Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 report...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2019
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/22829
- Acceso en línea:
- https://doi.org/10.1371/journal.pone.0223963
https://repository.urosario.edu.co/handle/10336/22829
- Palabra clave:
- Animal tissue
Ribosomal
Population
Molecular
DNA
Evolution
Genetics
Sequence analysis
Bayes theorem
Chagas disease
Cladistics
Controlled study
Genetic analysis
Genetic variability
Geographic distribution
Haplotype
Maximum likelihood method
Mitochondrion
Molecular phylogeny
Monophyly
Nonhuman
Panstrongylus
Panstrongylus chinai
Panstrongylus geniculatus
Panstrongylus howardi
Panstrongylus lignarius
Panstrongylus lutzi
Panstrongylus megistus
Panstrongylus rufotuberculatus
Panstrongylus tupynambai
Population dynamics
Population genetic structure
Ribosome
South america
Vector control
Animal
Cell nucleus
Classification
Dna sequence
Genetics
Molecular evolution
Population genetics
Ribosome dna
Animals
Cell nucleus
Mitochondria
Phylogeny
- Rights
- License
- Abierto (Texto Completo)
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dc.title.spa.fl_str_mv |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
title |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
spellingShingle |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America Animal tissue Ribosomal Population Molecular DNA Evolution Genetics Sequence analysis Bayes theorem Chagas disease Cladistics Controlled study Genetic analysis Genetic variability Geographic distribution Haplotype Maximum likelihood method Mitochondrion Molecular phylogeny Monophyly Nonhuman Panstrongylus Panstrongylus chinai Panstrongylus geniculatus Panstrongylus howardi Panstrongylus lignarius Panstrongylus lutzi Panstrongylus megistus Panstrongylus rufotuberculatus Panstrongylus tupynambai Population dynamics Population genetic structure Ribosome South america Vector control Animal Cell nucleus Classification Dna sequence Genetics Molecular evolution Population genetics Ribosome dna Animals Cell nucleus Mitochondria Phylogeny |
title_short |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
title_full |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
title_fullStr |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
title_full_unstemmed |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
title_sort |
Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America |
dc.subject.keyword.eng.fl_str_mv |
Animal tissue Ribosomal Population Molecular DNA Evolution Genetics Sequence analysis |
topic |
Animal tissue Ribosomal Population Molecular DNA Evolution Genetics Sequence analysis Bayes theorem Chagas disease Cladistics Controlled study Genetic analysis Genetic variability Geographic distribution Haplotype Maximum likelihood method Mitochondrion Molecular phylogeny Monophyly Nonhuman Panstrongylus Panstrongylus chinai Panstrongylus geniculatus Panstrongylus howardi Panstrongylus lignarius Panstrongylus lutzi Panstrongylus megistus Panstrongylus rufotuberculatus Panstrongylus tupynambai Population dynamics Population genetic structure Ribosome South america Vector control Animal Cell nucleus Classification Dna sequence Genetics Molecular evolution Population genetics Ribosome dna Animals Cell nucleus Mitochondria Phylogeny |
dc.subject.keyword.spa.fl_str_mv |
Bayes theorem Chagas disease Cladistics Controlled study Genetic analysis Genetic variability Geographic distribution Haplotype Maximum likelihood method Mitochondrion Molecular phylogeny Monophyly Nonhuman Panstrongylus Panstrongylus chinai Panstrongylus geniculatus Panstrongylus howardi Panstrongylus lignarius Panstrongylus lutzi Panstrongylus megistus Panstrongylus rufotuberculatus Panstrongylus tupynambai Population dynamics Population genetic structure Ribosome South america Vector control Animal Cell nucleus Classification Dna sequence Genetics Molecular evolution Population genetics Ribosome dna Animals Cell nucleus Mitochondria Phylogeny |
description |
Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 reported species but there is limited information about its intraspecific genetic variation and patterns of diversification. Here, we begin to fill this gap by studying populations of P. geniculatus from Colombia and Venezuela and including other epidemiologically important species from the region. We examined the pattern of diversification of P. geniculatus in Colombia using mitochondrial and nuclear ribosomal data. Genetic diversity and differentiation were calculated within and among populations of P. geniculatus. Moreover, we constructed maximum likelihood and Bayesian inference phylogenies and haplotype networks using P. geniculatus and other species from the genus (P. megistus, P. lignarius, P. lutzi, P. tupynambai, P. chinai, P. rufotuberculatus and P. howardi). Using a coalescence framework, we also dated the P. geniculatus lineages. The total evidence tree showed that P. geniculatus is a monophyletic species, with four clades that are concordant with its geographic distribution and are partly explained by the Andes orogeny. However, other factors, including anthropogenic and eco-epidemiological effects must be investigated to explain the existence of recent geographic P. geniculatus lineages. The epidemiological dynamics in structured vector populations, such as those found here, warrant further investigation. Extending our knowledge of P. geniculatus is necessary for the accurate development of effective strategies for the control of Chagas disease vectors. © 2019 Caicedo-Garzón et al. |
publishDate |
2019 |
dc.date.created.spa.fl_str_mv |
2019 |
dc.date.accessioned.none.fl_str_mv |
