Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus

The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive P...

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Tipo de recurso:
Fecha de publicación:
2015
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/19014
Acceso en línea:
http://repository.urosario.edu.co/handle/10336/19014
Palabra clave:
Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
Enfermedades
Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
Malaria
Vacuna
Plasmodium
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
spellingShingle Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
Enfermedades
Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
Malaria
Vacuna
Plasmodium
title_short Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_full Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_fullStr Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_full_unstemmed Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
title_sort Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus
dc.subject.spa.fl_str_mv Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
topic Impips
Malaria Vaccine
Modified Peptides
Synthetic Peptides
Enfermedades
Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
Malaria
Vacuna
Plasmodium
dc.subject.ddc.spa.fl_str_mv Enfermedades
dc.subject.decs.spa.fl_str_mv Hla Dr1 Antigen
Malaria Vaccine
T Lymphocyte Receptor
Malaria Vaccine
Peptide
Protozoal Protein
Recombinant Vaccine
Alpha Helix
Amino Acid Sequence
Antibody Response
Antibody Titer
Aotus
Article
Beta Sheet
Conformational Transition
Erythrocyte
Genetic Trait
Genetic Variability
Human
Humoral Immunity
Hydrogen Bond
Immune Protection Inducing Protein Structure
Immune Response
Immunogenetics
Immunogenicity
Immunological Silence
Malaria Falciparum
Nonhuman
Plasmodium Falciparum
Priority Journal
Protein Conformation
Protein Structure
Chemistry
Immunology
Life Cycle Stage
Malaria, Falciparum
Metabolism
Physiology
Amino Acid Sequence
Humans
Life Cycle Stages
Malaria Vaccines
Malaria, Falciparum
Peptides
Plasmodium Falciparum
Protein Conformation
Protozoan Proteins
Vaccines, Synthetic
dc.subject.lemb.spa.fl_str_mv Malaria
Vacuna
Plasmodium
description The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of the epic poem Odyssey by Homer, and the elusive Plasmodium parasite has been made, to review our research group's main considerations when developing a rational methodology for designing second generation, modified peptide-based, minimal subunit, multi-antigen, multi-stage, chemically synthesised vaccines against Plasmodium falciparum malaria. © 2015 Elsevier Ltd.
publishDate 2015
dc.date.created.none.fl_str_mv 2015
dc.date.issued.none.fl_str_mv 2015
dc.date.accessioned.none.fl_str_mv 2019-02-05T19:54:55Z
dc.date.available.none.fl_str_mv 2019-02-05T19:54:55Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.issn.none.fl_str_mv ISSN 0264-410X
dc.identifier.uri.none.fl_str_mv http://repository.urosario.edu.co/handle/10336/19014
identifier_str_mv ISSN 0264-410X
url http://repository.urosario.edu.co/handle/10336/19014
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 7537
dc.relation.citationIssue.none.fl_str_mv No. 52
dc.relation.citationStartPage.none.fl_str_mv 7525
dc.relation.citationTitle.none.fl_str_mv Vaccine
dc.relation.citationVolume.none.fl_str_mv Vol. 33
dc.relation.ispartof.spa.fl_str_mv Vaccine, ISSN: 0264-410X, Vol. 33/No. 52 (2015) pp. 7525-7537
dc.relation.uri.spa.fl_str_mv https://ac.els-cdn.com/S0264410X15014127/1-s2.0-S0264410X15014127-main.pdf?_tid=1b8038aa-cb75-467a-90fb-feb6a865c820&acdnat=1540056249_a7a783bf39eb958684bb1f2d524741d8
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
dc.rights.cc.spa.fl_str_mv https://creativecommons.org/licenses/by/4.0/
rights_invalid_str_mv Abierto (Texto Completo)
https://creativecommons.org/licenses/by/4.0/
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
institution Universidad del Rosario
dc.source.bibliographicCitation.spa.fl_str_mv Homer, (1946) The Odyssey, , [Transl. by E.V. Rieu], Penguin Group, London, England
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
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