Paracoccidioidomycosis: Latin America's own fungal disorder
Paracoccidioidomycosis (PCM) is a systemic, endemic fungal disorder restricted to Latin America (Mexico to Argentina); Brazil accounts for the largest number of cases. Imported cases diagnosed in North America, Europe and Asia represent patients who had previously lived in recognized endemic areas....
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2012
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/23805
- Acceso en línea:
- https://doi.org/10.1007/s12281-012-0114-x
https://repository.urosario.edu.co/handle/10336/23805
- Palabra clave:
- Amphotericin B
Amphotericin B deoxycholate
Amphotericin B lipid complex
Antifungal agent
Corticosteroid
Cotrimoxazole
Fluconazole
Fungus antigen
Itraconazole
Ketoconazole
Pyrrole derivative
Ribosome RNA
Sulfonamide
Voriconazole
Agriculture
Alcoholism
Antigen recognition
Article
Brazil
Cause of death
Clinical examination
Clinical feature
Complement fixation test
Conidium
Diagnostic test
Differential diagnosis
Disease course
Dot hybridization
Drug efficacy
Drug safety
Drug treatment failure
Environmental temperature
Enzyme linked immunosorbent assay
Fungal gene
Fungus culture
Fungus identification
Histopathology
Human
Immunodiffusion
Incidence
Loop mediated isothermal amplification
Lower respiratory tract infection
Lung fibrosis
Molecular diagnosis
Nonhuman
Nutrition
Occupational exposure
Paracoccidioides brasiliensis
Pneumonia
Quality of life
Race
Real time polymerase chain reaction
Recurrent infection
RNA gene
Sensitivity and specificity
Serodiagnosis
Sex difference
Smoking
South American blastomycosis
Survival
Unspecified side effect
Western blotting
Acute/subacute paracoccidioidomycosis
Chronic
Endemic areas
Laboratory diagnosis
Latency
Management
Paracoccidioides brasiliensis
Paracoccidioidomycosis
South American Blastomycosis
- Rights
- License
- Abierto (Texto Completo)
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5a9ddfa9-4c89-466e-8675-4d15387b76ce-11598a9c7-daee-42c6-83bf-7ddb0e350ad6-1107a9ddf-a426-44b3-88e8-6c1c1a4eec54-12020-05-26T00:05:34Z2020-05-26T00:05:34Z2012Paracoccidioidomycosis (PCM) is a systemic, endemic fungal disorder restricted to Latin America (Mexico to Argentina); Brazil accounts for the largest number of cases. Imported cases diagnosed in North America, Europe and Asia represent patients who had previously lived in recognized endemic areas. Paracoccidioides brasiliensis, the etiologic agent, is a thermally dimorphic fungus that in patients and cultures at 37 C adopts a yeast form while at lower temperatures it behaves as a mold that bears the infectious conidia. PCM has a peculiar gender distribution with preference for adult males at a ratio of ?11 to 1. PCM afflicts predominantly adult males engaged in agriculture. It is mostly a chronic disease with acute/subacute cases accounting for less than 15 % of all reports. Specific diagnosis is established late and although available therapy is usually successful in controlling the fungal infection, patients who survive usually develop residual fibrotic lesions that heavily impair their quality of life. © 2012 Springer Science+Business Media New York.application/pdfhttps://doi.org/10.1007/s12281-012-0114-x193637611936377Xhttps://repository.urosario.edu.co/handle/10336/23805eng311No. 4303Current Fungal Infection ReportsVol. 6Current Fungal Infection Reports, ISSN:19363761, 1936377X, Vol.6, No.4 (2012); pp. 303-311https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884140711&doi=10.1007%2fs12281-012-0114-x&partnerID=40&md5=1ab43dd244b1313c259870a7d3d1d4edAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAmphotericin BAmphotericin B deoxycholateAmphotericin B lipid complexAntifungal agentCorticosteroidCotrimoxazoleFluconazoleFungus antigenItraconazoleKetoconazolePyrrole derivativeRibosome RNASulfonamideVoriconazoleAgricultureAlcoholismAntigen recognitionArticleBrazilCause of deathClinical examinationClinical featureComplement fixation testConidiumDiagnostic testDifferential diagnosisDisease courseDot hybridizationDrug efficacyDrug safetyDrug treatment failureEnvironmental temperatureEnzyme linked immunosorbent assayFungal geneFungus cultureFungus