Long-term effect of intravitreal triamcinolone in the nonproliferative stage of type II idiopathic parafoveal telangiectasia

PURPOSE: To report the visual outcomes and ocular complications of intravitreal triamcinolone acetonide (IVTA) in the treatment of the nonproliferative stage of type II idiopathic parafoveal telangiectasia (IPT). METHODS: Retrospective, multicenter, uncontrolled interventional case series of 19 eyes of 14 consecutive patients with the nonproliferative stage of IPT that had undergone at least one intravitreal injection of 4 mg of triamcinolone acetonide. Demographic, medical, and ocular data were obtained through chart review. The main outcome measures included best-corrected visual acuity at several timepoints of follow up and ocular complications. RESULTS: At baseline the mean logMAR visual acuity was 0.83 ± 0.41 (Snellen 20/135, range 0.3-2). After an average follow-up of 21.2 months (range 6-44 months), the mean logMAR visual acuity remained essentially unchanged from baseline. At 3 months, the logMAR visual acuity was 0.86 ± 0.44 (Snellen 20/145, P = 0.8378), at 6 months 0.86 ± 0.42 (Snellen 20/145, P = 0.8149), at 12 months 0.87 ± 0.46 (Snellen 20/148, P > 0.9999), at 18 months 0.84 ± 0.35 (Snellen 20/138, P = 0.8385), and at the last follow-up 0.82 ± 0.44 (Snellen 20/132, P = 0.9301). Seven eyes were reinjected once. Ten of 19 eyes (53%) developed cataract (3 eyes underwent phacoemulsification and intraocular lens implantation) and 7 of 19 eyes (37%) had an elevated intraocular pressure, none of which required surgical treatment. CONCLUSION: IVTA does not seem to improve visual acuity in most eyes with the nonproliferative stage of IPT. © The Ophthalmic Communications Society, Inc.

• Fecha de publicación: 2008
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/22935
• Acceso en línea: https://doi.org/10.1097/IAE.0b013e31814cf03e; https://repository.urosario.edu.co/handle/10336/22935
• Palabra clave: Triamcinolone; Glucocorticoid; Triamcinolone acetonide; Adult; Aged; Article; Cataract; Cataract extraction; Clinical article; Controlled study; Disease severity; Drug effect; Female; Follow up; Human; Intraocular pressure; Lens implant; Male; Phacoemulsification; Telangiectasia; Treatment outcome; Type 2 idiopathic parafoveal telangiectasia; Visual acuity; Clinical trial; Fluorescence angiography; Injection; Middle aged; Multicenter study; Pathology; Retina blood vessel; Retina disease; Retina fovea; Retrospective study; Telangiectasia; Vitreous body; Aged; Female; Fluorescein angiography; Fovea centralis; Glucocorticoids; Humans; Injections; Male; Middle aged; Retinal diseases; Retinal vessels; Retrospective studies; Telangiectasis; Treatment outcome; Triamcinolone acetonide; Visual acuity; Vitreous body; Juxtafoveolar telangiectasis; Macular edema; Macular telangiectasia; Parafoveal telangiectasis; Perifoveal telangiectasia; Triamcinolone
• License: Abierto (Texto Completo)