The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis

Several sources of evidence indicate that exercise during and after breast cancer could positively modulate the tumor microenvironment. This meta-analysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. We searched for randomized controlle...

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Autores:
Tipo de recurso:
Fecha de publicación:
2016
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23634
Acceso en línea:
https://doi.org/10.1158/1055-9965.EPI-15-1061
https://repository.urosario.edu.co/handle/10336/23634
Palabra clave:
C reactive protein
Interleukin 10
Interleukin 2
Interleukin 6
Interleukin 8
Tumor necrosis factor alpha
Autacoid
C reactive protein
Interleukin 10
Interleukin 6
Aerobic exercise
Breast cancer
Breast carcinogenesis
Cancer survivor
Chronic inflammation
Evidence based practice
Exercise
Human
Inflammation
Mediator release
Meta analysis
Priority journal
Protein blood level
Randomized controlled trial (topic)
Resistance training
Review
Systematic review
Tai Chi
Tumor microenvironment
Yoga
Blood
Breast tumor
Cancer survivor
Enzyme linked immunosorbent assay
Exercise
Female
Kinesiotherapy
Middle aged
Mortality
Physiology
Procedures
Regression analysis
Breast Neoplasms
C-Reactive Protein
Cancer Survivors
Enzyme-Linked Immunosorbent Assay
Exercise
Exercise Therapy
Female
Humans
Inflammation Mediators
Interleukin-10
Interleukin-6
Middle Aged
Randomized Controlled Trials as Topic
Regression Analysis
Human
human
human
IL10 protein
IL6 protein
Physical Conditioning
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
title The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
spellingShingle The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
C reactive protein
Interleukin 10
Interleukin 2
Interleukin 6
Interleukin 8
Tumor necrosis factor alpha
Autacoid
C reactive protein
Interleukin 10
Interleukin 6
Aerobic exercise
Breast cancer
Breast carcinogenesis
Cancer survivor
Chronic inflammation
Evidence based practice
Exercise
Human
Inflammation
Mediator release
Meta analysis
Priority journal
Protein blood level
Randomized controlled trial (topic)
Resistance training
Review
Systematic review
Tai Chi
Tumor microenvironment
Yoga
Blood
Breast tumor
Cancer survivor
Enzyme linked immunosorbent assay
Exercise
Female
Kinesiotherapy
Middle aged
Mortality
Physiology
Procedures
Regression analysis
Breast Neoplasms
C-Reactive Protein
Cancer Survivors
Enzyme-Linked Immunosorbent Assay
Exercise
Exercise Therapy
Female
Humans
Inflammation Mediators
Interleukin-10
Interleukin-6
Middle Aged
Randomized Controlled Trials as Topic
Regression Analysis
Human
human
human
IL10 protein
IL6 protein
Physical Conditioning
title_short The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
title_full The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
title_fullStr The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
title_full_unstemmed The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
title_sort The effect of exercise training on mediators of inflammation in breast cancer survivors: A systematic review with meta-analysis
dc.subject.keyword.spa.fl_str_mv C reactive protein
Interleukin 10
Interleukin 2
Interleukin 6
Interleukin 8
Tumor necrosis factor alpha
Autacoid
C reactive protein
Interleukin 10
Interleukin 6
Aerobic exercise
Breast cancer
Breast carcinogenesis
Cancer survivor
Chronic inflammation
Evidence based practice
Exercise
Human
Inflammation
Mediator release
Meta analysis
Priority journal
Protein blood level
Randomized controlled trial (topic)
Resistance training
Review
Systematic review
Tai Chi
Tumor microenvironment
Yoga
Blood
Breast tumor
Cancer survivor
Enzyme linked immunosorbent assay
Exercise
Female
Kinesiotherapy
Middle aged
Mortality
Physiology
Procedures
Regression analysis
