los pacientes de nuestro estudio estaban en estadios III y IV. |
publishDate |
2016 |
dc.date.created.none.fl_str_mv |
2016-11-28 |
dc.date.issued.none.fl_str_mv |
2016 |
dc.date.accessioned.none.fl_str_mv |
2017-04-03T19:19:56Z |
dc.date.available.none.fl_str_mv |
2017-04-03T19:19:56Z |
dc.type.eng.fl_str_mv |
bachelorThesis |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_7a1f |
dc.type.spa.spa.fl_str_mv |
Trabajo de grado |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.48713/10336_13223 |
dc.identifier.uri.none.fl_str_mv |
http://repository.urosario.edu.co//handle/10336/13223 |
url |
https://doi.org/10.48713/10336_13223 http://repository.urosario.edu.co//handle/10336/13223 |
dc.language.iso.none.fl_str_mv |
spa |
language |
spa |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Universidad del Rosario |
dc.publisher.department.spa.fl_str_mv |
Facultad de medicina |
dc.publisher.program.none.fl_str_mv |
Especialización en Epidemiología |
institution |
Universidad del Rosario |
dc.source.bibliographicCitation.none.fl_str_mv |
Blanco O, Cantillo A, Rivera J. Enfoque actual del cáncer gástrico. Rev Médicas UIS [Internet]. 2013;26(1):59–70. Available from: http://dialnet.unirioja.es/servlet/articulo?codigo=4545655 Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11. Lyon, France: International Agency for Research on Cancer; 2013. 2012. Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ CK (eds). Cancer Statistics Review, 1975-2013, National Cancer Institute. SEER [Internet]. 2013;1–89. Available from: http://seer.cancer.gov/csr/1975_2013/ Alvarado Tolentino C, Venegas Ojeda D. Sobrevida de pacientes con cáncer gástrico en el Perú , 2009 – 2010. Rev Panam Salud Pública. 2015;37(3):133–9. Kim HS, Lee H, Jeung HC, Noh SH, Chung HC, Roh JK, et al. Advanced detection of recent changing trends in gastric cancer survival: Up-to-date comparison by period analysis. Jpn J Clin Oncol. 2011;41(12):1344–50. Colquhoun A, Arnold M, Ferlay J, Goodman KJ, Forman D, Soerjomataram I. Global patterns of cardia and non-cardia gastric cancer incidence in 2012. Gut [Internet]. 2015;64(12):1881–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25748648 Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin [Internet]. 2002;55(2):74–108. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15761078 Elena D, Duque D. Cáncer gástrico en colombia entre 2000 y 2009. 2012;1–52. Correa P. Gastric Cancer. Overview. Gastroenterol Clin North Am [Internet]. Elsevier Inc; 2013;42(2):211–7. Available from: http://dx.doi.org/10.1016/j.gtc.2013.01.002 Fenoglio-Preiser C, Carneiro F, Correa P, Guilford P, Lambert R, Megraud F. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Digestive System. IARCPress Lyon [Internet]. 2000;1(3):1–314. Available from: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=11829087&retmode=ref&cmd=prlinks%5Cnpapers3://publication/uuid/C02A82F1-823F-4021-94A7-4D1CE0C4214D Cutsem E Van, Sagaert X, Topal B, Haustermans K, Prenen H. Seminar Gastric cancer. Lancet. 2016;6736(9):477–90. Washington K. 7th Edition of the AJCC Cancer Staging Manual: Stomach. Ann Surg Oncol. 2010;3077–9. Lauren P. THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. Acta Pathol Microbiol Scand [Internet]. 1965;64:31–49. Available from: https://www.ncbi.nlm.nih.gov/pubmed/14320675 Bosman, F.T., Carneiro, F., Hruban, R.H. WHO classification of tumours of the digestive system, Fourth Edition. Volume 3 [Internet]. 2010. 44–58 p. Available from: https://www.ncbi.nlm.nih.gov/nlmcatalog/101553728 Fearon ER. Molecular Genetics of Colorectal Cancer. 1994;768(ii):101–10. Muñoz N. MI. Histological types of gastric cancer and its relationship with intestinal metaplasia. Recent Results Cancer Res [Internet]. 1972;39:99–105. Available from: https://www.ncbi.nlm.nih.gov/pubmed/?term=Histological+types+of+gastric+cancer+and+its+relationship+with+intestinal+metaplasia. McDonald SAC, Greaves LC, Gutierrez-Gonzalez L, Rodriguez-Justo M, Deheragoda M, Leedham SJ, et al. Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells. Gastroenterology. 2008;134(2):500–10. Correa P. Human Gastric Carcinogenesis : A Multistep and Multifactorial Process First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992;52(18):6735–40. Correa P, Haenszel W, Cuello C, Zavala D, Fontham E, Zarama G, et al. Gastric Precancerous Process in a High Risk Population : Cohort Follow-up. Cancer Res. 1990;50:4737–40. Wang F, Meng W, Wang B, Qiao L. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. Elsevier Ireland Ltd; 2014;345(2):196–202. Correa P. A Human Model of Gastric Carcinogenesis. CANCER Res Perspect Cancer Res. 1988;48(13):3554–60. Quante M, Tu SP, Tomita H, Gonda T, Wang SSW, Takashi S, et al. Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth. Cancer Cell. Elsevier Inc.; 2011;19(2):257–72. Jiang L, Gonda TA, Gamble M V., Salas M, Seshan V, Tu S, et al. Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Res. 2008;68(23):9900–8. Okines A, Verheij M, Allum W, Cunningham D, Cervantes A. clinical practice guidelines Gastric cancer : ESMO Clinical Practice Guidelines for diagnosis , treatment and follow-up clinical practice guidelines. 2010;21(Supplement 5):50–4. Marqués-Lespier JM, González-Pons M, Cruz-Correa M. Current Perspectives on Gastric Cancer. 2016;45:413–28. Sano T, Kodera Y. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14(2):101–12. Sobin L, Gospodarowicz M WC (eds). TNM : classification of malignant tumours. 2009. 1-310 p. Waddell T, Verheij M, Allum W, Cunningham D, Cervantes A, Arnold D. Gastric cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol. Elsevier Ltd; 2014;40(5):584–91. Institute NC. NCI dictionary of cancer terms. 2011; Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=44070 Canción HK, Lee H, Jeung HC, Noh SH. Detección avanzada de cambio de las tendencias recientes en el cáncer gástrico supervivencia : Hasta al fecha Comparación de Análisis Periodo. 2016;1–11. Heise K, Bertran E, Andia ME, Ferreccio C. Incidence and survival of stomach cancer in a high-risk population of Chile. World J Gastroenterol. 2009;15(15):1854–62. Zheng L, Wu C, Xi P, Zhu M, Zhang L, Chen S, et al. The survival and the long-term trends of patients with gastric cancer in Shanghai, China. BMC Cancer [Internet]. 2014;14:300. Available from: http://www.biomedcentral.com/content/pdf/1471-2407-14-300.pdf Oscar Tapia E, Miguel Villaseca H, Enrique Bellolio J, Juan Carlos Araya O, Juan Carlos Roa S. Cancer gastrico sin compromiso ganglionar linfatico: Caracteristicas demografico-patologicas y factores pronosticos. Rev Med Chil. 2011;139(4):432–8. Medrano-Guzmán R, Valencia-Mercado D, Luna-Castillo M, García-Ríos LE, González-Rodríguez D. Factores pronóstico de sobrevida en adenocarcinoma gástrico avanzado resecable. Cir Cir [Internet]. Academia Mexicana de Cirugía A.C.; 2016;84(6):469–76. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0009741116000141 Lin W, Sun J, Chang S, Wu P. Factors Predicting Survival of Patients with Gastric Cancer. asian pacific J cancer Prev. 2014;15:5835–8. Rodríguez Fernández Z, Piña Prieto L, Manzano Horta E. Factores pronósticos relacionados con el cáncer gástrico. Rev Cuba Cirugía. 2011;50(3):363–87. Cancer IA for R on. Mechanisms of Carcinogenesis: contributions of molecular epidemiology [Internet]. IARC Scientific Publications. 2004 [cited 2017 Feb 4]. 450 p. Available from: http://publications.iarc.fr/Book-And-Report-Series/Iarc-Scientific-Publications/Mechanisms-Of-Carcinogenesis-Contributions-Of-Molecular-Epidemiology-2004 Duharte B. Función Del Sistema Inmune En La Defensa Contra Tumores Malignos. Medsan. 2003;7(2):75–88. Urich H. Handbuch Der Speziellen Pathologischen Anatomie Und Histologie. Vol. 34, Journal of neurology, neurosurgery, and psychiatry. Berlin : J. Springer,; 1971. 111 p. Saragoni L. Upgrading the definition of early gastric cancer: better staging means more appropriate treatment. Cancer Biol Med [Internet]. 2015;12(4):355–61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26779372%5Cnhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4706527 Park J, Ryu W, Kim J, Park S, Kim C, Mok Y. Prognostic Factors for A dvanced G astric C ancer : Stage- stratified A nalysis of Patients w ho U nderw ent C urative Resection. Cancer Res. 2006;38(January 1993):13–8. A DGA, G OL, B JM, H MZ, S LM, H HS, et al. Patrón pronóstico de invasión serosa ( S2 ) en carcinoma gástrico. Rev Chil Cirugía. 2002;54. Hartgrink H, Van De Velde C, Putter H, Bonenkamp J, Klein Kranenbarg E, Songun I, et al. Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial. J Clin Oncol. 2004;22(11):2069–77. Wild CP. Preventable exposures associated with human cancer. Cancer Res [Internet]. 2013;73(8):1–13. Available from: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L71349164 World Health Organization. WHO Global Report: Mortality Attributable To Tobacco [Internet]. Who Global Report. 2012. Available from: http://www.who.int/tobacco/publications/surveillance/fact_sheet_mortality_report.pd Rodgman A, Perfetti TA. The Chemical Components of Tobacco and Tobacco Smoke. Second Edi. Taylor & Francis Group, editor. Vol. 1, Statewide Agricultural Land Use Baseline 2015. 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742: CRC Press; 2013. IARC Working group. Tobacco Smoking. Monographs. 