Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia
A Lateral Flow Assay to detect cryptococcal antigen (CrAg® LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg® LFA was 100%. High concordance (kappa index=1.0) between Crypto...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2017
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/21972
- Acceso en línea:
- https://doi.org/10.1590/S1678-9946201759076
https://repository.urosario.edu.co/handle/10336/21972
- Palabra clave:
- Enfermedades
Article
Human
Cryptococcosis
Cryptococcus
Antigen
Diagnosis
Point-of-care
Lateral Flow Assay
Immunochromatographic assay
Latex agglutination system
- Rights
- License
- Abierto (Texto completo)
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f6526ca4-0523-4cfd-8bbb-b718335fbc78-1a5045316-9236-488c-bbae-a65224bc1461-151bf7264-6293-4a5b-8131-319bf7810ec3-1c17e7749-9fca-4197-88da-13268e1275c8-1224b222f-13ec-401c-a7d2-67921e85e073-11598a9c7-daee-42c6-83bf-7ddb0e350ad6-12020-05-12T08:52:39Z2020-05-12T08:52:39Z20172017A Lateral Flow Assay to detect cryptococcal antigen (CrAg® LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg® LFA was 100%. High concordance (kappa index=1.0) between Cryptococcal Antigen Latex Agglutination System (CALAS®) and CrAg® LFA was observed. CrAg® LFA showed higher analytical sensitivity for detecting low concentrations of cryptococcal antigen. © 2017, Instituto de Medicina Tropical de Sao Paulo. All rights reserved.application/pdfhttps://doi.org/10.1590/S1678-99462017590760036-4665https://repository.urosario.edu.co/handle/10336/21972engRevista do Instituto de Medicina Tropical de Sao PauloVol. 59Revista do Instituto de Medicina Tropical de Sao Paulo, ISSN: 0036-4665 Vol. 59, (2017)http://www.scielo.br/pdf/rimtsp/v59/1678-9946-rimtsp-S1678-9946201759076.pdfAbierto (Texto completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocUREnfermedades616600ArticleHumanCryptococcosisCryptococcusAntigenDiagnosisPoint-of-careLateral Flow AssayImmunochromatographic assayLatex agglutination systemEvaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in ColombiaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Cáceres, Diego H.Zuluaga, AlejandraTabares, Ángela M.Chiller, TomGonzález, ÁngelGómez, Beatriz L.Cáceres, Diego H.Zuluaga, AlejandraTabares, Ángela M.Chiller, TomGonzález, ÁngelGómez, Beatriz L.ORIGINALEvaluation_of_a_Cryptococcal_antigen_lateral_flow_assay_in_serum_and_cerebrospinal_fluid_for_rapid_diagnosis_of_cryptococcosis_in_Colombia.pdfapplication/pdf259640https://repository.urosario.edu.co/bitstreams/d2a7ae04-8801-4ec7-b192-fc2b8c575087/download9dd395a0f182419b2df201144d3bd193MD51TEXTEvaluation_of_a_Cryptococcal_antigen_lateral_flow_assay_in_serum_and_cerebrospinal_fluid_for_rapid_diagnosis_of_cryptococcosis_in_Colombia.pdf.txtEvaluation_of_a_Cryptococcal_antigen_lateral_flow_assay_in_serum_and_cerebrospinal_fluid_for_rapid_diagnosis_of_cryptococcosis_in_Colombia.pdf.txtExtracted texttext/plain11465https://repository.urosario.edu.co/bitstreams/abe163aa-bacf-411b-9689-eba380460d6d/download0cab3859c25fd9ea4ccca59add796b8cMD52THUMBNAILEvaluation_of_a_Cryptococcal_antigen_lateral_flow_assay_in_serum_and_cerebrospinal_fluid_for_rapid_diagnosis_of_cryptococcosis_in_Colombia.pdf.jpgEvaluation_of_a_Cryptococcal_antigen_lateral_flow_assay_in_serum_and_cerebrospinal_fluid_for_rapid_diagnosis_of_cryptococcosis_in_Colombia.pdf.jpgGenerated Thumbnailimage/jpeg4640https://repository.urosario.edu.co/bitstreams/f38dab59-a2f7-4a50-a2b4-14b04a1664ba/download2909c03456e0c27684303ed8fd91fcd0MD5310336/21972oai:repository.urosario.edu.co:10336/219722021-06-03 00:49:22.016https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
title |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
spellingShingle |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia Enfermedades Article Human Cryptococcosis Cryptococcus Antigen Diagnosis Point-of-care Lateral Flow Assay Immunochromatographic assay Latex agglutination system |
title_short |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
title_full |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
title_fullStr |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
title_full_unstemmed |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
title_sort |
Evaluation of a Cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia |
dc.subject.ddc.none.fl_str_mv |
Enfermedades |
topic |
Enfermedades Article Human Cryptococcosis Cryptococcus Antigen Diagnosis Point-of-care Lateral Flow Assay Immunochromatographic assay Latex agglutination system |
dc.subject.keyword.spa.fl_str_mv |
Article Human |
dc.subject.keyword.eng.fl_str_mv |
Cryptococcosis Cryptococcus Antigen Diagnosis |
dc.subject.keyword.none.fl_str_mv |
Point-of-care Lateral Flow Assay Immunochromatographic assay Latex agglutination system |
description |
A Lateral Flow Assay to detect cryptococcal antigen (CrAg® LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg® LFA was 100%. High concordance (kappa index=1.0) between Cryptococcal Antigen Latex Agglutination System (CALAS®) and CrAg® LFA was observed. CrAg® LFA showed higher analytical sensitivity for detecting low concentrations of cryptococcal antigen. © 2017, Instituto de Medicina Tropical de Sao Paulo. All rights reserved. |
publishDate |
2017 |
dc.date.created.spa.fl_str_mv |
2017 |
dc.date.issued.none.fl_str_mv |
2017 |
dc.date.accessioned.none.fl_str_mv |
2020-05-12T08:52:39Z |
dc.date.available.none.fl_str_mv |
2020-05-12T08:52:39Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1590/S1678-9946201759076 |
dc.identifier.issn.none.fl_str_mv |
0036-4665 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/21972 |
url |
https://doi.org/10.1590/S1678-9946201759076 https://repository.urosario.edu.co/handle/10336/21972 |
identifier_str_mv |
0036-4665 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationTitle.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de Sao Paulo |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 59 |
dc.relation.ispartof.spa.fl_str_mv |
Revista do Instituto de Medicina Tropical de Sao Paulo, ISSN: 0036-4665 Vol. 59, (2017) |
dc.relation.uri.spa.fl_str_mv |
http://www.scielo.br/pdf/rimtsp/v59/1678-9946-rimtsp-S1678-9946201759076.pdf |
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http://purl.org/coar/access_right/c_abf2 |
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Abierto (Texto completo) |
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Abierto (Texto completo) http://purl.org/coar/access_right/c_abf2 |
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institution |
Universidad del Rosario |
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reponame:Repositorio Institucional EdocUR |
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