Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy

Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver dise...

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Fecha de publicación:
2018
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/24758
Acceso en línea:
https://doi.org/10.1155/2018/7521986
https://repository.urosario.edu.co/handle/10336/24758
Palabra clave:
Medical and Health Sciences
Clinical Sciences
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dc.title.spa.fl_str_mv Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
title Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
spellingShingle Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
Medical and Health Sciences
Clinical Sciences
title_short Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
title_full Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
title_fullStr Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
title_full_unstemmed Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
title_sort Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
dc.subject.keyword.spa.fl_str_mv Medical and Health Sciences
Clinical Sciences
topic Medical and Health Sciences
Clinical Sciences
description Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.
publishDate 2018
dc.date.created.spa.fl_str_mv 2018-12-09
dc.date.accessioned.none.fl_str_mv 2020-06-11T13:21:10Z
dc.date.available.none.fl_str_mv 2020-06-11T13:21:10Z
dc.type.eng.fl_str_mv article
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dc.type.spa.spa.fl_str_mv Artículo
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dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/24758
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https://repository.urosario.edu.co/handle/10336/24758
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language eng
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dc.relation.citationTitle.none.fl_str_mv Case Reports in Hepatology
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