2010;2002:43–211. LaTorre, G;Chiaradia, G;Gianfagna, F; De Lauretis, A; Boccia, S; Mannocci, A; Ricciardi W. Smoking status and gastric cancer risk:an update meta-analysis of case-control studies published in the past ten years. Tumori. 2009;Jan-Feb 95(1):13–22. Marco C, Oms D, De I. Control y prevención de productos de tabaco sin humo y cigarrillos electrónicos. 2010;15–20. Sponsiello-Wang Z, Weitkunat R, Lee PN. Systematic review of the relation between smokeless tobacco and cancer of the pancreas in Europe and North America. BMC Cancer [Internet]. 2008;8:356. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2612688&tool=pmcentrez&rendertype=abstract Boffetta P, Aagnes B, Weiderpass E, Andersen A. Smokeless tobacco use and risk of cancer of the pancreas and other organs. Int J cancer [Internet]. 2005 May 10 [cited 2016 Aug 2];114(6):992–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15645430 IARC Handbooks of Cancer Prevention, Vol. 8. Fruits and Veg- etables. Lyon FIP 2003. Definitions and classifications for fruit and vegetables. IARCPress Lyon. 2003; Chyou P, Nomura AMY, Hankin JH, Chyou P, Nomura AMY, Hankin JH, et al. A Case-Cohort Study of Diet and Stomach Cancer. 1990;(25):7501–4. Vainio H, Bianchini F, International Agency for Research on Cancer Working Group on the Evaluation of Cancer-Preventive Agents. Cancer-preventive effects. IARC Handbooks Cancer Prev Weight Control Phys Act. 2002;145–51. Kim HJ, Lim SY, Lee J-S, Park S, Shin A, Choi BY, et al. Fresh and pickled vegetable consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci [Internet]. 2010 Feb [cited 2016 May 10];101(2):508–16. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19860848 PubChem CN de I de BB de datos. betacaroteno | C40H56 - PubChem [Internet]. nal of Molecular Structure-Theochem. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5280489#section=Top Blot WJ, Li JY, Taylor PR, Guo W, Dawsey S, Wang GQ, et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J Natl Cancer Inst [Internet]. 1993 Sep 15 [cited 2016 Aug 8];85(18):1483–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8360931 PubChem CN de I de BB de datos. cloruro de sodio | ClNa - PubChem [Internet]. nal of Molecular Structure-Theochem. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5234#section=Top Takahashi M, Hasegawa R. Enhancing effects of dietary salt on both initiation and promotion stages of rat gastric carcinogenesis. Princess Takamatsu Symp [Internet]. 1985 [cited 2016 Aug 9];16:169–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3916194 Xu Y, Yan Y, Hou M, Liu Y. NaCl pretreatment attenuates H.pylori-induced DNA damage and exacerbates proliferation of gastric epithelial cells (GES-1). Infect Agent Cancer. 2015;10:4–12. Ops. Alimentos, nutricion, AF y prevencion del Cancer: una perspectiva mundial. 2007;1–20. Available from: http://www.paho.org/hq/index.php?option=com_docman&task=doc_view&gid=13330&Itemid Ward MH, Cross AJ, Abnet CC, Sinha R, Markin RS, Weisenburger DD. Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach. Eur J Cancer Prev. 2012;21(2):134–8. Zhu H, Yang X, Zhang C, Zhu C, Tao G, Zhao L, et al. Red and Processed Meat Intake Is Associated with Higher Gastric Cancer Risk: A Meta-Analysis of Epidemiological Observational Studies. PLoS One. 2013;8(8). Gonzalez CA, Jakszyn P, Pera G, Agudo A, Bingham S, Palli D, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst. 2006;98(5):345–54. Babor T, Campbell R, Room R, Saunders J. Glosario de Términos de Alcohol y Drogas. World Health [Internet]. 1994;66. Available from: http://www.who.int/substance_abuse/terminology/lexicon_alcohol_drugs_spanish.pdf Tramacere I, Negri E, Pelucchi C, Bagnardi V, Rota M, Scotti L, et al. A meta-analysis on alcohol drinking and gastric cancer risk. Ann Oncol. 2012;23(1):28–36. Chen Y, Liu L, Wang X, Wang J, Yan Z, Cheng J, et al. Body mass index and risk of gastric cancer: a meta-analysis of a population with more than ten million from 24 prospective studies. Cancer Epidemiol Biomarkers Prev [Internet]. 2013;(Ci):1395–409. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23697611 Lin X-J, Wang C-P, Liu X-D, Yan K-K, Li S, Bao H-H, et al. Body Mass Index and Risk of Gastric Cancer: A Meta-analysis. Jpn J Clin Oncol [Internet]. 2014;44(June):783–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24951830 World Health Organisation. Global Database on Body Mass Index [Internet]. World Health Organization (WHO). 2016. Available from: http://apps.who.int/bmi/index.jsp Aird I, Bentall H, Robert J, Roberts J. A Relationship Between Cancer Of Stomach And The Abo Blood Groups. Br Med J [Internet]. 