Colonization and infection in the newborn infant: Does chlorhexidine play a role in infection prevention

Healthcare-Associated infections are a major problem in newborn infants, considering their high morbidity, mortality, and long-Term sequelae. In preterm infants, it has been shown that skin and gastrointestinal tract colonization undergoes variations compared to healthy term infants, and that preterm infants are more exposed to nosocomial microorganisms given their higher probability of being admitted to the neonatal intensive care unit where they are cared for. This document reviews normal colonization, the changes observed during hospitalization, prematurity, and the potential role of chlorhexidine in the prevention of resistant microorganism transmission, as well as its side effects in newborn infants admitted to the neonatal intensive care unit.

• Fecha de publicación: 2017
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/22811
• Acceso en línea: https://doi.org/10.5546/aap.2017.eng.65; https://repository.urosario.edu.co/handle/10336/22811
• Palabra clave: Chlorhexidine; Chlorhexidine; Topical antiinfective agent; Article; Bacterial colonization; Bacteroides; Bifidobacteriaceae; Bifidobacterium; Brain toxicity; Child hospitalization; Clostridium; Contact dermatitis; Corynebacterium; Disease transmission; Enterobacteriaceae; Enterococcus; Erosion; Erythema; Follow up; Gestational age; Health program; Health survey; Healthcare associated infection; Hospitalization; Human; Infection prevention; Intestine flora; Lactobacillus; Long term care; Neonatal intensive care unit; Newborn; Newborn infection; Newborn morbidity; Newborn mortality; Newborn sepsis; Nonhuman; Prematurity; Prevotella; Propionibacterium; Skin manifestation; Staphylococcus; Cross infection; Gastrointestinal tract; Microbiology; Skin; Chlorhexidine; Cross infection; Gastrointestinal tract; Humans; Skin; Chlorhexidine; Nosocomial infection; Preterm infant; Primary prevention; Sepsis; newborn; local; Anti-infective agents; Infant
• License: Abierto (Texto Completo)