Trombosis venosa cerebral en Fundación Cardio Infantil

Antecedentes: La trombosis venosa cerebral es un subtipo inusual de enfermedad cerebrovascular que puede asociarse a complicaciones de alta morbilidad y mortalidad que puede pasarse por alto. En Colombia existen datos insuficientes sobre las características de la presentación de estos pacientes. Obj...

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Fecha de publicación:
2020
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
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spa
OAI Identifier:
oai:repository.urosario.edu.co:10336/30850
Acceso en línea:
https://doi.org/10.48713/10336_30850
https://repository.urosario.edu.co/handle/10336/30850
Palabra clave:
Trombosis venosa cerebral
Trombofilia
Lupus eritematoso sistémico
Síndrome antifosfolípido
Enfermedades
Cerebral venous thrombosis, thrombophilia, systemic erythematosus lupus, antiphospholipid syndrome, Colombia
Cerebral venous thrombosis
Thrombophilia
Systemic erythematosus lupus
Antiphospholipid syndrome
Rights
License
Abierto (Texto Completo)
id EDOCUR2_44c4d3934890a94741f61f7b1ddfeaea
oai_identifier_str oai:repository.urosario.edu.co:10336/30850
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
dc.title.spa.fl_str_mv Trombosis venosa cerebral en Fundación Cardio Infantil
dc.title.TranslatedTitle.eng.fl_str_mv Cerebral Venous Thrombosis in Fundación Cardio Infantil
title Trombosis venosa cerebral en Fundación Cardio Infantil
spellingShingle Trombosis venosa cerebral en Fundación Cardio Infantil
Trombosis venosa cerebral
Trombofilia
Lupus eritematoso sistémico
Síndrome antifosfolípido
Enfermedades
Cerebral venous thrombosis, thrombophilia, systemic erythematosus lupus, antiphospholipid syndrome, Colombia
Cerebral venous thrombosis
Thrombophilia
Systemic erythematosus lupus
Antiphospholipid syndrome
title_short Trombosis venosa cerebral en Fundación Cardio Infantil
title_full Trombosis venosa cerebral en Fundación Cardio Infantil
title_fullStr Trombosis venosa cerebral en Fundación Cardio Infantil
title_full_unstemmed Trombosis venosa cerebral en Fundación Cardio Infantil
title_sort Trombosis venosa cerebral en Fundación Cardio Infantil
dc.contributor.advisor.none.fl_str_mv Ortiz Salas, Paola Andrea
dc.subject.spa.fl_str_mv Trombosis venosa cerebral
Trombofilia
Lupus eritematoso sistémico
Síndrome antifosfolípido
topic Trombosis venosa cerebral
Trombofilia
Lupus eritematoso sistémico
Síndrome antifosfolípido
Enfermedades
Cerebral venous thrombosis, thrombophilia, systemic erythematosus lupus, antiphospholipid syndrome, Colombia
Cerebral venous thrombosis
Thrombophilia
Systemic erythematosus lupus
Antiphospholipid syndrome
dc.subject.ddc.spa.fl_str_mv Enfermedades
dc.subject.keyword.spa.fl_str_mv Cerebral venous thrombosis, thrombophilia, systemic erythematosus lupus, antiphospholipid syndrome, Colombia
Cerebral venous thrombosis
Thrombophilia
Systemic erythematosus lupus
Antiphospholipid syndrome
description Antecedentes: La trombosis venosa cerebral es un subtipo inusual de enfermedad cerebrovascular que puede asociarse a complicaciones de alta morbilidad y mortalidad que puede pasarse por alto. En Colombia existen datos insuficientes sobre las características de la presentación de estos pacientes. Objetivo: Describir las características clínicas y paraclínica de pacientes con trombosis venosa cerebral en la Fundación Cardio Infantil desde 2016 hasta el primer semestre de 2020. Metodología: Se realizó un estudio observacional descriptivo, tipo serie de casos a partir de la base de datos de ingreso de pacientes registrada en la Fundación Cardioinfantil Instituto de Cardiología entre 2016 y 2020. Se realizó un análisis univariado de todas las variables del estudio se describieron los comportamientos de cada una. Se cruzaron las variables relevantes para describir frecuencias de presentación entre