Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial

Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several h...

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Fecha de publicación:
2018
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/20261
Acceso en línea:
https://repository.urosario.edu.co/handle/10336/20261
Palabra clave:
Adolescent
Adolescent Obesity
Cardiovascular Disease
Colombia
Controlled Study
Endurance Training
Energy Expenditure
Exercise
Fatty Liver
Human
Lifting Effort
Liver Metabolism
Parallel Design
Physical Activity
Physical Education
Randomized Controlled Trial
Randomized Controlled Trial (Topic)
Resistance Training
Running
Single Blind Procedure
Wrestling
Enfermedad cardiovascular
Obesidad
Enfermedades
Article
Ejercicio físico
Trastornos del metabolismo
Obesidad
Higado graso
Rights
License
Abierto (Texto Completo)
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repository_id_str
dc.title.spa.fl_str_mv Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
title Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
spellingShingle Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
Adolescent
Adolescent Obesity
Cardiovascular Disease
Colombia
Controlled Study
Endurance Training
Energy Expenditure
Exercise
Fatty Liver
Human
Lifting Effort
Liver Metabolism
Parallel Design
Physical Activity
Physical Education
Randomized Controlled Trial
Randomized Controlled Trial (Topic)
Resistance Training
Running
Single Blind Procedure
Wrestling
Enfermedad cardiovascular
Obesidad
Enfermedades
Article
Ejercicio físico
Trastornos del metabolismo
Obesidad
Higado graso
title_short Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
title_full Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
title_fullStr Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
title_full_unstemmed Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
title_sort Effects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trial
dc.subject.spa.fl_str_mv Adolescent
Adolescent Obesity
Cardiovascular Disease
Colombia
Controlled Study
Endurance Training
Energy Expenditure
Exercise
Fatty Liver
Human
Lifting Effort
Liver Metabolism
Parallel Design
Physical Activity
Physical Education
Randomized Controlled Trial
Randomized Controlled Trial (Topic)
Resistance Training
Running
Single Blind Procedure
Wrestling
Enfermedad cardiovascular
Obesidad
topic Adolescent
Adolescent Obesity
Cardiovascular Disease
Colombia
Controlled Study
Endurance Training
Energy Expenditure
Exercise
Fatty Liver
Human
Lifting Effort
Liver Metabolism
Parallel Design
Physical Activity
Physical Education
Randomized Controlled Trial
Randomized Controlled Trial (Topic)
Resistance Training
Running
Single Blind Procedure
Wrestling
Enfermedad cardiovascular
Obesidad
Enfermedades
Article
Ejercicio físico
Trastornos del metabolismo
Obesidad
Higado graso
dc.subject.ddc.spa.fl_str_mv Enfermedades
dc.subject.keyword.spa.fl_str_mv Article
dc.subject.lemb.spa.fl_str_mv Ejercicio físico
Trastornos del metabolismo
Obesidad
Higado graso
description Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s).
publishDate 2018
dc.date.created.none.fl_str_mv 2018
dc.date.issued.none.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2019-09-12T14:39:23Z
dc.date.available.none.fl_str_mv 2019-09-12T14:39:23Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv 10.1186/s13063-018-2721-5
dc.identifier.issn.none.fl_str_mv 1745-6215
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/20261
identifier_str_mv 10.1186/s13063-018-2721-5
1745-6215
url https://repository.urosario.edu.co/handle/10336/20261
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationTitle.none.fl_str_mv Trials
dc.relation.citationVolume.none.fl_str_mv Vol. 19
dc.relation.ispartof.spa.fl_str_mv Trials, ISSN:1745-6215, Vol. 19 (2018)
dc.relation.uri.spa.fl_str_mv https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2721-5
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institution Universidad del Rosario
dc.source.bibliographicCitation.spa.fl_str_mv (2000) Obesity: preventing and managing the global epidemic, , World Health Organization
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