Breast Neoplasms
C-Reactive Protein
Cancer Survivors
Enzyme-Linked Immunosorbent Assay
Exercise
Exercise Therapy
Female
Humans
Inflammation Mediators
Interleukin-10
Interleukin-6
Middle Aged
Randomized Controlled Trials as Topic
Regression Analysis
topic C reactive protein
Interleukin 10
Interleukin 2
Interleukin 6
Interleukin 8
Tumor necrosis factor alpha
Autacoid
C reactive protein
Interleukin 10
Interleukin 6
Aerobic exercise
Breast cancer
Breast carcinogenesis
Cancer survivor
Chronic inflammation
Evidence based practice
Exercise
Human
Inflammation
Mediator release
Meta analysis
Priority journal
Protein blood level
Randomized controlled trial (topic)
Resistance training
Review
Systematic review
Tai Chi
Tumor microenvironment
Yoga
Blood
Breast tumor
Cancer survivor
Enzyme linked immunosorbent assay
Exercise
Female
Kinesiotherapy
Middle aged
Mortality
Physiology
Procedures
Regression analysis
Breast Neoplasms
C-Reactive Protein
Cancer Survivors
Enzyme-Linked Immunosorbent Assay
Exercise
Exercise Therapy
Female
Humans
Inflammation Mediators
Interleukin-10
Interleukin-6
Middle Aged
Randomized Controlled Trials as Topic
Regression Analysis
Human
human
human
IL10 protein
IL6 protein
Physical Conditioning
dc.subject.keyword.eng.fl_str_mv Human
human
human
IL10 protein
IL6 protein
Physical Conditioning
description Several sources of evidence indicate that exercise during and after breast cancer could positively modulate the tumor microenvironment. This meta-analysis aimed to determine the effects of exercise training on mediators of inflammation in breast cancer survivors. We searched for randomized controlled trials published from January 1990 to March 2014. An inverse variance method of meta-analysis was performed using a random effects model in the presence of statistical heterogeneity. Eight high-quality trials (n = 478) were included. Exercise improved the serum concentrations of IL6 [weighted mean difference (WMD) = -0.55 pg/mL; 95% confidence interval (CI), -1.02 to -0.09], TNF? (WMD = -0.64 pg/mL; 95%CI, -1.21 to -0.06), IL8(MD= -0.49 pg/mL; 95% CI, -0.89 to -0.09), and IL2 (WMD = 1.03 pg/mL; 95% CI, 0.40 to 1.67). No significant differences were found in the serum concentrations of C-reactive protein (WMD = -0.15; 95% CI, -0.56 to 0.25) or IL10 (WMD = 0.41; 95% CI, -0.18 to 1.02). Exercise training positively modulates chronic low-grade inflammation in women with breast cancer, which may impact upon carcinogenic mechanisms and the tumor microenvironment. These findings align with the other positive effects of exercise for breast cancer survivors, reinforcing the appropriateness of exercise prescription in this population. © 2016 American Association for Cancer Research.
publishDate 2016
dc.date.created.spa.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:03:51Z
dc.date.available.none.fl_str_mv 2020-05-26T00:03:51Z
dc.type.eng.fl_str_mv article
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dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1158/1055-9965.EPI-15-1061
dc.identifier.issn.none.fl_str_mv 10559965
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/23634
url https://doi.org/10.1158/1055-9965.EPI-15-1061
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dc.relation.citationIssue.none.fl_str_mv No. 7
dc.relation.citationStartPage.none.fl_str_mv 1009
dc.relation.citationTitle.none.fl_str_mv Cancer Epidemiology Biomarkers and Prevention
dc.relation.citationVolume.none.fl_str_mv Vol. 25
dc.relation.ispartof.spa.fl_str_mv Cancer Epidemiology Biomarkers and Prevention, ISSN:10559965, Vol.25, No.7 (2016); pp. 1009-1017
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dc.publisher.spa.fl_str_mv American Association for Cancer Research Inc.
institution Universidad del Rosario
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