Vitamin C Mega Dose vs. Standard Dose in Smokers with Subclinical Hypovitaminosis C, A Controlled Randomized Clinical Trial - a short review
Smoking induces oxidative stress, which is associated with lower plasma Vitamin C levels. Adult smokers in Bogota, Colombia were randomly recruited into 2 groups, a megadose Vitamin C group (Day 1, 15g IV, Day 2, 15g IV, One gram orally for 2 weeks after) and a standard dose Vitamin C group (Day 1,...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2008
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/27204
- Acceso en línea:
- https://repository.urosario.edu.co/handle/10336/27204
- Palabra clave:
- Smoking
Oxidative stress
Plasma
Vitamin C
Haemoglobin
Haematocrit
- Rights
- License
- Abierto (Texto Completo)
| Summary: | Smoking induces oxidative stress, which is associated with lower plasma Vitamin C levels. Adult smokers in Bogota, Colombia were randomly recruited into 2 groups, a megadose Vitamin C group (Day 1, 15g IV, Day 2, 15g IV, One gram orally for 2 weeks after) and a standard dose Vitamin C group (Day 1, 100mg IV, Day 2 100mg IV). The study was double blinded. Urine Vitamin C, haemoglobin and haematocrit were measured pre and post intervention in both groups. Results: At the end of the study Haematocrit and Haemoglobin levels were lowered significantly in the megadose group. C-LDL was not significantly different between the groups. Urine Vitamin C was raised in both groups. |
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