Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas
En este trabajo se describen los hallazgos extrapulmonares detectados por imágenes diagnósticas, de una población colombiana con fibrosis quística, atendida en dos centros de salud de Bogotá, Colombia.
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2023
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- spa
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/40772
- Acceso en línea:
- https://doi.org/10.48713/10336_40772
https://repository.urosario.edu.co/handle/10336/40772
- Palabra clave:
- Fibrosis quística
Manifestaciones extrapulmonares
Cystic fibrosis
Extrapulmonary manifestations
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.title.none.fl_str_mv |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
dc.title.TranslatedTitle.none.fl_str_mv |
Prevalence of extrapulmonary findings in patients with cystic fibrosis: identification by diagnostic images |
title |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
spellingShingle |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas Fibrosis quística Manifestaciones extrapulmonares Cystic fibrosis Extrapulmonary manifestations |
title_short |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
title_full |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
title_fullStr |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
title_full_unstemmed |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
title_sort |
Prevalencia de hallazgos extrapulmonares en pacientes con fibrosis quística: identificación por imágenes diagnósticas |
dc.contributor.advisor.none.fl_str_mv |
Pérez Alvarado, María Carolina Pedraza Flechas, Ana María |
dc.subject.none.fl_str_mv |
Fibrosis quística Manifestaciones extrapulmonares |
topic |
Fibrosis quística Manifestaciones extrapulmonares Cystic fibrosis Extrapulmonary manifestations |
dc.subject.keyword.none.fl_str_mv |
Cystic fibrosis Extrapulmonary manifestations |
description |
En este trabajo se describen los hallazgos extrapulmonares detectados por imágenes diagnósticas, de una población colombiana con fibrosis quística, atendida en dos centros de salud de Bogotá, Colombia. |
publishDate |
2023 |
dc.date.accessioned.none.fl_str_mv |
2023-08-25T20:59:03Z |
dc.date.available.none.fl_str_mv |
2023-08-25T20:59:03Z |
dc.date.created.none.fl_str_mv |
2023-06-20 |
dc.type.none.fl_str_mv |
bachelorThesis |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_7a1f |
dc.type.document.none.fl_str_mv |
Trabajo de grado |
dc.type.spa.none.fl_str_mv |
Trabajo de grado |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.48713/10336_40772 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/40772 |
url |
https://doi.org/10.48713/10336_40772 https://repository.urosario.edu.co/handle/10336/40772 |
dc.language.iso.none.fl_str_mv |
spa |
language |
spa |
dc.rights.*.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.none.fl_str_mv |
Abierto (Texto Completo) |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International Abierto (Texto Completo) http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2 |
dc.format.extent.none.fl_str_mv |
55 pp |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidad del Rosario |
dc.publisher.department.none.fl_str_mv |
Escuela de Medicina y Ciencias de la Salud |
dc.publisher.program.none.fl_str_mv |
Especialización en Radiología |
publisher.none.fl_str_mv |
Universidad del Rosario |
institution |
Universidad del Rosario |
dc.source.bibliographicCitation.none.fl_str_mv |