2020-05-25T23:58:15Z |
dc.date.available.none.fl_str_mv |
2020-05-25T23:58:15Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1371/journal.pone.0223963 |
dc.identifier.issn.none.fl_str_mv |
19326203 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/22829 |
url |
https://doi.org/10.1371/journal.pone.0223963 https://repository.urosario.edu.co/handle/10336/22829 |
identifier_str_mv |
19326203 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationIssue.none.fl_str_mv |
No. 10 |
dc.relation.citationTitle.none.fl_str_mv |
PLoS ONE |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 14 |
dc.relation.ispartof.spa.fl_str_mv |
PLoS ONE, ISSN:19326203, Vol.14, No.10 (2019) |
dc.relation.uri.spa.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073594797&doi=10.1371%2fjournal.pone.0223963&partnerID=40&md5=62acc99a547a53be2ca5f47192c4214d |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Public Library of Science |
institution |
Universidad del Rosario |
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instname:Universidad del Rosario |
dc.source.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
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578e3d3c-f2f9-46c9-b26d-a86520d46983e5615101-17e0-4e13-a841-2721ea1bd5d052085795600692a650e-7580-460c-b76f-5faadab043e7171c89ac-b54e-4c3a-aab8-479bb2ea1fa792053314-5dfc-43b3-9f93-8bb75aac525780f15593-2cd2-4c43-b949-8694a201fb2e46828995-5913-4526-ab77-9ada33b1c5c772b434cb-fa1f-42d7-a27a-5336c651f710983bcf40-821b-4d28-b42d-d80c123ee306236c768d-b09f-449f-85d3-cc4b09cb9f5c351992566007987375760010117161186002020-05-25T23:58:15Z2020-05-25T23:58:15Z2019Triatomines are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Although Triatoma and Rhodnius are the most-studied vector genera, other triatomines, such as Panstrongylus, also transmit T. cruzi, creating new epidemiological scenarios. Panstrongylus has at least 13 reported species but there is limited information about its intraspecific genetic variation and patterns of diversification. Here, we begin to fill this gap by studying populations of P. geniculatus from Colombia and Venezuela and including other epidemiologically important species from the region. We examined the pattern of diversification of P. geniculatus in Colombia using mitochondrial and nuclear ribosomal data. Genetic diversity and differentiation were calculated within and among populations of P. geniculatus. Moreover, we constructed maximum likelihood and Bayesian inference phylogenies and haplotype networks using P. geniculatus and other species from the genus (P. megistus, P. lignarius, P. lutzi, P. tupynambai, P. chinai, P. rufotuberculatus and P. howardi). Using a coalescence framework, we also dated the P. geniculatus lineages. The total evidence tree showed that P. geniculatus is a monophyletic species, with four clades that are concordant with its geographic distribution and are partly explained by the Andes orogeny. However, other factors, including anthropogenic and eco-epidemiological effects must be investigated to explain the existence of recent geographic P. geniculatus lineages. The epidemiological dynamics in structured vector populations, such as those found here, warrant further investigation. Extending our knowledge of P. geniculatus is necessary for the accurate development of effective strategies for the control of Chagas disease vectors. © 2019 Caicedo-Garzón et al.application/pdfhttps://doi.org/10.1371/journal.pone.022396319326203https://repository.urosario.edu.co/handle/10336/22829engPublic Library of ScienceNo. 10PLoS ONEVol. 14PLoS ONE, ISSN:19326203, Vol.14, No.10 (2019)https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073594797&doi=10.1371%2fjournal.pone.0223963&partnerID=40&md5=62acc99a547a53be2ca5f47192c4214dAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAnimal tissueRibosomalPopulationMolecularDNAEvolutionGeneticsSequence analysisBayes theoremChagas diseaseCladisticsControlled studyGenetic analysisGenetic variabilityGeographic distributionHaplotypeMaximum likelihood methodMitochondrionMolecular phylogenyMonophylyNonhumanPanstrongylusPanstrongylus chinaiPanstrongylus geniculatusPanstrongylus howardiPanstrongylus lignariusPanstrongylus lutziPanstrongylus megistusPanstrongylus rufotuberculatusPanstrongylus tupynambaiPopulation dynamicsPopulation genetic structureRibosomeSouth americaVector controlAnimalCell nucleusClassificationDna sequenceGeneticsMolecular evolutionPopulation geneticsRibosome dnaAnimalsCell nucleusMitochondriaPhylogenyGenetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South AmericaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Caicedo-Garzón, ValentinaSalgado-Roa, Fabian C.Galindo Hernández, CarolinaArias-Giraldo, Luisa MaríaGarcía, LinethVallejo, GustavoCantillo, OmarTovar, Catalinada Rosa, Joao AristeuCarrasco, Hernán J.Segovia, MaikellSanchez-Herrera, MelissaSalazar, CamiloRamírez, Juan DavidORIGINALjournal-pone-0223963.pdfapplication/pdf2565250https://repository.urosario.edu.co/bitstreams/9d153ea6-216e-4279-a90e-72abf83230a0/download9c768d18d6abf40660565846a6b286a6MD51TEXTjournal-pone-0223963.pdf.txtjournal-pone-0223963.pdf.txtExtracted texttext/plain58537https://repository.urosario.edu.co/bitstreams/f923c6d3-6056-4a19-a95a-f15142d364ec/download7a0076503c235f4586fd5c22946c3e28MD52THUMBNAILjournal-pone-0223963.pdf.jpgjournal-pone-0223963.pdf.jpgGenerated Thumbnailimage/jpeg4424https://repository.urosario.edu.co/bitstreams/0a918f16-97f0-4fae-b811-00451b35971c/download9c158e5404af8000ad0eb2b14e1ab4baMD5310336/22829oai:repository.urosario.edu.co:10336/228292022-08-29 09:10:03.214https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |