Sequence analysis of the CDKN1B gene in patients with premature ovarian failure reveals a novel mutation potentially related to the phenotype

Earlier reports demonstrated a key role of Cdkn1b during mouse ovarian development. In this study, the sequencing analysis of the complete coding region of this gene in a panel of premature ovarian failure patients and control subjects reveals a novel mutation potentially related to the phenotype. © 2011 by American Society for Reproductive Medicine.

• Fecha de publicación: 2011
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/24059
• Acceso en línea: https://doi.org/10.1016/j.fertnstert.2011.04.045; https://repository.urosario.edu.co/handle/10336/24059
• Palabra clave: Cyclin dependent kinase inhibitor 1B; Follitropin; Adult; Article; Autoimmune disease; Controlled study; Female; Female infertility; Follitropin blood level; Gene mutation; Genetic analysis; Genetic code; Human; Informed consent; Karyotype; Major clinical study; Ovary development; Ovary insufficiency; Pelvis surgery; Phenotype; Premature ovarian failure; Priority journal; Sequence analysis; Single nucleotide polymorphism; CDKN1B; Mutations; Premature ovarian failure (POF); Sequencing
• License: Abierto (Texto Completo)