Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis

The purpose of this study was to examine the combined association of sitting time and physical activity with cognitive function and to determine whether moderate-to-vigorous physical activity (MVPA) is a mediator of the association between sitting time and cognitive function in a nationally represen...

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Autores:
Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/24034
Acceso en línea:
https://doi.org/10.1016/j.exger.2018.03.002
https://repository.urosario.edu.co/handle/10336/24034
Palabra clave:
Aged
Alcohol consumption
Article
Attention
Body mass
Cognitive defect
Composite international diagnostic interview
Controlled study
Depression
Depression assessment
Disease association
Dsm-iv
Female
Human
Language
Major clinical study
Male
Memory
Metabolic equivalent
Mini mental state examination
Orientation
Physical activity
Prevalence
Priority journal
Sitting
Tobacco use
Aging
Chile
Cognition
Cognitive defect
Cross-sectional study
Exercise
Health survey
Psychological rating scale
Psychology
Statistical model
Very elderly
Aged
Aged, 80 and over
Aging
Chile
Cognition
Cognitive dysfunction
Cross-sectional studies
Exercise
Female
Health surveys
Humans
Logistic models
Male
Psychiatric status rating scales
Sedentary behavior
Aging
Cognitive impairment
Physical inactivity
Sedentary behavior
Rights
License
Abierto (Texto Completo)
id EDOCUR2_b92f03de5723169e0416df1da0de0d8f
oai_identifier_str oai:repository.urosario.edu.co:10336/24034
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling d1123b4d-11e1-4338-99f1-023fe485bb27-194518183-1b5eaae93-2e4f-4f39-a9b5-b936665586d9-1c98a93bb-c97e-4c84-a571-45dd83fe3b30-175b6b2fa-230d-4c46-b327-97ca28a5215a-12020-05-26T00:07:49Z2020-05-26T00:07:49Z2018The purpose of this study was to examine the combined association of sitting time and physical activity with cognitive function and to determine whether moderate-to-vigorous physical activity (MVPA) is a mediator of the association between sitting time and cognitive function in a nationally representative sample of older adults from Chile. Data from 989 older adults (?65 years old, 61.3% female) from the 2009–2010 Chilean Health Survey were analyzed. Physical activity and sitting time were measured using the Global Physical Activity questionnaire. Cognitive function was assessed using the modified Mini-Mental State levels Examination. Physical activity levels were categorized as “inactive” ( less than 600 metabolic equivalent value minutes per week) or “active” (?600 metabolic equivalent value minutes per week). Sitting time was categorized as “sedentary”, defined as ?4 h of reported sitting time per day, or “non-sedentary”, defined as less than 4 h. We created the following groups (i) non-sedentary/active; (ii) non-sedentary/inactive; (iii) sedentary/active; and (iv) sedentary/inactive. Hayes's PROCESS macro was used for the simple mediation analysis. Compared with the reference group (individuals classified as non-sedentary/active), older adults who were classified as sedentary/active had elevated odds of cognitive impairment (OR = 1.90, [95% CI, 1.84 to 3.85]). However, the odds ratio for cognitive impairment was substantially increased in those classified as sedentary/inactive (OR = 4.85 [95% CI, 2.54 to 6.24]) compared with the reference group. MVPA was found to mediate the relationship between sitting time and cognitive function (Indirect Effect = ?0.070 [95% CI, ?0.012 to ?0.004]). Conclusion: The present findings suggest that, whether overall physical activity is high or low, spending large amounts of time sitting is associated with elevated odds of cognitive impairment and that MVPA slightly weakens the relationship between sitting time and cognitive function. © 2018 Elsevier Inc.application/pdfhttps://doi.org/10.1016/j.exger.2018.03.0025315565https://repository.urosario.edu.co/handle/10336/24034engElsevier Inc.177173Experimental GerontologyVol. 106Experimental Gerontology, ISSN:5315565, Vol.106,(2018); pp. 173-177https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043999950&doi=10.1016%2fj.exger.2018.03.002&partnerID=40&md5=df7e049e9c2ba61b299077463fddebd3Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAgedAlcohol consumptionArticleAttentionBody massCognitive defectComposite international diagnostic interviewControlled studyDepressionDepression assessmentDisease associationDsm-ivFemaleHumanLanguageMajor clinical studyMaleMemoryMetabolic equivalentMini mental state examinationOrientationPhysical activityPrevalencePriority journalSittingTobacco useAgingChileCognitionCognitive defectCross-sectional studyExerciseHealth surveyPsychological rating scalePsychologyStatistical modelVery elderlyAgedAged, 80 and overAgingChileCognitionCognitive dysfunctionCross-sectional studiesExerciseFemaleHealth surveysHumansLogistic modelsMalePsychiatric status rating scalesSedentary behaviorAgingCognitive impairmentPhysical inactivitySedentary behaviorCan physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysisarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501García-Hermoso, AntonioRamírez-Vélez, RobinsonCelis-Morales, Carlos A.Olloquequi, JordiIzquierdo, Mikel10336/24034oai:repository.urosario.edu.co:10336/240342022-05-02 07:37:21.355628https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
title Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
spellingShingle Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
Aged
Alcohol consumption
Article
Attention
Body mass
Cognitive defect
Composite international diagnostic interview
Controlled study
Depression
Depression assessment
Disease association
Dsm-iv