identificationHistopathologyHumanImmunodiffusionIncidenceLoop mediated isothermal amplificationLower respiratory tract infectionLung fibrosisMolecular diagnosisNonhumanNutritionOccupational exposureParacoccidioides brasiliensisPneumoniaQuality of lifeRaceReal time polymerase chain reactionRecurrent infectionRNA geneSensitivity and specificitySerodiagnosisSex differenceSmokingSouth American blastomycosisSurvivalUnspecified side effectWestern blottingAcute/subacute paracoccidioidomycosisChronicEndemic areasLaboratory diagnosisLatencyManagementParacoccidioides brasiliensisParacoccidioidomycosisSouth American BlastomycosisParacoccidioidomycosis: Latin America's own fungal disorderarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Restrepo, AngelaGómez, Beatriz L.Tobón, AngelaORIGINALParacoccidioidomycosis_Latin_America_s_O.pdfapplication/pdf243777https://repository.urosario.edu.co/bitstreams/5a51b5f6-fda9-43db-858d-b2872cd09e99/download0c4ab29c529d754c68d4c98a7dd9a81dMD51TEXTParacoccidioidomycosis_Latin_America_s_O.pdf.txtParacoccidioidomycosis_Latin_America_s_O.pdf.txtExtracted texttext/plain52969https://repository.urosario.edu.co/bitstreams/02ec4043-8477-4e17-bf26-63c1c09771f0/download2f58ba411d76e8d9cfd6d8f57813c11fMD52THUMBNAILParacoccidioidomycosis_Latin_America_s_O.pdf.jpgParacoccidioidomycosis_Latin_America_s_O.pdf.jpgGenerated Thumbnailimage/jpeg4305https://repository.urosario.edu.co/bitstreams/8786f7f0-89bc-4b5d-97d9-027fcca9286e/download0d5ab8248ef71b94bf8f34bb16c03f8eMD5310336/23805oai:repository.urosario.edu.co:10336/238052022-05-02 07:37:21.217945https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
Paracoccidioidomycosis: Latin America's own fungal disorder |
title |
Paracoccidioidomycosis: Latin America's own fungal disorder |
spellingShingle |
Paracoccidioidomycosis: Latin America's own fungal disorder Amphotericin B Amphotericin B deoxycholate Amphotericin B lipid complex Antifungal agent Corticosteroid Cotrimoxazole Fluconazole Fungus antigen Itraconazole Ketoconazole Pyrrole derivative Ribosome RNA Sulfonamide Voriconazole Agriculture Alcoholism Antigen recognition Article Brazil Cause of death Clinical examination Clinical feature Complement fixation test Conidium Diagnostic test Differential diagnosis Disease course Dot hybridization Drug efficacy Drug safety Drug treatment failure Environmental temperature Enzyme linked immunosorbent assay Fungal gene Fungus culture Fungus identification Histopathology Human Immunodiffusion Incidence Loop mediated isothermal amplification Lower respiratory tract infection Lung fibrosis Molecular diagnosis Nonhuman Nutrition Occupational exposure Paracoccidioides brasiliensis Pneumonia Quality of life Race Real time polymerase chain reaction Recurrent infection RNA gene Sensitivity and specificity Serodiagnosis Sex difference Smoking South American blastomycosis Survival Unspecified side effect Western blotting Acute/subacute paracoccidioidomycosis Chronic Endemic areas Laboratory diagnosis Latency Management Paracoccidioides brasiliensis Paracoccidioidomycosis South American Blastomycosis |
title_short |
Paracoccidioidomycosis: Latin America's own fungal disorder |
title_full |
Paracoccidioidomycosis: Latin America's own fungal disorder |
title_fullStr |
Paracoccidioidomycosis: Latin America's own fungal disorder |
title_full_unstemmed |
Paracoccidioidomycosis: Latin America's own fungal disorder |
title_sort |
Paracoccidioidomycosis: Latin America's own fungal disorder |
dc.subject.keyword.spa.fl_str_mv |
Amphotericin B Amphotericin B deoxycholate Amphotericin B lipid complex Antifungal agent Corticosteroid Cotrimoxazole Fluconazole Fungus antigen Itraconazole Ketoconazole Pyrrole derivative Ribosome RNA Sulfonamide Voriconazole Agriculture Alcoholism Antigen recognition Article Brazil Cause of death Clinical examination Clinical feature Complement fixation test Conidium Diagnostic test Differential diagnosis Disease course Dot hybridization Drug efficacy Drug safety Drug treatment failure Environmental temperature Enzyme linked immunosorbent assay Fungal gene Fungus culture Fungus identification Histopathology Human Immunodiffusion Incidence Loop mediated isothermal amplification Lower respiratory tract infection Lung fibrosis Molecular diagnosis Nonhuman Nutrition Occupational exposure Paracoccidioides brasiliensis Pneumonia Quality of life Race Real time polymerase chain reaction Recurrent infection RNA gene Sensitivity and specificity Serodiagnosis Sex difference Smoking South American blastomycosis Survival Unspecified side effect Western blotting Acute/subacute paracoccidioidomycosis Chronic Endemic areas Laboratory diagnosis Latency Management Paracoccidioides brasiliensis Paracoccidioidomycosis South American Blastomycosis |
