The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
Several sources of evidence indicate that exercise during and after breast cancer could positively modulate the tumor microenvironment. This meta-analysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. We searched for randomized controlle...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2016
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/23634
- Acceso en línea:
- https://doi.org/10.1158/1055-9965.EPI-15-1061
https://repository.urosario.edu.co/handle/10336/23634
- Palabra clave:
- C reactive protein
Interleukin 10
Interleukin 2
Interleukin 6
Interleukin 8
Tumor necrosis factor alpha
Autacoid
C reactive protein
Interleukin 10
Interleukin 6
Aerobic exercise
Breast cancer
Breast carcinogenesis
Cancer survivor
Chronic inflammation
Evidence based practice
Exercise
Human
Inflammation
Mediator release
Meta analysis
Priority journal
Protein blood level
Randomized controlled trial (topic)
Resistance training
Review
Systematic review
Tai Chi
Tumor microenvironment
Yoga
Blood
Breast tumor
Cancer survivor
Enzyme linked immunosorbent assay
Exercise
Female
Kinesiotherapy
Middle aged
Mortality
Physiology
Procedures
Regression analysis
Breast Neoplasms
C-Reactive Protein
Cancer Survivors
Enzyme-Linked Immunosorbent Assay
Exercise
Exercise Therapy
Female
Humans
Inflammation Mediators
Interleukin-10
Interleukin-6
Middle Aged
Randomized Controlled Trials as Topic
Regression Analysis
Human
human
human
IL10 protein
IL6 protein
Physical Conditioning
- Rights
- License
- Abierto (Texto Completo)
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dc.title.spa.fl_str_mv |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
title |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
spellingShingle |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis C reactive protein Interleukin 10 Interleukin 2 Interleukin 6 Interleukin 8 Tumor necrosis factor alpha Autacoid C reactive protein Interleukin 10 Interleukin 6 Aerobic exercise Breast cancer Breast carcinogenesis Cancer survivor Chronic inflammation Evidence based practice Exercise Human Inflammation Mediator release Meta analysis Priority journal Protein blood level Randomized controlled trial (topic) Resistance training Review Systematic review Tai Chi Tumor microenvironment Yoga Blood Breast tumor Cancer survivor Enzyme linked immunosorbent assay Exercise Female Kinesiotherapy Middle aged Mortality Physiology Procedures Regression analysis Breast Neoplasms C-Reactive Protein Cancer Survivors Enzyme-Linked Immunosorbent Assay Exercise Exercise Therapy Female Humans Inflammation Mediators Interleukin-10 Interleukin-6 Middle Aged Randomized Controlled Trials as Topic Regression Analysis Human human human IL10 protein IL6 protein Physical Conditioning |
title_short |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
title_full |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
title_fullStr |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
title_full_unstemmed |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
title_sort |
The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis |
dc.subject.keyword.spa.fl_str_mv |
C reactive protein Interleukin 10 Interleukin 2 Interleukin 6 Interleukin 8 Tumor necrosis factor alpha Autacoid C reactive protein Interleukin 10 Interleukin 6 Aerobic exercise Breast cancer Breast carcinogenesis Cancer survivor Chronic inflammation Evidence based practice Exercise Human Inflammation Mediator release Meta analysis Priority journal Protein blood level Randomized controlled trial (topic) Resistance training Review Systematic review Tai Chi Tumor microenvironment Yoga Blood Breast tumor Cancer survivor Enzyme linked immunosorbent assay Exercise Female Kinesiotherapy Middle aged Mortality Physiology Procedures Regression analysis Breast Neoplasms C-Reactive Protein Cancer Survivors Enzyme-Linked Immunosorbent Assay Exercise Exercise Therapy Female Humans Inflammation Mediators Interleukin-10 Interleukin-6 Middle Aged Randomized Controlled Trials as Topic Regression Analysis |
topic |
C reactive protein Interleukin 10 Interleukin 2 Interleukin 6 Interleukin 8 Tumor necrosis factor alpha Autacoid C reactive protein Interleukin 10 Interleukin 6 Aerobic exercise Breast cancer Breast carcinogenesis Cancer survivor Chronic inflammation Evidence based practice Exercise Human Inflammation Mediator release Meta analysis Priority journal Protein blood level Randomized controlled trial (topic) Resistance training Review Systematic review Tai Chi Tumor microenvironment Yoga Blood Breast tumor Cancer survivor Enzyme linked immunosorbent assay Exercise Female Kinesiotherapy Middle aged Mortality Physiology Procedures Regression analysis Breast Neoplasms C-Reactive Protein Cancer Survivors Enzyme-Linked Immunosorbent Assay Exercise Exercise Therapy Female Humans Inflammation Mediators Interleukin-10 Interleukin-6 Middle Aged Randomized Controlled Trials as Topic Regression Analysis Human human human IL10 protein IL6 protein Physical Conditioning |
dc.subject.keyword.eng.fl_str_mv |
Human human human IL10 protein IL6 protein Physical Conditioning |
description |
Several sources of evidence indicate that exercise during and after breast cancer could positively modulate the tumor microenvironment. This meta-analysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. We searched for randomized controlled trials published from January 1990 to March 2014. An inverse variance method of meta-analysis was performed using a random effects model in the presence of statistical heterogeneity. Eight high-quality trials (n = 478) were included. Exercise improved the serum concentrations of IL6 [weighted mean difference (WMD) = -0.55 pg/mL; 95% confidence interval (CI), -1.02 to -0.09], TNF? (WMD = -0.64 pg/mL; 95%CI, -1.21 to -0.06), IL8(MD= -0.49 pg/mL; 95% CI, -0.89 to -0.09), and IL2 (WMD = 1.03 pg/mL; 95% CI, 0.40 to 1.67). No significant differences were found in the serum concentrations of C-reactive protein (WMD = -0.15; 95% CI, -0.56 to 0.25) or IL10 (WMD = 0.41; 95% CI, -0.18 to 1.02). Exercise training positively modulates chronic low-grade inflammation in women with breast cancer, which may impact upon carcinogenic mechanisms and the tumor microenvironment. These findings align with the other positive effects of exercise for breast cancer survivors, reinforcing the appropriateness of exercise prescription in this population. © 2016 American Association for Cancer Research. |
publishDate |
2016 |
dc.date.created.spa.fl_str_mv |
2016 |
dc.date.accessioned.none.fl_str_mv |
2020-05-26T00:03:51Z |
dc.date.available.none.fl_str_mv |
2020-05-26T00:03:51Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1158/1055-9965.EPI-15-1061 |
dc.identifier.issn.none.fl_str_mv |
10559965 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/23634 |
url |
https://doi.org/10.1158/1055-9965.EPI-15-1061 https://repository.urosario.edu.co/handle/10336/23634 |
identifier_str_mv |
10559965 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
1017 |
dc.relation.citationIssue.none.fl_str_mv |
No. 7 |
dc.relation.citationStartPage.none.fl_str_mv |
1009 |
dc.relation.citationTitle.none.fl_str_mv |
Cancer Epidemiology Biomarkers and Prevention |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 25 |
dc.relation.ispartof.spa.fl_str_mv |
Cancer Epidemiology Biomarkers and Prevention, ISSN:10559965, Vol.25, No.7 (2016); pp. 1009-1017 |
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American Association for Cancer Research Inc. |
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Universidad del Rosario |
