Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein

Plasmodium vivax remains the most widespread Plasmodium parasite specie around the world, producing about 75 million malaria cases, mainly in South America and Asia. A vaccine against this disease is of urgent need, making the identification of new antigens involved in target cell invasion, and thus...

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Autores:
Tipo de recurso:
Fecha de publicación:
2006
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/25940
Acceso en línea:
https://doi.org/10.1016/j.bbrc.2006.10.082
https://repository.urosario.edu.co/handle/10336/25940
Palabra clave:
Malaria
Plasmodium vivax
Merozoite
MSP7
Vaccine candidate
Rights
License
Restringido (Acceso a grupos específicos)
id EDOCUR2_385942b6b5f4d9e9b4d66d634b7a6e40
oai_identifier_str oai:repository.urosario.edu.co:10336/25940
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling 914e954b-fc69-43d1-8b0b-ddda45ad991a-1fd8d3f6a-56dc-44b0-b3d0-ccd34b8d828f-1a9841cbf-774a-4636-afd9-5b8d49f2e812-1bc380284-d23e-4afd-ad07-efa220c5bd4b-179653065-12020-08-06T16:20:16Z2020-08-06T16:20:16Z2006-12-22Plasmodium vivax remains the most widespread Plasmodium parasite specie around the world, producing about 75 million malaria cases, mainly in South America and Asia. A vaccine against this disease is of urgent need, making the identification of new antigens involved in target cell invasion, and thus potential vaccine candidates, a priority. A protein belonging to the P. vivax merozoite surface protein 7 (PvMSP7) family was identified in this study. This protein (named PvMSP71) has 311 amino acids displaying an N-terminal region sharing high identity with P. falciparum MSP7, as well as a similar proteolytical cleavage pattern. This protein’s expression in P. vivax asexual blood stages was revealed by immuno-histochemical and molecular techniques.application/pdfhttps://doi.org/10.1016/j.bbrc.2006.10.082ISSN: 0006-291XEISSN: 1090-2104https://repository.urosario.edu.co/handle/10336/25940engElsevier644No. 3639Biochemical and Biophysical Research CommunicationsVol. 351Biochemical and Biophysical Research Communications, ISSN: 0006-291X;EISSN: 1090-2104, Vol.351, No.3 (2006); pp.639-644https://www.sciencedirect.com/science/article/abs/pii/S0006291X0602328XRestringido (Acceso a grupos específicos)http://purl.org/coar/access_right/c_16ecBiochemical and Biophysical Research Communicationsinstname:Universidad del Rosarioreponame:Repositorio Institucional EdocURMalariaPlasmodium vivaxMerozoiteMSP7Vaccine candidateCloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface proteinClonación, expresión y caracterización de una proteína de superficie de merozoito de la familia Plasmodium vivax MSP7articleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Mongui, AlvaroPerez-Leal, OscarSoto, Sara C.Cortes, JimenaPatarroyo, Manuel A.10336/25940oai:repository.urosario.edu.co:10336/259402021-06-03 00:50:21.444https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
dc.title.TranslatedTitle.spa.fl_str_mv Clonación, expresión y caracterización de una proteína de superficie de merozoito de la familia Plasmodium vivax MSP7
title Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
spellingShingle Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
Malaria
Plasmodium vivax
Merozoite
MSP7
Vaccine candidate
title_short Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
title_full Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
title_fullStr Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
title_full_unstemmed Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
title_sort Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein
dc.subject.keyword.spa.fl_str_mv Malaria
Plasmodium vivax
Merozoite
MSP7
Vaccine candidate
topic Malaria
Plasmodium vivax
Merozoite
MSP7
Vaccine candidate
description Plasmodium vivax remains the most widespread Plasmodium parasite specie around the world, producing about 75 million malaria cases, mainly in South America and Asia. A vaccine against this disease is of urgent need, making the identification of new antigens involved in target cell invasion, and thus potential vaccine candidates, a priority. A protein belonging to the P. vivax merozoite surface protein 7 (PvMSP7) family was identified in this study. This protein (named PvMSP71) has 311 amino acids displaying an N-terminal region sharing high identity with P. falciparum MSP7, as well as a similar proteolytical cleavage pattern. This protein’s expression in P. vivax asexual blood stages was revealed by immuno-histochemical and molecular techniques.
publishDate 2006
dc.date.created.spa.fl_str_mv 2006-12-22
dc.date.accessioned.none.fl_str_mv 2020-08-06T16:20:16Z
dc.date.available.none.fl_str_mv 2020-08-06T16:20:16Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.bbrc.2006.10.082
dc.identifier.issn.none.fl_str_mv ISSN: 0006-291X
EISSN: 1090-2104
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/25940
url https://doi.org/10.1016/j.bbrc.2006.10.082
https://repository.urosario.edu.co/handle/10336/25940
identifier_str_mv ISSN: 0006-291X
EISSN: 1090-2104
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationEndPage.none.fl_str_mv 644
dc.relation.citationIssue.none.fl_str_mv No. 3
dc.relation.citationStartPage.none.fl_str_mv 639
dc.relation.citationTitle.none.fl_str_mv Biochemical and Biophysical Research Communications
dc.relation.citationVolume.none.fl_str_mv Vol. 351
dc.relation.ispartof.spa.fl_str_mv Biochemical and Biophysical Research Communications, ISSN: 0006-291X;EISSN: 1090-2104, Vol.351, No.3 (2006); pp.639-644
dc.relation.uri.spa.fl_str_mv https://www.sciencedirect.com/science/article/abs/pii/S0006291X0602328X
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.rights.acceso.spa.fl_str_mv Restringido (Acceso a grupos específicos)
rights_invalid_str_mv Restringido (Acceso a grupos específicos)
http://purl.org/coar/access_right/c_16ec
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Elsevier
dc.source.spa.fl_str_mv Biochemical and Biophysical Research Communications
institution Universidad del Rosario
dc.source.instname.none.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.none.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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