Foundation CF. Patient Registry 2012. Bethesda, MD Cyst Fibros Found [Internet]. 2012 Dec; Available from: http://www.tandfonline.com/doi/abs/10.1080/14608940701737359 Mateus H AP. Tamizaje Neonatal para Fibrosis Quística en una muestra de la ciudad de Bogotá. Univ del Rosario. 2011 Riordan JR, Rommens JM, Kerem BS, Alon NOA, Rozmahel R, Grzelczak Z, et al. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA. Science (80- ). 1989;245(4922):1066–73 Fustik S. Liver cirrhosis and portal hypertension in cystic fibrosis. Srp Arh Celok Lek [Internet]. 2013;141(11–12):764–9. Available from: http://www.doiserbia.nb.rs/Article.aspx?ID=0370-81791312764F Debray D, Kelly D, Houwen R, Strandvik B, Colombo C. Best practice guidance for the diagnosis and management of cystic fibrosis-associated liver disease. J Cyst Fibros [Internet]. 2011 Jun;10(SUPPL. 2):S29–36. Available from: http://dx.doi.org/10.1016/S1569-1993(11)60006-4 Parad RB, Comeau AM, Dorkin HL, Dovey M, Gerstle R, Martin T, et al. Sweat Testing Infants Detected by Cystic Fibrosis Newborn Screening. J Pediatr [Internet]. 2005 Sep;147(3):S69–72. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0022347605007602 Nishioka GJ, Cook PR. Paranasal sinus disease in patients with cystic fibrosis. Otolaryngol Clin North Am. 1996;29(1):193–206 Gergin O, Kawai K, MacDougall RD, Robson CD, Moritz E, Cunningham M, et al. Sinus Computed Tomography Imaging in Pediatric Cystic Fibrosis. Otolaryngol Neck Surg [Internet]. 2016 Jul;155(1):160–5. Available from: http://journals.sagepub.com/doi/10.1177/0194599816634671 Rybacka A, Karmelita-Katulska K. The role of computed tomography in monitoring patients with cystic fibrosis. Polish J Radiol. 2016;81:141–5 De Boeck K, Weren M, Proesmans M, Kerem E. Pancreatitis Among Patients With Cystic Fibrosis: Correlation With Pancreatic Status and Genotype. Pediatrics [Internet]. 2005 Apr 1;115(4):e463–9. Available from: http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2004-1764 Parisi GF, Di Dio G, Franzonello C, Gennaro A, Rotolo N, Lionetti E, et al. Liver Disease in Cystic Fibrosis: an Update. Hepat Mon [Internet]. 2013 Aug 14;13(8):8. Available from: http://hepatmon.com/en/articles/55392.html Agrons GA, Corse WR, Markowitz RI, Suarez ES, Perry DR. Gastrointestinal manifestations of cystic fibrosis: radiologic-pathologic correlation. RadioGraphics [Internet]. 1996 Jul;16(4):871–93. Available from: http://pubs.rsna.org/doi/10.1148/radiographics.16.4.8835977 Lisa P, Mcevoy SH, Gibney RG, Mcmahon CJ, Heffernan EJ. Cystic Fibrosis below the Dia phragm : Abdominal Findings in Adult Patients 1. 1989;(3):1–16 Shulman LP, Elias S. Cystic fibrosis. Clin Perinatol [Internet]. 2001 Jun;28(2):383–93. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0095510805700907 Chin M, Aaron SD, Bell SC. The treatment of the pulmonary and extrapulmonary manifestations of cystic fibrosis. Press Medicale [Internet]. 2017;46(6P2):e139–64. Available from: http://dx.doi.org/10.1016/j.lpm.2016.11.030 Lugo-Olivieri CH, Soyer PA, Fishman EK. Cystic fibrosis: Spectrum of thoracic and abdominal ct findings in the adult patient. Clin Imaging [Internet]. 1998 Sep;22(5):346–54. Available from: https://linkinghub.elsevier.com/retrieve/pii/S089970719800031X Sathe MN, Freeman AJ. Gastrointestinal, Pancreatic, and Hepatobiliary Manifestations of Cystic Fibrosis. Pediatr Clin North Am [Internet]. 2016 Aug;63(4):679–98. Available from: http://dx.doi.org/10.1016/j.pcl.2016.04.008 Alexander BM, Petren EK, Rizvi S, Fink A, Ostrenga J, Sewall A. Cystic Fibrosis Patient Registry Annual Data Report 2014. Cyst Fibros Found Patient Regist [Internet]. 2014; Available from: https://www.cff.org/2014-annual-data-report Vásquez C, Aristizábal R, Daza W. Fibrosis quística en Colombia. Registro Colombiano de Fibrosis Quistica. Primer informe. Rev Neumol Pediatr [Internet]. 2010;5(1):44–50. Available from: http://www.neumologia-pediatrica.cl Naehrig S, Chao C-M, Naehrlich L. Cystic Fibrosis. Dtsch Arztebl Int [Internet]. 2017 Aug 21;114(33–34):564–73. Available from: https://www.aerzteblatt.de/10.3238/arztebl.2017.0564 Gabel ME, Galante GJ, Freedman SD. Gastrointestinal and Hepatobiliary Disease in Cystic Fibrosis. Semin Respir Crit Care Med [Internet]. 