1953;1(4814):799–801. Available from: http://www.jstor.org/stable/20310866%5Cnpapers2://publication/uuid/CBF60F56-B5D1-4980-B83C-A289B374D844 Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, et al. Risk of gastric cancer and peptic ulcers in relation to ABO blood type: A cohort study. Am J Epidemiol. 2010;172(11):1280–5. Song HR, Shin MH, Kim HN, Piao JM, Choi JS, Hwang JE, et al. Sex-specific differences in the association between ABO genotype and gastric cancer risk in a Korean population. Gastric Cancer. 2013;16(2):254–60. Yaghoobi M, Bijarchi R, Narod SA. Family history and the risk of gastric cancer. Br J Cancer [Internet]. Nature Publishing Group; 2010;102(2):237–42. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2816643&tool=pmcentrez&rendertype=abstract Zanghieri G, Gregorio C Di, Sacchetti C, Fante R, Sassatelli R, Cannizzo G, et al. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry. Cancer [Internet]. 1990;66(9):2047–51. Available from: http://dx.doi.org/10.1002/1097-0142(19901101)66:9%3C2047::AID-CNCR2820660934%3E3.0.CO%5Cn2-G Brenner H, Arndt V, Stürmer T, Stegmaier C, Ziegler H, Dhom G. Individual and joint contribution of family history and Helicobacter pylori infection to the risk of gastric carcinoma. Cancer [Internet]. 2000 Jan 15 [cited 2016 Sep 26];88(2):274–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10640957 Leung WK, Ng EKW, Chan WY, Auyeung ACM, Chan K-F, Lam CCH, et al. Risk factors associated with the development of intestinal metaplasia in first-degree relatives of gastric cancer patients. Cancer Epidemiol Biomarkers Prev [Internet]. 2005;14(December):2982–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16365021 Dai YC, Tang ZP, Zhang YL. How to assess the severity of atrophic gastritis. World J Gastroenterol. 2011;17(13):1690–3. Yoshimura T, Shimoyama T, Tanaka M, Sasaki Y, Fukuda S, Munakata A. Gastric mucosal inflammation and epithelial cell turnover are associated with gastric cancer in patients with Helicobacter pylori infection. 2000;532–6. Vannella L, Lahner E, Annibale B. Risk for gastric neoplasias in patients with chronic atrophic gastritis: A critical reappraisal. World J Gastroenterol. 2012;18(12):1279–85. Wu AH, Tseng C-C, Bernstein L. Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma. Cancer [Internet]. 2003;98(5):940–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12942560 LAGERGREN, JESPER, BERGSTRÖM R. SYMPTOMATIC GASTROESOPHAGEAL REFLUX AS A RISK FACTOR FOR ESOPHAGEAL ADENOCARCINOMA. N Engl J Med. 1999;340:825–31. Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV / AIDS compared with ... Lancet. 2007;370(9447):59–67. Youlden DR, Baade PD. The relative risk of second primary cancers in Queensland , Australia : a retrospective cohort study. BMC Cancer [Internet]. BioMed Central Ltd; 2011;11(1):83. Available from: http://www.biomedcentral.com/1471-2407/11/83 Bastos A, Ferro A, Lunet N. Prevalencia de Helicobacter pylori infección por todo el mundo : una revisión sistemática de estudios de cobertura nacional Abstracto. 2016; De Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D, et al. Global burden of cancers attributable to infections in 2008: A review and synthetic analysis. Lancet Oncol [Internet]. Elsevier Ltd; 2012;13(6):607–15. Available from: http://dx.doi.org/10.1016/S1470-2045(12)70137-7 Organización Mundial de la Salud. Ciclo de vida [Internet]. Ministerio de Salud y Protección Social. 2016. Available from: https://www.minsalud.gov.co/proteccionsocial/Paginas/cicloVida.aspx |
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Juliao-Nacith, Haroldo Hernandoa763bd67-a966-46bb-9149-3e9ee7ce4b58-1Isaza Restrepo, Andrés3229856600Rubiano Bello, Fabián LeandroCubides Amézquita, Jenner RodrigoReyes Silva, Margarita MaríaEspecialista en Epidemiología (en Convenio con el CES)2eb24fa9-f041-477d-8d47-d9f916547905-15cb40d89-e1ef-4cd6-baa0-5d2bfc65e114-1b3c8ae51-ed89-412a-8056-16d61880d0dd-12017-04-03T19:19:56Z2017-04-03T19:19:56Z2016-11-282016El cáncer gástrico representa un problema de salud pública debido a su alta incidencia. La supervivencia de todos los tipos de cáncer en forma global se calcula en 68.9% a 5 años, en contraste con el cáncer gástrico donde la supervivencia alcanza el 32%. A nivell local algunos estudios han encontrado sobrevida a 5 años del 10,6% en contraposición con países donde se encuentran tasas de sobrevida del 48,5%. La toma de dato se realizó de los registros del servicio de patología y en las historias clínicas del Hospital Militar Central del personal diagnosticado con adenocarcinoma gástrico en el periodo entre 2012 y 2015. Se obtuvieron 98 registros, la media de edad fue 59,3 años (59,3±18,12). Por sexo la distribución fue hombres 74.5% y mujeres 25.5%; por tipo histológico