Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria

Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its...

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Tipo de recurso:
Fecha de publicación:
2003
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/26739
Acceso en línea:
https://doi.org/10.1016/S0300-9084(03)00136-6
https://repository.urosario.edu.co/handle/10336/26739
Palabra clave:
Malaria
Peptides
SERA protein
Structure
Vaccine
Rights
License
Restringido (Acceso a grupos específicos)
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network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 47606275-a2de-4c5b-83a0-91f4068624ca-1e6f90bd2-8cc5-4a2b-ae26-6d77808b3ce6-1b9481eab-6af9-473a-942b-94e05963da46-19e3ba9df-fe89-48fe-9521-cc8f452d56f5-1518908816002020-08-19T14:40:09Z2020-08-19T14:40:09Z2003-07Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides’ secondary structure and their function as immunogen against malaria.application/pdfhttps://doi.org/10.1016/S0300-9084(03)00136-6ISSN: 0300-9084EISSN: 1638-6183https://repository.urosario.edu.co/handle/10336/26739engSociété Française de Biochimie et Biologie Moléculaire (SFBBM)Elsevier657No. 7651BiochimieVol. 85Biochimie, ISSN: 0300-9084;EISSN: 1638-6183, Vol.85, No.7 (2003); pp. 651-657 https://www.sciencedirect.com/science/article/abs/pii/S0300908403001366Restringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecBiochimieinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURMalariaPeptidesSERA proteinStructureVaccinePlasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malariaLos análogos de péptidos de la proteína SERA de Plasmodium falciparum que tienen regiones helicoidales cortas inducen protección contra la malariaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Cubillos, MarciaAlba, Martha PatriciaTrujillo, MaryPatarroyo, Manuel ElkinBermudez, Adriana10336/26739oai:repository.urosario.edu.co:10336/267392021-06-03 00:49:58.733https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
dc.title.TranslatedTitle.spa.fl_str_mv Los análogos de péptidos de la proteína SERA de Plasmodium falciparum que tienen regiones helicoidales cortas inducen protección contra la malaria
title Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
spellingShingle Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
Malaria
Peptides
SERA protein
Structure
Vaccine
title_short Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
title_full Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
title_fullStr Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
title_full_unstemmed Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
title_sort Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
dc.subject.keyword.spa.fl_str_mv Malaria
Peptides
SERA protein
Structure
Vaccine
topic Malaria
Peptides
SERA protein
Structure
Vaccine
description Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did not present protection against the disease in these monkeys. Results showed a relationship between these peptides’ secondary structure and their function as immunogen against malaria.
publishDate 2003
dc.date.created.spa.fl_str_mv 2003-07
dc.date.accessioned.none.fl_str_mv 2020-08-19T14:40:09Z
dc.date.available.none.fl_str_mv 2020-08-19T14:40:09Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/S0300-9084(03)00136-6
dc.identifier.issn.none.fl_str_mv ISSN: 0300-9084
EISSN: 1638-6183
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/26739
url https://doi.org/10.1016/S0300-9084(03)00136-6
https://repository.urosario.edu.co/handle/10336/26739
identifier_str_mv ISSN: 0300-9084
EISSN: 1638-6183
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 657
dc.relation.citationIssue.none.fl_str_mv No. 7
dc.relation.citationStartPage.none.fl_str_mv 651
dc.relation.citationTitle.none.fl_str_mv Biochimie
dc.relation.citationVolume.none.fl_str_mv Vol. 85
dc.relation.ispartof.spa.fl_str_mv Biochimie, ISSN: 0300-9084;EISSN: 1638-6183, Vol.85, No.7 (2003); pp. 651-657
dc.relation.uri.spa.fl_str_mv https://www.sciencedirect.com/science/article/abs/pii/S0300908403001366
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.acceso.spa.fl_str_mv Restringido (Acceso a grupos específicos)
rights_invalid_str_mv Restringido (Acceso a grupos específicos)
http://purl.org/coar/access_right/c_16ec
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Société Française de Biochimie et Biologie Moléculaire (SFBBM)
Elsevier
dc.source.spa.fl_str_mv Biochimie
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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