2019 Dec 28;40(06):825–41. Available from: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1697591 Dodge JA. Gastrointestinal tract and nutrition in cystic fibrosis: pathophysiology. J R Soc Med. 1986;79(12):27–31. Olveira Fuster G, Olveira C. Nutrición, fibrosis quística y aparato digestivo. Nutr Hosp. 2008;23(SUPPL. 2):71–86. Farrell PM, White TB, Ren CL, Hempstead SE, Accurso F, Derichs N, et al. Diagnosis of Cystic Fibrosis: Consensus Guidelines from the Cystic Fibrosis Foundation. J Pediatr [Internet]. 2017;181:S4-S15.e1. Available from: http://dx.doi.org/10.1016/j.jpeds.2016.09.064 Mishra A, Greaves R, Massie J. The relevance of sweat testing for the diagnosis of cystic fibrosis in the genomic era. Clin Biochem Rev [Internet]. 2005;26(4):135–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16648884%0Ahttp://www.pubmedcentral.nih. gov/articlerender.fcgi?artid=PMC1320177 Rosenstein BJ, Cutting GR. The diagnosis of cystic fibrosis: A consensus statement. J Pediatr [Internet]. 1998 Apr;132(4):589–95. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0022347698703440 Aziz ZA, Davies JC, Alton EW, Wells AU, Geddes DM, Hansell DM. Computed tomography and cystic fibrosis: promises and problems. Thorax [Internet]. 2007 Feb 1;62(2):181–6. Available from: http://thorax.bmj.com/cgi/doi/10.1136/thx.2005.054379 Helbich TH, Heinz-Peer G, Fleischmann D, Wojnarowski C, Wunderbaldinger P, Huber S, et al. Evolution of CT findings in patients with cystic fibrosis. Am J Roentgenol [Internet]. 1999 Jul;173(1):81–8. Available from: http://www.ajronline.org/doi/10.2214/ajr.173.1.10397104 Berrocal T, Pajares MP ZA. Pancreatic Cystosis in Children and Young Adults With Cystic Fibrosis: Sonographic, CT, and MRI Findings. Am J Roentgenol. 2005;184:1305–9. Cahill ME, Parmentier J-M, Van Ruyssevelt C, Pauls CH. Pancreatic cystosis in cystic fibrosis. Abdom Imaging [Internet]. 1997 Mar 4;22(3):313–4. Available from: http://link.springer.com/10.1007/s002619900197 King LJ, Scurr ED, Murugan N, Williams SGJ, Westaby D, Healy JC. Hepatobiliary and Pancreatic Manifestations of Cystic Fibrosis: MR Imaging Appearances. RadioGraphics [Internet]. 2000 May;20(3):767–77. Available from: http://pubs.rsna.org/doi/10.1148/radiographics.20.3.g00ma08767 Soyer P, Spelle L, Pelage J-P, Dufresne A-C, Rondeau Y, Gouhiri M, et al. Cystic Fibrosis in Adolescents and Adults: Fatty Replacement of the Pancreas—CT Evaluation and Functional Correlation. Radiology [Internet]. 1999 Mar;210(3):611–5. Available from: http://pubs.rsna.org/doi/10.1148/radiology.210.3.r99mr08611 Colombo, Carla, Russo, Maria Chiara , Zazzeron, Laura, Romano G. Liver disease in cystic fibrosis. J Pediatr Gastroenterol Nutr. 2006;43:S49–55. Colombo C, Battezzati PM. Liver involvement in cystic fibrosis: primary organ damage or innocent bystander? J Hepatol [Internet]. 2004 Dec;41(6):1041–4. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0168827804004593 Akata D, Akhan O, Özcelik U, Özmen MN, Oguzkurt L, Haliloglu M, et al. Hepatobiliary manifestations of cystic fibrosis in children: correlation of CT and US findings. Eur J Radiol [Internet]. 2002 Jan;41(1):26–33. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0720048X01003679 O’Donnell DH, Ryan R, Hayes B, Fennelly D, Gibney RG. Hepatocellular carcinoma complicating cystic fibrosis related liver disease. J Cyst Fibros [Internet]. 2009 Jul;8(4):288–90. Available from: http://dx.doi.org/10.1016/j.jcf.2009.05.002 van der Doef HPJ, Kokke FTM, van der Ent CK, Houwen RHJ. Intestinal Obstruction Syndromes in Cystic Fibrosis: Meconium Ileus, Distal Intestinal Obstruction Syndrome, and Constipation. Curr Gastroenterol Rep [Internet]. 