Handgrip and knee extension strength as predictors of cancer mortality: A systematic review and meta-analysis
The specific role of different strength measures on mortality risk needs to be clarified to gain a better understanding of the clinical importance of different muscle groups, as well as to inform intervention protocols in relation to reducing early mortality. The aim of the systematic review and met...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/23268
- Acceso en línea:
- https://doi.org/10.1111/sms.13206
https://repository.urosario.edu.co/handle/10336/23268
- Palabra clave:
- Adult
Cancer mortality
Cohort analysis
Controlled study
Female
Hand grip
Human
Juvenile
Knee
Male
Meta analysis
Muscle strength
Outcome assessment
Prospective study
Review
Systematic review
Hand strength
Mortality
Neoplasm
Proportional hazards model
Hand strength
Humans
Neoplasms
Proportional hazards models
Apparently healthy population
Cancer mortality
Fitness
Meta-analysis
Muscular strength
- Rights
- License
- Abierto (Texto Completo)
| Summary: | The specific role of different strength measures on mortality risk needs to be clarified to gain a better understanding of the clinical importance of different muscle groups, as well as to inform intervention protocols in relation to reducing early mortality. The aim of the systematic review and meta-analysis was to determine the relationship between muscular strength and risk of cancer mortality. Eligible cohort studies were those that examined the association between muscular strength, as assessed using validated tests, and cancer mortality in healthy youth and adults. The hazard ratio (HR) estimates obtained were pooled using random effects meta-analysis models. The outcome was cancer mortality assessed using the HR (Cox proportional hazards model). Eleven prospective studies with 1 309 413 participants were included, and 9787 cancer-specific deaths were reported. Overall, greater handgrip (HR = 0.97, 95% CI, 0.92-1.02; P =.055; I2 = 18.9%) and knee extension strength (HR = 0.98, 95% CI, 0.95-1.00; P =.051; I2 = 60.6%) were barely significant associated with reduced risk of cancer mortality. Our study suggests that higher level of muscular strength is not statistically associated with lower risk of cancer mortality. © 2018 John Wiley and Sons A/S. Published by John Wiley and Sons Ltd |
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