Changes in selenium levels in epilepsy

Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediat...

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Tipo de recurso:
Fecha de publicación:
2005
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23128
Acceso en línea:
https://repository.urosario.edu.co/handle/10336/23128
Palabra clave:
Anticonvulsive agent
Free radical
Glutathione peroxidase
Selenium
Selenoprotein
Valproic acid
Anticonvulsive agent
Protein
Selenium
Selenoprotein
Behavior
Data base
Epilepsy
Human
Medical literature
Medical research
Neural tube defect
Practice guideline
Pregnancy
Protein synthesis
Review
Vitamin supplementation
Bibliographic database
Blood
Degenerative disease
Diet supplementation
Epilepsy
Female
Metabolism
Oxidative stress
Anticonvulsants
Dietary supplements
Epilepsy
Female
Humans
Neurodegenerative diseases
Oxidative stress
Pregnancy
Proteins
Selenium
Selenoproteins
Anticonvulsants
Epilepsy
Evidence-based medicine
Selenium
Trace elements
bibliographic
Databases
Rights
License
Abierto (Texto Completo)
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network_acronym_str EDOCUR2
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spelling 824d18a4-84c9-48e0-9260-cc5153390024-1211e7a31-977a-481b-befd-522889b0ef9c-1799427726002020-05-25T23:59:54Z2020-05-25T23:59:54Z2005Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediated damage. Selenium is essential for the synthesis of selenoproteins, including glutathione peroxidase. Aims. To review the present state of knowledge about selenium behaviour in people with epilepsy taking antiepileptic drugs and to develop guidelines for the appropriate use of selenium supplements. Development. Databases such as Medline, Embase, Scisearch and Lilacs were consulted to have access to literature. A search in said databases was performed in order to find articles published from January 1966 to August 2004. All articles published in English and Spanish were considered. A manual review of the references present in each produced article was done in order to identify the articles that the electronic search may have not found itself. The title and abstract of the potential articles were analyzed before asking for the complete article. However, articles which seemed ambiguous were completely analyzed later to establish their relevance. Conclusions. There is insufficient evidence to fully evaluate the effect of selenium supplementation. The possible beneficial effects on pregnancy need to be evaluated in further studies. © 2005, Revista de Neurología.application/pdf2100010https://repository.urosario.edu.co/handle/10336/23128eng116No. 2111Revista de NeurologiaVol. 40Revista de Neurologia, ISSN:2100010, Vol.40, No.2 (2005); pp. 111-116https://www.scopus.com/inward/record.uri?eid=2-s2.0-24344471374&partnerID=40&md5=3204694ef4d385275d26f2d55e941541Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURAnticonvulsive agentFree radicalGlutathione peroxidaseSeleniumSelenoproteinValproic acidAnticonvulsive agentProteinSeleniumSelenoproteinBehaviorData baseEpilepsyHumanMedical literatureMedical researchNeural tube defectPractice guidelinePregnancyProtein synthesisReviewVitamin supplementationBibliographic databaseBloodDegenerative diseaseDiet supplementationEpilepsyFemaleMetabolismOxidative stressAnticonvulsantsDietary supplementsEpilepsyFemaleHumansNeurodegenerative diseasesOxidative stressPregnancyProteinsSeleniumSelenoproteinsAnticonvulsantsEpilepsyEvidence-based medicineSeleniumTrace elementsbibliographicDatabasesChanges in selenium levels in epilepsyAlteración de la concentración de selenio en la epilepsiaarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Gutiérrez-Álvarez A.M.Moreno C.B.González Reyes, Rodrigo Esteban10336/23128oai:repository.urosario.edu.co:10336/231282022-05-02 07:37:20.753941https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Changes in selenium levels in epilepsy
dc.title.TranslatedTitle.spa.fl_str_mv Alteración de la concentración de selenio en la epilepsia
title Changes in selenium levels in epilepsy
spellingShingle Changes in selenium levels in epilepsy
Anticonvulsive agent
Free radical
Glutathione peroxidase
Selenium
Selenoprotein
Valproic acid
Anticonvulsive agent
Protein
Selenium
Selenoprotein
Behavior
Data base
Epilepsy
Human
Medical literature
Medical research
Neural tube defect
