A case report of malignant gastrointestinal melanoma of unknown primary origin

One of the unusual characteristics of cutaneous melanoma is its ability to metastasize in the small intestine. It is often diagnosed during autopsies of cutaneous melanoma patients. Metastatic deposits have been found in 50% to 60% of these autopsies, but less than 2% to 4% of patients diagnosed wit...

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Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23034
Acceso en línea:
https://doi.org/10.22516/25007440.260
https://repository.urosario.edu.co/handle/10336/23034
Palabra clave:
Gastrointestinal tract
Melanoma
Metastasis
Unknown primary neoplasms
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spelling ce28b372-8500-4d0a-ba5c-49d0d2a7b4ad-152fec29b-6c57-4803-80d4-80e65a5c00f3-12020-05-25T23:59:23Z2020-05-25T23:59:23Z2019One of the unusual characteristics of cutaneous melanoma is its ability to metastasize in the small intestine. It is often diagnosed during autopsies of cutaneous melanoma patients. Metastatic deposits have been found in 50% to 60% of these autopsies, but less than 2% to 4% of patients diagnosed with melanoma have gastrointestinal metastasis during the course of the disease. Between 4% and 9% of gastrointestinal melanoma cases have unknown primary tumors. Rapid identification and resection of melanoma in the digestive tract could improve the patient survival rate and prevent complications such as intestinal obstructions from occurring. We present a rare clinical case of gastrointestinal melanoma of unknown primary origin. The patient had a clinical picture of nausea, hyporexia, epigastralgia, fatigue, paresthesias in the right dorsal region and had lost nine kilograms in three weeks. An abdominal CT scan showed three predominantly isodense liver lesions in the parenchyma, with some areas of lower density located in segments 2,5,7 and 8 of the liver. These were biopsied. Upper digestive tract endoscopy took biopsy samples of two hyperpigmented lesions in the second portion of the duodenum. Histopathological examination showed malignant melanoma. All typical locations of primary melanoma were excluded during the diagnostic procedure. © 2019 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología.application/pdfhttps://doi.org/10.22516/25007440.2601209957https://repository.urosario.edu.co/handle/10336/23034engAsociacion Colombiana de Gastroenterologia420No. 4416Revista Colombiana de GastroenterologiaVol. 34Revista Colombiana de Gastroenterologia, ISSN:1209957, Vol.34, No.4 (2019); pp. 416-420https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079484308&doi=10.22516%2f25007440.260&partnerID=40&md5=fe702bf0f914b4d042ac12a64c3c7543Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURGastrointestinal tractMelanomaMetastasisUnknown primary neoplasmsA case report of malignant gastrointestinal melanoma of unknown primary originMelanoma maligno gastrointestinal de origen primario desconocido: Reporte de casoarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Sandra Patricia Cifuentes A.Sandra Lorena Santacruz R.ORIGINAL260-Article_Text-4473-1-10-20200831.pdfapplication/pdf906938https://repository.urosario.edu.co/bitstreams/a0af7196-7549-4d0b-8508-f2be777dc81d/download8cd229be3d46b139d4a95c0702f2a9b0MD51TEXT260-Article_Text-4473-1-10-20200831.pdf.txt260-Article_Text-4473-1-10-20200831.pdf.txtExtracted texttext/plain16401https://repository.urosario.edu.co/bitstreams/4b2115b0-7180-4101-8f15-246c1aeeef63/download2297cafa29bc77ef852c9436475b4dffMD52THUMBNAIL260-Article_Text-4473-1-10-20200831.pdf.jpg260-Article_Text-4473-1-10-20200831.pdf.jpgGenerated Thumbnailimage/jpeg3894https://repository.urosario.edu.co/bitstreams/8e7c31f3-b270-4a70-b34f-1e32ab867124/download76f9fa853447cb0bb35e27d2bfb84e98MD5310336/23034oai:repository.urosario.edu.co:10336/230342022-05-02 07:37:20.721242https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv A case report of malignant gastrointestinal melanoma of unknown primary origin
dc.title.TranslatedTitle.spa.fl_str_mv Melanoma maligno gastrointestinal de origen primario desconocido: Reporte de caso
title A case report of malignant gastrointestinal melanoma of unknown primary origin
spellingShingle A case report of malignant gastrointestinal melanoma of unknown primary origin
Gastrointestinal tract
Melanoma
Metastasis
Unknown primary neoplasms
title_short A case report of malignant gastrointestinal melanoma of unknown primary origin
title_full A case report of malignant gastrointestinal melanoma of unknown primary origin
title_fullStr A case report of malignant gastrointestinal melanoma of unknown primary origin
title_full_unstemmed A case report of malignant gastrointestinal melanoma of unknown primary origin
title_sort A case report of malignant gastrointestinal melanoma of unknown primary origin
dc.subject.keyword.spa.fl_str_mv Gastrointestinal tract
Melanoma
Metastasis
Unknown primary neoplasms
topic Gastrointestinal tract
Melanoma
Metastasis
Unknown primary neoplasms
description One of the unusual characteristics of cutaneous melanoma is its ability to metastasize in the small intestine. It is often diagnosed during autopsies of cutaneous melanoma patients. Metastatic deposits have been found in 50% to 60% of these autopsies, but less than 2% to 4% of patients diagnosed with melanoma have gastrointestinal metastasis during the course of the disease. Between 4% and 9% of gastrointestinal melanoma cases have unknown primary tumors. Rapid identification and resection of melanoma in the digestive tract could improve the patient survival rate and prevent complications such as intestinal obstructions from occurring. We present a rare clinical case of gastrointestinal melanoma of unknown primary origin. The patient had a clinical picture of nausea, hyporexia, epigastralgia, fatigue, paresthesias in the right dorsal region and had lost nine kilograms in three weeks. An abdominal CT scan showed three predominantly isodense liver lesions in the parenchyma, with some areas of lower density located in segments 2,5,7 and 8 of the liver. These were biopsied. Upper digestive tract endoscopy took biopsy samples of two hyperpigmented lesions in the second portion of the duodenum. Histopathological examination showed malignant melanoma. All typical locations of primary melanoma were excluded during the diagnostic procedure. © 2019 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología.
publishDate 2019
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dc.date.accessioned.none.fl_str_mv 2020-05-25T23:59:23Z
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dc.type.eng.fl_str_mv article
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url https://doi.org/10.22516/25007440.260
https://repository.urosario.edu.co/handle/10336/23034
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dc.language.iso.spa.fl_str_mv eng
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dc.relation.citationEndPage.none.fl_str_mv 420
dc.relation.citationIssue.none.fl_str_mv No. 4
dc.relation.citationStartPage.none.fl_str_mv 416
dc.relation.citationTitle.none.fl_str_mv Revista Colombiana de Gastroenterologia
dc.relation.citationVolume.none.fl_str_mv Vol. 34
dc.relation.ispartof.spa.fl_str_mv Revista Colombiana de Gastroenterologia, ISSN:1209957, Vol.34, No.4 (2019); pp. 416-420
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dc.publisher.spa.fl_str_mv Asociacion Colombiana de Gastroenterologia
institution Universidad del Rosario
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