Female
Human
Language
Major clinical study
Male
Memory
Metabolic equivalent
Mini mental state examination
Orientation
Physical activity
Prevalence
Priority journal
Sitting
Tobacco use
Aging
Chile
Cognition
Cognitive defect
Cross-sectional study
Exercise
Health survey
Psychological rating scale
Psychology
Statistical model
Very elderly
Aged
Aged, 80 and over
Aging
Chile
Cognition
Cognitive dysfunction
Cross-sectional studies
Exercise
Female
Health surveys
Humans
Logistic models
Male
Psychiatric status rating scales
Sedentary behavior
Aging
Cognitive impairment
Physical inactivity
Sedentary behavior
title_short Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
title_full Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
title_fullStr Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
title_full_unstemmed Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
title_sort Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis
dc.subject.keyword.spa.fl_str_mv Aged
Alcohol consumption
Article
Attention
Body mass
Cognitive defect
Composite international diagnostic interview
Controlled study
Depression
Depression assessment
Disease association
Dsm-iv
Female
Human
Language
Major clinical study
Male
Memory
Metabolic equivalent
Mini mental state examination
Orientation
Physical activity
Prevalence
Priority journal
Sitting
Tobacco use
Aging
Chile
Cognition
Cognitive defect
Cross-sectional study
Exercise
Health survey
Psychological rating scale
Psychology
Statistical model
Very elderly
Aged
Aged, 80 and over
Aging
Chile
Cognition
Cognitive dysfunction
Cross-sectional studies
Exercise
Female
Health surveys
Humans
Logistic models
Male
Psychiatric status rating scales
Sedentary behavior
Aging
Cognitive impairment
Physical inactivity
Sedentary behavior
topic Aged
Alcohol consumption
Article
Attention
Body mass
Cognitive defect
Composite international diagnostic interview
Controlled study
Depression
Depression assessment
Disease association
Dsm-iv
Female
Human
Language
Major clinical study
Male
Memory
Metabolic equivalent
Mini mental state examination
Orientation
Physical activity
Prevalence
Priority journal
Sitting
Tobacco use
Aging
Chile
Cognition
Cognitive defect
Cross-sectional study
Exercise
Health survey
Psychological rating scale
Psychology
Statistical model
Very elderly
Aged
Aged, 80 and over
Aging
Chile
Cognition
Cognitive dysfunction
Cross-sectional studies
Exercise
Female
Health surveys
Humans
Logistic models
Male
Psychiatric status rating scales
Sedentary behavior
Aging
Cognitive impairment
Physical inactivity
Sedentary behavior
description The purpose of this study was to examine the combined association of sitting time and physical activity with cognitive function and to determine whether moderate-to-vigorous physical activity (MVPA) is a mediator of the association between sitting time and cognitive function in a nationally representative sample of older adults from Chile. Data from 989 older adults (?65 years old, 61.3% female) from the 2009–2010 Chilean Health Survey were analyzed. Physical activity and sitting time were measured using the Global Physical Activity questionnaire. Cognitive function was assessed using the modified Mini-Mental State levels Examination. Physical activity levels were categorized as “inactive” ( less than 600 metabolic equivalent value minutes per week) or “active” (?600 metabolic equivalent value minutes per week). Sitting time was categorized as “sedentary”, defined as ?4 h of reported sitting time per day, or “non-sedentary”, defined as less than 4 h. We created the following groups (i) non-sedentary/active; (ii) non-sedentary/inactive; (iii) sedentary/active; and (iv) sedentary/inactive. Hayes's PROCESS macro was used for the simple mediation analysis. Compared with the reference group (individuals classified as non-sedentary/active), older adults who were classified as sedentary/active had elevated odds of cognitive impairment (OR = 1.90, [95% CI, 1.84 to 3.85]). However, the odds ratio for cognitive impairment was substantially increased in those classified as sedentary/inactive (OR = 4.85 [95% CI, 2.54 to 6.24]) compared with the reference group. MVPA was found to mediate the relationship between sitting time and cognitive function (Indirect Effect = ?0.070 [95% CI, ?0.012 to ?0.004]). Conclusion: The present findings suggest that, whether overall physical activity is high or low, spending large amounts of time sitting is associated with elevated odds of cognitive impairment and that MVPA slightly weakens the relationship between sitting time and cognitive function. © 2018 Elsevier Inc.
publishDate 2018
dc.date.created.spa.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:07:49Z
dc.date.available.none.fl_str_mv 2020-05-26T00:07:49Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.exger.2018.03.002
dc.identifier.issn.none.fl_str_mv 5315565
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/24034
url https://doi.org/10.1016/j.exger.2018.03.002
https://repository.urosario.edu.co/handle/10336/24034
identifier_str_mv 5315565
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 177
dc.relation.citationStartPage.none.fl_str_mv 173
dc.relation.citationTitle.none.fl_str_mv Experimental Gerontology
dc.relation.citationVolume.none.fl_str_mv Vol. 106
dc.relation.ispartof.spa.fl_str_mv Experimental Gerontology, ISSN:5315565, Vol.106,(2018); pp. 173-177
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043999950&doi=10.1016%2fj.exger.2018.03.002&partnerID=40&md5=df7e049e9c2ba61b299077463fddebd3
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Elsevier Inc.
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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