Uso perioperatorio del nefopam: Revisión sistemática cualitativa

El nefopam es un analgésico no opioide, no AINE, derivado de la benzoxazocina con efecto de acción central, con múltiples mecanismos de acción que ha sido usado recientemente como analgésico perioperatorio. Llevamos a cabo una revisión sistemática de la literatura para evaluar la eficacia del nefopa...

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Tipo de recurso:
Fecha de publicación:
2023
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
spa
OAI Identifier:
oai:repository.urosario.edu.co:10336/40215
Acceso en línea:
https://doi.org/10.48713/10336_40215
https://repository.urosario.edu.co/handle/10336/40215
Palabra clave:
Analgésicos
Cirugía
Procedimientos quirúrgicos
Nefopam
Acupan
Analgesia postoperatoria
Dolor postoperatorio
Analgésicos no opioides
Técnicas analgésicas
Nefopam clorhidrato
Analgesics
Surgery
Procedure, surgical
Nefopam
Acupan
Analgesia, postoperative
Pain, postoperative
Analgesics non-opioid
Analgesic techniques
Nefopam hydrochloride
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id EDOCUR2_7cdc86fb9dae0ea1ee3c0b08a6320139
oai_identifier_str oai:repository.urosario.edu.co:10336/40215
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.none.fl_str_mv Uso perioperatorio del nefopam: Revisión sistemática cualitativa
dc.title.TranslatedTitle.none.fl_str_mv Perioperative use of nefopam: Qualitative systematic review
title Uso perioperatorio del nefopam: Revisión sistemática cualitativa
spellingShingle Uso perioperatorio del nefopam: Revisión sistemática cualitativa
Analgésicos
Cirugía
Procedimientos quirúrgicos
Nefopam
Acupan
Analgesia postoperatoria
Dolor postoperatorio
Analgésicos no opioides
Técnicas analgésicas
Nefopam clorhidrato
Analgesics
Surgery
Procedure, surgical
Nefopam
Acupan
Analgesia, postoperative
Pain, postoperative
Analgesics non-opioid
Analgesic techniques
Nefopam hydrochloride
title_short Uso perioperatorio del nefopam: Revisión sistemática cualitativa
title_full Uso perioperatorio del nefopam: Revisión sistemática cualitativa
title_fullStr Uso perioperatorio del nefopam: Revisión sistemática cualitativa
title_full_unstemmed Uso perioperatorio del nefopam: Revisión sistemática cualitativa
title_sort Uso perioperatorio del nefopam: Revisión sistemática cualitativa
dc.contributor.advisor.none.fl_str_mv García Cespedes, Javier
dc.subject.none.fl_str_mv Analgésicos
Cirugía
Procedimientos quirúrgicos
Nefopam
Acupan
Analgesia postoperatoria
Dolor postoperatorio
Analgésicos no opioides
Técnicas analgésicas
Nefopam clorhidrato
topic Analgésicos
Cirugía
Procedimientos quirúrgicos
Nefopam
Acupan
Analgesia postoperatoria
Dolor postoperatorio
Analgésicos no opioides
Técnicas analgésicas
Nefopam clorhidrato
Analgesics
Surgery
Procedure, surgical
Nefopam
Acupan
Analgesia, postoperative
Pain, postoperative
Analgesics non-opioid
Analgesic techniques
Nefopam hydrochloride
dc.subject.keyword.none.fl_str_mv Analgesics
Surgery
Procedure, surgical
Nefopam
Acupan
Analgesia, postoperative
Pain, postoperative
Analgesics non-opioid
Analgesic techniques
Nefopam hydrochloride
description El nefopam es un analgésico no opioide, no AINE, derivado de la benzoxazocina con efecto de acción central, con múltiples mecanismos de acción que ha sido usado recientemente como analgésico perioperatorio. Llevamos a cabo una revisión sistemática de la literatura para evaluar la eficacia del nefopam en manejo de dolor postoperatorio. Aplicando la estrategia de búsqueda en 5 bases de datos (Embase, LiLACS, ProQuest, Pubmed y Scopus), se obtuvieron 684 articulos, después de la revisión se incluyeron 19 articulos del nefopam en monoterapia y 13 articulos del nefopam usado junto a otros medicamentos. En cuanto a eficacia analgésica el nefopam no demostró ser superior a otros medicamentos, pero su uso combinado si disminuyo el consumo de opioide perioperatorio en el cerca de la mitad de los estudios. En conclusión, el nefopam puede ser usado como un fármaco adicional al manejo analgésico actual más que como reemplazo de los mismos, con el fin de reducir el consumo de opioides perioperatorios o en pacientes con contraindicación para otros analgésicos.
