Candida albicans resistence mechanisms, tools for its analysis
Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, li...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/23940
- Acceso en línea:
- https://repository.urosario.edu.co/handle/10336/23940
- Palabra clave:
- Antifungal resistance
Article
Candida albicans
Nonhuman
Proteomics
Candida albicans
Proteomics
Resistance mechanisms
- Rights
- License
- Abierto (Texto Completo)
| Summary: | Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, live in communities and evade the action of the immune system. This capacity increases its resistance to antimicrobial molecules compared to microorganisms in free or planktonic state. Fluconazole and amphotericin b are the main drugs used against the infection caused by this microorganism; however, resistance to these antifungals and other azoles is a growing problem. In this review, proteomics is highlighted as an alternative tool for the analysis of C. albicans resistance mechanisms. © 2018 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved. |
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