cada una de éstas y presencia de trombosis venosa cerebral y la extensión de esta. Resultados: Se incluyeron 25 pacientes con diagnostico de trombosis de senos venosos con edad promedio de 43 años (RIC=22) con mayoría de pacientes del género masculino. En el 56% de los pacientes se identifico un factor de riesgo protrombótico y en el 20% se identificaron trombofilias adquiridas autoinmunes. Los pacientes diabéticos e hipertensos tuvieron una mayor extensión de la trombosis venosa cerebral Conclusión: La mayoría de los pacientes con trombosis venosa cerebral de la fundación cardioinfantil tienen un factor de riesgo protrombótico siendo las más frecuentes las trombofilias adquiridas autoinmunes. Los pacientes diabéticos e hipertensos tenían mayor extensión de la trombosis venosa cerebral
publishDate 2020
dc.date.created.none.fl_str_mv 2020-12-15
dc.date.accessioned.none.fl_str_mv 2021-02-02T20:21:06Z
dc.date.available.none.fl_str_mv 2021-02-02T20:21:06Z
dc.type.eng.fl_str_mv bachelorThesis
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.document.spa.fl_str_mv Descriptivo observacional retrospectivo
dc.type.spa.spa.fl_str_mv Trabajo de grado
dc.identifier.doi.none.fl_str_mv https://doi.org/10.48713/10336_30850
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/30850
url https://doi.org/10.48713/10336_30850
https://repository.urosario.edu.co/handle/10336/30850
dc.language.iso.spa.fl_str_mv spa
language spa
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad del Rosario
dc.publisher.department.spa.fl_str_mv Escuela de Medicina y Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Especialización en Neurología
institution Universidad del Rosario
dc.source.bibliographicCitation.spa.fl_str_mv Dmytriw AA, Song JSA, Yu E, Poon CS. Cerebral venous thrombosis: state of the art diagnosis and management. Neuroradiology. 2018;60(7):669–85
Mehta A, Danesh J, Kuruvilla D. Cerebral Venous Thrombosis Headache. Curr Pain Headache Rep. 2019;23
Poon CS, Chang JK, Swarnkar A, Johnson MH, Wasenko J. Radiologic diagnosis of cerebral venous thrombosis: Pictorial review. Am J Roentgenol. 2007;189(6 SUPPL.):64–75
Wang X, Sun X, Liu H. Clinical analysis and misdiagnosis of cerebral venous thrombosis. Exp Ther Med. 2012;4(5):923–7
Devasagayam S, Wyatt B, Leyden J, Kleinig T. Cerebral Venous Sinus Thrombosis Incidence is Higher Than Previously Thought: A Retrospective Population-Based Study. Stroke. 2016;47(9):2180–2
Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. Prognosis of Cerebral Vein and Dural Sinus Thrombosis: Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35(3):664–70
Colakoglu S, Duman T, Tüfekci A, Bakar M, Nazliel B, Caglayan HZB, et al. A Multicenter Study of 1144 Patients with Cerebral Venous Thrombosis: The VENOST Study. J Stroke Cerebrovasc Dis [Internet]. 2017;26(8):1848–57. Available from: http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.04.020
Khealani BA, Wasay M, Saadah M, Sultana E, Mustafa S, Khan FS, et al. Cerebral venous thrombosis: A descriptive multicenter study of patients in Pakistan and Middle East. Stroke. 2008;39(10):2707–11
Cantú-Brito C, Ruiz-Sandoval JL, Chiquete E, Arauz A, León-Jiménez C, Murillo-Bonilla LM, et al. Factores de riesgo, causas y pronóstico de los tipos de enfermedad vascular cerebral en México: Estudio RENAMEVASC. Rev Mex Neurocienc. 2011;12(5):224–34
Rebolledo-García D, Dominguez-Moreno R, Gonzalez-Vargas PO. Trombosis venosa cerebral: lo que hay que saber. Med Int Mex [Internet]. 2019;35(4):537–52. Available from: https://doi.org/10.24245/mim.v35i4.2503
Zuluaga MI, Massaro M, Franco CA. Trombosis de senos venosos cerebrales: Epidemiología, características clínicas, imaginología y pronóstico. Biomedica. 2015;35(2):196–203
Amaya González P, Ramírez S, Rodríguez J. Trombosis venosa cerebral, descripción clínica de una serie de casos en adultos de Bogotá-Colombia: a case series from Bogotá. Acta Neurológica Colomb. 2012;28(2):70–5