intestinal 52%, difuso 39.8% y mixto 8.2%; Por estadios, el IV fue el más frecuente con 45.9%. La tasa de supervivencia global fue de 19%. La mediana de supervivencia global fue de 18.2 meses (IC del 95% de 11.5-24.8) y la tasa de supervivencia para menores de 60 años se estimó en 25% y para mayores de 60 años fue 24%, analizadas a 4 años. La tasa global de sobrevida fue de 19%, inferior a la reportada en países desarrollados, aunque la sobrevida para el primer y segundo año son similares a éstos, lo que se explica por un tratamiento adecuado pero un diagnóstico tardío, ya que el 77.5% de los pacientes de nuestro estudio estaban en estadios III y IV.Gastric cancer represents a public health problem because of its high incidence. Survival of all types of cancer globally is estimated at 68.9% at 5 years, in contrast to gastric cancer where survival only reaches 32%. In our sample, some studies have found a 5-year survival rate of 10.6% (29) as opposed to countries where survival rates are 48.5%. Data collection was done by searching the records of the pathology service and the medical histories of the Central Military of personnel diagnosed with gastric adenocarcinoma in the Period between 2012 and 2015. The mean age was 59.3 years (59,3±18,12). The gender distribution was in men 74.5% and women 25.5%; by intestinal histological type 52%, diffuse 39.8% and mixed 8.2%; by stages, IV was the most frequent with 45.9%. The overall survival rate was 19%. The median overall survival was 18.2 months (95% CI of 11.5-24.8) and the survival rate for those younger than 60 years was estimated at 25% and 24% for those over 60 years old, analyzed at 4 years.The overall survival rate was 19% for the 48-month study period, lower than that reported for developed countries (The United States for 29%). The survival for the first and second year is similar to that for the study period. It´s can be explained by adequate treatment but a late diagnosis, since 77.5% of the patients in our study were in stages III and IV.2019-08-01 06:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2019-04-03application/pdfhttps://doi.org/10.48713/10336_13223 http://repository.urosario.edu.co//handle/10336/13223spaUniversidad del RosarioFacultad de medicinaEspecialización en EpidemiologíaAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.http://purl.org/coar/access_right/c_abf2Blanco O, Cantillo A, Rivera J. Enfoque actual del cáncer gástrico. Rev Médicas UIS [Internet]. 2013;26(1):59–70. Available from: http://dialnet.unirioja.es/servlet/articulo?codigo=4545655Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11. Lyon, France: International Agency for Research on Cancer; 2013. 2012.Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ CK (eds). Cancer Statistics Review, 1975-2013, National Cancer Institute. SEER [Internet]. 2013;1–89. Available from: http://seer.cancer.gov/csr/1975_2013/Alvarado Tolentino C, Venegas Ojeda D. Sobrevida de pacientes con cáncer gástrico en el Perú , 2009 – 2010. Rev Panam Salud Pública. 2015;37(3):133–9.Kim HS, Lee H, Jeung HC, Noh SH, Chung HC, Roh JK, et al. Advanced detection of recent changing trends in gastric cancer survival: Up-to-date comparison by period analysis. Jpn J Clin Oncol. 2011;41(12):1344–50.Colquhoun A, Arnold M, Ferlay J, Goodman KJ, Forman D, Soerjomataram I. Global patterns of cardia and non-cardia gastric cancer incidence in 2012. Gut [Internet]. 2015;64(12):1881–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25748648Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin [Internet]. 2002;55(2):74–108. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15761078Elena D, Duque D. Cáncer gástrico en colombia entre 2000 y 2009. 2012;1–52.Correa P. Gastric Cancer. Overview. Gastroenterol Clin North Am [Internet]. Elsevier Inc; 2013;42(2):211–7. Available from: http://dx.doi.org/10.1016/j.gtc.2013.01.002Fenoglio-Preiser C, Carneiro F, Correa P, Guilford P, Lambert R, Megraud F. World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Digestive System. IARCPress Lyon [Internet]. 2000;1(3):1–314. Available from: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=11829087&retmode=ref&cmd=prlinks%5Cnpapers3://publication/uuid/C02A82F1-823F-4021-94A7-4D1CE0C4214DCutsem E Van, Sagaert X, Topal B, Haustermans K, Prenen H. Seminar Gastric cancer. Lancet. 2016;6736(9):477–90.Washington K. 7th Edition of the AJCC Cancer Staging Manual: Stomach. Ann Surg Oncol. 2010;3077–9.Lauren P. THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. Acta Pathol Microbiol Scand [Internet]. 1965;64:31–49. Available from: https://www.ncbi.nlm.nih.gov/pubmed/14320675Bosman, F.T., Carneiro, F., Hruban, R.H. WHO classification of tumours of the digestive system, Fourth Edition. Volume 3 [Internet]. 