Changes in selenium levels in epilepsy
Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediat...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2005
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/23128
- Acceso en línea:
- https://repository.urosario.edu.co/handle/10336/23128
- Palabra clave:
- Anticonvulsive agent
Free radical
Glutathione peroxidase
Selenium
Selenoprotein
Valproic acid
Anticonvulsive agent
Protein
Selenium
Selenoprotein
Behavior
Data base
Epilepsy
Human
Medical literature
Medical research
Neural tube defect
Practice guideline
Pregnancy
Protein synthesis
Review
Vitamin supplementation
Bibliographic database
Blood
Degenerative disease
Diet supplementation
Epilepsy
Female
Metabolism
Oxidative stress
Anticonvulsants
Dietary supplements
Epilepsy
Female
Humans
Neurodegenerative diseases
Oxidative stress
Pregnancy
Proteins
Selenium
Selenoproteins
Anticonvulsants
Epilepsy
Evidence-based medicine
Selenium
Trace elements
bibliographic
Databases
- Rights
- License
- Abierto (Texto Completo)
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824d18a4-84c9-48e0-9260-cc5153390024-1211e7a31-977a-481b-befd-522889b0ef9c-1799427726002020-05-25T23:59:54Z2020-05-25T23:59:54Z2005Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediated damage. Selenium is essential for the synthesis of selenoproteins, including glutathione peroxidase. Aims. To review the present state of knowledge about selenium behaviour in people with epilepsy taking antiepileptic drugs and to develop guidelines for the appropriate use of selenium supplements. Development. Databases such as Medline, Embase, Scisearch and Lilacs were consulted to have access to literature. A search in said databases was performed in order to find articles published from January 1966 to August 2004. All articles published in English and Spanish were considered. A manual review of the references present in each produced article was done in order to identify the articles that the electronic search may have not found itself. The title and abstract of the potential articles were analyzed before asking for the complete article. However, articles which seemed ambiguous were completely analyzed later to establish their relevance. Conclusions. There is insufficient evidence to fully evaluate the effect of selenium supplementation. The possible beneficial effects on pregnancy need to be evaluated in further studies. © 2005, Revista de Neurología.application/pdf2100010https://repository.urosario.edu.co/handle/10336/23128eng116No. 2111Revista de NeurologiaVol. 40Revista de Neurologia, ISSN:2100010, Vol.40, No.2 (2005); pp. 111-116https://www.scopus.com/inward/record.uri?eid=2-s2.0-24344471374&partnerID=40&md5=3204694ef4d385275d26f2d55e941541Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAnticonvulsive agentFree radicalGlutathione peroxidaseSeleniumSelenoproteinValproic acidAnticonvulsive agentProteinSeleniumSelenoproteinBehaviorData baseEpilepsyHumanMedical literatureMedical researchNeural tube defectPractice guidelinePregnancyProtein synthesisReviewVitamin supplementationBibliographic databaseBloodDegenerative diseaseDiet supplementationEpilepsyFemaleMetabolismOxidative stressAnticonvulsantsDietary supplementsEpilepsyFemaleHumansNeurodegenerative diseasesOxidative stressPregnancyProteinsSeleniumSelenoproteinsAnticonvulsantsEpilepsyEvidence-based medicineSeleniumTrace elementsbibliographicDatabasesChanges in selenium levels in epilepsyAlteración de la concentración de selenio en la epilepsiaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Gutiérrez-Álvarez A.M.Moreno C.B.González Reyes, Rodrigo Esteban10336/23128oai:repository.urosario.edu.co:10336/231282022-05-02 07:37:20.753941https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co |
dc.title.spa.fl_str_mv |
Changes in selenium levels in epilepsy |
dc.title.TranslatedTitle.spa.fl_str_mv |
Alteración de la concentración de selenio en la epilepsia |
title |
Changes in selenium levels in epilepsy |
spellingShingle |
Changes in selenium levels in epilepsy Anticonvulsive agent Free radical Glutathione peroxidase Selenium Selenoprotein Valproic acid Anticonvulsive agent Protein Selenium Selenoprotein Behavior Data base Epilepsy Human Medical literature Medical research Neural tube defect Practice guideline Pregnancy Protein synthesis Review Vitamin supplementation Bibliographic database Blood Degenerative disease Diet supplementation Epilepsy Female Metabolism Oxidative stress Anticonvulsants Dietary supplements Epilepsy Female Humans Neurodegenerative diseases Oxidative stress Pregnancy Proteins Selenium Selenoproteins Anticonvulsants Epilepsy Evidence-based medicine Selenium Trace elements bibliographic Databases |