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fe9c32f1-4441-41f8-9974-baefba3cb250-181e2849c-2b1c-4e7e-a7b8-58a77f57d076-1b3c37ea2-bb71-4010-a7b6-4f366c598d21-1e9107d61-2df2-4735-9604-6cf8847ff12c-117ec8d64-3341-4564-9ba6-4593836583de-1d6f25b4b-6535-4bc0-9e9f-63c44ef651f6-1945181836002020-05-26T00:03:51Z2020-05-26T00:03:51Z2016Several sources of evidence indicate that exercise during and after breast cancer could positively modulate the tumor microenvironment. This meta-analysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. We searched for randomized controlled trials published from January 1990 to March 2014. An inverse variance method of meta-analysis was performed using a random effects model in the presence of statistical heterogeneity. Eight high-quality trials (n = 478) were included. Exercise improved the serum concentrations of IL6 [weighted mean difference (WMD) = -0.55 pg/mL; 95% confidence interval (CI), -1.02 to -0.09], TNF? (WMD = -0.64 pg/mL; 95%CI, -1.21 to -0.06), IL8(MD= -0.49 pg/mL; 95% CI, -0.89 to -0.09), and IL2 (WMD = 1.03 pg/mL; 95% CI, 0.40 to 1.67). No significant differences were found in the serum concentrations of C-reactive protein (WMD = -0.15; 95% CI, -0.56 to 0.25) or IL10 (WMD = 0.41; 95% CI, -0.18 to 1.02). Exercise training positively modulates chronic low-grade inflammation in women with breast cancer, which may impact upon carcinogenic mechanisms and the tumor microenvironment. These findings align with the other positive effects of exercise for breast cancer survivors, reinforcing the appropriateness of exercise prescription in this population. © 2016 American Association for Cancer Research.application/pdfhttps://doi.org/10.1158/1055-9965.EPI-15-106110559965https://repository.urosario.edu.co/handle/10336/23634engAmerican Association for Cancer Research Inc.1017No. 71009Cancer Epidemiology Biomarkers and PreventionVol. 25Cancer Epidemiology Biomarkers and Prevention, ISSN:10559965, Vol.25, No.7 (2016); pp. 1009-1017https://www.scopus.com/inward/record.uri?eid=2-s2.0-84977126612&doi=10.1158%2f1055-9965.EPI-15-1061&partnerID=40&md5=bf82def820f4eb893f35872bd94665dbAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURC reactive proteinInterleukin 10Interleukin 2Interleukin 6Interleukin 8Tumor necrosis factor alphaAutacoidC reactive proteinInterleukin 10Interleukin 6Aerobic exerciseBreast cancerBreast carcinogenesisCancer survivorChronic inflammationEvidence based practiceExerciseHumanInflammationMediator releaseMeta analysisPriority journalProtein blood levelRandomized controlled trial (topic)Resistance trainingReviewSystematic reviewTai ChiTumor microenvironmentYogaBloodBreast tumorCancer survivorEnzyme linked immunosorbent assayExerciseFemaleKinesiotherapyMiddle agedMortalityPhysiologyProceduresRegression analysisBreast NeoplasmsC-Reactive ProteinCancer SurvivorsEnzyme-Linked Immunosorbent AssayExerciseExercise TherapyFemaleHumansInflammation MediatorsInterleukin-10Interleukin-6Middle AgedRandomized Controlled Trials as TopicRegression AnalysisHumanhumanhumanIL10 proteinIL6 proteinPhysical ConditioningThe effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysisarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Meneses-Echávez, Jose FCorrea-Bautista, Jorge EGonzález-Jiménez, EmilioSchmidt Río-Valle, JacquelineElkins, Mark RLobelo, FelipeRamírez-Vélez, RobinsonORIGINAL1009-full.pdfapplication/pdf624038https://repository.urosario.edu.co/bitstreams/443c9720-e515-4017-b965-d466fe0b6aa7/downloadfd494dfeea3f1fa1d79049eccf443257MD51TEXT1009-full.pdf.txt1009-full.pdf.txtExtracted texttext/plain45873https://repository.urosario.edu.co/bitstreams/97ab541a-6464-4880-b255-18dde3304513/downloadc50f5b89c84c64cb7a58580ffba15776MD52THUMBNAIL1009-full.pdf.jpg1009-full.pdf.jpgGenerated Thumbnailimage/jpeg4636https://repository.urosario.edu.co/bitstreams/74783b68-3e3a-478b-afed-2f42ab017c77/download8c67d7345cbec2ca6b324f04a53f3b7eMD5310336/23634oai:repository.urosario.edu.co:10336/236342022-05-02 07:37:21.17508https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |