The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity

Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family. Second, the phy...

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Tipo de recurso:
Fecha de publicación:
2007
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/24043
Acceso en línea:
https://doi.org/10.1586/1744666X.3.4.623
https://repository.urosario.edu.co/handle/10336/24043
Palabra clave:
Autoimmune disease
Autoimmune polyendocrinopathy
Autoimmune polyglandular syndrome type ii
Autoimmunity
Disease predisposition
Disease severity
Environmental factor
Familial disease
Family history
Gender
Human
Inheritance
Medline
Mosaicism
Nuclear family
Onset age
Pathophysiology
Phenotype
Review
Risk factor
Sex difference
X chromosome
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License
Abierto (Texto Completo)
id EDOCUR2_aecdbf96570564d8cee6404ae117bae7
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network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 19474778600a642d5e9-f948-4ddf-a7a1-278a7ea7115151cf37f6-25b0-4152-ae95-bb2b21ce5d7e52249701ef6fa7cf-59f5-4c86-bc53-d389160d7ddf2020-05-26T00:07:57Z2020-05-26T00:07:57Z2007Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family. Second, the physiopathologic evidence indicating that the pathologic mechanisms might be similar among ADs. Lost, the genetic evidence indicating that autoimmune phenotypes could represent pleiotropic outcomes of nonspecific disease genes. The two conditions that better illustrate the kaleidoscope of autoimmunity are multiple autoimmune syndromes and familial autoimmunity. The multiple autoimmune syndromes consist of the presence of three or more well-defined autoimmune conditions in a single patient. The familial autoimmunity is defined as the presence of diverse ADs on multiple members of a nuclear family. Herein, both the multiple autoimmune syndromes and familial autoimmunity are discussed and various epidemiological factors considered in the context of the common genetic background of autoimmunity. © 2007 Future Drugs Ltd.application/pdfhttps://doi.org/10.1586/1744666X.3.4.6231744666X17448409https://repository.urosario.edu.co/handle/10336/24043eng635No. 4623Expert Review of Clinical ImmunologyVol. 3Expert Review of Clinical Immunology, ISSN:1744666X, 17448409, Vol.3, No.4 (2007); pp. 623-635https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547104853&doi=10.1586%2f1744666X.3.4.623&partnerID=40&md5=64259d568c3ce9d43ebc6b9d250bef91Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAutoimmune diseaseAutoimmune polyendocrinopathyAutoimmune polyglandular syndrome type iiAutoimmunityDisease predispositionDisease severityEnvironmental factorFamilial diseaseFamily historyGenderHumanInheritanceMedlineMosaicismNuclear familyOnset agePathophysiologyPhenotypeReviewRisk factorSex differenceX chromosomeThe kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunityarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Anaya, Juan-ManuelCorena, RodrigoCastiblanco, JohnRojas-Villarraga, AdrianaShoenfeld, Yehuda10336/24043oai:repository.urosario.edu.co:10336/240432022-05-02 07:37:13.786946https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
title The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
spellingShingle The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
Autoimmune disease
Autoimmune polyendocrinopathy
Autoimmune polyglandular syndrome type ii
Autoimmunity
Disease predisposition
Disease severity
Environmental factor
Familial disease
Family history
Gender
Human
Inheritance
Medline
Mosaicism
Nuclear family
Onset age
Pathophysiology
Phenotype
Review
Risk factor
Sex difference
X chromosome
title_short The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
title_full The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
title_fullStr The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
title_full_unstemmed The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
title_sort The kaleidoscope of autoimmunity: Multiple autoimmune syndromes and familial autoimmunity
dc.subject.keyword.spa.fl_str_mv Autoimmune disease
Autoimmune polyendocrinopathy
Autoimmune polyglandular syndrome type ii
Autoimmunity
Disease predisposition
Disease severity
Environmental factor
Familial disease
Family history
Gender
Human
Inheritance
Medline
Mosaicism
Nuclear family
Onset age
Pathophysiology
Phenotype
Review
Risk factor
Sex difference
X chromosome
topic Autoimmune disease
Autoimmune polyendocrinopathy
Autoimmune polyglandular syndrome type ii
Autoimmunity
Disease predisposition
Disease severity
Environmental factor
Familial disease
Family history
Gender
Human
Inheritance
Medline
Mosaicism
Nuclear family
Onset age
Pathophysiology
Phenotype
Review
Risk factor
Sex difference
X chromosome
description Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family. Second, the physiopathologic evidence indicating that the pathologic mechanisms might be similar among ADs. Lost, the genetic evidence indicating that autoimmune phenotypes could represent pleiotropic outcomes of nonspecific disease genes. The two conditions that better illustrate the kaleidoscope of autoimmunity are multiple autoimmune syndromes and familial autoimmunity. The multiple autoimmune syndromes consist of the presence of three or more well-defined autoimmune conditions in a single patient. The familial autoimmunity is defined as the presence of diverse ADs on multiple members of a nuclear family. Herein, both the multiple autoimmune syndromes and familial autoimmunity are discussed and various epidemiological factors considered in the context of the common genetic background of autoimmunity. © 2007 Future Drugs Ltd.
publishDate 2007
dc.date.created.spa.fl_str_mv 2007
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:07:57Z
dc.date.available.none.fl_str_mv 2020-05-26T00:07:57Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1586/1744666X.3.4.623
dc.identifier.issn.none.fl_str_mv 1744666X
17448409
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/24043
url https://doi.org/10.1586/1744666X.3.4.623
https://repository.urosario.edu.co/handle/10336/24043
identifier_str_mv 1744666X
17448409
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 635
dc.relation.citationIssue.none.fl_str_mv No. 4
dc.relation.citationStartPage.none.fl_str_mv 623
dc.relation.citationTitle.none.fl_str_mv Expert Review of Clinical Immunology
dc.relation.citationVolume.none.fl_str_mv Vol. 3
dc.relation.ispartof.spa.fl_str_mv Expert Review of Clinical Immunology, ISSN:1744666X, 17448409, Vol.3, No.4 (2007); pp. 623-635
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547104853&doi=10.1586%2f1744666X.3.4.623&partnerID=40&md5=64259d568c3ce9d43ebc6b9d250bef91
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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