title_short |
Changes in selenium levels in epilepsy |
title_full |
Changes in selenium levels in epilepsy |
title_fullStr |
Changes in selenium levels in epilepsy |
title_full_unstemmed |
Changes in selenium levels in epilepsy |
title_sort |
Changes in selenium levels in epilepsy |
dc.subject.keyword.spa.fl_str_mv |
Anticonvulsive agent Free radical Glutathione peroxidase Selenium Selenoprotein Valproic acid Anticonvulsive agent Protein Selenium Selenoprotein Behavior Data base Epilepsy Human Medical literature Medical research Neural tube defect Practice guideline Pregnancy Protein synthesis Review Vitamin supplementation Bibliographic database Blood Degenerative disease Diet supplementation Epilepsy Female Metabolism Oxidative stress Anticonvulsants Dietary supplements Epilepsy Female Humans Neurodegenerative diseases Oxidative stress Pregnancy Proteins Selenium Selenoproteins Anticonvulsants Epilepsy Evidence-based medicine Selenium Trace elements |
topic |
Anticonvulsive agent Free radical Glutathione peroxidase Selenium Selenoprotein Valproic acid Anticonvulsive agent Protein Selenium Selenoprotein Behavior Data base Epilepsy Human Medical literature Medical research Neural tube defect Practice guideline Pregnancy Protein synthesis Review Vitamin supplementation Bibliographic database Blood Degenerative disease Diet supplementation Epilepsy Female Metabolism Oxidative stress Anticonvulsants Dietary supplements Epilepsy Female Humans Neurodegenerative diseases Oxidative stress Pregnancy Proteins Selenium Selenoproteins Anticonvulsants Epilepsy Evidence-based medicine Selenium Trace elements bibliographic Databases |
dc.subject.keyword.eng.fl_str_mv |
bibliographic Databases |
description |
Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediated damage. Selenium is essential for the synthesis of selenoproteins, including glutathione peroxidase. Aims. To review the present state of knowledge about selenium behaviour in people with epilepsy taking antiepileptic drugs and to develop guidelines for the appropriate use of selenium supplements. Development. Databases such as Medline, Embase, Scisearch and Lilacs were consulted to have access to literature. A search in said databases was performed in order to find articles published from January 1966 to August 2004. All articles published in English and Spanish were considered. A manual review of the references present in each produced article was done in order to identify the articles that the electronic search may have not found itself. The title and abstract of the potential articles were analyzed before asking for the complete article. However, articles which seemed ambiguous were completely analyzed later to establish their relevance. Conclusions. There is insufficient evidence to fully evaluate the effect of selenium supplementation. The possible beneficial effects on pregnancy need to be evaluated in further studies. © 2005, Revista de Neurología. |
publishDate |
2005 |
dc.date.created.spa.fl_str_mv |
2005 |
dc.date.accessioned.none.fl_str_mv |
2020-05-25T23:59:54Z |
dc.date.available.none.fl_str_mv |
2020-05-25T23:59:54Z |
dc.type.eng.fl_str_mv |
article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.spa.spa.fl_str_mv |
Artículo |
dc.identifier.issn.none.fl_str_mv |
2100010 |
dc.identifier.uri.none.fl_str_mv |
https://repository.urosario.edu.co/handle/10336/23128 |
identifier_str_mv |
2100010 |
url |
https://repository.urosario.edu.co/handle/10336/23128 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationEndPage.none.fl_str_mv |
116 |
dc.relation.citationIssue.none.fl_str_mv |
No. 2 |
dc.relation.citationStartPage.none.fl_str_mv |
111 |
dc.relation.citationTitle.none.fl_str_mv |
Revista de Neurologia |
dc.relation.citationVolume.none.fl_str_mv |
Vol. 40 |
dc.relation.ispartof.spa.fl_str_mv |
Revista de Neurologia, ISSN:2100010, Vol.40, No.2 (2005); pp. 111-116 |
dc.relation.uri.spa.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-24344471374&partnerID=40&md5=3204694ef4d385275d26f2d55e941541 |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.acceso.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
institution |
Universidad del Rosario |
dc.source.instname.spa.fl_str_mv |
instname:Universidad del Rosario |
dc.source.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional EdocUR |
repository.name.fl_str_mv |
Repositorio institucional EdocUR |
repository.mail.fl_str_mv |
edocur@urosario.edu.co |
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1814167740008628224 |