PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS

The neurodegenerative diseases are the result of the interaction of several factors that converge in neuronal death. Neuronalapoptosis is believe to have a mayor physiophatological role in this process which is accompanied by alterations in thevascular brain endothelium, contributing to alterations...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2009
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/28463
Acceso en línea:
https://doi.org/10.1111/j.1471-4159.2009.05818.x
https://repository.urosario.edu.co/handle/10336/28463
Palabra clave:
Neurodegenerative diseases
Neuronalapoptosis
Alterations in thevascular brain endothelium
Key regulator of neuronal survival/death equilibrium
Pathophysiology of neuronal death
Rights
License
Abierto (Texto Completo)
id EDOCUR2_9f10937e1a08460c794463f61beff194
oai_identifier_str oai:repository.urosario.edu.co:10336/28463
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 1ca29b10-a28c-4fb1-b487-d9c6e2809d6f4ff06321-c67d-4f52-a591-ef38d20c8934b92633b0-5fc6-4e99-8dd6-ce6ff75ec45815ad7c6a-7344-4c5e-9e3b-a7afb2a5d1b43104b7d2-1145-4ddd-a515-e5c7e840a50d518033546002020-08-28T15:48:15Z2020-08-28T15:48:15Z2009-02-01The neurodegenerative diseases are the result of the interaction of several factors that converge in neuronal death. Neuronalapoptosis is believe to have a mayor physiophatological role in this process which is accompanied by alterations in thevascular brain endothelium, contributing to alterations in the blood-brain barrier, a key regulator of neuronal survival/death equilibrium. Increased levels of the sphingolipid ceramide have been described in diverse neurodegenerative disorders and following several cellular stress insults and is believe to contribute to thepathophysiology of neuronal death.application/pdfhttps://doi.org/10.1111/j.1471-4159.2009.05818.xISSN: 1471-4159https://repository.urosario.edu.co/handle/10336/28463engJohn Wiley & Sons86No. 185Journal of NeurochemistryVol. 108Journal of Neurochemistry, ISSN:1471-4159, Vol. 108, Issues 1 Special Issue: Abstracts of the American Society for Neurochemistry 40th Annual Meeting 7–11 March Charleston SC USA (February, 2009); pp. 85-86https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.2009.05818.xAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Journal of Neurochemistryinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURNeurodegenerative diseasesNeuronalapoptosisAlterations in thevascular brain endotheliumKey regulator of neuronal survival/death equilibriumPathophysiology of neuronal deathPROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELSPAPEL PROTECTOR DE LA PROTEÍNA C ACTIVADA CONTRA LA APOPTOSIS EN MODELOS NEURONALES Y ENDOTELIALESarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Morales, L.C.Díaz, J.Camargo, M.H.Arboleda, H.Arboleda, G.Matheus Merino, Luisa Marina10336/28463oai:repository.urosario.edu.co:10336/284632021-09-13 01:19:09.858https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
dc.title.TranslatedTitle.spa.fl_str_mv PAPEL PROTECTOR DE LA PROTEÍNA C ACTIVADA CONTRA LA APOPTOSIS EN MODELOS NEURONALES Y ENDOTELIALES
title PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
spellingShingle PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
Neurodegenerative diseases
Neuronalapoptosis
Alterations in thevascular brain endothelium
Key regulator of neuronal survival/death equilibrium
Pathophysiology of neuronal death
title_short PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
title_full PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
title_fullStr PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
title_full_unstemmed PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
title_sort PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS
dc.subject.keyword.spa.fl_str_mv Neurodegenerative diseases
Neuronalapoptosis
Alterations in thevascular brain endothelium
Key regulator of neuronal survival/death equilibrium
Pathophysiology of neuronal death
topic Neurodegenerative diseases
Neuronalapoptosis
Alterations in thevascular brain endothelium
Key regulator of neuronal survival/death equilibrium
Pathophysiology of neuronal death
description The neurodegenerative diseases are the result of the interaction of several factors that converge in neuronal death. Neuronalapoptosis is believe to have a mayor physiophatological role in this process which is accompanied by alterations in thevascular brain endothelium, contributing to alterations in the blood-brain barrier, a key regulator of neuronal survival/death equilibrium. Increased levels of the sphingolipid ceramide have been described in diverse neurodegenerative disorders and following several cellular stress insults and is believe to contribute to thepathophysiology of neuronal death.
publishDate 2009
dc.date.created.spa.fl_str_mv 2009-02-01
dc.date.accessioned.none.fl_str_mv 2020-08-28T15:48:15Z
dc.date.available.none.fl_str_mv 2020-08-28T15:48:15Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1111/j.1471-4159.2009.05818.x
dc.identifier.issn.none.fl_str_mv ISSN: 1471-4159
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/28463
url https://doi.org/10.1111/j.1471-4159.2009.05818.x
https://repository.urosario.edu.co/handle/10336/28463
identifier_str_mv ISSN: 1471-4159
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 86
dc.relation.citationIssue.none.fl_str_mv No. 1
dc.relation.citationStartPage.none.fl_str_mv 85
dc.relation.citationTitle.none.fl_str_mv Journal of Neurochemistry
dc.relation.citationVolume.none.fl_str_mv Vol. 108
dc.relation.ispartof.spa.fl_str_mv Journal of Neurochemistry, ISSN:1471-4159, Vol. 108, Issues 1 Special Issue: Abstracts of the American Society for Neurochemistry 40th Annual Meeting 7–11 March Charleston SC USA (February, 2009); pp. 85-86
dc.relation.uri.spa.fl_str_mv https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.2009.05818.x
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv John Wiley & Sons
dc.source.spa.fl_str_mv Journal of Neurochemistry
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
_version_ 1808390974146084864

Publicaciones similares