2011 Jun 8;13(3):265–70. Available from: http://link.springer.com/10.1007/s11894-011-0185-9 Edmondson C, Davies JC. Current and future treatment options for cystic fibrosis lung disease: Latest evidence and clinical implications. Ther Adv Chronic Dis. 2016;7(3):170–83. Birnbaum BA, Wilson SR. State of the Art Appendicitis at the Millennium. Radiology. 2000;215(2):337–48. Coughlin BJP, Michael WL, Izant RJ, Stern RC, Doershuk CF. The Spectrum of Appendiceal Disease in Cystic Fibrosim. J Pediatr Surg. 1990;25(8):835–9. Menten R, Lebecque P, Saint-Martin C, Clapuyt P. Outer diameter of the vermiform appendix: Not a valid sonographic criterion for acute appendicitis in patients with cystic fibrosis. Am J Roentgenol. 2005;184(6):1901–3. Neglia JP, Fitzsimmons SC, Maisonneuve P, Schöni MH, Schöni-Affolter F, Corey M, et al. The risk of cancer among patients with cystic fibrosis. N Engl J Med. 1995;332(8):494–9. Maisonneuve P, FitzSimmons SC, Neglia JP, Campbell PW, Lowenfels AB. Cancer risk in nontransplanted and transplanted cystic fibrosis patients: A 10-year study. J Natl Cancer Inst. 2003;95(5):381–7. Barrio Gómez De Agüero MI, García Hernández G, Gartner S, De La Cruz ÓA, Barroso NC, Montaner AE, et al. Protocol for the diagnosis and follow up of patients with cystic fibrosis. An Pediatr. 2009;71(3):250–64. Lopera MM. Revisión comentada de la legislación colombiana en ética de la investigación en salud. Biomédica. 2017;37:577–89. Congreso de la República. Ley Estatutaria No 1266. 2008;1–17. McBennett, K., MacAskill, C. J., Keshock, E., Mahani, M. G., Mata, J., Towbin, A. J., Sankararaman, S., Drumm, M. L., Yu, X., Ren, C. L., Nasr, S. Z., Kutney, K., & Flask, C. A. (2022). Magnetic resonance imaging of cystic fibrosis: Multi- organ imaging in the age of CFTR modulator therapies. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 21(2), e148–e157. https://doi.org/10.1016/j.jcf.2021.11.006 Babiński D. Obrazy radiologiczne zatok przynosowych u chorych na mukowiscydoze Radiographic findings in paranasal sinuses in cystic fibrosis patients]. Otolaryngol Pol. 2002;56(3):313-8. Polish. PMID: 12162019. González MA, Dadán S. Algunos condicionantes del estado nutricional en pacientes pediátricos con fibrosis quística en Colombia. Tesis de grado, Departamento de Bioquímica y Nutrición, Carrera de Nutrición y Dietética, Pontificia Universidad Javeriana 1999. Perez-Brayfield M. R., Caplan D., Gatti J. M., Smith E. A., Kirsch A. J. Metabolic risk factors for stone formation in patients with cystic fibrosis. Journal of Urology. 2002;167(2 I):480–484. doi: 10.1016/s0022-5347(01)69068-2. Nazareth D., Walshaw M. A review of renal disease in cystic fibrosis. Journal of Cystic Fibrosis. 2013;12(4):309–317. doi: 10.1016/j.jcf.2013.03.005. Ministerio de Salud y Protección Social. Guía de Práctica Clínica para la prevención, diagnóstico, tratamiento y rehabilitación de Fibrosis Quística. Colombia. 2014; Guía No. 38. Parra Z, A., Morales M. , O. L., Almanza G. , M. I., & Cuellar S., M. H. (2020). Mortalidad en fibrosis quística. Análisis retrospectivo de cinco años en institución de alta complejidad. Medellín-colombia. Neumología Pediátrica, 15(4), 491–497. https://doi.org/10.51451/np.v15i4.125 |
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Pérez Alvarado, María Carolina3ddfaf5a-8806-40aa-95dc-21f02c4ed56a-1Pedraza Flechas, Ana María52965050Aldana Mancera, Sergio AndresSuárez Niño, Diana CarolinaEspecialista en RadiologíaMaestríaFull timed9a4337d-2b0e-49b1-9ff5-b07393922d18-1f9ab2147-f96e-4443-8fd6-f4fe6a839a36-12023-08-25T20:59:03Z2023-08-25T20:59:03Z2023-06-20En este trabajo se describen los hallazgos extrapulmonares detectados por imágenes diagnósticas, de una población colombiana con fibrosis quística, atendida en dos centros de salud de Bogotá, Colombia.This paper describes the extrapulmonary findings detected by diagnostic images of a colombian population with cystic fibrosis, treated at two health centers in Bogotá, Colombia.55 ppapplication/pdfhttps://doi.org/10.48713/10336_40772 https://repository.urosario.edu.co/handle/10336/40772spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludEspecialización en RadiologíaAttribution-NonCommercial-NoDerivatives 4.0 InternationalAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos.http://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Foundation CF. Patient Registry 2012. Bethesda, MD Cyst Fibros Found [Internet]. 