Candida albicans resistence mechanisms, tools for its analysis

Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, li...

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Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23940
Acceso en línea:
https://repository.urosario.edu.co/handle/10336/23940
Palabra clave:
Antifungal resistance
Article
Candida albicans
Nonhuman
Proteomics
Candida albicans
Proteomics
Resistance mechanisms
Rights
License
Abierto (Texto Completo)
id EDOCUR2_6759e56092852dc041b85eb0bfc121d0
oai_identifier_str oai:repository.urosario.edu.co:10336/23940
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling d1af445a-4a8f-41d3-8ba9-75641547fe1e-19771199600362a1f75-8b2f-4011-b78b-186ffed774ee-1223fc8fc-8047-4196-803b-428c40b90eb3-13aa9da35-8695-4d11-980e-290250700d2f-16b9b5598-6cea-49e9-be9e-4a78e7c56e31-185cfdf98-214b-4979-91f2-7d4892e1fb2c-12020-05-26T00:06:53Z2020-05-26T00:06:53Z2018Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, live in communities and evade the action of the immune system. This capacity increases its resistance to antimicrobial molecules compared to microorganisms in free or planktonic state. Fluconazole and amphotericin b are the main drugs used against the infection caused by this microorganism; however, resistance to these antifungals and other azoles is a growing problem. In this review, proteomics is highlighted as an alternative tool for the analysis of C. albicans resistance mechanisms. © 2018 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.application/pdf14050994https://repository.urosario.edu.co/handle/10336/23940engComunicaciones Cientificas Mexicanas S.A. de C.V.92No. 386Enfermedades Infecciosas y MicrobiologiaVol. 38Enfermedades Infecciosas y Microbiologia, ISSN:14050994, Vol.38, No.3 (2018); pp. 86-92https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069488242&partnerID=40&md5=d1abb25e69e8465b6524475070698fd7Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAntifungal resistanceArticleCandida albicansNonhumanProteomicsCandida albicansProteomicsResistance mechanismsCandida albicans resistence mechanisms, tools for its analysisHerramientas para el análisis de mecanismos de resistencia de Candida albicansarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Pinilla Bermúdez G.Muñoz Henao, Julián EstebanNavarrete Ospina J.Muñoz Molina L.C.Lindarte Celis D.A.Molano Aponte J.A.Montes Castillo J.M.10336/23940oai:repository.urosario.edu.co:10336/239402022-05-02 07:37:21.289623https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Candida albicans resistence mechanisms, tools for its analysis
dc.title.TranslatedTitle.spa.fl_str_mv Herramientas para el análisis de mecanismos de resistencia de Candida albicans
title Candida albicans resistence mechanisms, tools for its analysis
spellingShingle Candida albicans resistence mechanisms, tools for its analysis
Antifungal resistance
Article
Candida albicans
Nonhuman
Proteomics
Candida albicans
Proteomics
Resistance mechanisms
title_short Candida albicans resistence mechanisms, tools for its analysis
title_full Candida albicans resistence mechanisms, tools for its analysis
title_fullStr Candida albicans resistence mechanisms, tools for its analysis
title_full_unstemmed Candida albicans resistence mechanisms, tools for its analysis
title_sort Candida albicans resistence mechanisms, tools for its analysis
dc.subject.keyword.spa.fl_str_mv Antifungal resistance
Article
Candida albicans
Nonhuman
Proteomics
Candida albicans
Proteomics
Resistance mechanisms
topic Antifungal resistance
Article
Candida albicans
Nonhuman
Proteomics
Candida albicans
Proteomics
Resistance mechanisms
description Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, live in communities and evade the action of the immune system. This capacity increases its resistance to antimicrobial molecules compared to microorganisms in free or planktonic state. Fluconazole and amphotericin b are the main drugs used against the infection caused by this microorganism; however, resistance to these antifungals and other azoles is a growing problem. In this review, proteomics is highlighted as an alternative tool for the analysis of C. albicans resistance mechanisms. © 2018 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.
publishDate 2018
dc.date.created.spa.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2020-05-26T00:06:53Z
dc.date.available.none.fl_str_mv 2020-05-26T00:06:53Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.issn.none.fl_str_mv 14050994
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/23940
identifier_str_mv 14050994
url https://repository.urosario.edu.co/handle/10336/23940
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 92
dc.relation.citationIssue.none.fl_str_mv No. 3
dc.relation.citationStartPage.none.fl_str_mv 86
dc.relation.citationTitle.none.fl_str_mv Enfermedades Infecciosas y Microbiologia
dc.relation.citationVolume.none.fl_str_mv Vol. 38
dc.relation.ispartof.spa.fl_str_mv Enfermedades Infecciosas y Microbiologia, ISSN:14050994, Vol.38, No.3 (2018); pp. 86-92
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069488242&partnerID=40&md5=d1abb25e69e8465b6524475070698fd7
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Comunicaciones Cientificas Mexicanas S.A. de C.V.
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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