Functional magnetic resonance in medicine students with and without partial sleep restriction

OBJECTIVE To describe the effects of partial sleep restriction (PSR) in the brain regions involved in cognitive inhibition processes, motor function and phonological fluency using functional Magnetic Resonance Imaging (fMRI). METHOD A sample of 12 graduate medicine students were subject to a follow-up of the number of hours of habitual sleep and underwent fMRI studies evaluating 4 paradigms before and after the PSR : Stroop (in standard and modified versions), right hand movement and verbal fluency. The PSR was equivalent to one night-shift, with at least 45 % sleep restriction with respect to the habitual sleep pattern during the previous week. The d2 attention test was done before and after the PSR to evaluate attention. RESULTS The d2 attention test did not show any significant differences between the habitual sleep condition and the PSR. Significant differences were found in BOLD activity for the motor function (P<0.05). Changes in BOLD activity were not observed for the Stroop nor verbal fluency paradigms.

• Fecha de publicación: 2013
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/26490
• Acceso en línea: https://doi.org/10.1007/s00234-013-1236-8; https://repository.urosario.edu.co/handle/10336/26490
• Palabra clave: Animals; Humans; Nervous System; Nervous System Diseases; Neuroradiography; Radiology; Interventional
• License: http://purl.org/coar/access_right/c_16ec