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spelling 32244cce-6b52-494c-b446-49796f5844426007913910360075b6b2fa-230d-4c46-b327-97ca28a5215a600d1123b4d-11e1-4338-99f1-023fe485bb27600ed3b31e5-f48c-4d4a-ae43-a2c7741658cf600d2207360-ae5d-4531-bc7a-7e5bc43343b5600cece1138-e11a-4c73-b3fc-fd3280f1cfb16003c17b541-fe37-4c01-9f4b-c64d0fa9c919600d6f25b4b-6535-4bc0-9e9f-63c44ef651f66004d5078f3-69d4-468f-8a78-ee94c7e46a4b600e90a654d-7c8f-428f-a5e6-355ab8d8a15b600102238280560015086108-a0ae-4b67-a146-2f83306369b06005b98ae1d-a547-468c-82ff-b290c97bce7c600945181836002019-09-12T14:39:23Z2019-09-12T14:39:23Z20182018Background: A considerable proportion of contemporary youth have a high risk of obesity-related disorders such as cardiovascular disease, metabolic syndrome, or non-alcoholic fatty liver disease (NAFLD). Although there is consistent evidence for the positive effects of physical activity on several health aspects, most adolescents in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in lifestyle. The HEPAFIT study aims to examine whether a 6-month exercise program has benefits for hepatic fat content and cardiovascular health outcomes among overweight/obese adolescents from Bogotá, Colombia. Methods/design: Altogether, 100 hundred overweight/obese, sedentary adolescents (aged 11-17 years) attending two public schools in Bogotá, Colombia, will be included in a parallel-group randomized controlled trial. Adolescents will be randomly assigned to an intervention group following one of four curricula: (1) the standard physical education curriculum (60 min per week of physical activity, n = 25) at low-to-moderate intensity; (2) a high-intensity physical education curriculum (HIPE, n = 25), consisting of endurance and resistance games and non-competitive activities, such as running, gymkhanas, lifting, pushing, wrestling, or hauling, for 60-min sessions, three times per week, with an energy expenditure goal of 300 to 500 kcal/session at 75-85% maximum heart rate (HRmax); (3) a low-to-moderate intensity physical education curriculum (LIPE, n = 25) consisting of endurance and resistance games and non-competitive activities (e.g., chasing, sprinting, dribbling, or hopping) for 60-min sessions, three times per week with an energy expenditure goal of 300 kcal/session at 55-75% HRmax; and (4) a combined HIPE and LIPE curriculum (n = 25). The HIPE, LIPE, and combined interventions were performed in addition to the standard physical education curriculum. The primary outcome for effectiveness is liver fat content, as measured by the controlled attenuation parameter 1 week after the end of the intervention program. Discussion: The translational focus may be suitable for collecting new information in a school setting on the possible effects of physical activity interventions to reduce liver fat content and to improve metabolic profiles and the cardiometabolic health of overweight/obese adolescents. This may lead to the more efficient use of school physical education resources. © 2018 The Author(s).application/pdf10.1186/s13063-018-2721-51745-6215https://repository.urosario.edu.co/handle/10336/20261engTrialsVol. 19Trials, ISSN:1745-6215, Vol. 19 (2018)https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2721-5Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2(2000) Obesity: preventing and managing the global epidemic, , World Health Organizationinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAdolescentAdolescent ObesityCardiovascular DiseaseColombiaControlled StudyEndurance TrainingEnergy ExpenditureExerciseFatty LiverHumanLifting EffortLiver MetabolismParallel DesignPhysical ActivityPhysical EducationRandomized Controlled TrialRandomized Controlled Trial (Topic)Resistance TrainingRunningSingle Blind ProcedureWrestlingEnfermedad cardiovascularObesidadEnfermedades616600ArticleEjercicio físicoTrastornos del metabolismoObesidadHigado grasoEffects of an exercise program on hepatic metabolism, hepatic fat, and cardiovascular health in overweight/obese adolescents from Bogotá, Colombia (the HEPAFIT study): Study protocol for a randomized controlled trialarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501González Ruíz, KatherineCorrea Bautista, Jorge EnriqueIzquierdo, MikelGarcía-Hermoso, AntonioDominguez-Sanchez, María AndreaBustos-Cruz, Rosa HelenaGarcía-Prieto, Jorge CañeteMartínez-Vizcaíno, VicenteLobelo, FelipeGonzález-Jiménez, EmilioPrieto Benavides, Daniel HumbertoTordecilla Sanders, María AlejandraSchmidt-Riovalle, JacquelinePerez, GuillermoRamírez-Vélez, RobinsonGonzález-Ruíz, KatherineCorrea-Bautista, Jorge EnriqueIzquierdo, MikelGarcía-Hermoso, AntonioDominguez-Sanchez, María AndreaBustos-Cruz, Rosa HelenaGarcía-Prieto, Jorge CañeteMartínez-Vizcaíno, VicenteLobelo, FelipeGonzález-Jiménez, EmilioPrieto-Benavides, Daniel HumbertoTordecilla-Sanders, AlejandraSchmidt-RioValle, JacquelinePerez, GuillermoRamírez-Vélez, RobinsonORIGINAL41.pdfapplication/pdf1603835https://repository.urosario.edu.co/bitstreams/3a3f9e42-8633-481d-831f-a3bdd91f4451/download87ce161ff949ff15fb02ca3a7cdfc64bMD51TEXT41.pdf.txt41.pdf.txtExtracted texttext/plain83570https://repository.urosario.edu.co/bitstreams/c736f30c-ea18-4071-b446-0017396d8a65/downloadea50716989603dd99763244b2e7fae5eMD52THUMBNAIL41.pdf.jpg41.pdf.jpgGenerated Thumbnailimage/jpeg3975https://repository.urosario.edu.co/bitstreams/513a0a0e-cbca-47c9-b24c-c81971cfa723/download67d7866d3d2c7b02be0d6978bfa696a1MD5310336/20261oai:repository.urosario.edu.co:10336/202612019-09-19 07:38:03.190837https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co