Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates

Background: Currently, reliable reference values of regional cerebral oxygen saturation (rScO2) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO2) and blood pressure in ne...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2015
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/26855
Acceso en línea:
https://doi.org/10.1038/pr.2015.186
https://repository.urosario.edu.co/handle/10336/26855
Palabra clave:
Neonatolog
Preterm birth
Rights
License
Abierto (Texto Completo)
id EDOCUR2_b397ca309f745bbc561a5cdc0a0f84e0
oai_identifier_str oai:repository.urosario.edu.co:10336/26855
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling fa5269e9-e8e3-4541-8566-008e9ef870ca-1ebe2b702-8133-426b-8cec-8ce71ecde941-157d928dd-e973-4229-aa4c-c97fa2197792-1373c77e3-5093-43fd-831b-0db88cefa50d-155320cda-97a5-498e-9555-cec06026ceda-1d195c107-8f47-4fc0-a1d5-2001745cef86-11d162d95-7736-4068-ab14-cba2d36b67a2-196a23ae0-f7bb-46ab-afe4-4ff142ad6509-1141395126002020-08-19T14:40:23Z2020-08-19T14:40:23Z2015-09-21Background: Currently, reliable reference values of regional cerebral oxygen saturation (rScO2) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO2) and blood pressure in neonatal intensive care. The aim of this study was to provide reference values for rScO2 and cerebral fractional tissue oxygen extraction (cFTOE; (SaO2 ? rScO2)/SaO2) for small adult and neonatal NIRS sensors. Methods: In this study, 999 infants born preterm (GA <32?wk) were monitored with NIRS during the first 72?h of life. Mixed modeling was used to generate reference curves grouped per 2?wk of GA. In addition, the influence of a hemodynamically significant patent ductus arteriosus, gender, and birth weight were explored. Results: Average rScO2 was ~65% at admission, increased with GA (1% per week) and followed a parabolic curve in relation to postnatal age with a peak at ~36?h. The cFTOE showed similar but inverse effects. On average, the neonatal sensor measured 10% higher than the adult sensor. Conclusion: rScO2 and cFTOE reference curves are provided for the first 72?h of life in preterm infants, which might support the broader implementation of NIRS in neonatal intensive care.application/pdfhttps://doi.org/10.1038/pr.2015.186ISSN: 0031-3998EISSN: 1530-0447https://repository.urosario.edu.co/handle/10336/26855engInternational Pediatric Research FoundationSpringer Nature64No. 155Pediatric ResearchVol. 79Pediatric Research, ISSN: 0031-3998;EISSN: 1530-0447, Vol.79, No.1(January 2016); pp. 55–64https://www.nature.com/articles/pr2015186.pdfAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Pediatric Researchinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURNeonatologPreterm birthReference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonatesValores de referencia de la saturación de oxígeno cerebral regional durante los primeros 3 días de vida en neonatos prematurosarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Alderliesten, ThomasDix, LauraBaerts, Wimvan Huffel, SabineNaulaers, GunnarGroenendaal, Florisvan Bel, FrankLemmers, PetraCaicedo Dorado, Alexander10336/26855oai:repository.urosario.edu.co:10336/268552022-05-02 07:37:13.409661https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
dc.title.TranslatedTitle.spa.fl_str_mv Valores de referencia de la saturación de oxígeno cerebral regional durante los primeros 3 días de vida en neonatos prematuros
title Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
spellingShingle Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
Neonatolog
Preterm birth
title_short Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
title_full Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
title_fullStr Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
title_full_unstemmed Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
title_sort Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates
dc.subject.keyword.spa.fl_str_mv Neonatolog
Preterm birth
topic Neonatolog
Preterm birth
description Background: Currently, reliable reference values of regional cerebral oxygen saturation (rScO2) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO2) and blood pressure in neonatal intensive care. The aim of this study was to provide reference values for rScO2 and cerebral fractional tissue oxygen extraction (cFTOE; (SaO2 ? rScO2)/SaO2) for small adult and neonatal NIRS sensors. Methods: In this study, 999 infants born preterm (GA <32?wk) were monitored with NIRS during the first 72?h of life. Mixed modeling was used to generate reference curves grouped per 2?wk of GA. In addition, the influence of a hemodynamically significant patent ductus arteriosus, gender, and birth weight were explored. Results: Average rScO2 was ~65% at admission, increased with GA (1% per week) and followed a parabolic curve in relation to postnatal age with a peak at ~36?h. The cFTOE showed similar but inverse effects. On average, the neonatal sensor measured 10% higher than the adult sensor. Conclusion: rScO2 and cFTOE reference curves are provided for the first 72?h of life in preterm infants, which might support the broader implementation of NIRS in neonatal intensive care.
publishDate 2015
dc.date.created.spa.fl_str_mv 2015-09-21
dc.date.accessioned.none.fl_str_mv 2020-08-19T14:40:23Z
dc.date.available.none.fl_str_mv 2020-08-19T14:40:23Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1038/pr.2015.186
dc.identifier.issn.none.fl_str_mv ISSN: 0031-3998
EISSN: 1530-0447
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/26855
url https://doi.org/10.1038/pr.2015.186
https://repository.urosario.edu.co/handle/10336/26855
identifier_str_mv ISSN: 0031-3998
EISSN: 1530-0447
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 64
dc.relation.citationIssue.none.fl_str_mv No. 1
dc.relation.citationStartPage.none.fl_str_mv 55
dc.relation.citationTitle.none.fl_str_mv Pediatric Research
dc.relation.citationVolume.none.fl_str_mv Vol. 79
dc.relation.ispartof.spa.fl_str_mv Pediatric Research, ISSN: 0031-3998;EISSN: 1530-0447, Vol.79, No.1(January 2016); pp. 55–64
dc.relation.uri.spa.fl_str_mv https://www.nature.com/articles/pr2015186.pdf
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv International Pediatric Research Foundation
Springer Nature
dc.source.spa.fl_str_mv Pediatric Research
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
_version_ 1814167463275790336