2010. 44–58 p. Available from: https://www.ncbi.nlm.nih.gov/nlmcatalog/101553728Fearon ER. Molecular Genetics of Colorectal Cancer. 1994;768(ii):101–10.Muñoz N. MI. Histological types of gastric cancer and its relationship with intestinal metaplasia. Recent Results Cancer Res [Internet]. 1972;39:99–105. Available from: https://www.ncbi.nlm.nih.gov/pubmed/?term=Histological+types+of+gastric+cancer+and+its+relationship+with+intestinal+metaplasia.McDonald SAC, Greaves LC, Gutierrez-Gonzalez L, Rodriguez-Justo M, Deheragoda M, Leedham SJ, et al. Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells. Gastroenterology. 2008;134(2):500–10.Correa P. Human Gastric Carcinogenesis : A Multistep and Multifactorial Process First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992;52(18):6735–40.Correa P, Haenszel W, Cuello C, Zavala D, Fontham E, Zarama G, et al. Gastric Precancerous Process in a High Risk Population : Cohort Follow-up. Cancer Res. 1990;50:4737–40.Wang F, Meng W, Wang B, Qiao L. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. Elsevier Ireland Ltd; 2014;345(2):196–202.Correa P. A Human Model of Gastric Carcinogenesis. CANCER Res Perspect Cancer Res. 1988;48(13):3554–60.Quante M, Tu SP, Tomita H, Gonda T, Wang SSW, Takashi S, et al. Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth. Cancer Cell. Elsevier Inc.; 2011;19(2):257–72.Jiang L, Gonda TA, Gamble M V., Salas M, Seshan V, Tu S, et al. Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Res. 2008;68(23):9900–8.Okines A, Verheij M, Allum W, Cunningham D, Cervantes A. clinical practice guidelines Gastric cancer : ESMO Clinical Practice Guidelines for diagnosis , treatment and follow-up clinical practice guidelines. 2010;21(Supplement 5):50–4.Marqués-Lespier JM, González-Pons M, Cruz-Correa M. Current Perspectives on Gastric Cancer. 2016;45:413–28.Sano T, Kodera Y. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14(2):101–12.Sobin L, Gospodarowicz M WC (eds). TNM : classification of malignant tumours. 2009. 1-310 p.Waddell T, Verheij M, Allum W, Cunningham D, Cervantes A, Arnold D. Gastric cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol. Elsevier Ltd; 2014;40(5):584–91.Institute NC. NCI dictionary of cancer terms. 2011; Available from: https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=44070Canción HK, Lee H, Jeung HC, Noh SH. Detección avanzada de cambio de las tendencias recientes en el cáncer gástrico supervivencia : Hasta al fecha Comparación de Análisis Periodo. 2016;1–11.Heise K, Bertran E, Andia ME, Ferreccio C. Incidence and survival of stomach cancer in a high-risk population of Chile. World J Gastroenterol. 2009;15(15):1854–62.Zheng L, Wu C, Xi P, Zhu M, Zhang L, Chen S, et al. The survival and the long-term trends of patients with gastric cancer in Shanghai, China. BMC Cancer [Internet]. 2014;14:300. Available from: http://www.biomedcentral.com/content/pdf/1471-2407-14-300.pdfOscar Tapia E, Miguel Villaseca H, Enrique Bellolio J, Juan Carlos Araya O, Juan Carlos Roa S. Cancer gastrico sin compromiso ganglionar linfatico: Caracteristicas demografico-patologicas y factores pronosticos. Rev Med Chil. 2011;139(4):432–8.Medrano-Guzmán R, Valencia-Mercado D, Luna-Castillo M, García-Ríos LE, González-Rodríguez D. Factores pronóstico de sobrevida en adenocarcinoma gástrico avanzado resecable. Cir Cir [Internet]. Academia Mexicana de Cirugía A.C.; 2016;84(6):469–76. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0009741116000141Lin W, Sun J, Chang S, Wu P. Factors Predicting Survival of Patients with Gastric Cancer. asian pacific J cancer Prev. 2014;15:5835–8.Rodríguez Fernández Z, Piña Prieto L, Manzano Horta E. Factores pronósticos relacionados con el cáncer gástrico. Rev Cuba Cirugía. 2011;50(3):363–87.Cancer IA for R on. Mechanisms of Carcinogenesis: contributions of molecular epidemiology [Internet]. IARC Scientific Publications. 2004 [cited 2017 Feb 4]. 450 p. Available from: http://publications.iarc.fr/Book-And-Report-Series/Iarc-Scientific-Publications/Mechanisms-Of-Carcinogenesis-Contributions-Of-Molecular-Epidemiology-2004Duharte B. Función Del Sistema Inmune En La Defensa Contra Tumores Malignos. Medsan. 2003;7(2):75–88.Urich H. Handbuch Der Speziellen Pathologischen Anatomie Und Histologie. Vol. 34, Journal of neurology, neurosurgery, and psychiatry. Berlin : J. Springer,; 1971. 111 p.Saragoni L. Upgrading the definition of early gastric cancer: better staging means more appropriate treatment. Cancer Biol Med [Internet]. 