Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis

Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural similarities, they have rarely been analyzed as a group. These compounds generate...

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Autores:
Tipo de recurso:
Fecha de publicación:
2012
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/25021
Acceso en línea:
https://doi.org/10.1155/2012/604187
https://repository.urosario.edu.co/handle/10336/25021
Palabra clave:
Medical and Health Sciences
Immunology
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Abierto (Texto Completo)
id EDOCUR2_384a0c35eac57e600ce32db8a54aebe8
oai_identifier_str oai:repository.urosario.edu.co:10336/25021
network_acronym_str EDOCUR2
network_name_str Repositorio EdocUR - U. Rosario
repository_id_str
spelling b2e05cf3-14e6-432f-955e-9b6af8a5a2a1-19a6d058a-1989-4a1f-b7d6-b6bcecdf4ed8-12020-06-11T13:22:06Z2020-06-11T13:22:06Z2012-10-18Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural similarities, they have rarely been analyzed as a group. These compounds generate significant biological alterations that include immune hyperactivation, production of the reactive species of oxygen and tissue injury. These pathological processes may trigger autoimmune responses and lead to the development of rheumatoid arthritis. Populations at risk include those that constantly work in industrial process, mining, and agriculture as well as those that undergo silicone implants. Herein a review on the main features of these compounds and how they may induce autoimmune responses is presented.application/pdfhttps://doi.org/10.1155/2012/6041872090198420901992https://repository.urosario.edu.co/handle/10336/25021engArthritis604187ArthritisVol. 2012Arthritis, ISSN: 20901984, 20901992, Vol.2012, No. (2012-10-18); pp. 604187http://downloads.hindawi.com/journals/arthritis/2012/604187.pdfAbierto (Texto Completo)http://purl.org/coar/access_right/c_abf2instname:Universidad del Rosarioreponame:Repositorio Institucional EdocURMedical and Health SciencesImmunologySilicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid ArthritisarticleArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Speck-Hernandez, Cesar A.Montoya-Ortiz, Gladis10336/25021oai:repository.urosario.edu.co:10336/250212021-06-03 00:50:52.523https://repository.urosario.edu.coRepositorio institucional EdocURedocur@urosario.edu.co
dc.title.spa.fl_str_mv Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
title Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
spellingShingle Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
Medical and Health Sciences
Immunology
title_short Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
title_full Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
title_fullStr Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
title_full_unstemmed Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
title_sort Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis
dc.subject.keyword.spa.fl_str_mv Medical and Health Sciences
Immunology
topic Medical and Health Sciences
Immunology
description Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom. Despite these, structural similarities, they have rarely been analyzed as a group. These compounds generate significant biological alterations that include immune hyperactivation, production of the reactive species of oxygen and tissue injury. These pathological processes may trigger autoimmune responses and lead to the development of rheumatoid arthritis. Populations at risk include those that constantly work in industrial process, mining, and agriculture as well as those that undergo silicone implants. Herein a review on the main features of these compounds and how they may induce autoimmune responses is presented.
publishDate 2012
dc.date.created.spa.fl_str_mv 2012-10-18
dc.date.accessioned.none.fl_str_mv 2020-06-11T13:22:06Z
dc.date.available.none.fl_str_mv 2020-06-11T13:22:06Z
dc.type.eng.fl_str_mv article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.spa.spa.fl_str_mv Artículo
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1155/2012/604187
dc.identifier.issn.none.fl_str_mv 20901984
20901992
dc.identifier.uri.none.fl_str_mv https://repository.urosario.edu.co/handle/10336/25021
url https://doi.org/10.1155/2012/604187
https://repository.urosario.edu.co/handle/10336/25021
identifier_str_mv 20901984
20901992
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.citationStartPage.none.fl_str_mv 604187
dc.relation.citationTitle.none.fl_str_mv Arthritis
dc.relation.citationVolume.none.fl_str_mv Vol. 2012
dc.relation.ispartof.spa.fl_str_mv Arthritis, ISSN: 20901984, 20901992, Vol.2012, No. (2012-10-18); pp. 604187
dc.relation.uri.spa.fl_str_mv http://downloads.hindawi.com/journals/arthritis/2012/604187.pdf
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.acceso.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Arthritis
institution Universidad del Rosario
dc.source.instname.spa.fl_str_mv instname:Universidad del Rosario
dc.source.reponame.spa.fl_str_mv reponame:Repositorio Institucional EdocUR
repository.name.fl_str_mv Repositorio institucional EdocUR
repository.mail.fl_str_mv edocur@urosario.edu.co
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