Ideal cardiovascular health predicts lower risk of abnormal liver enzymes levels in the Chilean National Health Survey (2009–2010)

High levels of gamma glutamyltransferase (gamma-GT) and alanine aminotransferase (ALT), as well as fatty liver index (FLI) has been associated with higher cardiovascular disease risk factors in adults. The aim of this study was to examine the relationship between gamma-GT, ALT, and fatty liver index FLI levels across a gradient number of ideal cardiovascular health metrics in a representative sample of adults from the Chilean National Health Survey 2009–2010. Data from 1,023 men and 1,449 women (? 15 years) from the Chilean Health Survey 2009–2010 were analyzed. Ideal cardiovascular health was defined as meeting ideal levels of the following components: four behaviours (smoking, body mass index, physical activity and diet adherence) and three factors (total cholesterol, blood pressure and fasting glucose). Adults were grouped into three categories according to their number of ideal cardiovascular health metrics: ideal (5–7 metrics), intermediate (3–4 metrics), and poor (0–2 metrics). Blood levels of gamma-GT and ALT were measured and the FLI was calculated. A higher number of ideal cardiovascular health index metric was associated with lower gamma-GT, ALT and FLI (p from trend analysis less than 0.001). Also, adults meeting at least 3–4 metrics were predicted less likely to have prevalence of abnormal levels of gamma-GT and FLI (p less than 0.001) compared to adults who met only 0–2 metrics. These findings reinforce the usefulness of the ideal cardiovascular health metrics proposed by the American Heart Association as a tool to identify target subjects and promote cardiovascular health in South-American adults. © 2017 García-Hermoso et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

• Fecha de publicación: 2017
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/22826
• Acceso en línea: https://doi.org/10.1371/journal.pone.0185908; https://repository.urosario.edu.co/handle/10336/22826
• Palabra clave: Alanine aminotransferase; Gamma glutamyltransferase; Glucose; Alanine aminotransferase; Gamma glutamyltransferase; Alanine aminotransferase blood level; Blood pressure; Body mass; Cardiovascular risk; Controlled study; Digestive system disease assessment; Enzyme liver level; Fatty liver index; Gamma glutamyl transferase blood level; Health behavior; Health survey; Liver level; Medication compliance; Physical activity; Prevalence; Smoking; Aged; Blood; Cardiovascular system; Enzymology; Liver; Middle aged; Risk factor; Alanine transaminase; Cardiovascular system; Gamma-glutamyltransferase; Humans; Middle aged; Risk factors
• License: Abierto (Texto Completo)