2015;12(4):355–61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26779372%5Cnhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4706527Park J, Ryu W, Kim J, Park S, Kim C, Mok Y. Prognostic Factors for A dvanced G astric C ancer : Stage- stratified A nalysis of Patients w ho U nderw ent C urative Resection. Cancer Res. 2006;38(January 1993):13–8.A DGA, G OL, B JM, H MZ, S LM, H HS, et al. Patrón pronóstico de invasión serosa ( S2 ) en carcinoma gástrico. Rev Chil Cirugía. 2002;54.Hartgrink H, Van De Velde C, Putter H, Bonenkamp J, Klein Kranenbarg E, Songun I, et al. Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial. J Clin Oncol. 2004;22(11):2069–77.Wild CP. Preventable exposures associated with human cancer. Cancer Res [Internet]. 2013;73(8):1–13. Available from: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L71349164World Health Organization. WHO Global Report: Mortality Attributable To Tobacco [Internet]. Who Global Report. 2012. Available from: http://www.who.int/tobacco/publications/surveillance/fact_sheet_mortality_report.pdRodgman A, Perfetti TA. The Chemical Components of Tobacco and Tobacco Smoke. Second Edi. Taylor & Francis Group, editor. Vol. 1, Statewide Agricultural Land Use Baseline 2015. 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742: CRC Press; 2013.IARC Working group. Tobacco Smoking. Monographs. 2010;2002:43–211.LaTorre, G;Chiaradia, G;Gianfagna, F; De Lauretis, A; Boccia, S; Mannocci, A; Ricciardi W. Smoking status and gastric cancer risk:an update meta-analysis of case-control studies published in the past ten years. Tumori. 2009;Jan-Feb 95(1):13–22.Marco C, Oms D, De I. Control y prevención de productos de tabaco sin humo y cigarrillos electrónicos. 2010;15–20.Sponsiello-Wang Z, Weitkunat R, Lee PN. Systematic review of the relation between smokeless tobacco and cancer of the pancreas in Europe and North America. BMC Cancer [Internet]. 2008;8:356. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2612688&tool=pmcentrez&rendertype=abstractBoffetta P, Aagnes B, Weiderpass E, Andersen A. Smokeless tobacco use and risk of cancer of the pancreas and other organs. Int J cancer [Internet]. 2005 May 10 [cited 2016 Aug 2];114(6):992–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15645430IARC Handbooks of Cancer Prevention, Vol. 8. Fruits and Veg- etables. Lyon FIP 2003. Definitions and classifications for fruit and vegetables. IARCPress Lyon. 2003;Chyou P, Nomura AMY, Hankin JH, Chyou P, Nomura AMY, Hankin JH, et al. A Case-Cohort Study of Diet and Stomach Cancer. 1990;(25):7501–4.Vainio H, Bianchini F, International Agency for Research on Cancer Working Group on the Evaluation of Cancer-Preventive Agents. Cancer-preventive effects. IARC Handbooks Cancer Prev Weight Control Phys Act. 2002;145–51.Kim HJ, Lim SY, Lee J-S, Park S, Shin A, Choi BY, et al. Fresh and pickled vegetable consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci [Internet]. 2010 Feb [cited 2016 May 10];101(2):508–16. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19860848PubChem CN de I de BB de datos. betacaroteno | C40H56 - PubChem [Internet]. nal of Molecular Structure-Theochem. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5280489#section=TopBlot WJ, Li JY, Taylor PR, Guo W, Dawsey S, Wang GQ, et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J Natl Cancer Inst [Internet]. 1993 Sep 15 [cited 2016 Aug 8];85(18):1483–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8360931PubChem CN de I de BB de datos. cloruro de sodio | ClNa - PubChem [Internet]. nal of Molecular Structure-Theochem. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5234#section=TopTakahashi M, Hasegawa R. Enhancing effects of dietary salt on both initiation and promotion stages of rat gastric carcinogenesis. Princess Takamatsu Symp [Internet]. 1985 [cited 2016 Aug 9];16:169–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3916194Xu Y, Yan Y, Hou M, Liu Y. NaCl pretreatment attenuates H.pylori-induced DNA damage and exacerbates proliferation of gastric epithelial cells (GES-1). Infect Agent Cancer. 2015;10:4–12.Ops. Alimentos, nutricion, AF y prevencion del Cancer: una perspectiva mundial. 2007;1–20. Available from: http://www.paho.org/hq/index.php?option=com_docman&task=doc_view&gid=13330&ItemidWard MH, Cross AJ, Abnet CC, Sinha R, Markin RS, Weisenburger DD. Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach. Eur J Cancer Prev. 2012;21(2):134–8.Zhu H, Yang X, Zhang C, Zhu C, Tao G, Zhao L, et al. Red and Processed Meat Intake Is Associated with Higher Gastric Cancer Risk: A Meta-Analysis of Epidemiological Observational Studies. PLoS One. 2013;8(8).Gonzalez CA, Jakszyn P, Pera G, Agudo A, Bingham S, Palli D, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst. 2006;98(5):345–54.Babor T, Campbell R, Room R, Saunders J. Glosario de Términos de Alcohol y Drogas. World Health [Internet]. 