High rate of cardiac involvement in Colombian patients with Kawasaki Disease

Kawasaki disease (KD) is a systemic vasculitis, whose main complication is the coronary arteries involvement. This was a retrospective study in which 48 Colombian KD patients were included, and the rate and associated factors to cardiac involvement were investigated. The mean time from the first symptom until the diagnosis was 10.5 days. Cardiac involvement was registered in 13 (27%) patients, of whom 10 presented with coronary disease and 3 with a different cardiac manifestations. Forty-one patients (85.4%) received IV immunoglobulin. By multivariate analysis, the patient's age (OR: 0.91, 95% CI: 0.85–0.98, p = 0.01) and the lapse of time between onset of symptoms and diagnosis (OR: 1.21, 95% CI: 1.05–1.41, p = 0.01) were associated factors influencing cardiac involvement and coronary disease, respectively. The high rate of cardiac compromise in Colombian patients agrees with that observed in other Latin American populations. © 2009 Asociación Colombiana de Reumatología

• Fecha de publicación: 2009
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/23065
• Acceso en línea: https://doi.org/10.1016/S0121-8123(09)70110-0; https://repository.urosario.edu.co/handle/10336/23065
• Palabra clave: Immunoglobulin; Age; Article; Clinical article; Colombian; Coronary artery disease; Disease course; Heart disease; Human; Mucocutaneous lymph node syndrome; Prevalence; Retrospective study; Risk factor; South and central america; Associated factors; Childhood; Coronary disease; Kawasaki disease
• License: Abierto (Texto Completo)