Practice guideline
Pregnancy
Protein synthesis
Review
Vitamin supplementation
Bibliographic database
Blood
Degenerative disease
Diet supplementation
Epilepsy
Female
Metabolism
Oxidative stress
Anticonvulsants
Dietary supplements
Epilepsy
Female
Humans
Neurodegenerative diseases
Oxidative stress
Pregnancy
Proteins
Selenium
Selenoproteins
Anticonvulsants
Epilepsy
Evidence-based medicine
Selenium
Trace elements
bibliographic
Databases
title_short Changes in selenium levels in epilepsy
title_full Changes in selenium levels in epilepsy
title_fullStr Changes in selenium levels in epilepsy
title_full_unstemmed Changes in selenium levels in epilepsy
title_sort Changes in selenium levels in epilepsy
dc.subject.keyword.spa.fl_str_mv Anticonvulsive agent
Free radical
Glutathione peroxidase
Selenium
Selenoprotein
Valproic acid
Anticonvulsive agent
Protein
Selenium
Selenoprotein
Behavior
Data base
Epilepsy
Human
Medical literature
Medical research
Neural tube defect
Practice guideline
Pregnancy
Protein synthesis
Review
Vitamin supplementation
Bibliographic database
Blood
Degenerative disease
Diet supplementation
Epilepsy
Female
Metabolism
Oxidative stress
Anticonvulsants
Dietary supplements
Epilepsy
Female
Humans
Neurodegenerative diseases
Oxidative stress
Pregnancy
Proteins
Selenium
Selenoproteins
Anticonvulsants
Epilepsy
Evidence-based medicine
Selenium
Trace elements
topic Anticonvulsive agent
Free radical
Glutathione peroxidase
Selenium
Selenoprotein
Valproic acid
Anticonvulsive agent
Protein
Selenium
Selenoprotein
Behavior
Data base
Epilepsy
Human
Medical literature
Medical research
Neural tube defect
Practice guideline
Pregnancy
Protein synthesis
Review
Vitamin supplementation
Bibliographic database
Blood
Degenerative disease
Diet supplementation
Epilepsy
Female
Metabolism
Oxidative stress
Anticonvulsants
Dietary supplements
Epilepsy
Female
Humans
Neurodegenerative diseases
Oxidative stress
Pregnancy
Proteins
Selenium
Selenoproteins
Anticonvulsants
Epilepsy
Evidence-based medicine
Selenium
Trace elements
bibliographic
Databases
dc.subject.keyword.eng.fl_str_mv bibliographic
Databases
description Introduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediated damage. Selenium is essential for the synthesis of selenoproteins, including glutathione peroxidase. Aims. To review the present state of knowledge about selenium behaviour in people with epilepsy taking antiepileptic drugs and to develop guidelines for the appropriate use of selenium supplements. Development. Databases such as Medline, Embase, Scisearch and Lilacs were consulted to have access to literature. A search in said databases was performed in order to find articles published from January 1966 to August 2004. All articles published in English and Spanish were considered. A manual review of the references present in each produced article was done in order to identify the articles that the electronic search may have not found itself. The title and abstract of the potential articles were analyzed before asking for the complete article. However, articles which seemed ambiguous were completely analyzed later to establish their relevance. Conclusions. There is insufficient evidence to fully evaluate the effect of selenium supplementation. The possible beneficial effects on pregnancy need to be evaluated in further studies. © 2005, Revista de Neurología.
publishDate 2005
dc.date.created.spa.fl_str_mv 2005
dc.date.accessioned.none.fl_str_mv 2020-05-25T23:59:54Z
dc.date.available.none.fl_str_mv 2020-05-25T23:59:54Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.issn.none.fl_str_mv 2100010
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/23128
identifier_str_mv 2100010
url https://repository.urosario.edu.co/handle/10336/23128
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 116
dc.relation.citationIssue.none.fl_str_mv No. 2
dc.relation.citationStartPage.none.fl_str_mv 111
dc.relation.citationTitle.none.fl_str_mv Revista de Neurologia
dc.relation.citationVolume.none.fl_str_mv Vol. 40
dc.relation.ispartof.spa.fl_str_mv Revista de Neurologia, ISSN:2100010, Vol.40, No.2 (2005); pp. 111-116
dc.relation.uri.spa.fl_str_mv https://www.scopus.com/inward/record.uri?eid=2-s2.0-24344471374&partnerID=40&md5=3204694ef4d385275d26f2d55e941541
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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