1994;66. Available from: http://www.who.int/substance_abuse/terminology/lexicon_alcohol_drugs_spanish.pdfTramacere I, Negri E, Pelucchi C, Bagnardi V, Rota M, Scotti L, et al. A meta-analysis on alcohol drinking and gastric cancer risk. Ann Oncol. 2012;23(1):28–36.Chen Y, Liu L, Wang X, Wang J, Yan Z, Cheng J, et al. Body mass index and risk of gastric cancer: a meta-analysis of a population with more than ten million from 24 prospective studies. Cancer Epidemiol Biomarkers Prev [Internet]. 2013;(Ci):1395–409. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23697611Lin X-J, Wang C-P, Liu X-D, Yan K-K, Li S, Bao H-H, et al. Body Mass Index and Risk of Gastric Cancer: A Meta-analysis. Jpn J Clin Oncol [Internet]. 2014;44(June):783–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24951830World Health Organisation. Global Database on Body Mass Index [Internet]. World Health Organization (WHO). 2016. Available from: http://apps.who.int/bmi/index.jspAird I, Bentall H, Robert J, Roberts J. A Relationship Between Cancer Of Stomach And The Abo Blood Groups. Br Med J [Internet]. 1953;1(4814):799–801. Available from: http://www.jstor.org/stable/20310866%5Cnpapers2://publication/uuid/CBF60F56-B5D1-4980-B83C-A289B374D844Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, et al. Risk of gastric cancer and peptic ulcers in relation to ABO blood type: A cohort study. Am J Epidemiol. 2010;172(11):1280–5.Song HR, Shin MH, Kim HN, Piao JM, Choi JS, Hwang JE, et al. Sex-specific differences in the association between ABO genotype and gastric cancer risk in a Korean population. Gastric Cancer. 2013;16(2):254–60.Yaghoobi M, Bijarchi R, Narod SA. Family history and the risk of gastric cancer. Br J Cancer [Internet]. Nature Publishing Group; 2010;102(2):237–42. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2816643&tool=pmcentrez&rendertype=abstractZanghieri G, Gregorio C Di, Sacchetti C, Fante R, Sassatelli R, Cannizzo G, et al. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry. Cancer [Internet]. 1990;66(9):2047–51. Available from: http://dx.doi.org/10.1002/1097-0142(19901101)66:9%3C2047::AID-CNCR2820660934%3E3.0.CO%5Cn2-GBrenner H, Arndt V, Stürmer T, Stegmaier C, Ziegler H, Dhom G. Individual and joint contribution of family history and Helicobacter pylori infection to the risk of gastric carcinoma. Cancer [Internet]. 2000 Jan 15 [cited 2016 Sep 26];88(2):274–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10640957Leung WK, Ng EKW, Chan WY, Auyeung ACM, Chan K-F, Lam CCH, et al. Risk factors associated with the development of intestinal metaplasia in first-degree relatives of gastric cancer patients. Cancer Epidemiol Biomarkers Prev [Internet]. 2005;14(December):2982–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16365021Dai YC, Tang ZP, Zhang YL. How to assess the severity of atrophic gastritis. World J Gastroenterol. 2011;17(13):1690–3.Yoshimura T, Shimoyama T, Tanaka M, Sasaki Y, Fukuda S, Munakata A. Gastric mucosal inflammation and epithelial cell turnover are associated with gastric cancer in patients with Helicobacter pylori infection. 2000;532–6.Vannella L, Lahner E, Annibale B. Risk for gastric neoplasias in patients with chronic atrophic gastritis: A critical reappraisal. World J Gastroenterol. 2012;18(12):1279–85.Wu AH, Tseng C-C, Bernstein L. Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma. Cancer [Internet]. 2003;98(5):940–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12942560LAGERGREN, JESPER, BERGSTRÖM R. SYMPTOMATIC GASTROESOPHAGEAL REFLUX AS A RISK FACTOR FOR ESOPHAGEAL ADENOCARCINOMA. N Engl J Med. 1999;340:825–31.Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV / AIDS compared with ... Lancet. 2007;370(9447):59–67.Youlden DR, Baade PD. The relative risk of second primary cancers in Queensland , Australia : a retrospective cohort study. BMC Cancer [Internet]. BioMed Central Ltd; 2011;11(1):83. Available from: http://www.biomedcentral.com/1471-2407/11/83Bastos A, Ferro A, Lunet N. Prevalencia de Helicobacter pylori infección por todo el mundo : una revisión sistemática de estudios de cobertura nacional Abstracto. 2016;De Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D, et al. Global burden of cancers attributable to infections in 2008: A review and synthetic analysis. Lancet Oncol [Internet]. Elsevier Ltd; 2012;13(6):607–15. Available from: http://dx.doi.org/10.1016/S1470-2045(12)70137-7Organización Mundial de la Salud. Ciclo de vida [Internet]. Ministerio de Salud y Protección Social. 2016. 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