Quintero Almenárez RA, Palacios Sánchez E, Cifuentes Sánchez ME, Castro Avendario JD. Trombosis de venas y senos venosos cerebrales en el Hospital de San José. Rev Repert Med y Cirugía. 2007;16(1):21–7
Bushnell C, Saposnik G. Evaluation and management of cerebral venous thrombosis. Contin Lifelong Learn Neurol. 2014;20(2):335–51
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Haghighi AB, Edgell RC, Cruz-Flores S, Feen E, Piriyawat P, Vora N, et al. Mortality of cerebral venous-sinus thrombosis in a large national sample. Stroke. 2012;43(1):262–4
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Kalita J, Misra UK, Singh VK, Dubey D. Predictors and outcome of status epilepticus in cerebral venous thrombosis. J Neurol [Internet]. 2019;266(2):417–25. Available from: http://dx.doi.org/10.1007/s00415-018-9145-8
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Canedo-Antelo M, Baleato-González S, Mosqueira AJ, Casas-Martínez J, Oleaga L, Vilanova JC, et al. Radiologic clues to cerebral venous thrombosis. Radiographics. 2019;39(6):1611–28
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De Bruijn SFTM, Budde M, Teunisse S, De Haan RJ, Stam J. Long-term outcome of cognition and functional health after cerebral venous sinus thrombosis. Neurology. 2000;54(8):1687–9
Bugnicourt JM, Guegan-Massardier E, Roussel M, Martinaud O, Canaple S, Triquenot-Bagan A, et al. Cognitive impairment after cerebral venous thrombosis: A two-center study. J Neurol. 2013;260(5):1324–31
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spelling Ortiz Salas, Paola Andrea7c0d6872-7c88-4699-be0f-df08e70bd4fb600Bermúdez Riveros, Cristian CamiloGaviria Carrillo, MarianaEspecialista en NeurologíaFull time97874570-39b6-417e-9a3d-a4f98d8967e660010882775976002021-02-02T20:21:06Z2021-02-02T20:21:06Z2020-12-15Antecedentes: La trombosis venosa cerebral es un subtipo inusual de enfermedad cerebrovascular que puede asociarse a complicaciones de alta morbilidad y mortalidad que puede pasarse por alto. En Colombia existen datos insuficientes sobre las características de la presentación de estos pacientes. Objetivo: Describir las características clínicas y paraclínica de pacientes con trombosis venosa cerebral en la Fundación Cardio Infantil desde 2016 hasta el primer semestre de 2020. Metodología: Se realizó un estudio observacional descriptivo, tipo serie de casos a partir de la base de datos de ingreso de pacientes registrada en la Fundación Cardioinfantil Instituto de Cardiología entre 2016 y 2020. Se realizó un análisis univariado de todas las variables del estudio se describieron los comportamientos de cada una. Se cruzaron las variables relevantes para describir frecuencias de presentación entre cada una de éstas y presencia de trombosis venosa cerebral y la extensión de esta. Resultados: Se incluyeron 25 pacientes con diagnostico de trombosis de senos venosos con edad promedio de 43 años (RIC=22) con mayoría de pacientes del género masculino. En el 56% de los pacientes se identifico un factor de riesgo protrombótico y en el 20% se identificaron trombofilias adquiridas autoinmunes. Los pacientes diabéticos e hipertensos tuvieron una mayor extensión de la trombosis venosa cerebral Conclusión: La mayoría de los pacientes con trombosis venosa cerebral de la fundación cardioinfantil tienen un factor de riesgo protrombótico siendo las más frecuentes las trombofilias adquiridas autoinmunes. Los pacientes diabéticos e hipertensos tenían mayor extensión de la trombosis venosa cerebralBackground: Cerebral venous thrombosis is an unusual type of cerebrovascular disease that may associate with complications with high morbidity and mortality and because of its low frequency of presentation and unspecific symptoms can be overlooked. There are no clear data in Colombia about the characteristics