2012 Dec; Available from: http://www.tandfonline.com/doi/abs/10.1080/14608940701737359Mateus H AP. Tamizaje Neonatal para Fibrosis Quística en una muestra de la ciudad de Bogotá. Univ del Rosario. 2011Riordan JR, Rommens JM, Kerem BS, Alon NOA, Rozmahel R, Grzelczak Z, et al. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA. Science (80- ). 1989;245(4922):1066–73Fustik S. Liver cirrhosis and portal hypertension in cystic fibrosis. Srp Arh Celok Lek [Internet]. 2013;141(11–12):764–9. Available from: http://www.doiserbia.nb.rs/Article.aspx?ID=0370-81791312764FDebray D, Kelly D, Houwen R, Strandvik B, Colombo C. Best practice guidance for the diagnosis and management of cystic fibrosis-associated liver disease. J Cyst Fibros [Internet]. 2011 Jun;10(SUPPL. 2):S29–36. Available from: http://dx.doi.org/10.1016/S1569-1993(11)60006-4Parad RB, Comeau AM, Dorkin HL, Dovey M, Gerstle R, Martin T, et al. Sweat Testing Infants Detected by Cystic Fibrosis Newborn Screening. J Pediatr [Internet]. 2005 Sep;147(3):S69–72. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0022347605007602Nishioka GJ, Cook PR. Paranasal sinus disease in patients with cystic fibrosis. Otolaryngol Clin North Am. 1996;29(1):193–206Gergin O, Kawai K, MacDougall RD, Robson CD, Moritz E, Cunningham M, et al. Sinus Computed Tomography Imaging in Pediatric Cystic Fibrosis. Otolaryngol Neck Surg [Internet]. 2016 Jul;155(1):160–5. Available from: http://journals.sagepub.com/doi/10.1177/0194599816634671Rybacka A, Karmelita-Katulska K. The role of computed tomography in monitoring patients with cystic fibrosis. Polish J Radiol. 2016;81:141–5De Boeck K, Weren M, Proesmans M, Kerem E. Pancreatitis Among Patients With Cystic Fibrosis: Correlation With Pancreatic Status and Genotype. Pediatrics [Internet]. 2005 Apr 1;115(4):e463–9. Available from: http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2004-1764Parisi GF, Di Dio G, Franzonello C, Gennaro A, Rotolo N, Lionetti E, et al. Liver Disease in Cystic Fibrosis: an Update. Hepat Mon [Internet]. 2013 Aug 14;13(8):8. Available from: http://hepatmon.com/en/articles/55392.htmlAgrons GA, Corse WR, Markowitz RI, Suarez ES, Perry DR. Gastrointestinal manifestations of cystic fibrosis: radiologic-pathologic correlation. RadioGraphics [Internet]. 1996 Jul;16(4):871–93. Available from: http://pubs.rsna.org/doi/10.1148/radiographics.16.4.8835977Lisa P, Mcevoy SH, Gibney RG, Mcmahon CJ, Heffernan EJ. Cystic Fibrosis below the Dia phragm : Abdominal Findings in Adult Patients 1. 1989;(3):1–16Shulman LP, Elias S. Cystic fibrosis. Clin Perinatol [Internet]. 2001 Jun;28(2):383–93. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0095510805700907Chin M, Aaron SD, Bell SC. The treatment of the pulmonary and extrapulmonary manifestations of cystic fibrosis. Press Medicale [Internet]. 2017;46(6P2):e139–64. Available from: http://dx.doi.org/10.1016/j.lpm.2016.11.030Lugo-Olivieri CH, Soyer PA, Fishman EK. Cystic fibrosis: Spectrum of thoracic and abdominal ct findings in the adult patient. Clin Imaging [Internet]. 1998 Sep;22(5):346–54. Available from: https://linkinghub.elsevier.com/retrieve/pii/S089970719800031XSathe MN, Freeman AJ. Gastrointestinal, Pancreatic, and Hepatobiliary Manifestations of Cystic Fibrosis. 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