Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America

Introduction: Hypospadias is a congenital abnormality of the penis, in which there is incomplete development of the distal urethra. There are numerous reports showing an increase of prevalence of hypospadias. Association of craniofacial malformations in patients diagnosed with hypospadias is rare. T...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2016
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/21394
Acceso en línea:
https://doi.org/10.1590/S1677-5538.IBJU.2015.0568
https://repository.urosario.edu.co/handle/10336/21394
Palabra clave:
clinical trial
Craniofacial Abnormalities
health survey
hypospadias
male
multicenter study
newborn
South America
Craniofacial Abnormalities
Hypospadias
Male
Population Surveillance
Prevalence
South America
Hipospadias
Craneofacial anormalidades
Sudamerica
Grupos de población
Enfermedades
Hypospadias
Craniofacial abnormalities
South America
human
Population groups
prevalence
Humans
Newborn
Infant
Hipospadias
Anomalías congénitas
Rights
License
Abierto (Texto Completo)
id EDOCUR2_b25d161d6c7138309f497033450aee3a
oai_identifier_str oai:repository.urosario.edu.co:10336/21394
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling b0ac9b64-c745-4900-904f-af2a8c2dce0f60012ef79e6-e20b-4086-bfab-af0bbb4d758f60085df9ec7-d0b3-4a65-946b-d1f2bfa0b5196002020-04-02T02:52:08Z2020-04-02T02:52:08Z2016-082016Introduction: Hypospadias is a congenital abnormality of the penis, in which there is incomplete development of the distal urethra. There are numerous reports showing an increase of prevalence of hypospadias. Association of craniofacial malformations in patients diagnosed with hypospadias is rare. The aim of this study is to describe the association between hypospadias and craniofacial congenital anomalies. Materials and Methods: A retrospective review of the Latin-American collaborative study of congenital malformations (ECLAMC) data was performed between January 1982 and December 2011. We included children diagnosed with associated hypospadias and among them we selected those that were associated with any craniofacial congenital anomaly. Results: Global prevalence was 11.3 per 10.000 newborns. In this population a total of 809 patients with 1117 associated anomalies were identified. On average there were 1.7 anomalies per patient. Facial anomalies were present in 13.2%. The most commonly major facial anomaly associated to hypospadias was cleft lip/palate with 52 cases. We identified that 18% have an association with other anomalies, and found an association between craniofacial anomalies and hypospadias in 0.59 cases/10.000 newborns. Discussion: Hypospadias is the most common congenital anomaly affecting the genitals. Its association with other anomalies is rare. It has been reported that other malformations occur in 29.3% of the cases with hypospadias. The more proximal the meatus, the higher the risk for having another associated anomaly. Conclusion: Associated hypospadias are rare, and it is important to identify the concurrent occurrence of craniofacial anomalies to better treat patients that might need a multidisciplinary approach.application/pdfhttps://doi.org/10.1590/S1677-5538.IBJU.2015.05681677-5538https://repository.urosario.edu.co/handle/10336/21394eng797No. 4793International Braz J UrolVol. 42International Braz J Urol, ISSN: 1677-5538 Vol. 42, No. 4 (2016) pp. 793-797http://www.scielo.br/pdf/ibju/v42n4/1677-5538-ibju-42-04-0793.pdfAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURclinical trialCraniofacial Abnormalitieshealth surveyhypospadiasmalemulticenter studynewbornSouth AmericaCraniofacial AbnormalitiesHypospadiasMalePopulation SurveillancePrevalenceSouth AmericaHipospadiasCraneofacial anormalidadesSudamericaGrupos de poblaciónEnfermedades616600HypospadiasCraniofacial abnormalitiesSouth AmericahumanPopulation groupsprevalenceHumansNewbornInfantHipospadiasAnomalías congénitasCraniofacial anomalies associated with hypospadias. Description of a hospital based population in South AmericaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Fernandez, NicolasEscobar, RebecaZarante, IgnacioFernandez, NicolasEscobar, RebecaZarante, IgnacioORIGINALCraniofacial_anomalies_associated_with_hypospadias.pdfapplication/pdf487445https://repository.urosario.edu.co/bitstreams/00deee80-a2c1-4a6b-9e04-81089c197c53/download597314e9f5e437527be3740a33f124b2MD51TEXTCraniofacial_anomalies_associated_with_hypospadias.pdf.txtCraniofacial_anomalies_associated_with_hypospadias.pdf.txtExtracted texttext/plain17606https://repository.urosario.edu.co/bitstreams/567609c2-c386-47bd-8fd1-ad98018901cb/download2bb929e08d2d2764b6a1007189ad4e00MD52THUMBNAILCraniofacial_anomalies_associated_with_hypospadias.pdf.jpgCraniofacial_anomalies_associated_with_hypospadias.pdf.jpgGenerated Thumbnailimage/jpeg4405https://repository.urosario.edu.co/bitstreams/45aaa3b0-f96c-40a2-a0f7-a8b4c47c546b/download8173101b58dda8821ff226091ba15022MD5310336/21394oai:repository.urosario.edu.co:10336/213942020-05-13 14:47:45.641https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
title Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
spellingShingle Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
clinical trial
Craniofacial Abnormalities
health survey
hypospadias
male
multicenter study
newborn
South America
Craniofacial Abnormalities
Hypospadias
Male
Population Surveillance
Prevalence
South America
Hipospadias
Craneofacial anormalidades
Sudamerica
Grupos de población
Enfermedades
Hypospadias
Craniofacial abnormalities
South America
human
Population groups
prevalence
Humans
Newborn
Infant
Hipospadias
Anomalías congénitas
title_short Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
title_full Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
title_fullStr Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
title_full_unstemmed Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
title_sort Craniofacial anomalies associated with hypospadias. Description of a hospital based population in South America
dc.subject.spa.fl_str_mv clinical trial
Craniofacial Abnormalities
health survey
hypospadias
male
multicenter study
newborn
South America
Craniofacial Abnormalities
Hypospadias
Male
Population Surveillance
Prevalence
South America
Hipospadias
Craneofacial anormalidades
Sudamerica
Grupos de población
topic clinical trial
Craniofacial Abnormalities
health survey
hypospadias
male
multicenter study
newborn
South America
Craniofacial Abnormalities
Hypospadias
Male
Population Surveillance
Prevalence
South America
Hipospadias
Craneofacial anormalidades
Sudamerica
Grupos de población
Enfermedades
Hypospadias
Craniofacial abnormalities
South America
human
Population groups
prevalence
Humans
Newborn
Infant
Hipospadias
Anomalías congénitas
dc.subject.ddc.spa.fl_str_mv Enfermedades
dc.subject.keyword.spa.fl_str_mv Hypospadias
Craniofacial abnormalities
South America
human
Population groups
prevalence
Humans
dc.subject.keyword.eng.fl_str_mv Newborn
Infant
dc.subject.lemb.spa.fl_str_mv Hipospadias
Anomalías congénitas
description Introduction: Hypospadias is a congenital abnormality of the penis, in which there is incomplete development of the distal urethra. There are numerous reports showing an increase of prevalence of hypospadias. Association of craniofacial malformations in patients diagnosed with hypospadias is rare. The aim of this study is to describe the association between hypospadias and craniofacial congenital anomalies. Materials and Methods: A retrospective review of the Latin-American collaborative study of congenital malformations (ECLAMC) data was performed between January 1982 and December 2011. We included children diagnosed with associated hypospadias and among them we selected those that were associated with any craniofacial congenital anomaly. Results: Global prevalence was 11.3 per 10.000 newborns. In this population a total of 809 patients with 1117 associated anomalies were identified. On average there were 1.7 anomalies per patient. Facial anomalies were present in 13.2%. The most commonly major facial anomaly associated to hypospadias was cleft lip/palate with 52 cases. We identified that 18% have an association with other anomalies, and found an association between craniofacial anomalies and hypospadias in 0.59 cases/10.000 newborns. Discussion: Hypospadias is the most common congenital anomaly affecting the genitals. Its association with other anomalies is rare. It has been reported that other malformations occur in 29.3% of the cases with hypospadias. The more proximal the meatus, the higher the risk for having another associated anomaly. Conclusion: Associated hypospadias are rare, and it is important to identify the concurrent occurrence of craniofacial anomalies to better treat patients that might need a multidisciplinary approach.
publishDate 2016
dc.date.created.none.fl_str_mv 2016-08
dc.date.issued.none.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2020-04-02T02:52:08Z
dc.date.available.none.fl_str_mv 2020-04-02T02:52:08Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1590/S1677-5538.IBJU.2015.0568
dc.identifier.issn.none.fl_str_mv 1677-5538
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/21394
url https://doi.org/10.1590/S1677-5538.IBJU.2015.0568
https://repository.urosario.edu.co/handle/10336/21394
identifier_str_mv 1677-5538
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 797
dc.relation.citationIssue.none.fl_str_mv No. 4
dc.relation.citationStartPage.none.fl_str_mv 793
dc.relation.citationTitle.none.fl_str_mv International Braz J Urol
dc.relation.citationVolume.none.fl_str_mv Vol. 42
dc.relation.ispartof.spa.fl_str_mv International Braz J Urol, ISSN: 1677-5538 Vol. 42, No. 4 (2016) pp. 793-797
dc.relation.uri.spa.fl_str_mv http://www.scielo.br/pdf/ibju/v42n4/1677-5538-ibju-42-04-0793.pdf
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
bitstream.url.fl_str_mv https://repository.urosario.edu.co/bitstreams/00deee80-a2c1-4a6b-9e04-81089c197c53/download
https://repository.urosario.edu.co/bitstreams/567609c2-c386-47bd-8fd1-ad98018901cb/download
https://repository.urosario.edu.co/bitstreams/45aaa3b0-f96c-40a2-a0f7-a8b4c47c546b/download
bitstream.checksum.fl_str_mv 597314e9f5e437527be3740a33f124b2
2bb929e08d2d2764b6a1007189ad4e00
8173101b58dda8821ff226091ba15022
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
_version_ 1814167517036281856