Differences in conditional self-discrimination between wistar and Sprague-Dawley strains

Conditional self-discrimination capacity was studied and compared between two strains of 4 weeks old Rattus norvegicus. Each strain (15 Wistar and 16 Sprague-Dawley) was considered as a group, both trained under an escape paradigm in which a lever was associated to presence or absence of methylphenidate. The dependent variable was measured during the phase of extinction. Significant differences were found for self-discrimination capacity, and between groups, being the Sprague-Dawley the strain with a better performance. Even though both strains are able to discriminate their internal state, and learn to use such state as a discriminative stimulus, the social variable seem to be a remarkable component of the differences found in the strains performances.

• Fecha de publicación: 2011
• Institución: Universidad del Rosario
• Repositorio: Repositorio EdocUR - U. Rosario
• Idioma: eng
• OAI Identifier: oai:repository.urosario.edu.co:10336/24324
• Acceso en línea: https://repository.urosario.edu.co/handle/10336/24324
• Palabra clave: Conditional self-discrimination; Social behavior; Sprague-dawley rats; Wistar rats
• License: Abierto (Texto Completo)