Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several h...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/20261
- Acceso en línea:
- https://repository.urosario.edu.co/handle/10336/20261
- Palabra clave:
- Adolescent
Adolescent Obesity
Cardiovascular Disease
Colombia
Controlled Study
Endurance Training
Energy Expenditure
Exercise
Fatty Liver
Human
Lifting Effort
Liver Metabolism
Parallel Design
Physical Activity
Physical Education
Randomized Controlled Trial
Randomized Controlled Trial (Topic)
Resistance Training
Running
Single Blind Procedure
Wrestling
Enfermedad cardiovascular
Obesidad
Enfermedades
Article
Ejercicio físico
Trastornos del metabolismo
Obesidad
Higado graso
- Rights
- License
- Abierto (Texto Completo)
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Repositorio EdocUR - U. Rosario |
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|
dc.title.spa.fl_str_mv |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
title |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
spellingShingle |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial Adolescent Adolescent Obesity Cardiovascular Disease Colombia Controlled Study Endurance Training Energy Expenditure Exercise Fatty Liver Human Lifting Effort Liver Metabolism Parallel Design Physical Activity Physical Education Randomized Controlled Trial Randomized Controlled Trial (Topic) Resistance Training Running Single Blind Procedure Wrestling Enfermedad cardiovascular Obesidad Enfermedades Article Ejercicio físico Trastornos del metabolismo Obesidad Higado graso |
title_short |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
title_full |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
title_fullStr |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
title_full_unstemmed |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
title_sort |
Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial |
dc.subject.spa.fl_str_mv |
Adolescent Adolescent Obesity Cardiovascular Disease Colombia Controlled Study Endurance Training Energy Expenditure Exercise Fatty Liver Human Lifting Effort Liver Metabolism Parallel Design Physical Activity Physical Education Randomized Controlled Trial Randomized Controlled Trial (Topic) Resistance Training Running Single Blind Procedure Wrestling Enfermedad cardiovascular Obesidad |
topic |
Adolescent Adolescent Obesity Cardiovascular Disease Colombia Controlled Study Endurance Training Energy Expenditure Exercise Fatty Liver Human Lifting Effort Liver Metabolism Parallel Design Physical Activity Physical Education Randomized Controlled Trial Randomized Controlled Trial (Topic) Resistance Training Running Single Blind Procedure Wrestling Enfermedad cardiovascular Obesidad Enfermedades Article Ejercicio físico Trastornos del metabolismo Obesidad Higado graso |
dc.subject.ddc.spa.fl_str_mv |
Enfermedades |
dc.subject.keyword.spa.fl_str_mv |
Article |
dc.subject.lemb.spa.fl_str_mv |
Ejercicio físico Trastornos del metabolismo Obesidad Higado graso |
description |
Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s). |
publishDate |
2018 |
dc.date.created.none.fl_str_mv |
2018 |
dc.date.issued.none.fl_str_mv |
2018 |
dc.date.accessioned.none.fl_str_mv |
2019-09-12T14:39:23Z |
dc.date.available.none.fl_str_mv |
2019-09-12T14:39:23Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
10.1186/s13063-018-2721-5 |
dc.identifier.issn.none.fl_str_mv |
1745-6215 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/20261 |
identifier_str_mv |
10.1186/s13063-018-2721-5 1745-6215 |
url |
https://repository.urosario.edu.co/handle/10336/20261 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationTitle.none.fl_str_mv |
