Synthesis and characterization of porous silicon as hydroxyapatite host matrix of biomedical applications

In this work, porous-silicon samples were prepared by electrochemical etching on p-type (Bdoped) Silicon (Si) wafers. Hydrofluoric acid (HF)-ethanol (C2H5OH) [HF:Et] and Hydrofluoric acid (HF)-dimethylformamide (DMF-C3H7NO) [HF:DMF] solution concentrations were varied between [1:2]-[1:3] and [1:7]-[1:9], respectively. Effects of synthesis parameters, like current density, solution concentrations, reaction time, on morphological properties were studied by scanning electron microscopy (SEM) and atomic force microscopy (AFM) measurements. Pore sizes varying from 20 nm to micrometers were obtained for long reaction times and [HF:Et] [1:2] concentrations; while pore sizes in the same order were observed for [HF:DMF] [1:7], but for shorter reaction time. Greater surface uniformity and pore distribution was obtained for a current density of around 8 mA/cm2 using solutions with DMF. A correlation between reflectance measurements and pore size is presented. The porous-silicon samples were used as substrate for hydroxyapatite growth by sol-gel method. X-ray diffraction (XRD) and SEM were used to characterize the layers grown. It was found that the layer topography obtained on PS samples was characterized by the evidence of Hydroxyapatite in the inter-pore regions and over the surface. © 2017 Dussan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

• Fecha de publicación: 2017
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/18791
• Acceso en línea: https://doi.org/10.1371/journal.pone.0173118; http://repository.urosario.edu.co/handle/10336/18791
• Palabra clave: Alcohol; Ácido fluorhídrico; Electrón; Dimetilformamida; Hidroxiapatita; Exploración; Silicio; Biomaterial; Fuerza atómica microscópica; Ingeniería Biomédica; Análisis químico; Concentración (Parámetros); Electroquímica; Química Física; Parámetros físicos; Porosidad; Tiempo de reacción; Microscopía electrónica de barrido; Síntesis; Difracción de rayos X; Química; Materiales biocompatibles; Mala suerte; Biocompatible Materials; Hydrofluoric Acid; Reaction Time; Hydroxyapatite; Electron; Scanning; Dimethylformamide; Biomaterial; Atomic Force Microscopy; Silicon; Chemical Analysis; Biomedical Engineering; Concentration (Parameters); Electrochemistry; Physical Parameters; PorosityPhysical Chemistry; Synthesis; Scanning Electron; Microscopy; X Ray Diffraction; Durapatite; Chemistry; Alcohol; Microscopia de fuerza atómica; Ciencias médicas
• License: Abierto (Texto Completo)