Do your patients suffer from excessive yawning?

Objective: Yawning has been described in relation to drugs such as serotonin reuptake inhibitors, levodopa, dopamine agonists, MAO B inhibitor, morphine, methadone, buprenorphine, dextromethorphan, benzodiazepine, lidocaine, and flecaine. This is a report of two patients, on long-term escitalopram therapy (more than 8 weeks) with stable dosing, who presented excessive yawning. Escitalopram is widely used in major depressive disorder and generalized anxiety disorder. Method: A clinical description of two cases. Results: Two females (62 and 59 years old, respectively) developed excessive daytime yawning. It was not associated with sedation or a feeling of needing sleep. The dosage was reduced and yawning disappeared some hours later. The patients' depression did not recur. Conclusion: Yawning has been described in relation to different selective serotonin reuptake inhibitors and remitted following their discontinuation; it is interesting that the reported yawning in these two cases disappeared with the reduction of dosage, rather than the interruption of treatment. © 2007 The Authors.

• Fecha de publicación: 2007
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/23574
• Acceso en línea: https://doi.org/10.1111/j.1600-0447.2006.00856.x; https://repository.urosario.edu.co/handle/10336/23574
• Palabra clave: Escitalopram; Serotonin uptake inhibitor; Adult; Article; Case report; Clinical examination; Clinical feature; Daytime somnolence; Depression; Drug dose reduction; Excessive yawning; Female; Human; Long term care; Male; Priority journal; Sedation; Side effect; Treatment outcome; Yawning; Citalopram; Depressive disorder; Female; Humans; Middle aged; Serotonin uptake inhibitors; Yawning; Case reports; Citalopram; Drug effects; Yawning; second-generation; drug; Antidepressive agents; Dose-response relationship
• License: Abierto (Texto Completo)