Trials |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 19 |
dc.relation.ispartof.spa.fl_str_mv |
Trials, ISSN:1745-6215, Vol. 19 (2018) |
dc.relation.uri.spa.fl_str_mv |
https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2721-5 |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
institution |
Universidad del Rosario |
dc.source.bibliographicCitation.spa.fl_str_mv |
(2000) Obesity: preventing and managing the global epidemic, , World Health Organization |
dc.source.instname.none.fl_str_mv |
instname:Universidad del Rosario |
dc.source.reponame.none.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
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32244cce-6b52-494c-b446-49796f5844426007913910360075b6b2fa-230d-4c46-b327-97ca28a5215a600d1123b4d-11e1-4338-99f1-023fe485bb27600ed3b31e5-f48c-4d4a-ae43-a2c7741658cf600d2207360-ae5d-4531-bc7a-7e5bc43343b5600cece1138-e11a-4c73-b3fc-fd3280f1cfb16003c17b541-fe37-4c01-9f4b-c64d0fa9c919600d6f25b4b-6535-4bc0-9e9f-63c44ef651f66004d5078f3-69d4-468f-8a78-ee94c7e46a4b600e90a654d-7c8f-428f-a5e6-355ab8d8a15b600102238280560015086108-a0ae-4b67-a146-2f83306369b06005b98ae1d-a547-468c-82ff-b290c97bce7c600945181836002019-09-12T14:39:23Z2019-09-12T14:39:23Z20182018Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s).application/pdf10.1186/s13063-018-2721-51745-6215https://repository.urosario.edu.co/handle/10336/20261engTrialsVol. 19Trials, ISSN:1745-6215, Vol. 19 (2018)https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2721-5Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2(2000) Obesity: preventing and managing the global epidemic, , World Health Organizationinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAdolescentAdolescent ObesityCardiovascular DiseaseColombiaControlled StudyEndurance TrainingEnergy ExpenditureExerciseFatty LiverHumanLifting EffortLiver MetabolismParallel DesignPhysical ActivityPhysical EducationRandomized Controlled TrialRandomized Controlled Trial (Topic)Resistance TrainingRunningSingle Blind ProcedureWrestlingEnfermedad cardiovascularObesidadEnfermedades616600ArticleEjercicio físicoTrastornos del metabolismoObesidadHigado grasoEffects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trialarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501González Ruíz, KatherineCorrea Bautista, Jorge EnriqueIzquierdo, MikelGarcía-Hermoso, AntonioDominguez-Sanchez, María AndreaBustos-Cruz, Rosa HelenaGarcía-Prieto, Jorge CañeteMartínez-Vizcaíno, VicenteLobelo, FelipeGonzález-Jiménez, EmilioPrieto Benavides, Daniel HumbertoTordecilla Sanders, María AlejandraSchmidt-Riovalle, JacquelinePerez, GuillermoRamírez-Vélez, RobinsonGonzález-Ruíz, KatherineCorrea-Bautista, Jorge EnriqueIzquierdo, MikelGarcía-Hermoso, AntonioDominguez-Sanchez, María AndreaBustos-Cruz, Rosa HelenaGarcía-Prieto, Jorge CañeteMartínez-Vizcaíno, VicenteLobelo, FelipeGonzález-Jiménez, EmilioPrieto-Benavides, Daniel HumbertoTordecilla-Sanders, AlejandraSchmidt-RioValle, JacquelinePerez, GuillermoRamírez-Vélez, RobinsonORIGINAL41.pdfapplication/pdf1603835https://repository.urosario.edu.co/bitstreams/3a3f9e42-8633-481d-831f-a3bdd91f4451/download87ce161ff949ff15fb02ca3a7cdfc64bMD51TEXT41.pdf.txt41.pdf.txtExtracted texttext/plain83570https://repository.urosario.edu.co/bitstreams/c736f30c-ea18-4071-b446-0017396d8a65/downloadea50716989603dd99763244b2e7fae5eMD52THUMBNAIL41.pdf.jpg41.pdf.jpgGenerated Thumbnailimage/jpeg3975https://repository.urosario.edu.co/bitstreams/513a0a0e-cbca-47c9-b24c-c81971cfa723/download67d7866d3d2c7b02be0d6978bfa696a1MD5310336/20261oai:repository.urosario.edu.co:10336/202612019-09-19 07:38:03.190837https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |