Ideal Cardiovascular Health and Incident Cardiovascular Disease Among Adults: A Systematic Review and Meta-analysis

Objective: To investigate the association between ideal cardiovascular health (CVH) metrics and incident cardiovascular disease (CVD) by conducting a systematic review and meta-analysis of prospective cohort studies. Methods: The MEDLINE, EMBASE, and CINAHL databases were searched from January 1, 2010, through July 31, 2017, for studies that met the following criteria: (1) prospective studies conducted in adults, (2) with outcome data on CVD incidence and (3) a measure of ideal CVH metrics. Results: Twelve studies (210,443 adults) were included in this analysis. Compared with adults who met 0 to 2 of the ideal CVH metrics (high-risk individuals), a significantly lower hazard for CVD incidence was observed in those who had 3 to 4 points for the ideal CVH metrics (hazard ratio [HR]=0.53; 95% CI, 0.47-0.59) and 5 to 7 points (HR=0.28; 95% CI, 0.23-0.33). Weaker associations were observed in studies with older individuals, suggesting that there is a positive relationship between age and HR. Conclusion: Although meeting 5 to 7 metrics is associated with the lowest hazard for CVD incidence, meeting 3 to 4 metrics still offers an important protective effect for CVD. Therefore, a realistic goal in the general population in the short term could be to promote at least an intermediate ideal CVH profile (3 to 4 metrics). © 2018 Mayo Foundation for Medical Education and Research

• Fecha de publicación: 2018
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/22563
• Acceso en línea: https://doi.org/10.1016/j.mayocp.2018.05.035; https://repository.urosario.edu.co/handle/10336/22563
• Palabra clave: Adult; Age; Aged; Article; Cardiovascular disease; Cardiovascular risk; Cohort analysis; Hazard ratio; Health; Heart rate; High risk population; Human; Incidence; Major clinical study; Systematic review; Cardiovascular disease; Cardiovascular function; Cardiovascular system; Female; Health status; Male; Meta analysis; Proportional hazards model; Prospective study; Regression analysis; Risk factor; Adult; Age factors; Cardiovascular diseases; Cardiovascular physiological phenomena; Cardiovascular system; Female; Health status; Humans; Male; Proportional hazards models; Prospective studies; Regression analysis; Risk factors
• License: Abierto (Texto Completo)