topic |
Amphotericin B Amphotericin B deoxycholate Amphotericin B lipid complex Antifungal agent Corticosteroid Cotrimoxazole Fluconazole Fungus antigen Itraconazole Ketoconazole Pyrrole derivative Ribosome RNA Sulfonamide Voriconazole Agriculture Alcoholism Antigen recognition Article Brazil Cause of death Clinical examination Clinical feature Complement fixation test Conidium Diagnostic test Differential diagnosis Disease course Dot hybridization Drug efficacy Drug safety Drug treatment failure Environmental temperature Enzyme linked immunosorbent assay Fungal gene Fungus culture Fungus identification Histopathology Human Immunodiffusion Incidence Loop mediated isothermal amplification Lower respiratory tract infection Lung fibrosis Molecular diagnosis Nonhuman Nutrition Occupational exposure Paracoccidioides brasiliensis Pneumonia Quality of life Race Real time polymerase chain reaction Recurrent infection RNA gene Sensitivity and specificity Serodiagnosis Sex difference Smoking South American blastomycosis Survival Unspecified side effect Western blotting Acute/subacute paracoccidioidomycosis Chronic Endemic areas Laboratory diagnosis Latency Management Paracoccidioides brasiliensis Paracoccidioidomycosis South American Blastomycosis |
description |
Paracoccidioidomycosis (PCM) is a systemic, endemic fungal disorder restricted to Latin America (Mexico to Argentina); Brazil accounts for the largest number of cases. Imported cases diagnosed in North America, Europe and Asia represent patients who had previously lived in recognized endemic areas. Paracoccidioides brasiliensis, the etiologic agent, is a thermally dimorphic fungus that in patients and cultures at 37 C adopts a yeast form while at lower temperatures it behaves as a mold that bears the infectious conidia. PCM has a peculiar gender distribution with preference for adult males at a ratio of ?11 to 1. PCM afflicts predominantly adult males engaged in agriculture. It is mostly a chronic disease with acute/subacute cases accounting for less than 15 % of all reports. Specific diagnosis is established late and although available therapy is usually successful in controlling the fungal infection, patients who survive usually develop residual fibrotic lesions that heavily impair their quality of life. © 2012 Springer Science+Business Media New York. |
publishDate |
2012 |
dc.date.created.spa.fl_str_mv |
2012 |
dc.date.accessioned.none.fl_str_mv |
2020-05-26T00:05:34Z |
dc.date.available.none.fl_str_mv |
2020-05-26T00:05:34Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1007/s12281-012-0114-x |
dc.identifier.issn.none.fl_str_mv |
19363761 1936377X |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/23805 |
url |
https://doi.org/10.1007/s12281-012-0114-x https://repository.urosario.edu.co/handle/10336/23805 |
identifier_str_mv |
19363761 1936377X |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
311 |
dc.relation.citationIssue.none.fl_str_mv |
No. 4 |
dc.relation.citationStartPage.none.fl_str_mv |
303 |
dc.relation.citationTitle.none.fl_str_mv |
Current Fungal Infection Reports |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 6 |
dc.relation.ispartof.spa.fl_str_mv |
Current Fungal Infection Reports, ISSN:19363761, 1936377X, Vol.6, No.4 (2012); pp. 303-311 |
dc.relation.uri.spa.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884140711&doi=10.1007%2fs12281-012-0114-x&partnerID=40&md5=1ab43dd244b1313c259870a7d3d1d4ed |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
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Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
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