and presentation of these patients and there are few studies that describe it. Methodology: We conducted a case series study, based on the database of admitted patients, registered at Fundación Cardioinfantil-Instituto de Cardiología between 2016 and 2020. A univariate analysis of all the variables was conducted of all the variables of the study, and, using central tendency measures the behavior of each one is described. A bivariate analysis was done to describe the presentation between the variables of comorbidities and the presence of central venous thrombosis and the extension of it. Results: 25 patients with cerebral venous thrombosis diagnosis were included, with a mean age of 43 years (IQR=22) with a majority of male patients. In the 56% of the patients a thrombotic risk factor was identified, and in 20% autoimmune acquired thrombophilias were identified. The presence of arterial hypertension and diabetes were documented in the 40% and 20% respectively and most of them had thrombosis in more than one sinus Conclusion: The majority of patients with cerebral venous thrombosis of the Fundación Cardioinfantil-Instituto de Cardiología have a thrombotic risk factor, the most common were autoimmune acquired thrombophilias were identified. The diabetic and hypertense patients had more extensive cerebral venous thrombosis.application/pdfhttps://doi.org/10.48713/10336_30850 https://repository.urosario.edu.co/handle/10336/30850spaUniversidad del RosarioEscuela de Medicina y Ciencias de la SaludEspecialización en NeurologíaAbierto (Texto Completo)EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma.http://purl.org/coar/access_right/c_abf2Dmytriw AA, Song JSA, Yu E, Poon CS. Cerebral venous thrombosis: state of the art diagnosis and management. Neuroradiology. 2018;60(7):669–85Mehta A, Danesh J, Kuruvilla D. Cerebral Venous Thrombosis Headache. Curr Pain Headache Rep. 2019;23Poon CS, Chang JK, Swarnkar A, Johnson MH, Wasenko J. Radiologic diagnosis of cerebral venous thrombosis: Pictorial review. Am J Roentgenol. 2007;189(6 SUPPL.):64–75Wang X, Sun X, Liu H. Clinical analysis and misdiagnosis of cerebral venous thrombosis. Exp Ther Med. 2012;4(5):923–7Devasagayam S, Wyatt B, Leyden J, Kleinig T. Cerebral Venous Sinus Thrombosis Incidence is Higher Than Previously Thought: A Retrospective Population-Based Study. Stroke. 2016;47(9):2180–2Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. Prognosis of Cerebral Vein and Dural Sinus Thrombosis: Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35(3):664–70Colakoglu S, Duman T, Tüfekci A, Bakar M, Nazliel B, Caglayan HZB, et al. A Multicenter Study of 1144 Patients with Cerebral Venous Thrombosis: The VENOST Study. J Stroke Cerebrovasc Dis [Internet]. 2017;26(8):1848–57. Available from: http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.04.020Khealani BA, Wasay M, Saadah M, Sultana E, Mustafa S, Khan FS, et al. Cerebral venous thrombosis: A descriptive multicenter study of patients in Pakistan and Middle East. Stroke. 2008;39(10):2707–11Cantú-Brito C, Ruiz-Sandoval JL, Chiquete E, Arauz A, León-Jiménez C, Murillo-Bonilla LM, et al. Factores de riesgo, causas y pronóstico de los tipos de enfermedad vascular cerebral en México: Estudio RENAMEVASC. Rev Mex Neurocienc. 2011;12(5):224–34Rebolledo-García D, Dominguez-Moreno R, Gonzalez-Vargas PO. Trombosis venosa cerebral: lo que hay que saber. Med Int Mex [Internet]. 2019;35(4):537–52. Available from: https://doi.org/10.24245/mim.v35i4.2503Zuluaga MI, Massaro M, Franco CA. Trombosis de senos venosos cerebrales: Epidemiología, características clínicas, imaginología y pronóstico. Biomedica. 2015;35(2):196–203Amaya González P, Ramírez S, Rodríguez J. Trombosis venosa cerebral, descripción clínica de una serie de casos en adultos de Bogotá-Colombia: a case series from Bogotá. 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