Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America

Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 report...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22829
Acceso en línea:
https://doi.org/10.1371/journal.pone.0223963
https://repository.urosario.edu.co/handle/10336/22829
Palabra clave:
Animal tissue
Ribosomal
Population
Molecular
DNA
Evolution
Genetics
Sequence analysis
Bayes theorem
Chagas disease
Cladistics
Controlled study
Genetic analysis
Genetic variability
Geographic distribution
Haplotype
Maximum likelihood method
Mitochondrion
Molecular phylogeny
Monophyly
Nonhuman
Panstrongylus
Panstrongylus chinai
Panstrongylus geniculatus
Panstrongylus howardi
Panstrongylus lignarius
Panstrongylus lutzi
Panstrongylus megistus
Panstrongylus rufotuberculatus
Panstrongylus tupynambai
Population dynamics
Population genetic structure
Ribosome
South america
Vector control
Animal
Cell nucleus
Classification
Dna sequence
Genetics
Molecular evolution
Population genetics
Ribosome dna
Animals
Cell nucleus
Mitochondria
Phylogeny
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
title Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
spellingShingle Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
Animal tissue
Ribosomal
Population
Molecular
DNA
Evolution
Genetics
Sequence analysis
Bayes theorem
Chagas disease
Cladistics
Controlled study
Genetic analysis
Genetic variability
Geographic distribution
Haplotype
Maximum likelihood method
Mitochondrion
Molecular phylogeny
Monophyly
Nonhuman
Panstrongylus
Panstrongylus chinai
Panstrongylus geniculatus
Panstrongylus howardi
Panstrongylus lignarius
Panstrongylus lutzi
Panstrongylus megistus
Panstrongylus rufotuberculatus
Panstrongylus tupynambai
Population dynamics
Population genetic structure
Ribosome
South america
Vector control
Animal
Cell nucleus
Classification
Dna sequence
Genetics
Molecular evolution
Population genetics
Ribosome dna
Animals
Cell nucleus
Mitochondria
Phylogeny
title_short Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
title_full Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
title_fullStr Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
title_full_unstemmed Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
title_sort Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
dc.subject.keyword.eng.fl_str_mv Animal tissue
Ribosomal
Population
Molecular
DNA
Evolution
Genetics
Sequence analysis
topic Animal tissue
Ribosomal
Population
Molecular
DNA
Evolution
Genetics
Sequence analysis
Bayes theorem
Chagas disease
Cladistics
Controlled study
Genetic analysis
Genetic variability
Geographic distribution
Haplotype
Maximum likelihood method
Mitochondrion
Molecular phylogeny
Monophyly
Nonhuman
Panstrongylus
Panstrongylus chinai
Panstrongylus geniculatus
Panstrongylus howardi
Panstrongylus lignarius
Panstrongylus lutzi
Panstrongylus megistus
Panstrongylus rufotuberculatus
Panstrongylus tupynambai
Population dynamics
Population genetic structure
Ribosome
South america
Vector control
Animal
Cell nucleus
Classification
Dna sequence
Genetics
Molecular evolution
Population genetics
Ribosome dna
Animals
Cell nucleus
Mitochondria
Phylogeny
dc.subject.keyword.spa.fl_str_mv Bayes theorem
Chagas disease
Cladistics
Controlled study
Genetic analysis
Genetic variability
Geographic distribution
Haplotype
Maximum likelihood method
Mitochondrion
Molecular phylogeny
Monophyly
Nonhuman
Panstrongylus
Panstrongylus chinai
Panstrongylus geniculatus
Panstrongylus howardi
Panstrongylus lignarius
Panstrongylus lutzi
Panstrongylus megistus
Panstrongylus rufotuberculatus
Panstrongylus tupynambai
Population dynamics
Population genetic structure
Ribosome
South america
Vector control
Animal
Cell nucleus
Classification
Dna sequence
Genetics
Molecular evolution
Population genetics
Ribosome dna
Animals
Cell nucleus
Mitochondria
Phylogeny
description Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 reported species but there is limited information about its intraspecific genetic variation and patterns of diversification. Here, we begin to fill this gap by studying populations of P. geniculatus from Colombia and Venezuela and including other epidemiologically important species from the region. We examined the pattern of diversification of P. geniculatus in Colombia using mitochondrial and nuclear ribosomal data. Genetic diversity and differentiation were calculated within and among populations of P. geniculatus. Moreover, we constructed maximum likelihood and Bayesian inference phylogenies and haplotype networks using P. geniculatus and other species from the genus (P. megistus, P. lignarius, P. lutzi, P. tupynambai, P. chinai, P. rufotuberculatus and P. howardi). Using a coalescence framework, we also dated the P. geniculatus lineages. The total evidence tree showed that P. geniculatus is a monophyletic species, with four clades that are concordant with its geographic distribution and are partly explained by the Andes orogeny. However, other factors, including anthropogenic and eco-epidemiological effects must be investigated to explain the existence of recent geographic P. geniculatus lineages. The epidemiological dynamics in structured vector populations, such as those found here, warrant further investigation. Extending our knowledge of P. geniculatus is necessary for the accurate development of effective strategies for the control of Chagas disease vectors. © 2019 Caicedo-Garzón et al.