publishDate 2023
dc.date.accessioned.none.fl_str_mv 2023-07-24T18:59:29Z
dc.date.available.none.fl_str_mv 2023-07-24T18:59:29Z
dc.date.created.none.fl_str_mv 2023-07-19
dc.date.embargoEnd.none.fl_str_mv info:eu-repo/date/embargoEnd/2025-07-26
dc.type.none.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.none.fl_str_mv Revisión sistemática
dc.type.spa.none.fl_str_mv Trabajo de grado
dc.identifier.doi.none.fl_str_mv https://doi.org/10.48713/10336_40215
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/40215
url https://doi.org/10.48713/10336_40215
https://repository.urosario.edu.co/handle/10336/40215
dc.language.iso.none.fl_str_mv spa
language spa
dc.rights.*.fl_str_mv Attribution-NonCommercial-ShareAlike 4.0 International
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.acceso.none.fl_str_mv Restringido (Temporalmente bloqueado)
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
rights_invalid_str_mv Attribution-NonCommercial-ShareAlike 4.0 International
Restringido (Temporalmente bloqueado)
http://creativecommons.org/licenses/by-nc-sa/4.0/
http://purl.org/coar/access_right/c_f1cf
dc.format.extent.none.fl_str_mv 76
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad del Rosario
dc.publisher.department.spa.fl_str_mv Escuela de Medicina y Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Maestría en Epidemiología
institution Universidad del Rosario
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spelling García Cespedes, Javier3be50207-fd76-4c63-9bc5-bd0df084e741-1Durán Mendoza, Edgar AndrésPardo Fonseca, Manuel FelipeMagíster en EpidemiologíaMaestríaFull time24d1a30f-f2dc-486e-8437-8fabcb468788-16dba6bf1-65d4-4c9c-9fcb-46b740e3c2ab-12023-07-24T18:59:29Z2023-07-24T18:59:29Z2023-07-19info:eu-repo/date/embargoEnd/2025-07-26El nefopam es un analgésico no opioide, no AINE, derivado de la benzoxazocina con efecto de acción central, con múltiples mecanismos de acción que ha sido usado recientemente como analgésico perioperatorio. Llevamos a cabo una revisión sistemática de la literatura para evaluar la eficacia del nefopam en manejo de dolor postoperatorio. Aplicando la estrategia de búsqueda en 5 bases de datos (Embase, LiLACS, ProQuest, Pubmed y Scopus), se obtuvieron 684 articulos, después de la revisión se incluyeron 19 articulos del nefopam en monoterapia y 13 articulos del nefopam usado junto a otros medicamentos. En cuanto a eficacia analgésica el nefopam no demostró ser superior a otros medicamentos, pero su uso combinado si disminuyo el consumo de opioide perioperatorio en el cerca de la mitad de los estudios. En conclusión, el nefopam puede ser usado como un fármaco adicional al manejo analgésico actual más que como reemplazo de los mismos, con el fin de reducir el consumo de opioides perioperatorios o en pacientes con contraindicación para otros analgésicos.Nefopam is a non-opioid, non-NSAID, centrally acting benzoxazocine derivative analgesic with multiple mechanisms of action that has recently been used as a perioperative analgesic. We conducted a systematic literatura review to evaluate the efficacy of nefopam in postoperative pain management. Applying the search strategy in 5 databases (Embase, LiLACS, ProQuest, Pubmed and Scopus), 684 articles were obtained. After the review, 19 articles on nefopam in monotherapy and 13 articles on nefopam used together with other drugs were included. Regarding analgesic efficacy, nefopam did not prove to be superior to other drugs, but its combined use did reduce perioperative opioid consumption in nearly half of the studies. In conclusion, nefopam can be used as an additional drug to current analgesic management, rather than as a replacement, in order to reduce the consumption of perioperative opioids or in patients with contraindications for other analgesics.76application/pdfhttps://doi.org/10.48713/10336_40215 https://repository.urosario.edu.co/handle/10336/40215spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludMaestría en EpidemiologíaAttribution-NonCommercial-ShareAlike 4.0 InternationalRestringido (Temporalmente bloqueado)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.http://creativecommons.org/licenses/by-nc-sa/4.0/http://purl.org/coar/access_right/c_f1cf Netter's Atlas of Neuroscience, 3e. Consultado en: 2023/03/10/21:42:31. Disponible en: http://www.pdfdrive.com/netters-atlas-of-neuroscience-3e-e175301407.html. 9781437737912: Interventional and Neuromodulatory Techniques for Pain Management Series. Consultado en: 2023/03/10/22:05:25. Disponible en: https://www.abebooks.com/9781437737912/Interventional-Neuromodulatory-Techniques-Pain-Management-1437737919/plp.Kim, B. G.; Moon, J. Y.; Choi, J. Y.; Park, I. S.; Oh, A. Y.; Jeon, Y. T.; Hwang, J. W.; Ryu, J. H. 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