Autoimmunity in Guillain-Barré syndrome associated with Zika virus infection and beyond

Autoimmune diseases share common immunopathogenic mechanisms (i.e., the autoimmune tautology), which explain the clinical similarities among them as well as their familial clustering. Guillain-Barré syndrome (GBS), an autoimmune peripheral neuropathy, has been recently associated with Zika virus (ZIKV) infection. Based on a series of cases, this review article provides a comparative analysis of GBS associated with ZIKV infection, contrasted with the general characteristics of GBS in light of the autoimmune tautology, including gender differences in prevalence, subphenotypes, polyautoimmunity, familial autoimmunity, age at onset, pathophysiology, ecology, genetics, ancestry, and treatment. © 2017 Elsevier B.V.

• Fecha de publicación: 2017
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/23278
• Acceso en línea: https://doi.org/10.1016/j.autrev.2017.02.002; https://repository.urosario.edu.co/handle/10336/23278
• Palabra clave: Autoantibody; Ganglioside gm1; Age distribution; Autoimmune thyroiditis; Autoimmunity; Descriptive research; Disease association; Dysautonomia; Guillain barre syndrome; Human; Retrospective study; Review; Rheumatoid arthritis; Sex difference; Systematic review; Systemic lupus erythematosus; Zika fever; Autoimmunity; Complication; Genetics; Guillain-barre syndrome; Zika fever; Autoimmunity; Guillain-barre syndrome; Humans; Retrospective studies; Zika virus infection; Autoimmune tautology; Colombia; Mycoplasma pneumoniae; Polyautoimmunity; Witebsky's postulates
• License: Abierto (Texto Completo)