Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis

Ocular toxoplasmosis is the most common infectious cause of retinochoroidal inflammation in immunocompetent individuals and is one of the most important causes of visual damage in some countries.1 Thus, in Colombia, it is estimated that 6% of the population has retinochoroidal scars after a non cong...

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Tipo de recurso:
Fecha de publicación:
2012
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/26422
Acceso en línea:
https://doi.org/10.1016/j.jmii.2011.09.003
https://repository.urosario.edu.co/handle/10336/26422
Palabra clave:
Chorioretinitis
Dehydroepiandrostenione hormones
Toxoplasmosis
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spelling 51701355600d8458cdd-1984-41c6-a599-fc399a74830d378cf710-3feb-49c9-a0db-6e1b114893c9cd731e04-20b4-454f-9410-3c396ccdc55776d3629d-cffa-408d-91db-15cf139af24b2020-08-06T16:21:39Z2020-08-06T16:21:39Z2012-02Ocular toxoplasmosis is the most common infectious cause of retinochoroidal inflammation in immunocompetent individuals and is one of the most important causes of visual damage in some countries.1 Thus, in Colombia, it is estimated that 6% of the population has retinochoroidal scars after a non congenital infection and 20% of these persons have reduced visual capacity.2 Recurrent retinochoroiditis is a typical characteristic of ocular toxoplasmosis and the factors related to this remain to be discovered.3 In a field study in Brazil, a relation between puberty, gender and apparition of new lesions in ocular toxoplasmosis was described.4 A hormonal factor triggering recurrences has been evocated but the precise hormones linked to these events have not been studied. In recent years there has been strong speculation that puberty-related hormones, dehydroepiandrosterone (DHEA) in particular, might play some role in inducing resistance during Schistosoma, HIV and malaria infections.5, 6, 7 DHEA is one of the steroid hormones produced by the adrenal cortex and is found mostly in its sulfate form, DHEA sulfate (DHEAS); it is converted to DHEA by DHEA sulfatase.8 The secretion of DHEAS is high just before birth and again at puberty, and the maximum concentration is reached at around 20 to 30 years of age, followed by a progressive decline with age. DHEAS is implicated in age-related changes in the immune system and has been associated with disease susceptibility.9 To our knowledge, no report has been made of the DHEAS levels during human toxoplasmosis.application/pdfhttps://doi.org/10.1016/j.jmii.2011.09.003ISSN: 1684-1182EISSN: 1995-9133https://repository.urosario.edu.co/handle/10336/26422engTaiwan Society of MicrobiologyElsevier68No. 165Journal of Microbiology, Immunology and InfectionVol. 45Journal of Microbiology, Immunology and Infection, ISSN: 1684-1182;EISSN: 1995-9133, Vol.45, No.1 (2012); pp.65-68https://www.sciencedirect.com/science/article/pii/S1684118211001587Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Journal of Microbiology, Immunology and Infectioninstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURChorioretinitisDehydroepiandrostenione hormonesToxoplasmosisSerum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosisNiveles séricos de sulfato de dehidroepiandrosterona (DHEAS) en toxoplasmosis oculararticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501de-la-Torre, AlejandraRíos-Cadavid, Angela CristinaCardozo-García, Carlos MarioPadilla, LeonardoGómez-Marín, Jorge EnriqueORIGINAL1-s2-0-S1684118211001587-main.pdfapplication/pdf211400https://repository.urosario.edu.co/bitstreams/d91f37fa-41d9-4ab6-9124-abeb4aa562d2/download57bc7eb9927dc8cf2ec590ee80befd7cMD51TEXT1-s2-0-S1684118211001587-main.pdf.txt1-s2-0-S1684118211001587-main.pdf.txtExtracted texttext/plain11313https://repository.urosario.edu.co/bitstreams/c7662182-b5c6-4a67-8a5c-555cce4109fe/downloadf48ae790ba5e52ab9322ceaf5a88b276MD52THUMBNAIL1-s2-0-S1684118211001587-main.pdf.jpg1-s2-0-S1684118211001587-main.pdf.jpgGenerated Thumbnailimage/jpeg4643https://repository.urosario.edu.co/bitstreams/89106861-ab72-4479-ba59-d72820c6026a/download74c6d389fa6f33c3cc0069766b8ae33eMD5310336/26422oai:repository.urosario.edu.co:10336/264222022-05-02 07:37:15.932168https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
dc.title.TranslatedTitle.spa.fl_str_mv Niveles séricos de sulfato de dehidroepiandrosterona (DHEAS) en toxoplasmosis ocular
title Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
spellingShingle Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
Chorioretinitis
Dehydroepiandrostenione hormones
Toxoplasmosis
title_short Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
title_full Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
title_fullStr Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
title_full_unstemmed Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
title_sort Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis
dc.subject.keyword.spa.fl_str_mv Chorioretinitis
Dehydroepiandrostenione hormones
Toxoplasmosis
topic Chorioretinitis
Dehydroepiandrostenione hormones
Toxoplasmosis
description Ocular toxoplasmosis is the most common infectious cause of retinochoroidal inflammation in immunocompetent individuals and is one of the most important causes of visual damage in some countries.1 Thus, in Colombia, it is estimated that 6% of the population has retinochoroidal scars after a non congenital infection and 20% of these persons have reduced visual capacity.2 Recurrent retinochoroiditis is a typical characteristic of ocular toxoplasmosis and the factors related to this remain to be discovered.3 In a field study in Brazil, a relation between puberty, gender and apparition of new lesions in ocular toxoplasmosis was described.4 A hormonal factor triggering recurrences has been evocated but the precise hormones linked to these events have not been studied. In recent years there has been strong speculation that puberty-related hormones, dehydroepiandrosterone (DHEA) in particular, might play some role in inducing resistance during Schistosoma, HIV and malaria infections.5, 6, 7 DHEA is one of the steroid hormones produced by the adrenal cortex and is found mostly in its sulfate form, DHEA sulfate (DHEAS); it is converted to DHEA by DHEA sulfatase.8 The secretion of DHEAS is high just before birth and again at puberty, and the maximum concentration is reached at around 20 to 30 years of age, followed by a progressive decline with age. DHEAS is implicated in age-related changes in the immune system and has been associated with disease susceptibility.9 To our knowledge, no report has been made of the DHEAS levels during human toxoplasmosis.
publishDate 2012
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dc.date.accessioned.none.fl_str_mv 2020-08-06T16:21:39Z
dc.date.available.none.fl_str_mv 2020-08-06T16:21:39Z
dc.type.eng.fl_str_mv article
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dc.type.spa.spa.fl_str_mv Artículo
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dc.identifier.issn.none.fl_str_mv ISSN: 1684-1182
EISSN: 1995-9133
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/26422
url https://doi.org/10.1016/j.jmii.2011.09.003
https://repository.urosario.edu.co/handle/10336/26422
identifier_str_mv ISSN: 1684-1182
EISSN: 1995-9133
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dc.relation.citationIssue.none.fl_str_mv No. 1
dc.relation.citationStartPage.none.fl_str_mv 65
dc.relation.citationTitle.none.fl_str_mv Journal of Microbiology, Immunology and Infection
dc.relation.citationVolume.none.fl_str_mv Vol. 45
dc.relation.ispartof.spa.fl_str_mv Journal of Microbiology, Immunology and Infection, ISSN: 1684-1182;EISSN: 1995-9133, Vol.45, No.1 (2012); pp.65-68
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dc.publisher.spa.fl_str_mv Taiwan Society of Microbiology
Elsevier
dc.source.spa.fl_str_mv Journal of Microbiology, Immunology and Infection
institution Universidad del Rosario
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