publishDate 2019
dc.date.created.spa.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2020-05-25T23:58:15Z
dc.date.available.none.fl_str_mv 2020-05-25T23:58:15Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1371/journal.pone.0223963
dc.identifier.issn.none.fl_str_mv 19326203
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/22829
url https://doi.org/10.1371/journal.pone.0223963
https://repository.urosario.edu.co/handle/10336/22829
identifier_str_mv 19326203
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationIssue.none.fl_str_mv No. 10
dc.relation.citationTitle.none.fl_str_mv PLoS ONE
dc.relation.citationVolume.none.fl_str_mv Vol. 14
dc.relation.ispartof.spa.fl_str_mv PLoS ONE, ISSN:19326203, Vol.14, No.10 (2019)
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spelling 578e3d3c-f2f9-46c9-b26d-a86520d46983e5615101-17e0-4e13-a841-2721ea1bd5d052085795600692a650e-7580-460c-b76f-5faadab043e7171c89ac-b54e-4c3a-aab8-479bb2ea1fa792053314-5dfc-43b3-9f93-8bb75aac525780f15593-2cd2-4c43-b949-8694a201fb2e46828995-5913-4526-ab77-9ada33b1c5c772b434cb-fa1f-42d7-a27a-5336c651f710983bcf40-821b-4d28-b42d-d80c123ee306236c768d-b09f-449f-85d3-cc4b09cb9f5c351992566007987375760010117161186002020-05-25T23:58:15Z2020-05-25T23:58:15Z2019Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 reported species but there is limited information about its intraspecific genetic variation and patterns of diversification. Here, we begin to fill this gap by studying populations of P. geniculatus from Colombia and Venezuela and including other epidemiologically important species from the region. We examined the pattern of diversification of P. geniculatus in Colombia using mitochondrial and nuclear ribosomal data. Genetic diversity and differentiation were calculated within and among populations of P. geniculatus. Moreover, we constructed maximum likelihood and Bayesian inference phylogenies and haplotype networks using P. geniculatus and other species from the genus (P. megistus, P. lignarius, P. lutzi, P. tupynambai, P. chinai, P. rufotuberculatus and P. howardi). Using a coalescence framework, we also dated the P. geniculatus lineages. The total evidence tree showed that P. geniculatus is a monophyletic species, with four clades that are concordant with its geographic distribution and are partly explained by the Andes orogeny. However, other factors, including anthropogenic and eco-epidemiological effects must be investigated to explain the existence of recent geographic P. geniculatus lineages. The epidemiological dynamics in structured vector populations, such as those found here, warrant further investigation. Extending our knowledge of P. geniculatus is necessary for the accurate development of effective strategies for the control of Chagas disease vectors. © 2019 Caicedo-Garzón et al.application/pdfhttps://doi.org/10.1371/journal.pone.022396319326203https://repository.urosario.edu.co/handle/10336/22829engPublic Library of ScienceNo. 10PLoS ONEVol. 14PLoS ONE, ISSN:19326203, Vol.14, No.10 (2019)https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073594797&doi=10.1371%2fjournal.pone.0223963&partnerID=40&md5=62acc99a547a53be2ca5f47192c4214dAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAnimal tissueRibosomalPopulationMolecularDNAEvolutionGeneticsSequence analysisBayes theoremChagas diseaseCladisticsControlled studyGenetic analysisGenetic variabilityGeographic distributionHaplotypeMaximum likelihood methodMitochondrionMolecular phylogenyMonophylyNonhumanPanstrongylusPanstrongylus chinaiPanstrongylus geniculatusPanstrongylus howardiPanstrongylus lignariusPanstrongylus lutziPanstrongylus megistusPanstrongylus rufotuberculatusPanstrongylus tupynambaiPopulation dynamicsPopulation genetic structureRibosomeSouth americaVector controlAnimalCell nucleusClassificationDna sequenceGeneticsMolecular evolutionPopulation geneticsRibosome dnaAnimalsCell nucleusMitochondriaPhylogenyGenetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South AmericaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Caicedo-Garzón, ValentinaSalgado-Roa, Fabian C.Galindo Hernández, CarolinaArias-Giraldo, Luisa MaríaGarcía, LinethVallejo, GustavoCantillo, OmarTovar, Catalinada Rosa, Joao AristeuCarrasco, Hernán J.Segovia, MaikellSanchez-Herrera, MelissaSalazar, CamiloRamírez, Juan DavidORIGINALjournal-pone-0223963.pdfapplication/pdf2565250https://repository.urosario.edu.co/bitstreams/9d153ea6-216e-4279-a90e-72abf83230a0/download9c768d18d6abf40660565846a6b286a6MD51TEXTjournal-pone-0223963.pdf.txtjournal-pone-0223963.pdf.txtExtracted texttext/plain58537https://repository.urosario.edu.co/bitstreams/f923c6d3-6056-4a19-a95a-f15142d364ec/download7a0076503c235f4586fd5c22946c3e28MD52THUMBNAILjournal-pone-0223963.pdf.jpgjournal-pone-0223963.pdf.jpgGenerated Thumbnailimage/jpeg4424https://repository.urosario.edu.co/bitstreams/0a918f16-97f0-4fae-b811-00451b35971c/download9c158e5404af8000ad0eb2b14e1ab4baMD5310336/22829oai:repository.urosario.edu.co:10336/228292022-08-29 09:10:03.214https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co